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Select item 112477991.

CD11b maintains West Nile virus replication through modulation of immune response in human neuroblastoma cells

Yan-Gang Liu, Hao-Ran Peng, Rui-Wen Ren, Ping Zhao, Lan-Juan Zhao

Virol J. 2024; 21: 158. Published online 2024 Jul 14. doi: 10.1186/s12985-024-02427-6

PMCID:: PMC11247799

Abstract Article PDF–1.5M

Select item 110871012.

ITGAM is a critical gene in ischemic stroke

Lei Hou, Zhongchen Li, Xiaoli Guo, Jiatao Lv, Zonglei Chong, Yilei Xiao, Liyong Zhang, Zefu Li

Aging (Albany NY) 2024 Apr 30; 16(8): 6852–6867. Published online 2024 Apr 17. doi: 10.18632/aging.205729

PMCID:: PMC11087101

Abstract Article PDF–2.1M

Select item 109007063.

ITGAM-mediated macrophages contribute to basement membrane damage in diabetic nephropathy and atherosclerosis

Yude Lou, Peng Hui Li, Xiao Qi Liu, Tian Xiang Wang, Yi Lan Liu, Chen Chen Chen, Kun Ling Ma

BMC Nephrol. 2024; 25: 72. Published online 2024 Feb 27. doi: 10.1186/s12882-024-03505-1

PMCID:: PMC10900706

Abstract Article PDF–6.8M

Select item 102186434.

ITGAM rs1143679 Variant in Systemic Lupus Erythematosus Is Associated with Increased Serum Calcification Propensity

Matthieu Halfon, Li Zhang, Driss Ehirchiou, Vishnuprabu Durairaj Pandian, Suzan Dahdal, Uyen Huynh-Do, Andreas Pasch, Camillo Ribi, Nathalie Busso

Genes (Basel) 2023 May; 14(5): 1105. Published online 2023 May 18. doi: 10.3390/genes14051105

PMCID:: PMC10218643

Abstract Article PDF–551K

Select item 95976555.

Association of monocyte migration marker CD11b with pulmonary function in people living with HIV

Mark H. Kuniholm, Mariam Bramah-Lawani, Meghan Fitzpatrick, Mehdi Nouraie, Shulin Qin, Laurence Huang, Abbe N. Vallejo, Alan L. Landay, Alison Morris

J Acquir Immune Defic Syndr. Author manuscript; available in PMC 2022 Oct 26.

Published in final edited form as: J Acquir Immune Defic Syndr. 2021 Mar 1; 86(3): 344–352. doi: 10.1097/QAI.0000000000002544

PMCID:: PMC9597655

Abstract Article PDF–370K

Select item 87494106.

Complement Receptor 3 Mediates HIV-1 Transcytosis across an Intact Cervical Epithelial Cell Barrier: New Insight into HIV Transmission in Women

Christopher J. Day, Rachael L. Hardison, Belinda L. Spillings, Jessica Poole, Joseph A. Jurcisek, Johnson Mak, Michael P. Jennings, Jennifer L. Edwards

mBio. 2022 Jan-Feb; 13(1): e02177-21. Published online 2022 Jan 11. doi: 10.1128/mbio.02177-21

PMCID:: PMC8749410

Abstract Article PDF–2.9M

Select item 85056257.

Polymorphism of the ITGAM gene (rs7193943) and bioelectric impedance analysis as potential predictors of cachexia in chronic heart failure

Grzegorz Sobieszek, Radosław Mlak, Tomasz Powrózek, Marcin Mazurek, Aneta Skwarek-Dziekanowska, Piotr Terlecki, Teresa Małecka-Massalska

Sci Rep. 2021; 11: 20145. Published online 2021 Oct 11. doi: 10.1038/s41598-021-99719-6

PMCID:: PMC8505625

Abstract Article PDF–888K

Select item 68810228.

ITGAM is a risk factor to systemic lupus erythematosus and possibly a protection factor to rheumatoid arthritis in patients from Mexico

Julian Ramírez-Bello, Celi Sun, Guillermo Valencia-Pacheco, Bhupinder Singh, Rosa Elda Barbosa-Cobos, Miguel A. Saavedra, Ricardo F. López-Villanueva, Swapan K. Nath

PLoS One. 2019; 14(11): e0224543. Published online 2019 Nov 27. doi: 10.1371/journal.pone.0224543

PMCID:: PMC6881022

Abstract Article PDF–498K

Select item 64130989.

Hydroxyethyl Starch 130/0.4 Binds to Neutrophils Impairing Their Chemotaxis through a Mac-1 Dependent Interaction

Alessandro Trentini, Francesca Murganti, Valentina Rosta, Carlo Cervellati, Maria Cristina Manfrinato, Savino Spadaro, Franco Dallocchio, Carlo Alberto Volta, Tiziana Bellini

Int J Mol Sci. 2019 Feb; 20(4): 817. Published online 2019 Feb 14. doi: 10.3390/ijms20040817

PMCID:: PMC6413098

Abstract Article PDF–1.7M

Select item 597223210.

Association of the CD11b rs1143679 polymorphism with systemic lupus erythematosus in the Han Chinese population

Chunmei Li, Fengqing Tong, Yi Ma, Kai Qian, Junyu Zhang, Xingguo Chen

J Int Med Res. 2018 Mar; 46(3): 1008–1014. Published online 2017 Dec 6. doi: 10.1177/0300060517719210

PMCID:: PMC5972232

Abstract Article PDF–216K

Select item 507485111.

The pathogenic relevance of α_M-integrin in Guillain-Barré syndrome

Chaoling Dong, Steven P. Palladino, Eric Scott Helton, Eroboghene E. Ubogu

Acta Neuropathol. Author manuscript; available in PMC 2017 Nov 1.

Published in final edited form as: Acta Neuropathol. 2016 Nov; 132(5): 739–752. Published online 2016 Jul 26. doi: 10.1007/s00401-016-1599-0

PMCID:: PMC5074851

Abstract Article PDF–2.2M

Select item 455024412.

Prognostic Value of CD11b Expression Level for Acute Myeloid Leukemia Patients: A Meta-Analysis

Shuangnian Xu, Xi Li, Jianmin Zhang, Jieping Chen

PLoS One. 2015; 10(8): e0135981. Published online 2015 Aug 26. doi: 10.1371/journal.pone.0135981

PMCID:: PMC4550244

Abstract Article PDF–642K

Select item 448111713.

The opioid peptide dynorphin A induces leukocyte responses via integrin Mac-1 (α_Mβ₂, CD11b/CD18)

Nataly P. Podolnikova, Julie A. Brothwell, Tatiana P. Ugarova

Mol Pain. 2015; 11: 33. Published online 2015 Jun 3. doi: 10.1186/s12990-015-0027-0

PMCID:: PMC4481117

Abstract Article PDF–2.2M

Select item 408236314.

Combined protein- and nucleic acid-level effects of rs1143679 (R77H), a lupus-predisposing variant within ITGAM

Amit K. Maiti, Xana Kim-Howard, Prasenjeet Motghare, Vandana Pradhan, Kek Heng Chua, Celi Sun, María Teresa Arango-Guerrero, Kanjaksha Ghosh, Timothy B. Niewold, John B. Harley, Juan-Manual Anaya, Loren L. Looger, Swapan K. Nath

Hum Mol Genet. 2014 Aug 1; 23(15): 4161–4176. Published online 2014 Mar 7. doi: 10.1093/hmg/ddu106

PMCID:: PMC4082363

Abstract Article PDF–788K

Select item 406045015.

Resequencing the susceptibility gene, ITGAM, identifies two functionally deleterious rare variants in systemic lupus erythematosus cases

Amy L Roberts, Ellen RA Thomas, Shriram Bhosle, Laurence Game, Olga Obraztsova, Timothy J Aitman, Timothy J Vyse, Benjamin Rhodes

Arthritis Res Ther. 2014; 16(3): R114. Published online 2014 May 21. doi: 10.1186/ar4566

PMCID:: PMC4060450

Abstract Article PDF–927K

Select item 396902816.

Multiple Lupus Associated ITGAM Variants Alter Mac-1 Function on Neutrophils

Yebin Zhou, Jianming Wu, Dennis F. Kucik, Nathan B. White, David T. Redden, Alexander J. Szalai, Daniel C. Bullard, Jeffrey C. Edberg

Arthritis Rheum. Author manuscript; available in PMC 2014 Nov 1.

Published in final edited form as: Arthritis Rheum. 2013 Nov; 65(11): 2907–2916. doi: 10.1002/art.38117

PMCID:: PMC3969028

Abstract Article PDF–668K

Select item 369677217.

Staphylococcus aureus LukAB cytotoxin kills human neutrophils by targeting the CD11b subunit of the integrin Mac-1

Ashley L. DuMont, Pauline Yoong, Christopher J. Day, Francis Alonzo, III, W. Hayes McDonald, Michael P. Jennings, Victor J. Torres

Proc Natl Acad Sci U S A. 2013 Jun 25; 110(26): 10794–10799. Published online 2013 Jun 10. doi: 10.1073/pnas.1305121110

PMCID:: PMC3696772

Abstract Article PDF–789K

Select item 353180718.

Pilus Adhesin RrgA Interacts with Complement Receptor 3, Thereby Affecting Macrophage Function and Systemic Pneumococcal Disease

Sofia Orrskog, Samuli Rounioja, Tiziana Spadafina, Marilena Gallotta, Martin Norman, Karina Hentrich, Stefan Fälker, Sofia Ygberg-Eriksson, Mike Hasenberg, Björn Johansson, Liisa M. Uotila, Carl G. Gahmberg, Michèle Barocchi, Matthias Gunzer, Staffan Normark, Birgitta Henriques-Normark

mBio. 2013 Jan-Feb; 4(1): e00535-12. Published online 2012 Dec 26. doi: 10.1128/mBio.00535-12

PMCID:: PMC3531807

Abstract Article PDF–2.1M

Select item 348876319.

The rs1143679 (R77H) lupus associated variant of ITGAM (CD11b) impairs complement receptor 3 mediated functions in human monocytes

Benjamin Rhodes, Barbara G Fürnrohr, Amy L Roberts, George Tzircotis, Georg Schett, Tim D Spector, Timothy J Vyse

Ann Rheum Dis. 2012 Dec; 71(12): 2028–2034. Published online 2012 May 14. doi: 10.1136/annrheumdis-2012-201390

PMCID:: PMC3488763

Abstract Article PDF–669K

Select item 322418820.

Evaluation of genetic association between an ITGAM non-synonymous SNP (rs1143679) and multiple autoimmune diseases

Juan-Manuel Anaya, Xana Kim-Howard, Sampath Prahalad, Alejandra Cherñavsky, Carlos Cañas, Adriana Rojas-Villarraga, John Bohnsack, Roland Jonsson, Anne Isine Bolstad, Johan G Brun, Beth Cobb, Kathy L. Moser, Judith A. James, John B. Harley, Swapan K. Nath

Autoimmun Rev. Author manuscript; available in PMC 2013 Feb 1.

Published in final edited form as: Autoimmun Rev. 2012 Feb; 11(4): 276–280. Published online 2011 Aug 5. doi: 10.1016/j.autrev.2011.07.007

PMCID:: PMC3224188

Abstract Article PDF–509K

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