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Select item 47230591.

Association of IREB2 Gene rs2568494 Polymorphism with Risk of Chronic Obstructive Pulmonary Disease: A Meta-Analysis

Yiming Du, Yuwen Xue, Wei Xiao

Med Sci Monit. 2016; 22: 177–182. Published online 2016 Jan 18. doi: 10.12659/MSM.894524

PMCID:: PMC4723059

Abstract Article PDF–445K

Select item 39892902.

IRP2 regulates breast tumor growth

Wei Wang, Zhiyong Deng, Heather Hatcher, Lance D. Miller, Xiumin Di, Lia Tesfay, Guangchao Sui, Ralph B. D'Agostino, Jr., Frank M. Torti, Suzy V. Torti

Cancer Res. Author manuscript; available in PMC 2015 Jan 15.

Published in final edited form as: Cancer Res. 2014 Jan 15; 74(2): 497–507. Published online 2013 Nov 27. doi: 10.1158/0008-5472.CAN-13-1224

PMCID:: PMC3989290

Abstract Article PDF–1.1M

Select item 31291503.

Iron Regulatory Protein 2 Turnover through a Nonproteasomal Pathway

Allen H. K. Chang, Jinsook Jeong, Rodney L. Levine

J Biol Chem. 2011 Jul 8; 286(27): 23698–23707. Published online 2011 May 10. doi: 10.1074/jbc.M110.216788

PMCID:: PMC3129150

Abstract Article PDF–3.3M

Select item 28541384.

Tumorigenic Properties of Iron Regulatory Protein 2 (IRP2) Mediated by Its Specific 73-Amino Acids Insert

Carmen Maffettone, Guohua Chen, Ignat Drozdov, Christos Ouzounis, Kostas Pantopoulos

PLoS One. 2010; 5(4): e10163. Published online 2010 Apr 13. doi: 10.1371/journal.pone.0010163

PMCID:: PMC2854138

Abstract Article PDF–1.1M

Select item 27565475.

Integration of Genomic and Genetic Approaches Implicates IREB2 as a COPD Susceptibility Gene

Dawn L. DeMeo, Thomas Mariani, Soumyaroop Bhattacharya, Sorachai Srisuma, Christoph Lange, Augusto Litonjua, Raphael Bueno, Sreekumar G. Pillai, David A. Lomas, David Sparrow, Steven D. Shapiro, Gerard J. Criner, Hong P. Kim, Zhihua Chen, Augustine M.K. Choi, John Reilly, Edwin K. Silverman

Am J Hum Genet. 2009 Oct 9; 85(4): 493–502. doi: 10.1016/j.ajhg.2009.09.004

PMCID:: PMC2756547

Abstract Article PDF–861K

Select item 22673636.

Human iron regulatory protein 2 is easily cleaved in its specific domain: consequences for the haem binding properties of the protein

Camille Dycke, Catherine Bougault, Jacques Gaillard, Jean-Pierre Andrieu, Kostas Pantopoulos, Jean-Marc Moulis

Biochem J. 2007 Dec 15; 408(Pt 3): 429–439. Prepublished online 2007 Aug 31. Published online 2007 Nov 28. doi: 10.1042/BJ20070983

PMCID:: PMC2267363

Abstract Article PDF–451K

Select item 3946447.

Requirements for iron-regulated degradation of the RNA binding protein, iron regulatory protein 2.

K Iwai, R D Klausner, T A Rouault

EMBO J. 1995 Nov 1; 14(21): 5350–5357. doi: 10.1002/j.1460-2075.1995.tb00219.x

PMCID:: PMC394644

Summary Page Browse PDF–1.8M

Select item 3033428.

S-Nitrosylation of IRP2 Regulates Its Stability via the Ubiquitin-Proteasome Pathway

Sangwon Kim, Simon S. Wing, Prem Ponka

Mol Cell Biol. 2004 Jan; 24(1): 330–337. doi: 10.1128/MCB.24.1.330-337.2004

PMCID:: PMC303342

Abstract Article PDF–330K

Select item 98144509.

KLF14 regulates the growth of hepatocellular carcinoma cells via its modulation of iron homeostasis through the repression of iron-responsive element-binding protein 2

Hui Zhou, Junru Chen, Mingjie Fan, Huajian Cai, Yufei Dong, Yue Qiu, Qianqian Zhuang, Zhaoying Lei, Mengyao Li, Xue Ding, Peng Yan, Aifu Lin, Shusen Zheng, Qingfeng Yan

J Exp Clin Cancer Res. 2023; 42: 5. Published online 2023 Jan 5. doi: 10.1186/s13046-022-02562-4

PMCID:: PMC9814450

Abstract Article PDF–14M

Select item 927593010.

MiR-19a suppresses ferroptosis of colorectal cancer cells by targeting IREB2

Hongwei Fan, Rong Ai, Suen Mu, Xuemin Niu, Zhengrong Guo, Lin Liu

Bioengineered. 2022; 13(5): 12021–12029. Published online 2022 May 21. doi: 10.1080/21655979.2022.2054194

PMCID:: PMC9275930

Abstract Article PDF–1.9M

Select item 712213111.

Iron regulatory protein 2 is a suppressor of mutant p53 in tumorigenesis

Yanhong Zhang, Xiuli Feng, Jin Zhang, Minyi Chen, Eric Huang, Xinbin Chen

Oncogene. Author manuscript; available in PMC 2020 Apr 3.

Published in final edited form as: Oncogene. 2019 Aug; 38(35): 6256–6269. Published online 2019 Jul 22. doi: 10.1038/s41388-019-0876-5

PMCID:: PMC7122131

Abstract Article PDF–3.8M

Select item 648733712.

Absence of iron-responsive element-binding protein 2 causes a novel neurodegenerative syndrome

Gregory Costain, Manik C Ghosh, Nunziata Maio, Amanda Carnevale, Yue C Si, Tracey A Rouault, Grace Yoon

Brain. 2019 May; 142(5): 1195–1202. Published online 2019 Mar 26. doi: 10.1093/brain/awz072

PMCID:: PMC6487337

Abstract Article PDF–1022K

Select item 597339713.

Genetic variants in FAM13A and IREB2 are associated with the susceptibility to COPD in a Chinese rural population: a case-control study

Yanan Zhang, Jie Qiu, Peng Zhang, Jin Zhang, Min Jiang, Zhanbing Ma

Int J Chron Obstruct Pulmon Dis. 2018; 13: 1735–1745. Published online 2018 May 25. doi: 10.2147/COPD.S162241

PMCID:: PMC5973397

Abstract Article PDF–496K

Select item 548008114.

BRAF mutations are associated with increased iron regulatory protein‐2 expression in colorectal tumorigenesis

Richard D. Horniblow, Matthew Bedford, Robert Hollingworth, Sarah Evans, Emily Sutton, Neeraj Lal, Andrew Beggs, Tariq H. Iqbal, Chris Tselepis

Cancer Sci. 2017 Jun; 108(6): 1135–1143. Published online 2017 Jun 2. doi: 10.1111/cas.13234

PMCID:: PMC5480081

Abstract Article PDF–1.3M

Select item 455091515.

Susceptibility loci in lung cancer and COPD: association of IREB2 and FAM13A with pulmonary diseases

Iwona Ziółkowska-Suchanek, Maria Mosor, Piotr Gabryel, Marcin Grabicki, Magdalena Żurawek, Marta Fichna, Ewa Strauss, Halina Batura-Gabryel, Wojciech Dyszkiewicz, Jerzy Nowak

Sci Rep. 2015; 5: 13502. Published online 2015 Aug 27. doi: 10.1038/srep13502

PMCID:: PMC4550915

Abstract Article PDF–731K

Select item 391685916.

Iron Transport through Ferroportin Is Induced by Intracellular Ascorbate and Involves IRP2 and HIF2α

Nathalie Scheers, Ann-Sofie Sandberg

Nutrients. 2014 Jan; 6(1): 249–260. Published online 2014 Jan 3. doi: 10.3390/nu6010249

PMCID:: PMC3916859

Abstract Article PDF–1.4M

Select item 333449117.

Genetic polymorphism of the iron-regulatory protein-1 and -2 genes in age-related macular degeneration

Ewelina Synowiec, Magdalena Pogorzelska, Janusz Blasiak, Jerzy Szaflik, Jacek Pawel Szaflik

Mol Biol Rep. 2012; 39(6): 7077–7087. Published online 2012 Feb 14. doi: 10.1007/s11033-012-1539-6

PMCID:: PMC3334491

Abstract Article PDF–265K

Select item 304729618.

The role of IREB2 and transforming growth factor beta-1 genetic variants in COPD: a replication case-control study

Sally L Chappell, Leslie Daly, Juzer Lotya, Aiman Alsaegh, Tamar Guetta-Baranes, Josep Roca, Roberto Rabinovich, Kevin Morgan, Ann B Millar, Seamas C Donnelly, Vera Keatings, William MacNee, Jan Stolk, Pieter S Hiemstra, Massimo Miniati, Simonetta Monti, Clare M O'Connor, Noor Kalsheker

BMC Med Genet. 2011; 12: 24. Published online 2011 Feb 14. doi: 10.1186/1471-2350-12-24