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Select item 73248481.

Differential Activation of P-TEFb Complexes in the Development of Cardiomyocyte Hypertrophy following Activation of Distinct G Protein-Coupled Receptors

Ryan D. Martin, Yalin Sun, Sarah MacKinnon, Luca Cuccia, Viviane Pagé, Terence E. Hébert, Jason C. Tanny

Mol Cell Biol. 2020 Jul; 40(14): e00048-20. Prepublished online 2020 Apr 27. Published online 2020 Jun 29. doi: 10.1128/MCB.00048-20

PMCID:: PMC7324848

Abstract Article PDF–3.6M

Select item 29004992.

55K isoform of CDK9 associates with Ku70 and is involved in DNA repair

Hongbing Liu, Christine H. Herrmann, Karen Chiang, Tzu-Ling Sung, Sung-Hwan Moon, Lawrence A. Donehower, Andrew P. Rice

Biochem Biophys Res Commun. Author manuscript; available in PMC 2011 Jun 25.

Published in final edited form as: Biochem Biophys Res Commun. 2010 Jun 25; 397(2): 245–250. Published online 2010 May 20. doi: 10.1016/j.bbrc.2010.05.092

PMCID:: PMC2900499

Abstract Article PDF–838K

Select item 53895383.

SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription

Maximilian F. Blank, Sifan Chen, Fabian Poetz, Martina Schnölzer, Renate Voit, Ingrid Grummt

Nucleic Acids Res. 2017 Mar 17; 45(5): 2675–2686. Published online 2017 Jan 30. doi: 10.1093/nar/gkx053

PMCID:: PMC5389538

Abstract Article PDF–2.2M

Select item 22684154.

Acetylation of Conserved Lysines in the Catalytic Core of Cyclin-Dependent Kinase 9 Inhibits Kinase Activity and Regulates Transcription

Arianna Sabò, Marina Lusic, Anna Cereseto, Mauro Giacca

Mol Cell Biol. 2008 Apr; 28(7): 2201–2212. Published online 2008 Feb 4. doi: 10.1128/MCB.01557-07

PMCID:: PMC2268415

Abstract Article PDF–882K

Select item 5166245.

Activation of cardiac Cdk9 represses PGC-1 and confers a predisposition to heart failure

Motoaki Sano, Sam C Wang, Manabu Shirai, Fernando Scaglia, Min Xie, Satoshi Sakai, Toru Tanaka, Prathit A Kulkarni, Philip M Barger, Keith A Youker, George E Taffet, Yasuo Hamamori, Lloyd H Michael, William J Craigen, Michael D Schneider

EMBO J. 2004 Sep 1; 23(17): 3559–3569. Published online 2004 Aug 5. doi: 10.1038/sj.emboj.7600351

PMCID:: PMC516624

Abstract Article PDF–606K

Select item 33450096.

BRD4 is an atypical kinase that phosphorylates Serine2 of the RNA Polymerase II carboxy-terminal domain

Ballachanda N. Devaiah, Brian A. Lewis, Natasha Cherman, Michael C. Hewitt, Brian K. Albrecht, Pamela G. Robey, Keiko Ozato, Robert J. Sims, III, Dinah S. Singer

Proc Natl Acad Sci U S A. 2012 May 1; 109(18): 6927–6932. Published online 2012 Apr 16. doi: 10.1073/pnas.1120422109

PMCID:: PMC3345009

Abstract Article PDF–719K

Select item 29669567.

Cyclin-dependent kinase 9–cyclin K functions in the replication stress response

David S Yu, Runxiang Zhao, Emory L Hsu, Jennifer Cayer, Fei Ye, Yan Guo, Yu Shyr, David Cortez

EMBO Rep. 2010 Nov; 11(11): 876–882. Published online 2010 Oct 8. doi: 10.1038/embor.2010.153

PMCID:: PMC2966956

Abstract Article PDF–788K

Select item 11320078.

A human splicing factor, SKIP, associates with P-TEFb and enhances transcription elongation by HIV-1 Tat

Vanessa Brès, Nathan Gomes, Loni Pickle, Katherine A. Jones

Genes Dev. 2005 May 15; 19(10): 1211–1226. doi: 10.1101/gad.1291705

PMCID:: PMC1132007

Abstract Article PDF–1.0M

Select item 29538399.

Multiple functions of Ldb1 required for β-globin activation during erythroid differentiation

Sang-Hyun Song, AeRi Kim, Tobias Ragoczy, M. A. Bender, Mark Groudine, Ann Dean

Blood. 2010 Sep 30; 116(13): 2356–2364. Prepublished online 2010 Jun 22. doi: 10.1182/blood-2010-03-272252

PMCID:: PMC2953839

Abstract Article

Select item 31658110.

Identification of multiple cyclin subunits of human P-TEFb

Junmin Peng, Yuerong Zhu, Jeffrey T. Milton, David H. Price

Genes Dev. 1998 Mar 1; 12(5): 755–762. doi: 10.1101/gad.12.5.755

PMCID:: PMC316581

Abstract Article PDF–736K

Select item 340814711.

Cyclin K-containing Kinase Complexes Maintain Self-renewal in Murine Embryonic Stem Cells

Qian Dai, Tingjun Lei, Changhong Zhao, Jianqiao Zhong, Yi-zhi Tang, Bin Chen, Jie Yang, Chenghua Li, Siyu Wang, Xu Song, Li Li, Qintong Li

J Biol Chem. 2012 Jul 20; 287(30): 25344–25352. Published online 2012 Apr 30. doi: 10.1074/jbc.M111.321760

PMCID:: PMC3408147

Abstract Article PDF–2.1M

Select item 284320612.

Cyclin-dependent Kinase-9 Is a Component of the p300/GATA4 Complex Required for Phenylephrine-induced Hypertrophy in Cardiomyocytes

Yoichi Sunagawa, Tatsuya Morimoto, Tomohide Takaya, Shinji Kaichi, Hiromichi Wada, Teruhisa Kawamura, Masatoshi Fujita, Akira Shimatsu, Toru Kita, Koji Hasegawa

J Biol Chem. 2010 Mar 26; 285(13): 9556–9568. Published online 2010 Jan 17. doi: 10.1074/jbc.M109.070458

PMCID:: PMC2843206

Abstract Article PDF–2.6M

Select item 369040213.

The methyltransferase SMYD3 mediates the recruitment of transcriptional cofactors at the myostatin and c-Met genes and regulates skeletal muscle atrophy

Valentina Proserpio, Raffaella Fittipaldi, James G. Ryall, Vittorio Sartorelli, Giuseppina Caretti

Genes Dev. 2013 Jun 1; 27(11): 1299–1312. doi: 10.1101/gad.217240.113

PMCID:: PMC3690402

Abstract Article PDF–2.4M

Select item 272667714.

CDK9 directs H2B monoubiquitination and controls replication-dependent histone mRNA 3′-end processing

Judith Pirngruber, Andrei Shchebet, Lisa Schreiber, Efrat Shema, Neri Minsky, Rob D Chapman, Dirk Eick, Yael Aylon, Moshe Oren, Steven A Johnsen

EMBO Rep. 2009 Aug; 10(8): 894–900. Published online 2009 Jul 3. doi: 10.1038/embor.2009.108

PMCID:: PMC2726677

Abstract Article PDF–609K

Select item 397479715.

Control of Transcriptional Elongation

Hojoong Kwak, John T. Lis

Annu Rev Genet. Author manuscript; available in PMC 2014 Apr 3.

Published in final edited form as: Annu Rev Genet. 2013; 47: 483–508. Published online 2013 Sep 11. doi: 10.1146/annurev-genet-110711-155440

PMCID:: PMC3974797

Abstract Article PDF–1.7M

Select item 308944816.

Ikaros interacts with P-TEFb and cooperates with GATA-1 to enhance transcription elongation

Stefania Bottardi, Farah A. Zmiri, Vincent Bourgoin, Julie Ross, Lionel Mavoungou, Eric Milot

Nucleic Acids Res. 2011 May; 39(9): 3505–3519. Published online 2011 Jan 17. doi: 10.1093/nar/gkq1271

PMCID:: PMC3089448

Abstract Article PDF–8.0M

Select item 350581817.

Cell cycle gene-specific control of transcription has a critical role in proliferation of primordial germ cells

Daiji Okamura, Ikuma Maeda, Hirofumi Taniguchi, Yuko Tokitake, Makiko Ikeda, Keiko Ozato, Nathan Mise, Kuniya Abe, Toshiaki Noce, Juan Carlos Izpisua Belmonte, Yasuhisa Matsui

Genes Dev. 2012 Nov 15; 26(22): 2477–2482. doi: 10.1101/gad.202242.112

PMCID:: PMC3505818

Abstract Article PDF–663K

Select item 324983518.

The little elongation complex (LEC) regulates small nuclear RNA transcription

Edwin R. Smith, Chengqi Lin, Alexander S. Garrett, Janet Thornton, Nima Mohaghegh, Deqing Hu, Jessica Jackson, Anita Saraf, Selene K. Swanson, Christopher Seidel, Laurence Florens, Michael P. Washburn, Joel C. Eissenberg, Ali Shilatifard

Mol Cell. Author manuscript; available in PMC 2012 Dec 23.

Published in final edited form as: Mol Cell. 2011 Dec 23; 44(6): 954–965. doi: 10.1016/j.molcel.2011.12.008