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Select item 52885731.

A Homeostatic Shift Facilitates Endoplasmic Reticulum Proteostasis through Transcriptional Integration of Proteostatic Stress Response Pathways

Liam Baird, Tadayuki Tsujita, Eri H. Kobayashi, Ryo Funayama, Takeshi Nagashima, Keiko Nakayama, Masayuki Yamamoto

Mol Cell Biol. 2017 Feb 15; 37(4): e00439-16. Prepublished online 2016 Dec 5. Published online 2017 Feb 1. doi: 10.1128/MCB.00439-16

PMCID:: PMC5288573

Abstract Article PDF–1.8M

Select item 43739142.

Icariin Induces Synoviolin Expression through NFE2L1 to Protect Neurons from ER Stress-Induced Apoptosis

Fei Li, Beixue Gao, Hongxin Dong, Jingshan Shi, Deyu Fang

PLoS One. 2015; 10(3): e0119955. Published online 2015 Mar 25. doi: 10.1371/journal.pone.0119955

PMCID:: PMC4373914

Abstract Article PDF–727K

Select item 41886133.

The C-Terminal Domain of Nrf1 Negatively Regulates the Full-Length CNC-bZIP Factor and Its Shorter Isoform LCR-F1/Nrf1β; Both Are Also Inhibited by the Small Dominant-Negative Nrf1γ/δ Isoforms that Down-Regulate ARE-Battery Gene Expression

Yiguo Zhang, Lu Qiu, Shaojun Li, Yuancai Xiang, Jiayu Chen, Yonggang Ren

PLoS One. 2014; 9(10): e109159. Published online 2014 Oct 7. doi: 10.1371/journal.pone.0109159

PMCID:: PMC4188613

Abstract Article PDF–9.5M

Select item 38351804.

Nuclear factor-erythroid 2-related factor 1 regulates expression of proteasome genes in hepatocytes and protects against endoplasmic reticulum stress and steatosis in mice

Candy S. Lee, Daniel V. Ho, Jefferson Y. Chan

FEBS J. Author manuscript; available in PMC 2014 Aug 1.

Published in final edited form as: FEBS J. 2013 Aug; 280(15): 10.1111/febs.12350. Published online 2013 Jun 18. doi: 10.1111/febs.12350

PMCID:: PMC3835180

Abstract Article PDF–1.0M

Select item 38351925.

Deficiency in the nuclear related factor erythroid-2 transcription factor (Nrf1) leads to genetic instability

Diane H. Oh, Diamanda Rigas, Ara Cho, Jefferson Y. Chan

FEBS J. Author manuscript; available in PMC 2013 Nov 20.

Published in final edited form as: FEBS J. 2012 Nov; 279(22): 10.1111/febs.12005. Published online 2012 Oct 4. doi: 10.1111/febs.12005

PMCID:: PMC3835192

Abstract Article PDF–1.4M

Select item 11688156.

Nrf1 and Nrf2 Regulate Rat Glutamate-Cysteine Ligase Catalytic Subunit Transcription Indirectly via NF-κB and AP-1

Heping Yang, Nathaniel Magilnick, Candy Lee, Denise Kalmaz, Xiaopeng Ou, Jefferson Y. Chan, Shelly C. Lu

Mol Cell Biol. 2005 Jul; 25(14): 5933–5946. doi: 10.1128/MCB.25.14.5933-5946.2005

PMCID:: PMC1168815

Abstract Article PDF–706K

Select item 41877197.

Transcription Factor Nrf1 Negatively Regulates the Cystine/Glutamate Transporter and Lipid-Metabolizing Enzymes

Tadayuki Tsujita, Vivian Peirce, Liam Baird, Yuka Matsuyama, Misaki Takaku, Shawn V. Walsh, Julian L. Griffin, Akira Uruno, Masayuki Yamamoto, John D. Hayes

Mol Cell Biol. 2014 Oct; 34(20): 3800–3816. doi: 10.1128/MCB.00110-14

PMCID:: PMC4187719

Abstract Article PDF–3.1M

Select item 39096488.

Expression Profiling of Aldh1l1-Precursors in the Developing Spinal Cord Reveals Glial Lineage-Specific Genes and Direct Sox9-Nfe2l1 Interactions

Anna V. Molofsky, Stacey M. Glasgow, Lesley S. Chaboub, Hui-Hsin Tsai, Alice T. Murnen, Kevin W. Kelley, Stephen P.J. Fancy, Tracy J. Yuen, Lohith Madireddy, Sergio Baranzini, Benjamin Deneen, David H. Rowitch, Michael C. Oldham

Glia. Author manuscript; available in PMC 2014 Mar 1.

Published in final edited form as: Glia. 2013 Sep; 61(9): 1518–1532. Published online 2013 Jul 10. doi: 10.1002/glia.22538

PMCID:: PMC3909648

Abstract Article PDF–3.5M

Select item 38969449.

p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition

Senthil K Radhakrishnan, Willem den Besten, Raymond J Deshaies

eLife. 2014; 3: e01856. Published online 2014 Jan 21. doi: 10.7554/eLife.01856

PMCID:: PMC3896944

Abstract Article PDF–3.0M

Select item 348317110.

Characterization of Nrf1b, a Novel Isoform of the Nuclear Factor-Erythroid-2 Related Transcription Factor-1 That Activates Antioxidant Response Element-Regulated Genes

Eric K. Kwong, Kyung-Mi Kim, Patrick J. Penalosa, Jefferson Y. Chan

PLoS One. 2012; 7(10): e48404. Published online 2012 Oct 29. doi: 10.1371/journal.pone.0048404

PMCID:: PMC3483171

Abstract Article PDF–1.4M

Select item 306973611.

New targets of urocortin-mediated cardioprotection

Seán P Barry, Kevin M Lawrence, James McCormick, Surinder M Soond, Mike Hubank, Simon Eaton, Ahila Sivarajah, Tiziano M Scarabelli, Richard A Knight, Christoph Thiemermann, David S Latchman, Paul A Townsend, Anastasis Stephanou

J Mol Endocrinol. 2010 Aug; 45(2): 69–85. Prepublished online 2010 May 25. doi: 10.1677/JME-09-0148

PMCID:: PMC3069736

Abstract Article PDF–317K

Select item 287468512.

Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells

Senthil K. Radhakrishnan, Candy S. Lee, Patrick Young, Anne Beskow, Jefferson Y. Chan, Raymond J. Deshaies

Mol Cell. Author manuscript; available in PMC 2010 Oct 9.

Published in final edited form as: Mol Cell. 2010 Apr 9; 38(1): 17–28. doi: 10.1016/j.molcel.2010.02.029

PMCID:: PMC2874685

Abstract Article PDF–2.7M

Select item 117052513.

Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice.

J Y Chan, M Kwong, R Lu, J Chang, B Wang, T S Yen, Y W Kan

EMBO J. 1998 Mar 16; 17(6): 1779–1787. doi: 10.1093/emboj/17.6.1779

PMCID:: PMC1170525

Summary PDF–588K

Select item 14727014.

Interaction of the CNC-bZIP factor TCF11/LCR-F1/Nrf1 with MafG: binding-site selection and regulation of transcription.

O Johnsen, P Murphy, H Prydz, A B Kolsto

Nucleic Acids Res. 1998 Jan 15; 26(2): 512–520. doi: 10.1093/nar/26.2.512

PMCID:: PMC147270

Summary PDF–355K

Select item 1008480915.

Induction of Herpud1 expression by ER stress is regulated by Nrf1

Daniel V. Ho, Jefferson Y. Chan

FEBS Lett. Author manuscript; available in PMC 2023 Apr 10.

Published in final edited form as: FEBS Lett. 2015 Feb 27; 589(5): 615–620. Published online 2015 Jan 28. doi: 10.1016/j.febslet.2015.01.026

PMCID:: PMC10084809

Abstract Article PDF–2.0M

Select item 583999316.

Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity

Alexander Bartelt, Scott B. Widenmaier, Christian Schlein, Kornelia Johann, Renata L. S. Goncalves, Kosei Eguchi, Alexander W. Fischer, Günes Parlakgül, Nicole A. Snyder, Truc B. Nguyen, Oliver T. Bruns, Daniel Franke, Moungi G. Bawendi, Matthew D. Lynes, Luiz O. Leiria, Yu-Hua Tseng, Karen E. Inouye, Ana Paula Arruda, Gökhan S. Hotamisligil

Nat Med. Author manuscript; available in PMC 2018 Aug 5.

Published in final edited form as: Nat Med. 2018 Mar; 24(3): 292–303. Published online 2018 Feb 5. doi: 10.1038/nm.4481