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Select item 98204141.

Functional Heterodimerization between the G Protein-Coupled Receptor GPR17 and the Chemokine Receptors 2 and 4: New Evidence

Simona Daniele, Simona Saporiti, Stefano Capaldi, Deborah Pietrobono, Lara Russo, Uliano Guerrini, Tommaso Laurenzi, Elham Ataie Kachoie, Luca Palazzolo, Vincenzo Russo, Maria Pia Abbracchio, Ivano Eberini, Maria Letizia Trincavelli

Int J Mol Sci. 2023 Jan; 24(1): 261. Published online 2022 Dec 23. doi: 10.3390/ijms24010261

PMCID:: PMC9820414

Abstract Article PDF–5.2M

Select item 97487222.

Hyperactive immature state and differential CXCR2 expression of neutrophils in severe COVID-19

Christopher M Rice, Philip Lewis, Fernando M Ponce-Garcia, Willem Gibbs, Sarah Groves, Drinalda Cela, Fergus Hamilton, David Arnold, Catherine Hyams, Elizabeth Oliver, Rachael Barr, Anu Goenka, Andrew Davidson, Linda Wooldridge, Adam Finn, Laura Rivino, Borko Amulic

Life Sci Alliance. 2023 Feb; 6(2): e202201658. Published online 2022 Dec 13. doi: 10.26508/lsa.202201658

PMCID:: PMC9748722

Abstract Article PDF–2.0M

Select item 97162293.

CXC‐ receptor 2 promotes extracellular matrix production and attenuates migration in peripapillary human scleral fibroblasts under mechanical strain

Chen Qiu, Chuandong Wang, Xinghuai Sun, Jianjiang Xu, Jihong Wu, Rong Zhang, Gang Li, Kang Xue, Xiaoling Zhang, Shaohong Qian

J Cell Mol Med. 2022 Dec; 26(23): 5858–5871. Published online 2022 Nov 8. doi: 10.1111/jcmm.17609

PMCID:: PMC9716229

Abstract Article PDF–28M

Select item 92513824.

Neutrophil Infiltration Characterized by Upregulation of S100A8, S100A9, S100A12 and CXCR2 Is Associated With the Co-Occurrence of Crohn’s Disease and Peripheral Artery Disease

Ziping Yao, Bihui Zhang, Guochen Niu, Ziguang Yan, Xiaoqiang Tong, Yinghua Zou, Yuan Li, Min Yang

Front Immunol. 2022; 13: 896645. Published online 2022 Jun 20. doi: 10.3389/fimmu.2022.896645

PMCID:: PMC9251382

Abstract Article PDF–5.4M

Select item 92452425.

Transient post-operative overexpression of CXCR2 on monocytes of traumatic brain injury patients drives monocyte chemotaxis toward cerebrospinal fluid and enhances monocyte-mediated immunogenic cell death of neurons in vitro

Huayang Wang, Qibing Huang, Zhijie Zhang, Jian Ji, Tao Sun, Donghai Wang

J Neuroinflammation. 2022; 19: 171. Published online 2022 Jun 29. doi: 10.1186/s12974-022-02535-6

PMCID:: PMC9245242

Abstract Article PDF–7.4M

Select item 89794346.

CXCR2 signaling might have a tumor-suppressive role in patients with cholangiocarcinoma

Yurie Yamamoto, Atsushi Sugimoto, Koji Maruo, Gen Tsujio, Tomohiro Sera, Shuhei Kushiyama, Sadaaki Nishimura, Kenji Kuroda, Shingo Togano, Shinpei Eguchi, Ryota Tanaka, Kenjiro Kimura, Ryosuke Amano, Masaichi Ohira, Masakazu Yashiro

PLoS One. 2022; 17(4): e0266027. Published online 2022 Apr 4. doi: 10.1371/journal.pone.0266027

PMCID:: PMC8979434

Abstract Article PDF–1.3M

Select item 89550447.

A C-X-C chemokine receptor type 2-dominated crosstalk between tumor cells and macrophages drives gastric cancer metastasis

Zhijun Zhou, Guanggai Xia, Zhen Xiang, Mingyang Liu, Zhewei Wei, Jie Yan, Wei Chen, Jintao Zhu, Niranjan Awasthi, Xiaotian Sun, Kar-Ming Fung, Yulong He, Min Li, Changhua Zhang

Clin Cancer Res. Author manuscript; available in PMC 2022 Mar 25.

Published in final edited form as: Clin Cancer Res. 2019 Jun 1; 25(11): 3317–3328. Published online 2019 Feb 22. doi: 10.1158/1078-0432.CCR-18-3567

PMCID:: PMC8955044

Abstract Article PDF–1.1M

Select item 88835558.

Biallelic CXCR2 loss-of-function mutations define a distinct congenital neutropenia entity

Viviana Marin-Esteban, Jenny Youn, Blandine Beaupain, Agnieszka Jaracz-Ros, Vincent Barlogis, Odile Fenneteau, Thierry Leblanc, Florence Bellanger, Philippe Pellet, Julien Buratti, Hélène Lapillonne, Françoise Bachelerie, Jean Donadieu, Christine Bellanné-Chantelot

Haematologica. 2022 Mar 1; 107(3): 765–769. Published online 2021 Dec 2. doi: 10.3324/haematol.2021.279254

PMCID:: PMC8883555

Article PDF–1.1M

Select item 88786319.

Association between IL8RB C1208T mutation and risk of cancer: A pooled analysis based on 5299 cases and 6899 controls

He-Yun Sun, Zhi-Chao Min, Lei Gao, Zi-Yi Zhang, Ting-Le Pang, Ying-Jun Gao, Hong Pan, Jun Ou-Yang

Medicine (Baltimore) 2022 Feb 25; 101(8): e28986. Published online 2022 Feb 25. doi: 10.1097/MD.0000000000028986

PMCID:: PMC8878631

Abstract Article PDF–2.2M

Select item 887819810.

CXCR2 Receptor: Regulation of Expression, Signal Transduction, and Involvement in Cancer

Jan Korbecki, Patrycja Kupnicka, Mikołaj Chlubek, Jarosław Gorący, Izabela Gutowska, Irena Baranowska-Bosiacka

Int J Mol Sci. 2022 Feb; 23(4): 2168. Published online 2022 Feb 16. doi: 10.3390/ijms23042168

PMCID:: PMC8878198

Abstract Article PDF–1.8M

Select item 880687711.

Effect of interleukin-8 receptor B (IL8RB) rs1126579 C>T variation on the risk to cancer

Lihong Zhu, Bowen Tang, Ze Zhang, Shuzhang Wei, Zhiwei Lv, Yujuan Zhang, Minlie Yang

Bioengineered. 2021; 12(1): 3367–3384. Published online 2021 Jul 8. doi: 10.1080/21655979.2021.1947442

PMCID:: PMC8806877

Abstract Article PDF–3.8M

Select item 867433212.

Early senescence and production of senescence-associated cytokines are major determinants of radioresistance in head-and-neck squamous cell carcinoma

Ulrike Schoetz, Diana Klein, Julia Hess, Seyd Shnayien, Steffen Spoerl, Michael Orth, Samet Mutlu, Roman Hennel, Anja Sieber, Ute Ganswindt, Benedikt Luka, Andreas R. Thomsen, Kristian Unger, Verena Jendrossek, Horst Zitzelsberger, Nils Blüthgen, Claus Belka, Steffen Unkel, Bertram Klinger, Kirsten Lauber

Cell Death Dis. 2021 Dec; 12(12): 1162. Published online 2021 Dec 15. doi: 10.1038/s41419-021-04454-5

PMCID:: PMC8674332

Abstract Article PDF–4.9M

Select item 862618413.

Prognostic and Immunological Significance of CXCR2 in Ovarian Cancer: A Promising Target for Survival Outcome and Immunotherapeutic Response Assessment

Haizhou Ji, Mi Ren, Tongyu Liu, Yang Sun

Dis Markers. 2021; 2021: 5350232. Published online 2021 Nov 19. doi: 10.1155/2021/5350232

PMCID:: PMC8626184

Abstract Article PDF–5.5M

Select item 853179414.

Impacts of Chemokine (C-X-C Motif) Receptor 2 C1208T Polymorphism on Cancer Susceptibility

Jing Zhou, Hao Wu, Quan-Xin Su, Xiao-Kai Shi, Bo-Wen Tang, Cui-Ping Zhao, Hai Wang, Xiao-Ping Chen

J Immunol Res. 2021; 2021: 8727924. Published online 2021 Oct 14. doi: 10.1155/2021/8727924

PMCID:: PMC8531794

Abstract Article PDF–3.6M

Select item 820289915.

Inhibition of CXCR2 plays a pivotal role in re-sensitizing ovarian cancer to cisplatin treatment

Taciane Barbosa Henriques, Diandra Zipinotti dos Santos, Isabella dos Santos Guimarães, Nayara Gusmão Tessarollo, Paulo Cilas Morais Lyra-Junior, Patricia Mesquita, Diana Pádua, Ana Luisa Amaral, Bruno Cavadas, Luisa Pereira, Ian Victor Silva, Raquel Maria da Silva Graça Almeida, Leticia Batista Azevedo Rangel

Aging (Albany NY) 2021 May 31; 13(10): 13405–13420. Published online 2021 May 26. doi: 10.18632/aging.203074

PMCID:: PMC8202899

Abstract Article PDF–1.3M

Select item 778579516.

Distinguishing Sepsis From Infection by Neutrophil Dysfunction: A Promising Role of CXCR2 Surface Level

Chutima Seree-aphinan, Polathep Vichitkunakorn, Raphatphorn Navakanitworakul, Bodin Khwannimit

Front Immunol. 2020; 11: 608696. Published online 2020 Dec 23. doi: 10.3389/fimmu.2020.608696

PMCID:: PMC7785795

Abstract Article PDF–1.9M

Select item 775779117.

Therapeutic blockade of CXCR2 rapidly clears inflammation in arthritis and atopic dermatitis models: demonstration with surrogate and humanized antibodies

Md Jahangir Alam, Liang Xie, Caroline Ang, Farnaz Fahimi, Stephen B. Willingham, Andrew J. Kueh, Marco J. Herold, Charles R. Mackay, Remy Robert

MAbs. 2020 Jan-Dec; 12(1): 1856460. Published online 2020 Dec 21. doi: 10.1080/19420862.2020.1856460

PMCID:: PMC7757791

Abstract Article PDF–11M

Select item 699418118.

The role of CXCR2 in acute inflammatory responses and its antagonists as anti-inflammatory therapeutics

Xiaoyu Zhang, Rongxia Guo, Hiroto Kambara, Fengxia Ma, Hongbo R. Luo

Curr Opin Hematol. Author manuscript; available in PMC 2020 Jan 31.

Published in final edited form as: Curr Opin Hematol. 2019 Jan; 26(1): 28–33. doi: 10.1097/MOH.0000000000000476

PMCID:: PMC6994181

Abstract Article PDF–316K

Select item 697878219.

CXCR2 Signaling and Remyelination in Preclinical Models of Demyelination

Dominic D. Skinner, Thomas E. Lane

DNA Cell Biol. January 2020; 39(1): 3–7. Published online 2020 Jan 8. doi: 10.1089/dna.2019.5182

PMCID:: PMC6978782

Abstract Article PDF–442K

Select item 671479820.

Disrupted CXCR2 Signaling in Oligodendroglia Lineage Cells Enhances Myelin Repair in a Viral Model of Multiple Sclerosis

Brett S. Marro, Dominic D. Skinner, Yuting Cheng, Jonathan J. Grist, Laura L. Dickey, Emily Eckman, Colleen Stone, Liping Liu, Richard M. Ransohoff, Thomas E. Lane

J Virol. 2019 Sep 15; 93(18): e00240-19. Prepublished online 2019 Jun 26. Published online 2019 Aug 28. doi: 10.1128/JVI.00240-19