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Select item 87915011.

Activation of the ubiquitin-proteasome system contributes to oculopharyngeal muscular dystrophy through muscle atrophy

Cécile Ribot, Cédric Soler, Aymeric Chartier, Sandy Al Hayek, Rima Naït-Saïdi, Nicolas Barbezier, Olivier Coux, Martine Simonelig

PLoS Genet. 2022 Jan; 18(1): e1010015. Published online 2022 Jan 13. doi: 10.1371/journal.pgen.1010015

PMCID:: PMC8791501

Abstract Article PDF–3.6M

Select item 102345492.

Asynchronous transcription and translation of neurotransmitter-related genes characterize the initial stages of neuronal maturation in Drosophila

Graça S. Marques, José Teles-Reis, Nikolaos Konstantinides, Patrícia H. Brito, Catarina C. F. Homem

PLoS Biol. 2023 May; 21(5): e3002115. Published online 2023 May 19. doi: 10.1371/journal.pbio.3002115

PMCID:: PMC10234549

Abstract Article PDF–3.4M

Select item 38777433.

Integrating protein-protein interaction networks with phenotypes reveals signs of interactions

Arunachalam Vinayagam, Jonathan Zirin, Charles Roesel, Yanhui Hu, Bahar Yilmazel, Anastasia A. Samsonova, Ralph A. Neumüller, Stephanie E. Mohr, Norbert Perrimon

Nat Methods. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: Nat Methods. 2014 Jan; 11(1): 94–99. Published online 2013 Nov 17. doi: 10.1038/nmeth.2733

PMCID:: PMC3877743

Abstract Article PDF–1.6M

Select item 25752094.

Varicose: a MAGUK required for the maturation and function of Drosophila septate junctions

Katherine E Moyer, J Roger Jacobs

BMC Dev Biol. 2008; 8: 99. Published online 2008 Oct 10. doi: 10.1186/1471-213X-8-99

PMCID:: PMC2575209

Abstract Article PDF–5.6M

Select item 86725795.

A cis-regulatory-directed pipeline for the identification of genes involved in cardiac development and disease

Hieu T. Nim, Louis Dang, Harshini Thiyagarajah, Daniel Bakopoulos, Michael See, Natalie Charitakis, Tennille Sibbritt, Michael P. Eichenlaub, Stuart K. Archer, Nicolas Fossat, Richard E. Burke, Patrick P. L. Tam, Coral G. Warr, Travis K. Johnson, Mirana Ramialison

Genome Biol. 2021; 22: 335. Published online 2021 Dec 15. doi: 10.1186/s13059-021-02539-0

PMCID:: PMC8672579

Abstract Article PDF–2.6M

Select item 46427096.

Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi

Benjamin E. Housden, Alexander J. Valvezan, Colleen Kelley, Richelle Sopko, Yanhui Hu, Charles Roesel, Shuailiang Lin, Michael Buckner, Rong Tao, Bahar Yilmazel, Stephanie E. Mohr, Brendan D. Manning, Norbert Perrimon

Sci Signal. Author manuscript; available in PMC 2016 Mar 8.

Published in final edited form as: Sci Signal. 2015; 8(393): rs9. Published online 2015 Sep 8. doi: 10.1126/scisignal.aab3729

PMCID:: PMC4642709

Abstract Article PDF–959K

Select item 87273537.

Proteasome α6 Subunit Negatively Regulates the JAK/STAT Pathway and Blood Cell Activation in Drosophila melanogaster

Mirva Järvelä-Stölting, Laura Vesala, Matthew K. Maasdorp, Joanna Ciantar, Mika Rämet, Susanna Valanne

Front Immunol. 2021; 12: 729631. Published online 2021 Dec 22. doi: 10.3389/fimmu.2021.729631

PMCID:: PMC8727353

Abstract Article PDF–4.4M

Select item 37008148.

Impaired proteasomal degradation enhances autophagy via hypoxia signaling in Drosophila

Péter Lőw, Ágnes Varga, Karolina Pircs, Péter Nagy, Zsuzsanna Szatmári, Miklós Sass, Gábor Juhász

BMC Cell Biol. 2013; 14: 29. Published online 2013 Jun 25. doi: 10.1186/1471-2121-14-29

PMCID:: PMC3700814

Abstract Article PDF–2.3M

Select item 26882859.

PDGF/VEGF signaling controls cell size in Drosophila

David Sims, Peter Duchek, Buzz Baum

Genome Biol. 2009; 10(2): R20. Published online 2009 Feb 12. doi: 10.1186/gb-2009-10-2-r20

PMCID:: PMC2688285

Abstract Article PDF–6.2M

Select item 571445610.

Dendritic Cytoskeletal Architecture Is Modulated by Combinatorial Transcriptional Regulation in Drosophila melanogaster

Ravi Das, Shatabdi Bhattacharjee, Atit A. Patel, Jenna M. Harris, Surajit Bhattacharya, Jamin M. Letcher, Sarah G. Clark, Sumit Nanda, Eswar Prasad R. Iyer, Giorgio A. Ascoli, Daniel N. Cox

Genetics. 2017 Dec; 207(4): 1401–1421. Published online 2017 Oct 12. doi: 10.1534/genetics.117.300393

PMCID:: PMC5714456

Abstract Article PDF–4.4M

Select item 778725811.

Prolonged Exposure to Microgravity Reduces Cardiac Contractility and Initiates Remodeling in Drosophila

Stanley Walls, Soda Diop, Ryan Birse, Lisa Elmen, Zhuohui Gan, Sreehari Kalvakuri, Santiago Pineda, Curran Reddy, Erika Taylor, Bosco Trinh, Georg Vogler, Rachel Zarndt, Andrew McCulloch, Peter Lee, Sharmila Bhattacharya, Rolf Bodmer, Karen Ocorr

Cell Rep. Author manuscript; available in PMC 2021 Jan 6.

Published in final edited form as: Cell Rep. 2020 Dec 8; 33(10): 108445. Published online 2020 Nov 25. doi: 10.1016/j.celrep.2020.108445

PMCID:: PMC7787258

Abstract Article PDF–1.5M

Select item 453277612.

The Hippo pathway promotes cell survival in response to chemical stress

F Di Cara, T M Maile, B D Parsons, A Magico, S Basu, N Tapon, K King-Jones

Cell Death Differ. 2015 Sep; 22(9): 1526–1539. Published online 2015 Mar 13. doi: 10.1038/cdd.2015.10

PMCID:: PMC4532776

Abstract Article PDF–2.5M

Select item 146175813.

Map position and expression of the genes in the 38 region of Drosophila.

H Butler, S Levine, X Wang, S Bonyadi, G Fu, P Lasko, B Suter, R Doerig

Genetics. 2001 Aug; 158(4): 1597–1614. doi: 10.1093/genetics/158.4.1597

PMCID:: PMC1461758

Summary PDF–776K

Select item 114061914.

Identification and Characterization of a Drosophila Proteasome Regulatory Network

Josefin Lundgren, Patrick Masson, Zahra Mirzaei, Patrick Young

Mol Cell Biol. 2005 Jun; 25(11): 4662–4675. doi: 10.1128/MCB.25.11.4662-4675.2005

PMCID:: PMC1140619

Abstract Article PDF–820K

Select item 303661815.

False negative rates in Drosophila cell-based RNAi screens: a case study

Matthew Booker, Anastasia A Samsonova, Young Kwon, Ian Flockhart, Stephanie E Mohr, Norbert Perrimon

BMC Genomics. 2011; 12: 50. Published online 2011 Jan 20. doi: 10.1186/1471-2164-12-50

PMCID:: PMC3036618

Abstract Article PDF–1005K

Select item 639850116.

SOD1 activity threshold and TOR signalling modulate VAP(P58S) aggregation via reactive oxygen species-induced proteasomal degradation in a Drosophila model of amyotrophic lateral sclerosis

Kriti Chaplot, Lokesh Pimpale, Balaji Ramalingam, Senthilkumar Deivasigamani, Siddhesh S. Kamat, Girish S. Ratnaparkhi

Dis Model Mech. 2019 Feb 1; 12(2): dmm033803. Published online 2019 Feb 7. doi: 10.1242/dmm.033803

PMCID:: PMC6398501

Abstract Article

Select item 426505517.

Screen for mitochondrial DNA copy number maintenance genes reveals essential role for ATP synthase

Atsushi Fukuoh, Giuseppe Cannino, Mike Gerards, Suzanne Buckley, Selena Kazancioglu, Filippo Scialo, Eero Lihavainen, Andre Ribeiro, Eric Dufour, Howard T Jacobs

Mol Syst Biol. 2014 Jun 25; 10(6): 734. Published online 2014 Jul 1. doi: 10.15252/msb.20145117