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Select item 44439481.

XRCC5 as a Risk Gene for Alcohol Dependence: Evidence from a Genome-Wide Gene-Set-Based Analysis and Follow-up Studies in Drosophila and Humans

Dilafruz Juraeva, Jens Treutlein, Henrike Scholz, Josef Frank, Franziska Degenhardt, Sven Cichon, Monika Ridinger, Manuel Mattheisen, Stephanie H Witt, Maren Lang, Wolfgang H Sommer, Per Hoffmann, Stefan Herms, Norbert Wodarz, Michael Soyka, Peter Zill, Wolfgang Maier, Elisabeth Jünger, Wolfgang Gaebel, Norbert Dahmen, Norbert Scherbaum, Christine Schmäl, Michael Steffens, Susanne Lucae, Marcus Ising, Michael N Smolka, Ulrich S Zimmermann, Bertram Müller-Myhsok, Markus M Nöthen, Karl Mann, Falk Kiefer, Rainer Spanagel, Benedikt Brors, Marcella Rietschel

Neuropsychopharmacology. 2015 Jan; 40(2): 361–371. Prepublished online 2014 Jul 18. Published online 2014 Aug 13. doi: 10.1038/npp.2014.178

PMCID:: PMC4443948

Abstract Article PDF–458K

Select item 66986612.

A Drosophila cell-free system that senses DNA breaks and triggers phosphorylation signalling

Lisa Harpprecht, Sandro Baldi, Tamas Schauer, Andreas Schmidt, Tanja Bange, Maria S Robles, Elisabeth Kremmer, Axel Imhof, Peter B Becker

Nucleic Acids Res. 2019 Aug 22; 47(14): 7444–7459. Published online 2019 May 31. doi: 10.1093/nar/gkz473

PMCID:: PMC6698661

Abstract Article PDF–4.3M

Select item 14497063.

The Ku Protein Complex Is Involved in Length Regulation of Drosophila Telomeres

Larisa Melnikova, Harald Biessmann, Pavel Georgiev

Genetics. 2005 May; 170(1): 221–235. doi: 10.1534/genetics.104.034538

PMCID:: PMC1449706

Abstract Article PDF–458K

Select item 4284454.

Interplay between Drosophila Bloom's syndrome helicase and Ku autoantigen during nonhomologous end joining repair of P element-induced DNA breaks

Bosun Min, Brian T. Weinert, Donald C. Rio

Proc Natl Acad Sci U S A. 2004 Jun 15; 101(24): 8906–8911. Published online 2004 Jun 7. doi: 10.1073/pnas.0403000101

PMCID:: PMC428445

Abstract Article PDF–571K

Select item 81072845.

ERR and dPECR Suggest a Link Between Neuroprotection and the Regulation of Ethanol Consumption Preference

Laura Velo Escarcena, Margarita Neufeld, Marcella Rietschel, Rainer Spanagel, Henrike Scholz

Front Psychiatry. 2021; 12: 655816. Published online 2021 Apr 26. doi: 10.3389/fpsyt.2021.655816

PMCID:: PMC8107284

Abstract Article PDF–1.7M

Select item 68845796.

Transcription elongation factor AFF2/FMR2 regulates expression of expanded GGGGCC repeat-containing C9ORF72 allele in ALS/FTD

Yeliz Yuva-Aydemir, Sandra Almeida, Gopinath Krishnan, Tania F. Gendron, Fen-Biao Gao

Nat Commun. 2019; 10: 5466. Published online 2019 Nov 29. doi: 10.1038/s41467-019-13477-8

PMCID:: PMC6884579

Abstract Article PDF–2.5M

Select item 37819677.

Clustering and Protein Dynamics of Drosophila melanogaster Telomeres

Natalia Wesolowska, Flavia L. Amariei, Yikang S. Rong

Genetics. 2013 Oct; 195(2): 381–391. doi: 10.1534/genetics.113.155408

PMCID:: PMC3781967

Abstract Article PDF–2.3M

Select item 78803788.

Evaluation of the geroprotective effects of withaferin A in Drosophila melanogaster

Liubov Koval, Nadezhda Zemskaya, Alexander Aliper, Alex Zhavoronkov, Alexey Moskalev

Aging (Albany NY) 2021 Jan 31; 13(2): 1817–1841. Published online 2021 Jan 26. doi: 10.18632/aging.202572

PMCID:: PMC7880378

Abstract Article PDF–2.0M

Select item 38270769.

Drosophila UTX Coordinates with p53 to Regulate ku80 Expression in Response to DNA Damage

Chengwan Zhang, Zehui Hong, Wencui Ma, Da Ma, Yuchen Qian, Wei Xie, Feng Tie, Ming Fang

PLoS One. 2013; 8(11): e78652. Published online 2013 Nov 12. doi: 10.1371/journal.pone.0078652

PMCID:: PMC3827076

Abstract Article PDF–1.6M

Select item 199251810.

Up-regulation of the Ku heterodimer in Drosophila testicular cyst cells

Alexander M. Boutanaev, Lyudmila M. Mikhaylova, Dmitry I. Nurminsky.

FEBS Lett. Author manuscript; available in PMC 2008 May 1.

Published in final edited form as: FEBS Lett. 2007 May 1; 581(9): 1707–1715. Published online 2007 Mar 30. doi: 10.1016/j.febslet.2007.03.042

PMCID:: PMC1992518

Abstract Article PDF–739K

Select item 460991211.

Lifespan and Stress Resistance in Drosophila with Overexpressed DNA Repair Genes

Mikhail Shaposhnikov, Ekaterina Proshkina, Lyubov Shilova, Alex Zhavoronkov, Alexey Moskalev

Sci Rep. 2015; 5: 15299. Published online 2015 Oct 19. doi: 10.1038/srep15299

PMCID:: PMC4609912

Abstract Article PDF–1.0M

Select item 602824912.

The Histone Demethylase KDM5 Is Essential for Larval Growth in Drosophila

Coralie Drelon, Helen M. Belalcazar, Julie Secombe

Genetics. 2018 Jul; 209(3): 773–787. Published online 2018 May 15. doi: 10.1534/genetics.118.301004

PMCID:: PMC6028249

Abstract Article PDF–2.0M

Select item 631732013.

Timely double-strand break repair and pathway choice in pericentromeric heterochromatin depend on the histone demethylase dKDM4A

Aniek Janssen, Serafin U. Colmenares, Timothy Lee, Gary H. Karpen

Genes Dev. 2019 Jan 1; 33(1-2): 103–115. doi: 10.1101/gad.317537.118

PMCID:: PMC6317320

Abstract Article PDF–2.1M

Select item 341714314.

Double-Strand Breaks in Heterochromatin Move Outside of a Dynamic HP1a Domain to Complete Recombinational Repair

Irene Chiolo, Aki Minoda, Serafin U. Colmenares, Aris Polyzos, Sylvain V. Costes, Gary H. Karpen

Cell. Author manuscript; available in PMC 2012 Aug 12.

Published in final edited form as: Cell. 2011 Mar 4; 144(5): 732–744. Published online 2011 Feb 25. doi: 10.1016/j.cell.2011.02.012

PMCID:: PMC3417143

Abstract Article PDF–3.1M

Select item 351214715.

Long-Term and Short-Term Evolutionary Impacts of Transposable Elements on Drosophila

Yuh Chwen G. Lee, Charles H. Langley

Genetics. 2012 Dec; 192(4): 1411–1432. doi: 10.1534/genetics.112.145714

PMCID:: PMC3512147

Abstract Article PDF–2.0M

Select item 827580716.

VCP maintains nuclear size by regulating the DNA damage-associated MDC1–p53–autophagy axis in Drosophila

Ya-Chu Chang, Yu-Xiang Peng, Bo-Hua Yu, Henry C. Chang, Pei-Shin Liang, Ting-Yi Huang, Chao-Jie Shih, Li-An Chu, Tzu-Kang Sang

Nat Commun. 2021; 12: 4258. Published online 2021 Jul 12. doi: 10.1038/s41467-021-24556-0

PMCID:: PMC8275807

Abstract Article PDF–5.6M

Select item 651102117.

Partial inhibition of the overactivated Ku80-dependent DNA repair pathway rescues neurodegeneration in C9ORF72-ALS/FTD

Rodrigo Lopez-Gonzalez, Dejun Yang, Mochtar Pribadi, Tanya S. Kim, Gopinath Krishnan, So Yoen Choi, Soojin Lee, Giovanni Coppola, Fen-Biao Gao

Proc Natl Acad Sci U S A. 2019 May 7; 116(19): 9628–9633. Published online 2019 Apr 24. doi: 10.1073/pnas.1901313116

PMCID:: PMC6511021

Abstract Article PDF–1.3M

Select item 290192018.

Epigenetic Blocking of an Enhancer Region Controls Irradiation-Induced Proapoptotic Gene Expression in Drosophila Embryos

Yanping Zhang, Nianwei Lin, Pamela M. Carroll, Gina Chan, Bo Guan, Hong Xiao, Bing Yao, Samuel S. Wu, Lei Zhou

Dev Cell. Author manuscript; available in PMC 2010 Jul 12.

Published in final edited form as: Dev Cell. 2008 Apr; 14(4): 481–493. doi: 10.1016/j.devcel.2008.01.018

PMCID:: PMC2901920

Abstract Article PDF–2.8M

Select item 218021419.

DNA Repair in Drosophila : Insights from the Drosophila Genome Sequence

Jeff J. Sekelsky, Michael H. Brodsky, Kenneth C. Burtis

J Cell Biol. 2000 Jul 24; 150(2): 31–36. doi: 10.1083/jcb.150.2.f31

PMCID:: PMC2180214

Article PDF–114K

Select item 788619320.

Kinetochore-independent mechanisms of sister chromosome separation

Hannah Vicars, Travis Karg, Brandt Warecki, Ian Bast, William Sullivan

PLoS Genet. 2021 Jan; 17(1): e1009304. Published online 2021 Jan 29. doi: 10.1371/journal.pgen.1009304

PMCID:: PMC7886193

Abstract Article PDF–2.8M

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