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Select item 55217351.

Phylogenetic Origin and Diversification of RNAi Pathway Genes in Insects

Daniel Dowling, Thomas Pauli, Alexander Donath, Karen Meusemann, Lars Podsiadlowski, Malte Petersen, Ralph S. Peters, Christoph Mayer, Shanlin Liu, Xin Zhou, Bernhard Misof, Oliver Niehuis

Genome Biol Evol. 2016 Dec; 8(12): 3784–3793. Published online 2016 Dec 24. doi: 10.1093/gbe/evw281

PMCID:: PMC5521735

Abstract Article PDF–637K

Select item 39620032.

The Human dsRNA binding protein PACT is unable to functionally substitute for the Drosophila dsRNA binding protein R2D2

Benjamin K Dickerman, Jocelyn A McDonald, Ganes C Sen

Version 2. F1000Res. 2013; 2: 220. Published online 2014 Mar 28. doi: 10.12688/f1000research.2-220.v2

PMCID:: PMC3962003

Abstract Article PDF–817K

Select item 21687903.

The p122 Subunit of Tobacco Mosaic Virus Replicase Is a Potent Silencing Suppressor and Compromises both Small Interfering RNA- and MicroRNA-Mediated Pathways

Tibor Csorba, Aurelie Bovi, Tamás Dalmay, József Burgyán

J Virol. 2007 Nov; 81(21): 11768–11780. Published online 2007 Aug 22. doi: 10.1128/JVI.01230-07

PMCID:: PMC2168790

Abstract Article PDF–1.7M

Select item 15248954.

Dicer-2 and R2D2 coordinately bind siRNA to promote assembly of the siRISC complexes

Xiang Liu, Feng Jiang, Savitha Kalidas, Dean Smith, Qinghua Liu

RNA. 2006 Aug; 12(8): 1514–1520. doi: 10.1261/rna.101606

PMCID:: PMC1524895

Abstract Article PDF–300K

Select item 15008635.

Small RNA binding is a common strategy to suppress RNA silencing by several viral suppressors

Lóránt Lakatos, Tibor Csorba, Vitantonio Pantaleo, Elisabeth J Chapman, James C Carrington, Yu-Ping Liu, Valerian V Dolja, Lourdes Fernández Calvino, Juan José López-Moya, József Burgyán

EMBO J. 2006 Jun 21; 25(12): 2768–2780. Published online 2006 May 25. doi: 10.1038/sj.emboj.7601164

PMCID:: PMC1500863

Abstract Article PDF–428K

Select item 104603996.

Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers

Ting Deng, Shichen Su, Xun Yuan, Jinqiu He, Ying Huang, Jinbiao Ma, Jia Wang

Nat Commun. 2023; 14: 5228. Published online 2023 Aug 26. doi: 10.1038/s41467-023-40919-1

PMCID:: PMC10460399

Abstract Article PDF–2.0M

Select item 93440237.

Optimized protocols for RNA-induced silencing complex assembly and cleavage in cultured Drosophila cells

Yajie Gao, Yuanxiang Zhu, Qinmiao Sun, Dahua Chen

STAR Protoc. 2022 Sep 16; 3(3): 101596. Published online 2022 Jul 31. doi: 10.1016/j.xpro.2022.101596

PMCID:: PMC9344023

Abstract Article PDF–3.3M

Select item 92791538.

Structure of the Dicer-2–R2D2 heterodimer bound to a small RNA duplex

Sonomi Yamaguchi, Masahiro Naganuma, Tomohiro Nishizawa, Tsukasa Kusakizako, Yukihide Tomari, Hiroshi Nishimasu, Osamu Nureki

Nature. 2022; 607(7918): 393–398. Published online 2022 Jun 29. doi: 10.1038/s41586-022-04790-2

PMCID:: PMC9279153

Abstract Article PDF–14M

Select item 86770309.

Coleopteran-specific StaufenC functions like Drosophila melanogaster Loquacious-PD in dsRNA processing

Kyungbo Kim, Jinmo Koo, June-Sun Yoon, Subba Reddy Palli

RNA Biol. 2021; 18(Suppl 1): 467–477. Published online 2021 Aug 11. doi: 10.1080/15476286.2021.1960687

PMCID:: PMC8677030

Abstract Article PDF–1.9M

Select item 565804210.

Overexpression and purification of Dicer and accessory proteins for biochemical and structural studies

Niladri K. Sinha, Brenda L. Bass

Methods. Author manuscript; available in PMC 2018 Aug 15.

Published in final edited form as: Methods. 2017 Aug 15; 126: 54–65. Published online 2017 Jul 16. doi: 10.1016/j.ymeth.2017.07.012

PMCID:: PMC5658042

Abstract Article PDF–822K

Select item 523879011.

Partial reconstitution of the RNAi response in human cells using Drosophila gene products

Edward M. Kennedy, Anand V.R. Kornepati, Hal P. Bogerd, Bryan R. Cullen

RNA. 2017 Feb; 23(2): 153–160. doi: 10.1261/rna.059345.116

PMCID:: PMC5238790

Abstract Article PDF–488K

Select item 389030012.

Transposon Defense by Endo-siRNAs, piRNAs and Somatic pilRNAs in Drosophila: Contributions of Loqs-PD and R2D2

Milijana Mirkovic-Hösle, Klaus Förstemann

PLoS One. 2014; 9(1): e84994. Published online 2014 Jan 13. doi: 10.1371/journal.pone.0084994

PMCID:: PMC3890300

Abstract Article PDF–872K

Select item 342667513.

The Small Interfering RNA Pathway Is Not Essential for Wolbachia-Mediated Antiviral Protection in Drosophila melanogaster

Lauren M. Hedges, Ryuichi Yamada, Scott L. O'Neill, Karyn N. Johnson

Appl Environ Microbiol. 2012 Sep; 78(18): 6773–6776. doi: 10.1128/AEM.01650-12

PMCID:: PMC3426675

Abstract Article PDF–458K

Select item 298421314.

RNAi-mediated immunity provides strong protection against the negative-strand RNA vesicular stomatitis virus in Drosophila

Stefanie Mueller, Valérie Gausson, Nicolas Vodovar, Safia Deddouche, Laurent Troxler, Jonathan Perot, Sébastien Pfeffer, Jules A. Hoffmann, Maria-Carla Saleh, Jean-Luc Imler

Proc Natl Acad Sci U S A. 2010 Nov 9; 107(45): 19390–19395. Published online 2010 Oct 26. doi: 10.1073/pnas.1014378107

PMCID:: PMC2984213

Abstract Article PDF–1002K

Select item 292419615.

Functional analysis of dicer-2 missense mutations in the siRNA pathway of Drosophila

Do Hwan Lim, Jung Kim, Sanguk Kim, Richard W. Carthew, Young Sik Lee

Biochem Biophys Res Commun. Author manuscript; available in PMC 2010 Aug 19.

Published in final edited form as: Biochem Biophys Res Commun. 2008 Jul 4; 371(3): 525–530. Published online 2008 Apr 30. doi: 10.1016/j.bbrc.2008.04.118

PMCID:: PMC2924196

Abstract Article PDF–1.3M

Select item 150909716.

RNA Interference Directs Innate Immunity Against Viruses in Adult Drosophila

Xiao-Hong Wang, Roghiyh Aliyari, Wan-Xiang Li, Hong-Wei Li, Kevin Kim, Richard Carthew, Peter Atkinson, Shou-Wei Ding

Science. Author manuscript; available in PMC 2006 Oct 21.

Published in final edited form as: Science. 2006 Apr 21; 312(5772): 452–454. Published online 2006 Mar 23. doi: 10.1126/science.1125694

PMCID:: PMC1509097

Abstract Article PDF–871K

Select item 547314717.

The C-terminal dsRNA-binding domain of Drosophila Dicer-2 is crucial for efficient and high-fidelity production of siRNA and loading of siRNA to Argonaute2

Suresh K. Kandasamy, Li Zhu, Ryuya Fukunaga

RNA. 2017 Jul; 23(7): 1139–1153. doi: 10.1261/rna.059915.116

PMCID:: PMC5473147

Abstract Article PDF–754K

Select item 402464518.

Derivation and characterization of Dicer- and microRNA-deficient human cells

Hal P. Bogerd, Adam W. Whisnant, Edward M. Kennedy, Omar Flores, Bryan R. Cullen

RNA. 2014 Jun; 20(6): 923–937. doi: 10.1261/rna.044545.114

PMCID:: PMC4024645

Abstract Article PDF–424K

Select item 375703719.

Functional Specialization of the Small Interfering RNA Pathway in Response to Virus Infection

Joao Trindade Marques, Ji-Ping Wang, Xiaohong Wang, Karla Pollyanna Vieira de Oliveira, Catherine Gao, Eric Roberto Guimaraes Rocha Aguiar, Nadereh Jafari, Richard W. Carthew

PLoS Pathog. 2013 Aug; 9(8): e1003579. Published online 2013 Aug 29. doi: 10.1371/journal.ppat.1003579