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Select item 111263781.

Dyssegmental dysplasia Rolland–Desbuquois type is caused by pathogenic variants in HSPG2 - a founder haplotype shared in five patients

Paniz Farshadyeganeh, Takahiro Yamada, Hirofumi Ohashi, Gen Nishimura, Hiroki Fujita, Yuriko Oishi, Misa Nunode, Shuku Ishikawa, Jun Murotsuki, Yuri Yamashita, Shiro Ikegawa, Tomoo Ogi, Eri Arikawa-Hirasawa, Kinji Ohno

J Hum Genet. 2024; 69(6): 235–244. Published online 2024 Feb 29. doi: 10.1038/s10038-024-01229-6

PMCID:: PMC11126378

Abstract Article PDF–2.1M

Select item 79625402.

Perlecan in Pericellular Mechanosensory Cell-Matrix Communication, Extracellular Matrix Stabilisation and Mechanoregulation of Load-Bearing Connective Tissues

Farshid Guilak, Anthony J. Hayes, James Melrose

Int J Mol Sci. 2021 Mar; 22(5): 2716. Published online 2021 Mar 8. doi: 10.3390/ijms22052716

PMCID:: PMC7962540

Abstract Article PDF–6.8M

Select item 73270063.

HSPG2 overexpression independently predicts poor survival in patients with acute myeloid leukemia

Xiaojia Zhou, Simin Liang, Qian Zhan, Li Yang, Jianxiang Chi, Li Wang

Cell Death Dis. 2020 Jun; 11(6): 492. Published online 2020 Jun 30. doi: 10.1038/s41419-020-2694-7

PMCID:: PMC7327006

Abstract Article PDF–1.0M

Select item 67137914.

Discovery of HSPG2 (Perlecan) as a Therapeutic Target in Triple Negative Breast Cancer

Stephen Kalscheuer, Vidhi Khanna, Hyunjoon Kim, Sihan Li, Deepali Sachdev, Arthur DeCarlo, Da Yang, Jayanth Panyam

Sci Rep. 2019; 9: 12492. Published online 2019 Aug 28. doi: 10.1038/s41598-019-48993-6

PMCID:: PMC6713791

Abstract Article PDF–6.9M

Select item 63344175.

Rare variant of HSPG2 is not involved in the development of adolescent idiopathic scoliosis: evidence from a large-scale replication study

Chao Xia, Leilei Xu, Bingchuan Xue, Fei Sheng, Yong Qiu, Zezhang Zhu

BMC Musculoskelet Disord. 2019; 20: 24. Published online 2019 Jan 15. doi: 10.1186/s12891-019-2402-x

PMCID:: PMC6334417

Abstract Article PDF–546K

Select item 60144736.

Dyssegmental dysplasia, Silverman‐Handmaker type: A challenging antenatal diagnosis in a dizygotic twin pregnancy

Shuaa Basalom, Yannis Trakadis, Roberta Shear, Michel E. Azouz, Isabelle De Bie

Mol Genet Genomic Med. 2018 May; 6(3): 452–456. Published online 2018 Mar 11. doi: 10.1002/mgg3.379

PMCID:: PMC6014473

Abstract Article PDF–603K

Select item 50304677.

The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling

Megan S. Lord, Christine Y. Chuang, James Melrose, Michael J. Davies, Renato V. Iozzo, John M. Whitelock

Matrix Biol. Author manuscript; available in PMC 2016 Sep 21.

Published in final edited form as: Matrix Biol. 2014 Apr; 35: 112–122. Published online 2014 Feb 6. doi: 10.1016/j.matbio.2014.01.016

PMCID:: PMC5030467

Abstract Article PDF–1.2M

Select item 50166648.

Endorepellin-evoked Autophagy Contributes to Angiostasis

Atul Goyal, Maria A. Gubbiotti, Daphney R. Chery, Lin Han, Renato V. Iozzo

J Biol Chem. 2016 Sep 9; 291(37): 19245–19256. Published online 2016 Jul 19. doi: 10.1074/jbc.M116.740266

PMCID:: PMC5016664

Abstract Article PDF–3.5M

Select item 49258269.

Perlecan expression influences the keratin 15‐positive cell population fate in the epidermis of aging skin

Morgan Dos Santos, Anna Michopoulou, Valérie André‐Frei, Sophie Boulesteix, Christine Guicher, Guila Dayan, John Whitelock, Odile Damour, Patricia Rousselle

Aging (Albany NY) 2016 Apr; 8(4): 751–768. Published online 2016 Mar 17. doi: 10.18632/aging.100928

PMCID:: PMC4925826

Abstract Article PDF–4.0M

Select item 480835810.

Single Molecule Force Measurements of Perlecan/HSPG2: A Key Component of the Osteocyte Pericellular Matrix

Sithara S. Wijeratne, Jerahme R. Martinez, Brian J. Grindel, Eric W. Frey, Jingqiang Li, Liyun Wang, Mary C. Farach-Carson, Ching-Hwa Kiang

Matrix Biol. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Matrix Biol. 2016 Mar; 50: 27–38. Published online 2015 Nov 4. doi: 10.1016/j.matbio.2015.11.001

PMCID:: PMC4808358

Abstract Article PDF–1.8M

Select item 471713311.

What maintains the high intra-follicular estradiol concentration in pre-ovulatory follicles?

Yaakov Bentov, Andrea Jurisicova, Shlomit Kenigsberg, Robert F. Casper

J Assist Reprod Genet. 2016 Jan; 33(1): 85–94. Published online 2015 Nov 9. doi: 10.1007/s10815-015-0612-1

PMCID:: PMC4717133

Abstract Article PDF–824K

Select item 432102512.

Exome Sequencing Identifies a Rare HSPG2 Variant Associated with Familial Idiopathic Scoliosis

Erin E. Baschal, Cambria I. Wethey, Kandice Swindle, Robin M. Baschal, Katherine Gowan, Nelson L.S. Tang, David M. Alvarado, Gabe E. Haller, Matthew B. Dobbs, Matthew R.G. Taylor, Christina A. Gurnett, Kenneth L. Jones, Nancy H. Miller

G3 (Bethesda) 2015 Feb; 5(2): 167–174. Published online 2014 Dec 12. doi: 10.1534/g3.114.015669

PMCID:: PMC4321025

Abstract Article PDF–863K

Select item 409197713.

Transcriptional Activation by NFκB Increases Perlecan/HSPG2 Expression in the Desmoplastic Prostate Tumor Microenvironment

Curtis R. Warren, Brian J. Grindel, Lewis Francis, Daniel D. Carson, Mary C. Farach-Carson

J Cell Biochem. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: J Cell Biochem. 2014 Jul; 115(7): 1322–1333. doi: 10.1002/jcb.24788

Correction in:: J Cell Biochem. 2016 Nov; 117(11): 2669.

PMCID:: PMC4091977

Abstract Article PDF–3.1M

Select item 393899714.

Border Patrol: Insights into the Unique Role of Perlecan/Heparan Sulfate Proteoglycan2 at Cell and Tissue Borders

Mary C. Farach-Carson, Curtis R. Warren, Daniel A. Harrington, Daniel D. Carson

Matrix Biol. Author manuscript; available in PMC 2015 Feb 1.

Published in final edited form as: Matrix Biol. 2014 Feb; 34: 64–79. Published online 2013 Aug 31. doi: 10.1016/j.matbio.2013.08.004

PMCID:: PMC3938997

Abstract Article PDF–1.9M

Select item 380863715.

Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity

Helena C. Christianson, Katrin J. Svensson, Toin H. van Kuppevelt, Jin-Ping Li, Mattias Belting

Proc Natl Acad Sci U S A. 2013 Oct 22; 110(43): 17380–17385. Published online 2013 Oct 7. doi: 10.1073/pnas.1304266110

PMCID:: PMC3808637

Abstract Article PDF–1.1M

Select item 370068916.

Association of Urinary Laminin G-Like 3 and Free K Light Chains with Disease Activity and Histological Injury in IgA Nephropathy

Maria Teresa Rocchetti, Massimo Papale, Anna Maria d’Apollo, Ida Valentina Suriano, Anna Maria Di Palma, Grazia Vocino, Eustacchio Montemurno, Leonarda Varraso, Giuseppe Grandaliano, Salvatore Di Paolo, Loreto Gesualdo

Clin J Am Soc Nephrol. 2013 Jul 3; 8(7): 1115–1125. Published online 2013 Apr 18. doi: 10.2215/CJN.05950612