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Select item 95452421.

Vitamin B6 rescues insulin resistance and glucose‐induced DNA damage caused by reduced activity of Drosophila PI3K

Elisa Mascolo, Francesco Liguori, Chiara Merigliano, Ludovica Schiano, Eleonora Gnocchini, Eleonora Pilesi, Cinzia Volonté, Martino L. Di Salvo, Roberto Contestabile, Angela Tramonti, Fiammetta Vernì

J Cell Physiol. 2022 Sep; 237(9): 3578–3586. Published online 2022 Jun 9. doi: 10.1002/jcp.30812

PMCID:: PMC9545242

Abstract Article PDF–1.8M

Select item 44491192.

The Unique Non-Catalytic C-Terminus of P37delta-PI3K Adds Proliferative Properties In Vitro and In Vivo

Katarina Ejeskär, Oscar Vickes, Arunakar Kuchipudi, Yvonne Wettergren, Anne Uv, Victoria Rotter Sopasakis

PLoS One. 2015; 10(5): e0127497. Published online 2015 May 29. doi: 10.1371/journal.pone.0127497

PMCID:: PMC4449119

Abstract Article PDF–4.0M

Select item 36018333.

Development of diet-induced insulin resistance in adult Drosophila melanogaster

Siti Nur Sarah Morris, Claire Coogan, Khalil Chamseddin, Sun Ok Fernandez-Kim, Santharam Kolli, Jeffrey N. Keller, Johannes H. Bauer

Biochim Biophys Acta. Author manuscript; available in PMC 2013 Aug 1.

Published in final edited form as: Biochim Biophys Acta. 2012 Aug; 1822(8): 1230–1237. Published online 2012 Apr 20. doi: 10.1016/j.bbadis.2012.04.012

PMCID:: PMC3601833

Abstract Article PDF–2.8M

Select item 72826724.

Dilp-2–mediated PI3-kinase activation coordinates reactivation of quiescent neuroblasts with growth of their glial stem cell niche

Xin Yuan, Conor W. Sipe, Miyuki Suzawa, Michelle L. Bland, Sarah E. Siegrist

PLoS Biol. 2020 May; 18(5): e3000721. Published online 2020 May 28. doi: 10.1371/journal.pbio.3000721

Correction in:: PLoS Biol. 2021 Oct; 19(10): e3001438.

PMCID:: PMC7282672

Abstract Article PDF–4.8M

Select item 28724215.

PI3 kinase signaling is involved in Aβ-induced memory loss in Drosophila

Hsueh-Cheng Chiang, Lei Wang, Zuolei Xie, Alice Yau, Yi Zhong

Proc Natl Acad Sci U S A. 2010 Apr 13; 107(15): 7060–7065. Published online 2010 Mar 29. doi: 10.1073/pnas.0909314107

PMCID:: PMC2872421

Abstract Article PDF–669K

Select item 46490096.

S6 Kinase Reflects and Regulates Ethanol-Induced Sedation

Summer F. Acevedo, Raniero L. Peru y Colón de Portugal, Dante A. Gonzalez, Aylin R. Rodan, Adrian Rothenfluh

J Neurosci. 2015 Nov 18; 35(46): 15396–15402. doi: 10.1523/JNEUROSCI.1880-15.2015

PMCID:: PMC4649009

Abstract Article PDF–1.0M

Select item 84830197.

A PtdIns(3,4,5)P₃ dispersal switch engages cell ratcheting at specific cell surfaces

Hui Miao, Timothy E. Vanderleest, Rashmi Budhathoki, Dinah Loerke, J. Todd Blankenship

Dev Cell. Author manuscript; available in PMC 2022 Sep 27.

Published in final edited form as: Dev Cell. 2021 Sep 27; 56(18): 2579–2591.e4. Published online 2021 Sep 14. doi: 10.1016/j.devcel.2021.08.016

PMCID:: PMC8483019

Abstract Article PDF–3.4M

Select item 60637288.

Pooled genome-wide CRISPR screening for basal and context-specific fitness gene essentiality in Drosophila cells

Raghuvir Viswanatha, Zhongchi Li, Yanhui Hu, Norbert Perrimon

eLife. 2018; 7: e36333. Published online 2018 Jul 27. doi: 10.7554/eLife.36333

PMCID:: PMC6063728

Abstract Article PDF–3.1M

Select item 55764839.

Eyeless uncouples mushroom body neuroblast proliferation from dietary amino acids in Drosophila

Conor W Sipe, Sarah E Siegrist

eLife. 2017; 6: e26343. Published online 2017 Aug 9. doi: 10.7554/eLife.26343

PMCID:: PMC5576483

Abstract Article PDF–4.4M

Select item 45248310.

The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth.

S J Leevers, D Weinkove, L K MacDougall, E Hafen, M D Waterfield

EMBO J. 1996 Dec 2; 15(23): 6584–6594.

PMCID:: PMC452483

Summary Page Browse PDF–3.1M

Select item 621971911.

Spatial control of Draper receptor signaling initiates apoptotic cell engulfment

Adam P. Williamson, Ronald D. Vale

J Cell Biol. 2018 Nov 5; 217(11): 3977–3992. doi: 10.1083/jcb.201711175

PMCID:: PMC6219719

Abstract Article PDF–2.2M

Select item 31703612.

Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin

Sean Oldham, Jacques Montagne, Thomas Radimerski, George Thomas, Ernst Hafen

Genes Dev. 2000 Nov 1; 14(21): 2689–2694. doi: 10.1101/gad.845700

PMCID:: PMC317036

Abstract Article PDF–3.3M

Select item 540798013.

Anterograde transport of Rab4-associated vesicles regulates synapse organization in Drosophila

Swagata Dey, Gary Banker, Krishanu Ray

Cell Rep. Author manuscript; available in PMC 2017 Apr 28.

Published in final edited form as: Cell Rep. 2017 Mar 7; 18(10): 2452–2463. doi: 10.1016/j.celrep.2017.02.034

PMCID:: PMC5407980

Abstract Article PDF–1.7M

Select item 537434314.

Neuroblast niche position is controlled by Phosphoinositide 3-kinase-dependent DE-Cadherin adhesion

Susan E. Doyle, Matthew C. Pahl, Karsten H. Siller, Lindsay Ardiff, Sarah E. Siegrist

Development. 2017 Mar 1; 144(5): 820–829. doi: 10.1242/dev.136713

PMCID:: PMC5374343

Abstract Article

Select item 309429015.

Genome-wide screen for modifiers of Parkinson's disease genes in Drosophila

Caroline Fernandes, Yong Rao

Mol Brain. 2011; 4: 17. Published online 2011 Apr 19. doi: 10.1186/1756-6606-4-17

PMCID:: PMC3094290

Abstract Article PDF–913K

Select item 225493816.

DIET CONTROLS NORMAL AND TUMOROUS GERMLINE STEM CELLS VIA INSULIN-DEPENDENT AND -INDEPENDENT MECHANISMS IN DROSOPHILA

Hwei-Jan Hsu, Leesa LaFever, Daniela Drummond-Barbosa

Dev Biol. Author manuscript; available in PMC 2009 Jan 15.

Published in final edited form as: Dev Biol. 2008 Jan 15; 313(2): 700–712. Published online 2007 Nov 17. doi: 10.1016/j.ydbio.2007.11.006

PMCID:: PMC2254938

Abstract Article PDF–3.1M

Select item 857029617.

Toll receptors remodel epithelia by directing planar polarized Src and PI3K activity

Masako Tamada, Jay Shi, Kia S. Bourdot, Sara Supriyatno, Karl H. Palmquist, Omar L. Gutierrez-Ruiz, Jennifer A. Zallen

Dev Cell. Author manuscript; available in PMC 2022 Jun 7.

Published in final edited form as: Dev Cell. 2021 Jun 7; 56(11): 1589–1602.e9. Published online 2021 Apr 30. doi: 10.1016/j.devcel.2021.04.012

PMCID:: PMC8570296

Abstract Article PDF–3.3M

Select item 382402118.

Architects in neural circuit design: Glia control neuron numbers and connectivity

Megan M. Corty, Marc R. Freeman

J Cell Biol. 2013 Nov 11; 203(3): 395–405. doi: 10.1083/jcb.201306099

PMCID:: PMC3824021

Abstract Article PDF–1.7M

Select item 308748919.

Nutrition-Responsive Glia Control Exit of Neural Stem Cells from Quiescence

James M. Chell, Andrea H. Brand

Cell. 2010 Dec 23; 143(7): 1161–1173. doi: 10.1016/j.cell.2010.12.007

PMCID:: PMC3087489

Abstract Article

Select item 890673320.

Nutrients and pheromones promote insulin release to inhibit courtship drive

Liwei Zhang, Xuan Guo, Wei Zhang

Sci Adv. 2022 Mar; 8(10): eabl6121. Published online 2022 Mar 9. doi: 10.1126/sciadv.abl6121

PMCID:: PMC8906733

Abstract Article PDF–915K

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