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Select item 49706941.

De novo loss-of-function mutations in WAC cause a recognizable intellectual disability syndrome and learning deficits in Drosophila

Dorien Lugtenberg, Margot R F Reijnders, Michaela Fenckova, Emilia K Bijlsma, Raphael Bernier, Bregje W M van Bon, Eric Smeets, Anneke T Vulto-van Silfhout, Danielle Bosch, Evan E Eichler, Heather C Mefford, Gemma L Carvill, Ernie M H F Bongers, Janneke HM Schuurs-Hoeijmakers, Claudia A Ruivenkamp, Gijs W E Santen, Arn M J M van den Maagdenberg, Cacha M P C D Peeters-Scholte, Sabine Kuenen, Patrik Verstreken, Rolph Pfundt, Helger G Yntema, Petra F de Vries, Joris A Veltman, Alexander Hoischen, Christian Gilissen, Bert B A de Vries, Annette Schenck, Tjitske Kleefstra, Lisenka E L M Vissers

Eur J Hum Genet. 2016 Aug; 24(8): 1145–1153. Published online 2016 Jan 13. doi: 10.1038/ejhg.2015.282

PMCID:: PMC4970694

Abstract Article PDF–1.1M

Select item 47305482.

WAC regulates mTOR activity by acting as an adaptor for the TTT and Pontin/Reptin complexes

Gabriela David-Morrison, Zhen Xu, Yan-Ning Rui, Wu-Lin Charng, Manish Jaiswal, Shinya Yamamoto, Bo Xiong, Ke Zhang, Hector Sandoval, Lita Duraine, Zhongyuan Zuo, Sheng Zhang, Hugo J. Bellen

Dev Cell. Author manuscript; available in PMC 2017 Jan 25.

Published in final edited form as: Dev Cell. 2016 Jan 25; 36(2): 139–151. doi: 10.1016/j.devcel.2015.12.019

PMCID:: PMC4730548

Abstract Article PDF–3.5M

Select item 84424453.

The gut-microbiota-brain axis in autism: what Drosophila models can offer?

Safa Salim, Ayesha Banu, Amira Alwa, Swetha B. M. Gowda, Farhan Mohammad

J Neurodev Disord. 2021; 13: 37. Published online 2021 Sep 15. doi: 10.1186/s11689-021-09378-x

PMCID:: PMC8442445

Abstract Article PDF–1.9M

Select item 43303754.

Enhancer modeling uncovers transcriptional signatures of individual cardiac cell states in Drosophila

Brian W. Busser, Julian Haimovich, Di Huang, Ivan Ovcharenko, Alan M. Michelson

Nucleic Acids Res. 2015 Feb 18; 43(3): 1726–1739. Published online 2015 Jan 21. doi: 10.1093/nar/gkv011

PMCID:: PMC4330375

Abstract Article PDF–13M

Select item 23749985.

Genomic mapping of Suppressor of Hairy-wing binding sites in Drosophila

Boris Adryan, Gertrud Woerfel, Ian Birch-Machin, Shan Gao, Marie Quick, Lisa Meadows, Steven Russell, Robert White

Genome Biol. 2007; 8(8): R167. Published online 2007 Aug 16. doi: 10.1186/gb-2007-8-8-r167

PMCID:: PMC2374998

Abstract Article PDF–1.5M

Select item 69450426.

A Genetic Screen for Genes That Impact Peroxisomes in Drosophila Identifies Candidate Genes for Human Disease

Hillary K. Graves, Sharayu Jangam, Kai Li Tan, Antonella Pignata, Elaine S. Seto, Shinya Yamamoto, Michael F. Wangler

G3 (Bethesda) 2020 Jan; 10(1): 69–77. Published online 2019 Nov 25. doi: 10.1534/g3.119.400803

PMCID:: PMC6945042

Abstract Article PDF–2.2M

Select item 5454947.

A computational and experimental approach to validating annotations and gene predictions in the Drosophila melanogaster genome

Mark Yandell, Adina M. Bailey, Sima Misra, ShengQiang Shu, Colin Wiel, Martha Evans-Holm, Susan E. Celniker, Gerald M. Rubin

Proc Natl Acad Sci U S A. 2005 Feb 1; 102(5): 1566–1571. Published online 2005 Jan 24. doi: 10.1073/pnas.0409421102

PMCID:: PMC545494

Abstract Article PDF–332K

Select item 36794478.

The Genetic Makeup of the Drosophila piRNA Pathway

Dominik Handler, Katharina Meixner, Manfred Pizka, Kathrin Lauss, Christopher Schmied, Franz Sebastian Gruber, Julius Brennecke

Mol Cell. 2013 Jun 6; 50(5): 762–777. doi: 10.1016/j.molcel.2013.04.031

PMCID:: PMC3679447

Abstract Article

Select item 97134319.

Transcriptome analysis of FOXO-dependent hypoxia gene expression identifies Hipk as a regulator of low oxygen tolerance in Drosophila

Kate Ding, Elizabeth C Barretto, Michael Johnston, Byoungchun Lee, Marco Gallo, Savraj S Grewal

G3 (Bethesda) 2022 Dec; 12(12): jkac263. Published online 2022 Oct 6. doi: 10.1093/g3journal/jkac263

PMCID:: PMC9713431

Abstract Article PDF–1.0M

Select item 456802510.

Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions

Albert J. Erives

Dev Genes Evol. 2015; 225(5): 259–273. Published online 2015 Jul 15. doi: 10.1007/s00427-015-0508-1

PMCID:: PMC4568025

Abstract Article PDF–2.8M

Select item 439805011.

The Genetic Basis for Variation in Olfactory Behavior in Drosophila melanogaster

Gunjan H. Arya, Michael M. Magwire, Wen Huang, Yazmin L. Serrano-Negron, Trudy F.C. Mackay, Robert R.H. Anholt

Chem Senses. 2015 May; 40(4): 233–243. Published online 2015 Feb 15. doi: 10.1093/chemse/bjv001

PMCID:: PMC4398050

Abstract Article PDF–8.9M

Select item 473800512.

Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes

Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Bezginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, W. Brent Derry, Elisabeth R. Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Data Brief. 2016 Mar; 6: 715–721. Published online 2015 Dec 12. doi: 10.1016/j.dib.2015.11.062

PMCID:: PMC4738005

Abstract Article PDF–205K

Select item 866448613.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 696157814.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 427152715.

Phylostratigraphic Bias Creates Spurious Patterns of Genome Evolution

Bryan A. Moyers, Jianzhi Zhang

Mol Biol Evol. 2015 Jan 1; 32(1): 258–267. Published online 2014 Oct 13. doi: 10.1093/molbev/msu286

Correction in:: Mol Biol Evol. 2016 Nov; 33(11): 3031.

PMCID:: PMC4271527

Abstract Article PDF–618K

Select item 285522116.

A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function

G. Gregory Neely, Keiji Kuba, Anthony Cammarato, Kazuya Isobe, Sabine Amann, Liyong Zhang, Mitsushige Murata, Lisa Elmén, Vaijayanti Gupta, Suchir Arora, Rinku Sarangi, Debasis Dan, Susumu Fujisawa, Takako Usami, Cui-ping Xia, Alex C. Keene, Nakissa N. Alayari, Hiroyuki Yamakawa, Ulrich Elling, Christian Berger, Maria Novatchkova, Rubina Koglgruber, Keiichi Fukuda, Hiroshi Nishina, Mitsuaki Isobe, J. Andrew Pospisilik, Yumiko Imai, Arne Pfeufer, Andrew A Hicks, Peter P. Pramstaller, Sai Subramaniam, Akinori Kimura, Karen Ocorr, Rolf Bodmer, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Apr 2.

Published in final edited form as: Cell. 2010 Apr 2; 141(1): 142–153. doi: 10.1016/j.cell.2010.02.023

PMCID:: PMC2855221

Abstract Article PDF–5.3M

Select item 304044117.

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionary-conserved pain gene

G. Gregory Neely, Andreas Hess, Michael Costigan, Alex C. Keene, Spyros Goulas, Michiel Langeslag, Robert S Griffin, Inna Belfer, Feng Dai, Shad Smith, Luda Diatchenko, Vaijayanti Gupta, Cui-ping Xia, Sabina Amann, Silke Kreitz, Cornelia Heindl-Erdmann, Susanne Wolz, Cindy V. Ly, Suchir Arora, Rinku Sarangi, Debasis Dan, Maria Novatchkova, Mark Rosenzweig, Dustin Gibson, Darwin Truong, Daniel Schramek, Tamara Zoranovic, Shane J. F. Cronin, Belinda Angjeli, Kay Brune, Georg Dietzl, William Maixner, Arabella Meixner, Winston Thomas, J. Andrew Pospisilik, Mattias Alenius, Michaela Kress, Sai Subramaniam, Paul A. Garrity, Hugo J. Bellen, Clifford J. Woolf, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Nov 12.

Published in final edited form as: Cell. 2010 Nov 12; 143(4): 628–638. doi: 10.1016/j.cell.2010.09.047

PMCID:: PMC3040441

Abstract Article PDF–2.0M

Select item 353067718.

High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression

Philippe Batut, Alexander Dobin, Charles Plessy, Piero Carninci, Thomas R. Gingeras

Genome Res. 2013 Jan; 23(1): 169–180. doi: 10.1101/gr.139618.112

PMCID:: PMC3530677

Abstract Article PDF–1.5M

Select item 570780519.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900220.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

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