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Select item 109455581.

Balance of activity during a critical period tunes a developing network

Iain Hunter, Bramwell Coulson, Tom Pettini, Jacob J Davies, Jill Parkin, Matthias Landgraf, Richard A Baines

eLife. 2024; 12: RP91599. Published online 2024 Jan 9. doi: 10.7554/eLife.91599

PMCID:: PMC10945558

Abstract Article PDF–2.6M

Select item 101855152.

Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models

Luis Filipe Costa-Machado, Esther Garcia-Dominguez, Rebecca L. McIntyre, Jose Luis Lopez-Aceituno, Álvaro Ballesteros-Gonzalez, Andrea Tapia-Gonzalez, David Fabregat-Safont, Tobias Eisenberg, Jesús Gomez, Adrian Plaza, Aranzazu Sierra-Ramirez, Manuel Perez, David Villanueva-Bermejo, Tiziana Fornari, María Isabel Loza, Gonzalo Herradon, Sebastian J. Hofer, Christoph Magnes, Frank Madeo, Janet S. Duerr, Oscar J. Pozo, Maximo-Ibo Galindo, Isabel del Pino, Riekelt H. Houtkooper, Diego Megias, Jose Viña, Mari Carmen Gomez-Cabrera, Pablo J. Fernandez-Marcos

Nat Commun. 2023; 14: 2779. Published online 2023 May 15. doi: 10.1038/s41467-023-38410-y

PMCID:: PMC10185515

Abstract Article PDF–3.1M

Select item 100123873.

Fly seizure EEG: field potential activity in the Drosophila brain

Atulya Iyengar, Chun-Fang Wu

J Neurogenet. Author manuscript; available in PMC 2023 Mar 14.

Published in final edited form as: J Neurogenet. 2021 Sep; 35(3): 295–305. Published online 2021 Jul 18. doi: 10.1080/01677063.2021.1950714

PMCID:: PMC10012387

Abstract Article PDF–1.6M

Select item 99894074.

Attenuation of Seizures, Cognitive Deficits, and Brain Histopathology by Phytochemicals of Imperata cylindrica (L.) P. Beauv (Poaceae) in Acute and Chronic Mutant Drosophila melanogaster Epilepsy Models

Fred Ssempijja, Samuel Sunday Dare, Edmund E. M. Bukenya, Keneth Iceland Kasozi, Ritah Kenganzi, Edgar Mario Fernandez, Marta Vicente-Crespo

J Evid Based Integr Med. 2023; 28: 2515690X231160191. Published online 2023 Mar 3. doi: 10.1177/2515690X231160191

PMCID:: PMC9989407

Abstract Article PDF–2.9M

Select item 98841085.

Nonspiking Interneurons in the Drosophila Antennal Lobe Exhibit Spatially Restricted Activity

Jonathan E. Schenk, Quentin Gaudry

eNeuro. 2023 Jan; 10(1): ENEURO.0109-22.2022. Prepublished online 2023 Jan 17. Published online 2023 Jan 24. doi: 10.1523/ENEURO.0109-22.2022

PMCID:: PMC9884108

Abstract Article PDF–3.4M

Select item 87558026.

Reversing insecticide resistance with allelic-drive in Drosophila melanogaster

Bhagyashree Kaduskar, Raja Babu Singh Kushwah, Ankush Auradkar, Annabel Guichard, Menglin Li, Jared B. Bennett, Alison Henrique Ferreira Julio, John M. Marshall, Craig Montell, Ethan Bier

Nat Commun. 2022; 13: 291. Published online 2022 Jan 12. doi: 10.1038/s41467-021-27654-1

PMCID:: PMC8755802

Abstract Article PDF–2.8M

Select item 86193387.

Generation and Characterization of the Drosophila melanogaster paralytic Gene Knock-Out as a Model for Dravet Syndrome

Andrea Tapia, Carlo N. Giachello, Martina Palomino-Schätzlein, Richard A. Baines, Máximo Ibo Galindo

Life (Basel) 2021 Nov; 11(11): 1261. Published online 2021 Nov 18. doi: 10.3390/life11111261

PMCID:: PMC8619338

Abstract Article PDF–8.6M

Select item 84749138.

Assessing the anti-resistance potential of public health vaporizer formulations and insecticide mixtures with pyrethroids using transgenic Drosophila lines

Hang Ngoc Bao Luong, Arunas Damijonaitis, Ralf Nauen, John Vontas, Sebastian Horstmann

Parasit Vectors. 2021; 14: 495. Published online 2021 Sep 26. doi: 10.1186/s13071-021-04997-8

PMCID:: PMC8474913

Abstract Article PDF–793K

Select item 84549219.

Seizure Phenotype and Underlying Cellular Defects in Drosophila Knock-In Models of DS (R1648C) and GEFS+ (R1648H) SCN1A Epilepsy

Alexa Joanna Roemmich, Thy Vu, Tamas Lukacsovich, Charlesice Hawkins, Soleil S. Schutte, Diane K. O’Dowd

eNeuro. 2021 Sep-Oct; 8(5): ENEURO.0002-21.2021. Prepublished online 2021 Sep 2. Published online 2021 Sep 20. doi: 10.1523/ENEURO.0002-21.2021

PMCID:: PMC8454921

Abstract Article PDF–2.9M

Select item 728735810.

‘What I cannot create, I do not understand’: functionally validated synergism of metabolic and target site insecticide resistance

George-Rafael Samantsidis, Rafaela Panteleri, Shane Denecke, Stella Kounadi, Iason Christou, Ralf Nauen, Vassilis Douris, John Vontas

Proc Biol Sci. 2020 May 27; 287(1927): 20200838. Published online 2020 May 27. doi: 10.1098/rspb.2020.0838

PMCID:: PMC7287358

Abstract Article PDF–949K

Select item 692367011.

Functional Genomics of Epilepsy and Associated Neurodevelopmental Disorders Using Simple Animal Models: From Genes, Molecules to Brain Networks

Richard Rosch, Dominic R. W. Burrows, Laura B. Jones, Colin H. Peters, Peter Ruben, Éric Samarut

Front Cell Neurosci. 2019; 13: 556. Published online 2019 Dec 13. doi: 10.3389/fncel.2019.00556

PMCID:: PMC6923670

Abstract Article PDF–550K

Select item 674490712.

Pore-modulating toxins exploit inherent slow inactivation to block K⁺ channels

Izhar Karbat, Hagit Altman-Gueta, Shachar Fine, Tibor Szanto, Shelly Hamer-Rogotner, Orly Dym, Felix Frolow, Dalia Gordon, Gyorgy Panyi, Michael Gurevitz, Eitan Reuveny

Proc Natl Acad Sci U S A. 2019 Sep 10; 116(37): 18700–18709. Published online 2019 Aug 23. doi: 10.1073/pnas.1908903116

PMCID:: PMC6744907

Abstract Article PDF–2.0M

Select item 657824713.

Sodium current density correlates with expression of specific alternatively spliced sodium channel mRNAs in single neurons

DK O'Dowd, JR Gee, MA Smith

J Neurosci. 1995 May 1; 15(5): 4005–4012. doi: 10.1523/JNEUROSCI.15-05-04005.1995

PMCID:: PMC6578247

Abstract PDF–2.0M

Select item 481906614.

Model systems for studying cellular mechanisms of SCN1A-related epilepsy

Soleil S. Schutte, Ryan J. Schutte, Eden V. Barragan, Diane K. O'Dowd

J Neurophysiol. 2016 Apr 1; 115(4): 1755–1766. Published online 2016 Feb 3. doi: 10.1152/jn.00824.2015

PMCID:: PMC4819066

Abstract Article

Select item 474929815.

Calcium Imaging of Neuronal Activity in Drosophila Can Identify Anticonvulsive Compounds

Anne K. Streit, Yuen Ngan Fan, Laura Masullo, Richard A. Baines

PLoS One. 2016; 11(2): e0148461. Published online 2016 Feb 10. doi: 10.1371/journal.pone.0148461

PMCID:: PMC4749298

Abstract Article PDF–1.2M

Select item 465190516.

Inappropriate Neural Activity during a Sensitive Period in Embryogenesis Results in Persistent Seizure-like Behavior

Carlo N.G. Giachello, Richard A. Baines

Curr Biol. 2015 Nov 16; 25(22): 2964–2968. doi: 10.1016/j.cub.2015.09.040

PMCID:: PMC4651905

Abstract Article

Select item 448234017.

Sequence variations at I260 and A1731 contribute to persistent currents in Drosophila sodium channels

Rong Gao, Yuzhe Du, Lingxin Wang, Yoshiko Nomura, Gul Satar, Dalia Gordon, Michael Gurevitz, Alan L. Goldin, Ke Dong

Neuroscience. Author manuscript; available in PMC 2015 Jun 26.

Published in final edited form as: Neuroscience. 2014 May 30; 268: 297–308. Published online 2014 Mar 21. doi: 10.1016/j.neuroscience.2014.03.028

PMCID:: PMC4482340

Abstract Article PDF–1.7M

Select item 443318118.

Distal Spike Initiation Zone Location Estimation by Morphological Simulation of Ionic Current Filtering Demonstrated in a Novel Model of an Identified Drosophila Motoneuron

Cengiz Günay, Fred H. Sieling, Logesh Dharmar, Wei-Hsiang Lin, Verena Wolfram, Richard Marley, Richard A. Baines, Astrid A. Prinz

PLoS Comput Biol. 2015 May; 11(5): e1004189. Published online 2015 May 15. doi: 10.1371/journal.pcbi.1004189

PMCID:: PMC4433181

Abstract Article PDF–3.7M

Select item 430991319.

Regulation of membrane excitability: a convergence on voltage-gated sodium conductance

Wei-Hsiang Lin, Richard A. Baines

Mol Neurobiol. 2015; 51(1): 57–67. Published online 2014 Mar 29. doi: 10.1007/s12035-014-8674-0

PMCID:: PMC4309913

Abstract Article PDF–878K

Select item 412274220.

Knock-in model of Dravet syndrome reveals a constitutive and conditional reduction in sodium current

Ryan J. Schutte, Soleil S. Schutte, Jacqueline Algara, Eden V. Barragan, Jeff Gilligan, Cynthia Staber, Yiannis A. Savva, Martin A. Smith, Robert Reenan, Diane K. O'Dowd

J Neurophysiol. 2014 Aug 15; 112(4): 903–912. Published online 2014 May 7. doi: 10.1152/jn.00135.2014

PMCID:: PMC4122742

Abstract Article

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