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Select item 108232321.

Trametinib ameliorates aging-associated gut pathology in Drosophila females by reducing Pol III activity in intestinal stem cells

Enric Ureña, Bowen Xu, Jennifer C. Regan, Magda L. Atilano, Lucy J. Minkley, Danny Filer, Yu-Xuan Lu, Ekin Bolukbasi, Mobina Khericha, Nazif Alic, Linda Partridge

Proc Natl Acad Sci U S A. 2024 Jan 23; 121(4): e2311313121. Published online 2024 Jan 19. doi: 10.1073/pnas.2311313121

PMCID:: PMC10823232

Abstract Article PDF–814K

Select item 87863272.

RNA polymerase II is recruited to DNA double-strand breaks for dilncRNA transcription in Drosophila

Romy Böttcher, Ines Schmidts, Volker Nitschko, Petar Duric, Klaus Förstemann

RNA Biol. 2022; 19(1): 68–77. Published online 2021 Dec 29. doi: 10.1080/15476286.2021.2014694

PMCID:: PMC8786327

Abstract Article PDF–2.4M

Select item 70133793.

Partial Inhibition of RNA Polymerase I Promotes Animal Health and Longevity

Guillermo Martínez Corrales, Danny Filer, Katharina C. Wenz, Abbie Rogan, George Phillips, Mengjia Li, Yodit Feseha, Susan J. Broughton, Nazif Alic

Cell Rep. 2020 Feb 11; 30(6): 1661–1669.e4. Published online 2020 Feb 11. doi: 10.1016/j.celrep.2020.01.017

PMCID:: PMC7013379

Abstract Article

Select item 57325704.

RNA polymerase III limits longevity downstream of TORC1

Danny Filer, Maximillian A. Thompson, Vakil Takhaveev, Adam J. Dobson, Ilektra Kotronaki, James W.M. Green, Matthias Heinemann, Jennifer M.A. Tullet, Nazif Alic

Nature. Author manuscript; available in PMC 2018 May 29.

Published in final edited form as: Nature. 2017 Dec 14; 552(7684): 263–267. Published online 2017 Nov 29. doi: 10.1038/nature25007

PMCID:: PMC5732570

Abstract Article PDF–4.6M

Select item 77042585.

In silico identification of Drosophila melanogaster genes encoding RNA polymerase subunits

Steven J Marygold, Nazif Alic, David S Gilmour, Savraj S Grewal

MicroPubl Biol. 2020; 2020: 10.17912/micropub.biology.000320. Published online 2020 Oct 20. doi: 10.17912/micropub.biology.000320

PMCID:: PMC7704258

Article PDF–416K

Select item 35383456.

Transcriptional Networks Controlling the Cell Cycle

Martin Bonke, Mikko Turunen, Maria Sokolova, Anna Vähärautio, Teemu Kivioja, Minna Taipale, Mikael Björklund, Jussi Taipale

G3 (Bethesda) 2013 Jan; 3(1): 75–90. Published online 2013 Jan 1. doi: 10.1534/g3.112.004283

PMCID:: PMC3538345

Abstract Article PDF–4.0M

Select item 53521457.

The genetic basis for variation in resistance to infection in the Drosophila melanogaster genetic reference panel

Jonathan B. Wang, Hsiao-Ling Lu, Raymond J. St. Leger

PLoS Pathog. 2017 Mar; 13(3): e1006260. Published online 2017 Mar 3. doi: 10.1371/journal.ppat.1006260

PMCID:: PMC5352145

Abstract Article PDF–2.9M

Select item 47881168.

Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet

Ibrahim Ömer Çiçek, Samir Karaca, Marko Brankatschk, Suzanne Eaton, Henning Urlaub, Halyna R. Shcherbata

Genetics. 2016 Mar; 202(3): 1167–1183. Published online 2016 Jan 22. doi: 10.1534/genetics.115.185371

PMCID:: PMC4788116

Abstract Article PDF–4.7M

Select item 47380059.

Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes

Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Bezginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, W. Brent Derry, Elisabeth R. Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Data Brief. 2016 Mar; 6: 715–721. Published online 2015 Dec 12. doi: 10.1016/j.dib.2015.11.062

PMCID:: PMC4738005

Abstract Article PDF–205K

Select item 866448610.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 488965811.

mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster

Gildas Lepennetier, Francesco Catania

G3 (Bethesda) 2016 Jun; 6(6): 1617–1626. Published online 2016 Mar 28. doi: 10.1534/g3.116.029231

PMCID:: PMC4889658

Abstract Article PDF–1.5M

Select item 285522112.

A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function

G. Gregory Neely, Keiji Kuba, Anthony Cammarato, Kazuya Isobe, Sabine Amann, Liyong Zhang, Mitsushige Murata, Lisa Elmén, Vaijayanti Gupta, Suchir Arora, Rinku Sarangi, Debasis Dan, Susumu Fujisawa, Takako Usami, Cui-ping Xia, Alex C. Keene, Nakissa N. Alayari, Hiroyuki Yamakawa, Ulrich Elling, Christian Berger, Maria Novatchkova, Rubina Koglgruber, Keiichi Fukuda, Hiroshi Nishina, Mitsuaki Isobe, J. Andrew Pospisilik, Yumiko Imai, Arne Pfeufer, Andrew A Hicks, Peter P. Pramstaller, Sai Subramaniam, Akinori Kimura, Karen Ocorr, Rolf Bodmer, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Apr 2.

Published in final edited form as: Cell. 2010 Apr 2; 141(1): 142–153. doi: 10.1016/j.cell.2010.02.023

PMCID:: PMC2855221

Abstract Article PDF–5.3M

Select item 304044113.

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionary-conserved pain gene

G. Gregory Neely, Andreas Hess, Michael Costigan, Alex C. Keene, Spyros Goulas, Michiel Langeslag, Robert S Griffin, Inna Belfer, Feng Dai, Shad Smith, Luda Diatchenko, Vaijayanti Gupta, Cui-ping Xia, Sabina Amann, Silke Kreitz, Cornelia Heindl-Erdmann, Susanne Wolz, Cindy V. Ly, Suchir Arora, Rinku Sarangi, Debasis Dan, Maria Novatchkova, Mark Rosenzweig, Dustin Gibson, Darwin Truong, Daniel Schramek, Tamara Zoranovic, Shane J. F. Cronin, Belinda Angjeli, Kay Brune, Georg Dietzl, William Maixner, Arabella Meixner, Winston Thomas, J. Andrew Pospisilik, Mattias Alenius, Michaela Kress, Sai Subramaniam, Paul A. Garrity, Hugo J. Bellen, Clifford J. Woolf, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Nov 12.

Published in final edited form as: Cell. 2010 Nov 12; 143(4): 628–638. doi: 10.1016/j.cell.2010.09.047

PMCID:: PMC3040441

Abstract Article PDF–2.0M

Select item 353067714.

High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression

Philippe Batut, Alexander Dobin, Charles Plessy, Piero Carninci, Thomas R. Gingeras

Genome Res. 2013 Jan; 23(1): 169–180. doi: 10.1101/gr.139618.112

PMCID:: PMC3530677

Abstract Article PDF–1.5M

Select item 570780515.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900216.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 435288717.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Abstract Article PDF–1022K

Select item 282505318.

Sequence Finishing and Mapping of Drosophila melanogaster Heterochromatin

Roger A. Hoskins, Joseph W. Carlson, Cameron Kennedy, David Acevedo, Martha Evans-Holm, Erwin Frise, Kenneth H. Wan, Soo Park, Maria Mendez-Lago, Fabrizio Rossi, Alfredo Villasante, Patrizio Dimitri, Gary H. Karpen, Susan E. Celniker

Science. Author manuscript; available in PMC 2010 Feb 19.

Published in final edited form as: Science. 2007 Jun 15; 316(5831): 1625–1628. doi: 10.1126/science.1139816

PMCID:: PMC2825053

Abstract Article PDF–858K

Select item 281928019.

The Release 5.1 Annotation of Drosophila melanogaster Heterochromatin

Christopher D. Smith, ShengQiang Shu, Christopher J. Mungall, Gary H. Karpen

Science. Author manuscript; available in PMC 2010 Feb 10.

Published in final edited form as: Science. 2007 Jun 15; 316(5831): 1586. doi: 10.1126/science.1139815

Correction in:: volume 317 on page 1325

PMCID:: PMC2819280

Abstract Article PDF–1.3M

Select item 118564820.

Combined Evidence Annotation of Transposable Elements in Genome Sequences

Hadi Quesneville, Casey M Bergman, Olivier Andrieu, Delphine Autard, Danielle Nouaud, Michael Ashburner, Dominique Anxolabehere

PLoS Comput Biol. 2005 Jul; 1(2): e22. Published online 2005 Jul 29. doi: 10.1371/journal.pcbi.0010022

PMCID:: PMC1185648

Abstract Article PDF–273K

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