PMC Links for Gene (Select 315427) - PMC

Select item 65801701.

Evidence for a role for Sestrin1 in mediating leucine-induced activation of mTORC1 in skeletal muscle

Dandan Xu, Kevin L. Shimkus, Holly A. Lacko, Lydia Kutzler, Leonard S. Jefferson, Scot R. Kimball

Am J Physiol Endocrinol Metab. 2019 May 1; 316(5): E817–E828. Published online 2019 Mar 5. doi: 10.1152/ajpendo.00522.2018

PMCID:: PMC6580170

Abstract Article

Select item 43750822.

Sestrin 3 Protein Enhances Hepatic Insulin Sensitivity by Direct Activation of the mTORC2-Akt Signaling

Rongya Tao, Xiwen Xiong, Suthat Liangpunsakul, X. Charlie Dong

Diabetes. 2015 Apr; 64(4): 1211–1223. Published online 2014 Nov 4. doi: 10.2337/db14-0539

PMCID:: PMC4375082

Abstract Article PDF–2.1M

Select item 46980173.

Sestrin2 is a leucine sensor for the mTORC1 pathway

Rachel L. Wolfson, Lynne Chantranupong, Robert A. Saxton, Kuang Shen, Sonia M. Scaria, Jason R. Cantor, David M. Sabatini

Science. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Science. 2016 Jan 1; 351(6268): 43–48. Published online 2015 Oct 8. doi: 10.1126/science.aab2674

PMCID:: PMC4698017

Abstract Article PDF–1.4M

Select item 41813524.

Sestrins Function as Guanine Nucleotide Dissociation Inhibitors for Rag GTPases to Control mTORC1 Signaling

Min Peng, Na Yin, Ming O. Li

Cell. Author manuscript; available in PMC 2015 Sep 25.

Published in final edited form as: Cell. 2014 Sep 25; 159(1): 122–133. doi: 10.1016/j.cell.2014.08.038

PMCID:: PMC4181352

Abstract Article PDF–2.7M

Select item 36873655.

Maintenance of metabolic homeostasis by Sestrin 2 and 3

Jun Hee Lee, Andrei V. Budanov, Saswata Talukdar, Eek Joong Park, Hae Li Park, Hwan-Woo Park, Gautam Bandyopadhyay, Ning Li, Mariam Aghajan, Insook Jang, Amber M. Wolfe, Guy A. Perkins, Mark H. Ellisman, Ethan Bier, Miriam Scadeng, Marc Foretz, Benoit Viollet, Jerrold Olefsky, Michael Karin

Cell Metab. Author manuscript; available in PMC 2013 Jun 20.

Published in final edited form as: Cell Metab. 2012 Sep 5; 16(3): 311–321. doi: 10.1016/j.cmet.2012.08.004

PMCID:: PMC3687365

Abstract Article PDF–5.0M

Select item 42238666.

The Sestrins interact with GATOR2 to negatively regulate the amino acid sensing pathway upstream of mTORC1

Lynne Chantranupong, Rachel L. Wolfson, Jose M. Orozco, Robert A. Saxton, Sonia M. Scaria, Liron Bar-Peled, Eric Spooner, Marta Isasa, Steven P. Gygi, David M. Sabatini

Cell Rep. Author manuscript; available in PMC 2014 Nov 7.

Published in final edited form as: Cell Rep. 2014 Oct 9; 9(1): 1–8. Published online 2014 Sep 25. doi: 10.1016/j.celrep.2014.09.014

PMCID:: PMC4223866

Abstract Article PDF–616K

Select item 31780597.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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