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Select item 104506171.

The influence of angiopoietin-like protein 3 on macrophages polarization and its effect on the podocyte EMT in diabetic nephropathy

Yanli Ma, Yu Chen, Hong Xu, Ni Du

Front Immunol. 2023; 14: 1228399. Published online 2023 Aug 10. doi: 10.3389/fimmu.2023.1228399

PMCID:: PMC10450617

Abstract Article PDF–4.3M

Select item 90288602.

The Fibrinogen-like Domain of ANGPTL3 Facilitates Lipolysis in 3T3-L1 Cells by Activating the Intracellular Erk Pathway

Simone Bini, Valeria Pecce, Alessia Di Costanzo, Luca Polito, Ameneh Ghadiri, Ilenia Minicocci, Federica Tambaro, Stella Covino, Marcello Arca, Laura D’Erasmo

Biomolecules. 2022 Apr; 12(4): 585. Published online 2022 Apr 16. doi: 10.3390/biom12040585

PMCID:: PMC9028860

Abstract Article PDF–1.5M

Select item 79583513.

Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3

Min Qiu, Zachary Glass, Jinjin Chen, Mary Haas, Xin Jin, Xuewei Zhao, Xuehui Rui, Zhongfeng Ye, Yamin Li, Feng Zhang, Qiaobing Xu

Proc Natl Acad Sci U S A. 2021 Mar 9; 118(10): e2020401118. Published online 2021 Mar 1. doi: 10.1073/pnas.2020401118

PMCID:: PMC7958351

Abstract Article PDF–1.6M

Select item 65337584.

Angiopoietin-like-3 knockout protects against glomerulosclerosis in murine adriamycin-induced nephropathy by attenuating podocyte loss

Rufeng Dai, Haimei Liu, Xinli Han, Junchao Liu, Yihui Zhai, Jia Rao, Qian Shen, Hong Xu

BMC Nephrol. 2019; 20: 185. Published online 2019 May 24. doi: 10.1186/s12882-019-1383-1

PMCID:: PMC6533758

Abstract Article PDF–2.6M

Select item 45771795.

Hepatic ANGPTL3 regulates adipose tissue energy homeostasis

Yan Wang, Markey C. McNutt, Serena Banfi, Michael G. Levin, William L. Holland, Viktoria Gusarova, Jesper Gromada, Jonathan C. Cohen, Helen H. Hobbs

Proc Natl Acad Sci U S A. 2015 Sep 15; 112(37): 11630–11635. Published online 2015 Aug 24. doi: 10.1073/pnas.1515374112

PMCID:: PMC4577179

Abstract Article PDF–768K

Select item 41494696.

Angiopoietin-Like Protein 3 Promotes Preservation of Stemness during Ex Vivo Expansion of Murine Hematopoietic Stem Cells

Elnaz Farahbakhshian, Monique M. Verstegen, Trudi P. Visser, Sima Kheradmandkia, Dirk Geerts, Shazia Arshad, Noveen Riaz, Frank Grosveld, Niek P. van Til, Jules P. P. Meijerink

PLoS One. 2014; 9(8): e105642. Published online 2014 Aug 29. doi: 10.1371/journal.pone.0105642

PMCID:: PMC4149469

Abstract Article PDF–708K

Select item 30314767.

Angiopoietin-like protein 3 supports the activity of hematopoietic stem cells in the bone marrow niche

Junke Zheng, HoangDinh Huynh, Masato Umikawa, Robert Silvany, Cheng Cheng Zhang

Blood. 2011 Jan 13; 117(2): 470–479. Prepublished online 2010 Oct 19. doi: 10.1182/blood-2010-06-291716

PMCID:: PMC3031476

Abstract Article

Select item 109266218.

ANGPTL3 is a novel HDL component that regulates HDL function

Longyan Yang, Yan Wang, Yongsong Xu, Kun Li, Ruili Yin, Lijie Zhang, Di Wang, Lingling Wei, Jianan Lang, Yanan Cheng, Lu Wang, Jing Ke, Dong Zhao

J Transl Med. 2024; 22: 263. Published online 2024 Mar 10. doi: 10.1186/s12967-024-05032-x

PMCID:: PMC10926621

Abstract Article PDF–2.1M

Select item 102832749.

METTL3 regulates N6-methyladenosine modification of ANGPTL3 mRNA and potentiates malignant progression of stomach adenocarcinoma

Zhijin Zhang, Jun Fu, Yuhao Zhang, Xianju Qin, Yuexia Wang, Chungen Xing

BMC Gastroenterol. 2023; 23: 217. Published online 2023 Jun 21. doi: 10.1186/s12876-023-02844-x

PMCID:: PMC10283274

Abstract Article PDF–9.4M

Select item 899660410.

ANGPTL3 impacts proteinuria and hyperlipidemia in primary nephrotic syndrome

Fu Zhong, Shurao Liu, Yue Li, Guanyu Li, Ming Liu, Jingzhi Wang, Weijing Cui, Yanhong Suo, Xia Gao

Lipids Health Dis. 2022; 21: 38. Published online 2022 Apr 10. doi: 10.1186/s12944-022-01632-y

PMCID:: PMC8996604

Abstract Article PDF–2.0M

Select item 845605511.

Angiopoietin-like 3 inhibition of endothelial lipase is not modulated by angiopoietin-like 8

Kelli L. Sylvers-Davie, Ashley Segura-Roman, Alicia M. Salvi, Kylie J. Schache, Brandon S.J. Davies

J Lipid Res. 2021; 62: 100112. Published online 2021 Aug 27. doi: 10.1016/j.jlr.2021.100112

PMCID:: PMC8456055

Abstract Article PDF–2.1M

Select item 841739812.

Antisense oligonucleotide–mediated inhibition of angiopoietin-like protein 3 increases reverse cholesterol transport in mice

Thomas A. Bell, III, Mingxia Liu, Aaron J. Donner, Richard G. Lee, Adam E. Mullick, Rosanne M. Crooke

J Lipid Res. 2021; 62: 100101. Published online 2021 Aug 6. doi: 10.1016/j.jlr.2021.100101

PMCID:: PMC8417398

Abstract Article PDF–764K

Select item 746988713.

Angiopoietin-like protein 3 governs LDL-cholesterol levels through endothelial lipase-dependent VLDL clearance

Rene C. Adam, Ivory J. Mintah, Corey A. Alexa-Braun, Lisa M. Shihanian, Joseph S. Lee, Poulabi Banerjee, Sara C. Hamon, Hye In Kim, Jonathan C. Cohen, Helen H. Hobbs, Cristopher Van Hout, Jesper Gromada, Andrew J. Murphy, George D. Yancopoulos, Mark W. Sleeman, Viktoria Gusarova

J Lipid Res. 2020 Sep; 61(9): 1271–1286. Published online 2020 Jul 9. doi: 10.1194/jlr.RA120000888

PMCID:: PMC7469887

Abstract Article PDF–2.8M

Select item 576953114.

New insights into ANGPLT3 in controlling lipoprotein metabolism and risk of cardiovascular diseases

Xin Su, Dao-quan Peng

Lipids Health Dis. 2018; 17: 12. Published online 2018 Jan 15. doi: 10.1186/s12944-018-0659-y

PMCID:: PMC5769531

Abstract Article PDF–416K

Select item 468519615.

A lipasin/Angptl8 monoclonal antibody lowers mouse serum triglycerides involving increased postprandial activity of the cardiac lipoprotein lipase

Zhiyao Fu, Abdul B. Abou-Samra, Ren Zhang

Sci Rep. 2015; 5: 18502. Published online 2015 Dec 21. doi: 10.1038/srep18502

PMCID:: PMC4685196

Abstract Article PDF–1.1M

Select item 293462316.

Angiopoietin-like Protein 3 Inhibits Lipoprotein Lipase Activity through Enhancing Its Cleavage by Proprotein Convertases

Jun Liu, Huq Afroza, Daniel J. Rader, Weijun Jin

J Biol Chem. 2010 Sep 3; 285(36): 27561–27570. Published online 2010 Jun 26. doi: 10.1074/jbc.M110.144279

PMCID:: PMC2934623

Abstract Article PDF–1.8M

Select item 286788617.

Fetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells

Song Chou, Harvey F. Lodish

Proc Natl Acad Sci U S A. 2010 Apr 27; 107(17): 7799–7804. Published online 2010 Apr 12. doi: 10.1073/pnas.1003586107

PMCID:: PMC2867886

Abstract Article PDF–486K

Select item 256557518.

Hepatic Proprotein Convertases Modulate HDL Metabolism

Weijun Jin, Xun Wang, John S. Millar, Thomas Quertermous, George H. Rothblat, Jane M. Glick, Daniel J. Rader

Cell Metab. Author manuscript; available in PMC 2008 Oct 9.

Published in final edited form as: Cell Metab. 2007 Aug; 6(2): 129–136. doi: 10.1016/j.cmet.2007.07.009

PMCID:: PMC2565575

Abstract Article PDF–587K

Select item 154436019.

Ligand-activated PPARβ efficiently represses the induction of LXR-dependent promoter activity through competition with RXR

Kimihiko Matsusue, Aya Miyoshi, Shigeru Yamano, Frank J. Gonzalez

Mol Cell Endocrinol. Author manuscript; available in PMC 2006 Aug 15.

Published in final edited form as: Mol Cell Endocrinol. 2006 Aug 15; 256(1-2): 23–33. doi: 10.1016/j.mce.2006.05.005

PMCID:: PMC1544360

Abstract Article PDF–537K

Select item 575012720.

Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoproteins

Yu-Xin Xu, Valeska Redon, Haojie Yu, William Querbes, James Pirruccello, Abigail Liebow, Amy Deik, Kevin Trindade, Xiao Wang, Kiran Musunuru, Clary B. Clish, Chad Cowan, Kevin Fizgerald, Daniel Rader, Sekar Kathiresan

Atherosclerosis. Author manuscript; available in PMC 2019 Jan 1.

Published in final edited form as: Atherosclerosis. 2018 Jan; 268: 196–206. Published online 2017 Sep 21. doi: 10.1016/j.atherosclerosis.2017.08.031