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Select item 71122361.

Swimming motility of a gut bacterial symbiont promotes resistance to intestinal expulsion and enhances inflammation

Travis J. Wiles, Brandon H. Schlomann, Elena S. Wall, Reina Betancourt, Raghuveer Parthasarathy, Karen Guillemin

PLoS Biol. 2020 Mar; 18(3): e3000661. Published online 2020 Mar 20. doi: 10.1371/journal.pbio.3000661

PMCID:: PMC7112236

Abstract Article PDF–4.4M

Select item 97794382.

A New Transgenic Tool to Study the Ret Signaling Pathway in the Enteric Nervous System

Ashoka Bandla, Ellie Melancon, Charlotte R. Taylor, Ann E. Davidson, Judith S. Eisen, Julia Ganz

Int J Mol Sci. 2022 Dec; 23(24): 15667. Published online 2022 Dec 10. doi: 10.3390/ijms232415667

PMCID:: PMC9779438

Abstract Article PDF–2.9M

Select item 94993973.

Down-Regulation of Double C2 Domain Alpha Promotes the Formation of Hyperplastic Nerve Fibers in Aganglionic Segments of Hirschsprung’s Disease

Jun Xiao, Xinyao Meng, Ke Chen, Jing Wang, Luyao Wu, Yingjian Chen, Xiaosi Yu, Jiexiong Feng, Zhi Li

Int J Mol Sci. 2022 Sep; 23(18): 10204. Published online 2022 Sep 6. doi: 10.3390/ijms231810204

PMCID:: PMC9499397

Abstract Article PDF–3.4M

Select item 11570464.

Phenotype–genotype correlation in Hirschsprung disease is illuminated by comparative analysis of the RET protein sequence

Carl S. Kashuk, Eric A. Stone, Elizabeth A. Grice, Matthew E. Portnoy, Eric D. Green, Arend Sidow, Aravinda Chakravarti, Andrew S. McCallion

Proc Natl Acad Sci U S A. 2005 Jun 21; 102(25): 8949–8954. Published online 2005 Jun 13. doi: 10.1073/pnas.0503259102

PMCID:: PMC1157046

Abstract Article PDF–612K

Select item 103616615.

The interplay of common genetic variants NRG1 rs2439302 and RET rs2435357 increases the risk of developing Hirschsprung’s disease

Shuiqing Chi, Shuai Li, Guoqing Cao, Jialing Guo, Yunqiao Han, Yun Zhou, Xi Zhang, Yibo Li, Zhibin Luo, Xiangyang Li, Liying Rong, Mengxin Zhang, Linglu Li, Shaotao Tang

Front Cell Dev Biol. 2023; 11: 1184799. Published online 2023 Jul 7. doi: 10.3389/fcell.2023.1184799

PMCID:: PMC10361661

Abstract Article PDF–4.0M

Select item 96869966.

In toto imaging of early enteric nervous system development reveals that gut colonization is tied to proliferation downstream of Ret

Phillip A. Baker, Rodrigo Ibarra-García-Padilla, Akshaya Venkatesh, Eileen W. Singleton, Rosa. A. Uribe

Development. 2022 Nov 1; 149(21): dev200668. Published online 2022 Oct 31. doi: 10.1242/dev.200668

PMCID:: PMC9686996

Abstract Article

Select item 82663847.

A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing

Sarah E. Adams, Andrew G. Purkiss, Phillip P. Knowles, Andrea Nans, David C. Briggs, Annabel Borg, Christopher P. Earl, Kerry M. Goodman, Agata Nawrotek, Aaron J. Borg, Pauline B. McIntosh, Francesca M. Houghton, Svend Kjær, Neil Q. McDonald

Structure. 2021 Jul 1; 29(7): 694–708.e7. doi: 10.1016/j.str.2020.12.012

PMCID:: PMC8266384

Abstract Article

Select item 67182718.

Retrograde Ret signaling controls sensory pioneer axon outgrowth

Adam Tuttle, Catherine M Drerup, Molly Marra, Hillary McGraw, Alex V Nechiporuk

eLife. 2019; 8: e46092. Published online 2019 Sep 2. doi: 10.7554/eLife.46092

PMCID:: PMC6718271

Abstract Article PDF–5.9M

Select item 51301699.

A Novel Zebrafish ret Heterozygous Model of Hirschsprung Disease Identifies a Functional Role for mapk10 as a Modifier of Enteric Nervous System Phenotype Severity

Tiffany A. Heanue, Werend Boesmans, Donald M. Bell, Koichi Kawakami, Pieter Vanden Berghe, Vassilis Pachnis

PLoS Genet. 2016 Nov; 12(11): e1006439. Published online 2016 Nov 30. doi: 10.1371/journal.pgen.1006439

PMCID:: PMC5130169

Abstract Article PDF–2.4M

Select item 508871810.

Molecular fingerprinting delineates progenitor populations in the developing zebrafish enteric nervous system

Charlotte R. Taylor, William A. Montagne, Judith S. Eisen, Julia Ganz

Dev Dyn. Author manuscript; available in PMC 2017 Nov 1.

Published in final edited form as: Dev Dyn. 2016 Nov; 245(11): 1081–1096. Published online 2016 Sep 21. doi: 10.1002/dvdy.24438

PMCID:: PMC5088718

Abstract Article PDF–3.1M

Select item 496557311.

Exon Skipping in the RET Gene Encodes Novel Isoforms That Differentially Regulate RET Protein Signal Transduction

Nicole A. Gabreski, Janki K. Vaghasia, Silvia S. Novakova, Neil Q. McDonald, Brian A. Pierchala

J Biol Chem. 2016 Jul 29; 291(31): 16249–16262. Published online 2016 May 23. doi: 10.1074/jbc.M115.709675

PMCID:: PMC4965573

Abstract Article PDF–2.9M

Select item 432613812.

Depletion of the IKBKAP ortholog in zebrafish leads to hirschsprung disease-like phenotype

William Wai-Chun Cheng, Clara Sze-Man Tang, Hong-Sheng Gui, Man-Ting So, Vincent Chi-Hang Lui, Paul Kwong-Hang Tam, Maria-Mercè Garcia-Barcelo

World J Gastroenterol. 2015 Feb 21; 21(7): 2040–2046. Published online 2015 Feb 21. doi: 10.3748/wjg.v21.i7.2040

PMCID:: PMC4326138

Abstract Article PDF–1.0M

Select item 375934813.

Ahsa1 and Hsp90 activity confers more severe craniofacial phenotypes in a zebrafish model of hypoparathyroidism, sensorineural deafness and renal dysplasia (HDR)

Kelly Sheehan-Rooney, Mary E. Swartz, Feng Zhao, Dong Liu, Johann K. Eberhart

Dis Model Mech. 2013 Sep; 6(5): 1285–1291. Published online 2013 May 29. doi: 10.1242/dmm.011965

PMCID:: PMC3759348

Abstract Article

Select item 298421614.

Glial cell line-derived neurotrophic factor defines the path of developing and regenerating axons in the lateral line system of zebrafish

Kevin Schuster, Christine Dambly-Chaudière, Alain Ghysen

Proc Natl Acad Sci U S A. 2010 Nov 9; 107(45): 19531–19536. Published online 2010 Oct 25. doi: 10.1073/pnas.1002171107

PMCID:: PMC2984216

Abstract Article PDF–715K

Select item 599538715.

Binding of EphrinA5 to RET receptor tyrosine kinase: An in vitro study

Yixin Liu, Heidi Kaljunen, Ana Pavić, Tuulia Saarenpää, Juha P. Himanen, Dimitar B. Nikolov, Adrian Goldman

PLoS One. 2018; 13(6): e0198291. Published online 2018 Jun 11. doi: 10.1371/journal.pone.0198291

PMCID:: PMC5995387

Abstract Article PDF–3.5M

Select item 541519216.

Zebrafish GDNF and its co-receptor GFRα1 activate the human RET receptor and promote the survival of dopaminergic neurons in vitro

Tuulia Saarenpää, Konstantin Kogan, Yulia Sidorova, Arun Kumar Mahato, Igor Tascón, Heidi Kaljunen, Liying Yu, Jukka Kallijärvi, Jaana Jurvansuu, Mart Saarma, Adrian Goldman

PLoS One. 2017; 12(5): e0176166. Published online 2017 May 3. doi: 10.1371/journal.pone.0176166

PMCID:: PMC5415192

Abstract Article PDF–13M

Select item 437502617.

Mutations in RAD21 Disrupt Regulation of APOB in Patients with Chronic Intestinal Pseudo-obstruction

Elena Bonora, Francesca Bianco, Lina Cordeddu, Michael Bamshad, Ludmila Francescatto, Dustin Dowless, Vincenzo Stanghellini, Rosanna F. Cogliandro, Greger Lindberg, Zeynel Mungan, Kivanc Cefle, Tayfun Ozcelik, Sukru Palanduz, Sukru Ozturk, Asuman Gedikbasi, Alessandra Gori, Tommaso Pippucci, Claudio Graziano, Umberto Volta, Giacomo Caio, Giovanni Barbara, Mauro D'Amato, Marco Seri, Nicholas Katsanis, Giovanni Romeo, Roberto De Giorgio

Gastroenterology. Author manuscript; available in PMC 2016 Apr 1.

Published in final edited form as: Gastroenterology. 2015 Apr; 148(4): 771–782.e11. Published online 2015 Jan 6. doi: 10.1053/j.gastro.2014.12.034

PMCID:: PMC4375026

Abstract Article PDF–1.6M

Select item 261342018.

Collective Cell Migration Drives Morphogenesis of the Kidney Nephron

Aleksandr Vasilyev, Yan Liu, Sudha Mudumana, Steve Mangos, Pui-Ying Lam, Arindam Majumdar, Jinhua Zhao, Kar-Lai Poon, Igor Kondrychyn, Vladimir Korzh, Iain A Drummond

PLoS Biol. 2009 Jan; 7(1): e1000009. Published online 2009 Jan 6. doi: 10.1371/journal.pbio.1000009

PMCID:: PMC2613420

Abstract Article PDF–828K

Select item 572266019.

Retinoic acid temporally orchestrates colonization of the gut by vagal neural crest cells

Rosa A. Uribe, Stephanie S. Hong, Marianne E. Bronner

Dev Biol. Author manuscript; available in PMC 2019 Jan 1.

Published in final edited form as: Dev Biol. 2018 Jan 1; 433(1): 17–32. Published online 2017 Nov 3. doi: 10.1016/j.ydbio.2017.10.021

PMCID:: PMC5722660

Abstract Article PDF–2.5M

Select item 553345720.

An ancient neurotrophin receptor code; a single Runx/Cbfβ complex determines somatosensory neuron fate specification in zebrafish

Philia Gau, Andrew Curtright, Logan Condon, David W. Raible, Ajay Dhaka

PLoS Genet. 2017 Jul; 13(7): e1006884. Published online 2017 Jul 14. doi: 10.1371/journal.pgen.1006884

PMCID:: PMC5533457

Abstract Article PDF–58M

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