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Select item 33236961.

Disrupted GABA_AR Trafficking and Synaptic Inhibition in a Mouse Model of Huntington’s Disease

Eunice Y. Yuen, Jing Wei, Ping Zhong, Zhen Yan

Neurobiol Dis. Author manuscript; available in PMC 2013 May 1.

Published in final edited form as: Neurobiol Dis. 2012 May; 46(2): 497–502. Published online 2012 Feb 28. doi: 10.1016/j.nbd.2012.02.015

PMCID:: PMC3323696

Abstract Article PDF–1.6M

Select item 28254912.

Selective Expression of Huntingtin-associated Protein 1 in β-Cells of the Rat Pancreatic Islets

Min Liao, Xingxing Chen, Jinhong Han, Shiming Yang, Ting Peng, He Li

J Histochem Cytochem. 2010 Mar; 58(3): 255–263. doi: 10.1369/jhc.2009.954479

PMCID:: PMC2825491

Abstract Article PDF–1.6M

Select item 5151223.

Huntingtin-associated protein 1 regulates inhibitory synaptic transmission by modulating γ-aminobutyric acid type A receptor membrane trafficking

Josef T. Kittler, Philip Thomas, Verena Tretter, Yuri D. Bogdanov, Volker Haucke, Trevor G. Smart, Stephen J. Moss

Proc Natl Acad Sci U S A. 2004 Aug 24; 101(34): 12736–12741. Published online 2004 Aug 13. doi: 10.1073/pnas.0401860101

PMCID:: PMC515122

Abstract Article PDF–454K

Select item 67930254.

The Cellular and Subcellular Localization of Huntingtin-Associated Protein 1 (HAP1): Comparison with Huntingtin in Rat and Human

Claire-Anne Gutekunst, Shi-Hua Li, Hong Yi, Robert J. Ferrante, Xiao-Jiang Li, Steven M. Hersch

J Neurosci. 1998 Oct 1; 18(19): 7674–7686. doi: 10.1523/JNEUROSCI.18-19-07674.1998

PMCID:: PMC6793025

Abstract Article PDF–1.4M

Select item 66752095.

Regulation of Intracellular Trafficking of Huntingtin-Associated Protein-1 Is Critical for TrkA Protein Levels and Neurite Outgrowth

Juan Rong, John R. McGuire, Zhi-Hui Fang, Guoqing Sheng, Ji-Yeon Shin, Shi-Hua Li, Xiao-Jiang Li

J Neurosci. 2006 May 31; 26(22): 6019–6030. doi: 10.1523/JNEUROSCI.1251-06.2006

PMCID:: PMC6675209

Abstract Article PDF–568K

Select item 39796086.

Huntingtin-associated protein 1 regulates exocytosis, vesicle docking, readily releasable pool size and fusion pore stability in mouse chromaffin cells

Kimberly D Mackenzie, Michael D Duffield, Heshan Peiris, Lucy Phillips, Mark P Zanin, Ee Hiok Teo, Xin-Fu Zhou, Damien J Keating

J Physiol. 2014 Apr 1; 592(Pt 7): 1505–1518. Published online 2014 Feb 17. doi: 10.1113/jphysiol.2013.268342

PMCID:: PMC3979608

Abstract Article PDF–985K

Select item 38389627.

Expression of genes encoding the calcium signalosome in cellular and transgenic models of Huntington's disease

Magdalena Czeredys, Joanna Gruszczynska-Biegala, Teresa Schacht, Axel Methner, Jacek Kuznicki

Front Mol Neurosci. 2013; 6: 42. Published online 2013 Nov 25. doi: 10.3389/fnmol.2013.00042

PMCID:: PMC3838962

Abstract Article PDF–1.0M

Select item 67407318.

Lack of Huntingtin-Associated Protein-1 Causes Neuronal Death Resembling Hypothalamic Degeneration in Huntington's Disease

Shi-Hua Li, Zhao-Xue Yu, Cui-Lin Li, Huu-Phuc Nguyen, Yong-Xing Zhou, Chuxia Deng, Xiao-Jiang Li

J Neurosci. 2003 Jul 30; 23(17): 6956–6964. doi: 10.1523/JNEUROSCI.23-17-06956.2003

PMCID:: PMC6740731

Abstract Article PDF–739K

Select item 38982899.

The Regulation of Autophagosome Dynamics by Huntingtin and HAP1 Is Disrupted by Expression of Mutant Huntingtin, Leading to Defective Cargo Degradation

Yvette C. Wong, Erika L. F. Holzbaur

J Neurosci. 2014 Jan 22; 34(4): 1293–1305. doi: 10.1523/JNEUROSCI.1870-13.2014

PMCID:: PMC3898289

Abstract Article PDF–4.0M

Select item 246738410.

Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice

Guoqing Sheng, Xingshun Xu, Yung-Feng Lin, Chuan-En Wang, Juan Rong, Dongmei Cheng, Junmin Peng, Xiaoyan Jiang, Shi-Hua Li, Xiao-Jiang Li

J Clin Invest. 2008 Aug 1; 118(8): 2785–2795. Published online 2008 Jul 17. doi: 10.1172/JCI35339

PMCID:: PMC2467384

Abstract Article PDF–1.2M

Select item 679272711.

Interaction of Huntingtin-Associated Protein with Dynactin P150^Glued

Shi-Hua Li, Claire-Anne Gutekunst, Steven M. Hersch, Xiao-Jiang Li

J Neurosci. 1998 Feb 15; 18(4): 1261–1269. doi: 10.1523/JNEUROSCI.18-04-01261.1998

PMCID:: PMC6792727

Abstract Article PDF–357K

Select item 370347212.

Loss of Ahi1 Affects Early Development by Impairing BM88/Cend1-Mediated Neuronal Differentiation

Ling Weng, Yung-Feng Lin, Alina L. Li, Chuan-En Wang, Sen Yan, Miao Sun, Marta A. Gaertig, Naureen Mitha, Jun Kosaka, Taketoshi Wakabayashi, Xingshun Xu, Beisha Tang, Shihua Li, Xiao-Jiang Li

J Neurosci. 2013 May 8; 33(19): 8172–8184. doi: 10.1523/JNEUROSCI.0119-13.2013

PMCID:: PMC3703472

Abstract Article PDF–3.8M

Select item 322062313.

Huntingtin and Huntingtin-Associated Protein 1 Influence Neuronal Calcium Signaling Mediated by Inositol-(1,4,5) Triphosphate Receptor Type 1

Tie-Shan Tang, Huiping Tu, Edmond Y.W. Chan, Anton Maximov, Zhengnan Wang, Cheryl L. Wellington, Michael R. Hayden, Ilya Bezprozvanny

Neuron. Author manuscript; available in PMC 2011 Nov 18.

Published in final edited form as: Neuron. 2003 Jul 17; 39(2): 227–239. doi: 10.1016/s0896-6273(03)00366-0

PMCID:: PMC3220623

Abstract Article PDF–3.3M

Select item 284150614.

Deslivery of GABA_ARs to synapses is mediated by HAP1-KIF5 and disrupted by mutant huntingtin

Alison E. Twelvetrees, Eunice Y. Yuen, I. Lorena Arancibia-Carcamo, Andrew F. MacAskill, Philippe Rostaing, Michael J. Lumb, Sandrine Humbert, Antoine Triller, Frederic Saudou, Zhen Yan, Josef T. Kittler

Neuron. Author manuscript; available in PMC 2011 Jan 14.

Published in final edited form as: Neuron. 2010 Jan 14; 65(1): 53–65. doi: 10.1016/j.neuron.2009.12.007

PMCID:: PMC2841506

Abstract Article PDF–4.9M

Select item 282078815.

Huntingtin-associated Protein-1 Interacts with Pro-brain-derived Neurotrophic Factor and Mediates Its Transport and Release

Linda Lin-yan Wu, Yongjun Fan, Shihua Li, Xiao-Jiang Li, Xin-Fu Zhou

J Biol Chem. 2010 Feb 19; 285(8): 5614–5623. Published online 2009 Dec 7. doi: 10.1074/jbc.M109.073197

PMCID:: PMC2820788

Abstract Article PDF–1.4M

Select item 309123416.

Precursor of Brain-derived Neurotrophic Factor (proBDNF) Forms a Complex with Huntingtin-associated Protein-1 (HAP1) and Sortilin That Modulates proBDNF Trafficking, Degradation, and Processing

Miao Yang, Yoon Lim, Xiaojiang Li, Jin-Hua Zhong, Xin-Fu Zhou

J Biol Chem. 2011 May 6; 286(18): 16272–16284. Published online 2011 Feb 28. doi: 10.1074/jbc.M110.195347

PMCID:: PMC3091234

Abstract Article PDF–2.0M

Select item 251688217.

Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons

Emilie Colin, Diana Zala, Géraldine Liot, Hélène Rangone, Maria Borrell-Pagès, Xiao-Jiang Li, Frédéric Saudou, Sandrine Humbert

EMBO J. 2008 Aug 6; 27(15): 2124–2134. Published online 2008 Jul 10. doi: 10.1038/emboj.2008.133

PMCID:: PMC2516882

Abstract Article PDF–2.0M

Select item 259638018.

Huntingtin Regulates RE1-silencing Transcription Factor/Neuron-restrictive Silencer Factor (REST/NRSF) Nuclear Trafficking Indirectly through a Complex with REST/NRSF-interacting LIM Domain Protein (RILP) and Dynactin p150^Glued

Masahito Shimojo

J Biol Chem. 2008 Dec 12; 283(50): 34880–34886. doi: 10.1074/jbc.M804183200

PMCID:: PMC2596380

Abstract Article PDF–477K

Select item 322386119.

Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease

Guy Keryer, Jose R. Pineda, Géraldine Liot, Jinho Kim, Paula Dietrich, Caroline Benstaali, Karen Smith, Fabrice P. Cordelières, Nathalie Spassky, Robert J. Ferrante, Ioannis Dragatsis, Frédéric Saudou

J Clin Invest. 2011 Nov 1; 121(11): 4372–4382. Published online 2011 Oct 10. doi: 10.1172/JCI57552