PMC Links for Gene (Select 29417) - PMC

Griselda Vallejo, Darío Maschi, Ana Cecilia Mestre Citrinovitz, Kazuhiro Aiba, Ricardo Maronna, Victor Yohai, Minoru S. H. Ko, Miguel Beato, Patricia Saragüeta

J Cell Physiol. Author manuscript; available in PMC 2011 Jan 1.

Published in final edited form as: J Cell Physiol. 2010 Jan; 222(1): 127–137. doi: 10.1002/jcp.21929

PMCID:: PMC2840620

Abstract Article PDF–998K

Select item 19421695.

Allelic deletion of the MEN1 gene in duodenal gastrin and somatostatin cell neoplasms and their precursor lesions

M Anlauf, A Perren, T Henopp, T Rudolph, N Garbrecht, A Schmitt, A Raffel, O Gimm, E Weihe, W T Knoefel, H Dralle, Ph U Heitz, P Komminoth, G Klöppel

Gut. 2007 May; 56(5): 637–644. Published online 2007 Jan 27. doi: 10.1136/gut.2006.108910

PMCID:: PMC1942169

Abstract Article PDF–2.6M

Select item 44397406.

Multiple endocrine neoplasia type 1 knockout mice develop parathyroid, pancreatic, pituitary and adrenal tumours with hypercalcaemia, hypophosphataemia and hypercorticosteronaemia

Brian Harding, Manuel C Lemos, Anita A C Reed, Gerard V Walls, Jeshmi Jeyabalan, Michael R Bowl, Hilda Tateossian, Nicky Sullivan, Tertius Hough, William D Fraser, Olaf Ansorge, Michael T Cheeseman, Rajesh V Thakker

Endocr Relat Cancer. 2009 Dec; 16(4): 1313–1327. doi: 10.1677/ERC-09-0082

PMCID:: PMC4439740

Abstract Article PDF–771K

Select item 28399337.

Mutation of Tumor Suppressor Gene Men1 Acutely Enhances Proliferation of Pancreatic Islet Cells

Robert W. Schnepp, Ya-Xiong Chen, Haoren Wang, Tim Cash, Albert Silva, J. Alan Diehl, Eric Brown, Xianxin Hua

Cancer Res. Author manuscript; available in PMC 2010 Mar 16.

Published in final edited form as: Cancer Res. 2006 Jun 1; 66(11): 5707–5715. doi: 10.1158/0008-5472.CAN-05-4518

PMCID:: PMC2839933

Abstract Article PDF–2.5M

Select item 3816828.

Conditional Inactivation of the Men1 Gene Leads to Pancreatic and Pituitary Tumorigenesis but Does Not Affect Normal Development of These Tissues

Christine A. Biondi, Michael G. Gartside, Paul Waring, Kelly A. Loffler, Mitchell S. Stark, Mark A. Magnuson, Graham F. Kay, Nicholas K. Hayward

Mol Cell Biol. 2004 Apr; 24(8): 3125–3131. doi: 10.1128/MCB.24.8.3125-3131.2004

PMCID:: PMC381682

Abstract Article PDF–511K

Select item 191259.

Menin, the product of the MEN1 gene, is a nuclear protein

Siradanahalli C. Guru, Paul K. Goldsmith, A. Lee Burns, Stephen J. Marx, Allen M. Spiegel, Francis S. Collins, Settara C. Chandrasekharappa

Proc Natl Acad Sci U S A. 1998 Feb 17; 95(4): 1630–1634. doi: 10.1073/pnas.95.4.1630

PMCID:: PMC19125

Abstract Article PDF–352K

Select item 1471810.

A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors

Judy S. Crabtree, Peter C. Scacheri, Jerrold M. Ward, Lisa Garrett-Beal, Michael R. Emmert-Buck, Keith A. Edgemon, Dominique Lorang, Steven K. Libutti, Settara C. Chandrasekharappa, Stephen J. Marx, Allen M. Spiegel, Francis S. Collins

Proc Natl Acad Sci U S A. 2001 Jan 30; 98(3): 1118–1123. doi: 10.1073/pnas.98.3.1118

PMCID:: PMC14718

Abstract Article PDF–1.1M

Select item 285858611.

Direct Binding of DNA by Tumor Suppressor Menin

Ping La, Albert C. Silva, Zhaoyuan Hou, Haoren Wang, Robert W. Schnepp, Nieng Yan, Yigong Shi, Xianxin Hua

J Biol Chem. Author manuscript; available in PMC 2010 Apr 22.

Published in final edited form as: J Biol Chem. 2004 Nov 19; 279(47): 49045–49054. Published online 2004 Aug 24. doi: 10.1074/jbc.M409358200

PMCID:: PMC2858586

Abstract Article PDF–1.9M

Select item 285856512.

Tumor Suppressor Menin Regulates Expression of Insulin-Like Growth Factor Binding Protein 2 (IGFBP-2)

PING LA, ROBERT W. SCHNEPP, CLARK D. PETERSEN, ALBERT C. SILVA, XIANXIN HUA

Endocrinology. Author manuscript; available in PMC 2010 Apr 22.

Published in final edited form as: Endocrinology. 2004 Jul; 145(7): 3443–3450. Published online 2004 Mar 24. doi: 10.1210/en.2004-0124

PMCID:: PMC2858565

Abstract Article PDF–1.4M

Select item 285856013.

Menin Induces Apoptosis in Murine Embryonic Fibroblasts

Robert W. Schnepp, Hua Mao, Stephen M. Sykes, Wei-Xing Zong, Albert Silva, Ping La, Xianxin Hua

J Biol Chem. Author manuscript; available in PMC 2010 Apr 22.

Published in final edited form as: J Biol Chem. 2004 Mar 12; 279(11): 10685–10691. Published online 2003 Dec 18. doi: 10.1074/jbc.M308073200

PMCID:: PMC2858560

Abstract Article PDF–1.5M

Select item 18091014.

Of Mice and MEN1: Insulinomas in a Conditional Mouse Knockout

Judy S. Crabtree, Peter C. Scacheri, Jerrold M. Ward, Sara R. McNally, Gary P. Swain, Cristina Montagna, Jeffrey H. Hager, Douglas Hanahan, Helena Edlund, Mark A. Magnuson, Lisa Garrett-Beal, A. Lee Burns, Thomas Ried, Settara C. Chandrasekharappa, Stephen J. Marx, Allen M. Spiegel, Francis S. Collins

Mol Cell Biol. 2003 Sep; 23(17): 6075–6085. doi: 10.1128/MCB.23.17.6075-6085.2003

PMCID:: PMC180910

Abstract Article PDF–1.1M

Select item 3113915.

Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type β signaling

Hiroshi Kaji, Lucie Canaff, Jean-Jacques Lebrun, David Goltzman, Geoffrey N. Hendy

Proc Natl Acad Sci U S A. 2001 Mar 27; 98(7): 3837–3842. Published online 2001 Mar 13. doi: 10.1073/pnas.061358098

PMCID:: PMC31139

Abstract Article PDF–370K

Select item 640057316.

GLP-1 signaling suppresses menin’s transcriptional block by phosphorylation in β cells

Bowen Xing, Jian Ma, Zongzhe Jiang, Zijie Feng, Sunbin Ling, Katy Szigety, Wen Su, Longmei Zhang, Ruirui Jia, Yanmei Sun, Lin Zhang, Xiangchen Kong, Xiaosong Ma, Xianxin Hua

J Cell Biol. 2019 Mar 4; 218(3): 855–870. doi: 10.1083/jcb.201805049

PMCID:: PMC6400573

Abstract Article PDF–3.0M

Select item 384106317.

Altered MENIN expression disrupts the MAFA differentiation pathway in insulinoma

Z Hamze, C Vercherat, A Bernigaud-Lacheretz, Wissam Bazzi, R Bonnavion, J Lu, A Calender, C Pouponnot, P Bertolino, C Roche, R Stein, JY Scoazec, C X Zhang, M Cordier-Bussat

Endocr Relat Cancer. Author manuscript; available in PMC 2014 Dec 1.

Published in final edited form as: Endocr Relat Cancer. 2013 Dec; 20(6): 833–848. Published online 2013 Oct 24. doi: 10.1530/ERC-13-0164

PMCID:: PMC3841063

Abstract Article PDF–1.5M

Select item 125354918.

Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27^Kip1 and p18^INK4c

Satyajit K. Karnik, Christina M. Hughes, Xueying Gu, Orit Rozenblatt-Rosen, Graeme W. McLean, Yue Xiong, Matthew Meyerson, Seung K. Kim

Proc Natl Acad Sci U S A. 2005 Oct 11; 102(41): 14659–14664. Published online 2005 Sep 29. doi: 10.1073/pnas.0503484102

PMCID:: PMC1253549

Abstract Article PDF–682K

Select item 387968619.

Recapitulation of Pancreatic Neuroendocrine Tumors in Human Multiple Endocrine Neoplasia Type I (MEN1) Syndrome via Pdx1-directed Inactivation of Men1

H.-C. Jennifer Shen, Mei He, Anathea Powell, Asha Adem, Dominique Lorang, Charles Heller, Amelia C. Grover, Kris Ylaya, Stephen M. Hewitt, Stephen J. Marx, Allen M. Spiegel, Steven K. Libutti

Cancer Res. Author manuscript; available in PMC 2014 Jan 3.

Published in final edited form as: Cancer Res. 2009 Mar 1; 69(5): 10.1158/0008-5472.CAN-08-3662. Published online 2009 Feb 10. doi: 10.1158/0008-5472.CAN-08-3662

PMCID:: PMC3879686

Abstract Article PDF–6.7M

Select item 132648920.

The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression

Ya-Xiong Chen, Jizhou Yan, Karen Keeshan, Anthony T. Tubbs, Haoren Wang, Albert Silva, Eric J. Brown, Jay L. Hess, Warren S. Pear, Xianxin Hua

Proc Natl Acad Sci U S A. 2006 Jan 24; 103(4): 1018–1023. Published online 2006 Jan 13. doi: 10.1073/pnas.0510347103

PMCID:: PMC1326489

Abstract Article PDF–393K

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