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Select item 72173731.

Downregulation of lncRNA BACE1-AS improves dopamine-dependent oxidative stress in rats with Parkinson’s disease by upregulating microRNA-34b-5p and downregulating BACE1

Yanhong Li, Jian Fang, Zhanye Zhou, Qiyu Zhou, Shibin Sun, Zhikai Jin, Ziming Xi, Jianshe Wei

Cell Cycle. 2020; 19(10): 1158–1171. Published online 2020 Apr 19. doi: 10.1080/15384101.2020.1749447

Expression of Concern in:: Cell Cycle. 2022; 21(24): 2675.

PMCID:: PMC7217373

Abstract Article PDF–5.1M

Select item 56117362.

BACE1 inhibition by microdose lithium formulation NP03 rescues memory loss and early stage amyloid neuropathology

E N Wilson, S Do Carmo, M F Iulita, H Hall, A Ducatenzeiler, A R Marks, S Allard, D T Jia, J Windheim, A C Cuello

Transl Psychiatry. 2017 Aug; 7(8): e1190. Published online 2017 Aug 1. doi: 10.1038/tp.2017.169

PMCID:: PMC5611736

Abstract Article PDF–783K

Select item 3656993.

Differential utilization of upstream AUGs in the β-secretase mRNA suggests that a shunting mechanism regulates translation

George W. Rogers, Jr., Gerald M. Edelman, Vincent P. Mauro

Proc Natl Acad Sci U S A. 2004 Mar 2; 101(9): 2794–2799. Published online 2004 Feb 23. doi: 10.1073/pnas.0308576101

PMCID:: PMC365699

Abstract Article PDF–422K

Select item 108052624.

miR-29c-3p Attenuates β-Amyloid-Induced Neurotoxicity in Alzheimer’s Disease Through Regulating β-Site Amyloid Precursor Protein-Cleaving Enzyme 1

Xiaoping WANG, Min LI, Yinbao HU

Physiol Res. 2023 Dec; 72(6): 833–841. Published online 2023 Dec 31. doi: 10.33549/physiolres.935084

PMCID:: PMC10805262

Abstract Article PDF–993K

Select item 67057175.

BACE1 Cleavage Site Selection Critical for Amyloidogenesis and Alzheimer's Pathogenesis

Shuting Zhang, Zhe Wang, Fang Cai, Mingming Zhang, Yili Wu, Jing Zhang, Weihong Song

J Neurosci. 2017 Jul 19; 37(29): 6915–6925. doi: 10.1523/JNEUROSCI.0340-17.2017

PMCID:: PMC6705717

Abstract Article PDF–2.5M

Select item 57611176.

Plasma long non-coding RNA BACE1 as a novel biomarker for diagnosis of Alzheimer disease

Liang Feng, Yu-Ting Liao, Jin-Cai He, Cheng-Long Xie, Si-Yan Chen, Hui-Hui Fan, Zhi-Peng Su, Zhen Wang

BMC Neurol. 2018; 18: 4. Published online 2018 Jan 9. doi: 10.1186/s12883-017-1008-x

PMCID:: PMC5761117

Abstract Article PDF–1.3M

Select item 53450477.

BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and rats

Martin Weber, Tiffany Wu, William J. Meilandt, Sara L. Dominguez, Hilda O. Solanoy, Janice A. Maloney, Hai Ngu, Miriam Baca, Chung Kung, Lisa Lima, Timothy K. Earr, Daniel Fleck, Shannon D. Shields, William F. Forrest, Oded Foreman, Søren Warming, Ryan J. Watts, Kimberly Scearce-Levie

Sci Rep. 2017; 7: 44249. Published online 2017 Mar 10. doi: 10.1038/srep44249

PMCID:: PMC5345047

Abstract Article PDF–1.1M

Select item 53010448.

miR‐15b mediates oxaliplatin‐induced chronic neuropathic pain through BACE1 down‐regulation

Naomi Ito, Atsushi Sakai, Noriko Miyake, Motoyo Maruyama, Hirotoshi Iwasaki, Koichi Miyake, Takashi Okada, Atsuhiro Sakamoto, Hidenori Suzuki

Br J Pharmacol. 2017 Mar; 174(5): 386–395. Published online 2017 Jan 23. doi: 10.1111/bph.13698

PMCID:: PMC5301044

Abstract Article PDF–522K

Select item 46381029.

Amyloid β-protein oligomers upregulate the β-secretase, BACE1, through a post-translational mechanism involving its altered subcellular distribution in neurons

Naomi Mamada, Daisuke Tanokashira, Ai Hosaka, Fuyuki Kametani, Akira Tamaoka, Wataru Araki

Mol Brain. 2015; 8: 73. Published online 2015 Nov 9. doi: 10.1186/s13041-015-0163-5

PMCID:: PMC4638102

Abstract Article PDF–1.9M

Select item 352228310.

BACE1 Protein Endocytosis and Trafficking Are Differentially Regulated by Ubiquitination at Lysine 501 and the Di-leucine Motif in the Carboxyl Terminus

Eugene L. Kang, Barbara Biscaro, Fabrizio Piazza, Giuseppina Tesco

J Biol Chem. 2012 Dec 14; 287(51): 42867–42880. Published online 2012 Oct 29. doi: 10.1074/jbc.M112.407072

PMCID:: PMC3522283

Abstract Article PDF–2.9M

Select item 272862611.

BACE1 Knock-Outs Display Deficits in Activity-Dependent Potentiation of Synaptic Transmission at Mossy Fiber to CA3 Synapses in the Hippocampus

Hui Wang, Lihua Song, Fiona Laird, Philip C. Wong, Hey-Kyoung Lee

J Neurosci. 2008 Aug 27; 28(35): 8677–8681. doi: 10.1523/JNEUROSCI.2440-08.2008

PMCID:: PMC2728626

Abstract Article PDF–256K

Select item 879452112.

MicroRNA-132-3p alleviates neuron apoptosis and impairments of learning and memory abilities in Alzheimer’s disease by downregulation of HNRNPU stabilized BACE1

Jie Qu, Xiaowei Xiong, Gulibaha Hujie, Jun Ren, Lihui Yan, Liqun Ma

Cell Cycle. 2021; 20(21): 2309–2320. Published online 2021 Sep 29. doi: 10.1080/15384101.2021.1982507

PMCID:: PMC8794521

Abstract Article PDF–2.9M

Select item 780990013.

Nogo-66 promotes β-amyloid protein secretion via NgR/ROCK-dependent BACE1 activation

Qing-Qing Xie, Xiao Feng, Yi-Yun Huang, Nian Fang, Hua Yi, Zi-Jian Wang, Qiao-Yu Cao, Guo-Feng Lou, Jun-Ping Pan, Yang Hu, Fang-Cheng Li, Qing Zheng, Fei Xiao

Mol Med Rep. 2021 Mar; 23(3): 188. Published online 2021 Jan 5. doi: 10.3892/mmr.2021.11827

PMCID:: PMC7809900

Abstract Article PDF–5.8M

Select item 492372714.

Dysregulation of Amyloid-β Protein Precursor, β-Secretase, Presenilin 1 and 2 Genes in the Rat Selectively Vulnerable CA1 Subfield of Hippocampus Following Transient Global Brain Ischemia

Janusz Kocki, Marzena Ułamek-Kozioł, Anna Bogucka-Kocka, Sławomir Januszewski, Mirosław Jabłoński, Paulina Gil-Kulik, Judyta Brzozowska, Alicja Petniak, Wanda Furmaga-Jabłońska, Jacek Bogucki, Stanisław J. Czuczwar, Ryszard Pluta

J Alzheimers Dis. 2015; 47(4): 1047–1056. Published online 2015 Aug 11. doi: 10.3233/JAD-150299

PMCID:: PMC4923727

Abstract Article PDF–423K

Select item 375346915.

The Alzheimer’s β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques

Patty C. Kandalepas, Katherine R. Sadleir, William A. Eimer, Jie Zhao, Daniel A. Nicholson, Robert Vassar

Acta Neuropathol. 2013; 126(3): 329–352. Published online 2013 Jul 3. doi: 10.1007/s00401-013-1152-3

Correction in:: Acta Neuropathol. 2013; 126(4): 623.

PMCID:: PMC3753469

Abstract Article PDF–2.7M

Select item 294914716.

Mutant ubiquitin-mediated β-secretase stability via activation of caspase-3 is related to β-amyloid accumulation in ischemic striatum in rats

Yong Zhang, Man Xiong, Ri-Qiang Yan, Feng-Yan Sun

J Cereb Blood Flow Metab. 2010 Mar; 30(3): 566–575. Published online 2009 Oct 21. doi: 10.1038/jcbfm.2009.228

PMCID:: PMC2949147

Abstract Article PDF–752K

Select item 274778717.

BACE1 regulates voltage-gated sodium channels and neuronal activity

Doo Yeon Kim, Bryce W. Carey, Haibin Wang, Laura A. M. Ingano, Alexander M. Binshtok, Mary H. Wertz, Warren H. Pettingell, Ping He, Virginia M.-Y. Lee, Clifford J. Woolf, Dora M. Kovacs

Nat Cell Biol. Author manuscript; available in PMC 2009 Sep 21.

Published in final edited form as: Nat Cell Biol. 2007 Jul; 9(7): 755–764. Published online 2007 Jun 18. doi: 10.1038/ncb1602