PMC Links for Gene (Select 27343) - PMC

Result Filters

Links from Gene

Items: 1 to 20 of 54

<< First< Prev

Page of 3

Select item 106029141.

Sustained pigmentation causes DNA damage and invokes translesion polymerase Polκ for repair in melanocytes

Madeeha Ghazi, Shivangi Khanna, Yogaspoorthi Subramaniam, Jeyashri Rengaraju, Farina Sultan, Iti Gupta, Kanupriya Sharma, Sudhir Chandna, Rajesh S Gokhale, Vivek T Natarajan

Nucleic Acids Res. 2023 Oct 27; 51(19): 10451–10466. Published online 2023 Sep 11. doi: 10.1093/nar/gkad704

PMCID:: PMC10602914

Abstract Article PDF–1.3M

Select item 52828372.

A fidelity mechanism in DNA polymerase lambda promotes error‐free bypass of 8‐oxo‐dG

Matthew J Burak, Kip E Guja, Elena Hambardjieva, Burak Derkunt, Miguel Garcia‐Diaz

EMBO J. 2016 Sep 15; 35(18): 2045–2059. Published online 2016 Aug 1. doi: 10.15252/embj.201694332

PMCID:: PMC5282837

Abstract Article PDF–2.5M

Select item 51071233.

Estrogen Drives Cellular Transformation and Mutagenesis in Cells Expressing the Breast Cancer-associated R438W DNA Polymerase Lambda Protein

Antonia A. Nemec, Korie B. Bush, Jamie B. Towle-Weicksel, B. Frazier Taylor, Vincent Schulz, Joanne B. Weidhaas, David P. Tuck, Joann B. Sweasy

Mol Cancer Res. Author manuscript; available in PMC 2017 Nov 1.

Published in final edited form as: Mol Cancer Res. 2016 Nov; 14(11): 1068–1077. Published online 2016 Sep 12. doi: 10.1158/1541-7786.MCR-16-0209

PMCID:: PMC5107123

Abstract Article PDF–1.2M

Select item 46307994.

Unlike Catalyzing Error-Free Bypass of 8-oxodGuo, DNA Polymerase λ Is Responsible for a Significant Part of Fapy•dG-Induced G→T Mutations in Human Cells

Paritosh Pande, Kazuhiro Haraguchi, Yu-Lin Jiang, Marc M. Greenberg, Ashis K. Basu

Biochemistry. Author manuscript; available in PMC 2015 Nov 3.

Published in final edited form as: Biochemistry. 2015 Mar 17; 54(10): 1859–1862. Published online 2015 Mar 6. doi: 10.1021/acs.biochem.5b00119

PMCID:: PMC4630799

Abstract Article PDF–776K

Select item 41217975.

Structural basis for the binding and incorporation of nucleotide analogs with L-stereochemistry by human DNA polymerase λ

Rajan Vyas, Walter J. Zahurancik, Zucai Suo

Proc Natl Acad Sci U S A. 2014 Jul 29; 111(30): E3033–E3042. Published online 2014 Jul 11. doi: 10.1073/pnas.1401286111

PMCID:: PMC4121797

Abstract Article PDF–1.9M

Select item 35924386.

Silencing of human DNA polymerase λ causes replication stress and is synthetically lethal with an impaired S phase checkpoint

Elisa Zucca, Federica Bertoletti, Ursula Wimmer, Elena Ferrari, Giuliano Mazzini, Svetlana Khoronenkova, Nicole Grosse, Barbara van Loon, Grigory Dianov, Ulrich Hübscher, Giovanni Maga

Nucleic Acids Res. 2013 Jan; 41(1): 229–241. Published online 2012 Oct 30. doi: 10.1093/nar/gks1016

PMCID:: PMC3592438

Abstract Article PDF–4.4M

Select item 35666407.

DNA Polymerase λ Inactivation by Oxidized Abasic Sites

Adam J. Stevens, Lirui Guan, Katarzyna Bebenek, Thomas A. Kunkel, Marc M. Greenberg

Biochemistry. Author manuscript; available in PMC 2014 Feb 5.

Published in final edited form as: Biochemistry. 2013 Feb 5; 52(5): 975–983. Published online 2013 Jan 18. doi: 10.1021/bi301592x

PMCID:: PMC3566640

Abstract Article PDF–2.5M

Select item 34245638.

The catalytic cycle for ribonucleotide incorporation by human DNA Pol λ

Rajendrakumar A. Gosavi, Andrea F. Moon, Thomas A. Kunkel, Lars C. Pedersen, Katarzyna Bebenek

Nucleic Acids Res. 2012 Aug; 40(15): 7518–7527. Published online 2012 May 14. doi: 10.1093/nar/gks413

PMCID:: PMC3424563

Abstract Article PDF–6.7M

Select item 29575599.

Identification of Critical Residues for the Tight Binding of Both Correct and Incorrect Nucleotides to Human DNA Polymerase λ

Jessica A. Brown, Lindsey R. Pack, Shanen M. Sherrer, Ajay K. Kshetry, Sean A. Newmister, Jason D. Fowler, John-Stephen Taylor, Zucai Suo

J Mol Biol. Author manuscript; available in PMC 2011 Nov 5.

Published in final edited form as: J Mol Biol. 2010 Nov 5; 403(4): 505–515. Published online 2010 Sep 21. doi: 10.1016/j.jmb.2010.09.014

PMCID:: PMC2957559

Abstract Article PDF–1.3M

Select item 293821010.

Loop 1 modulates the fidelity of DNA polymerase λ

Katarzyna Bebenek, Miguel Garcia-Diaz, Rui-Zhe Zhou, Lawrence F. Povirk, Thomas A. Kunkel

Nucleic Acids Res. 2010 Sep; 38(16): 5419–5431. Published online 2010 Apr 30. doi: 10.1093/nar/gkq261

PMCID:: PMC2938210

Abstract Article PDF–8.1M

Select item 281487611.

A Novel Mechanism of Sugar Selection Utilized by a Human X-family DNA Polymerase

Jessica A. Brown, Kevin A. Fiala, Jason D. Fowler, Shanen M. Sherrer, Sean A. Newmister, Wade W. Dyum, Zucai Suo

J Mol Biol. Author manuscript; available in PMC 2011 Jan 15.

Published in final edited form as: J Mol Biol. 2010 Jan 15; 395(2): 282. Published online 2009 Nov 6. doi: 10.1016/j.jmb.2009.11.003

PMCID:: PMC2814876

Abstract Article PDF–1.8M

Select item 276718712.

Scrunching During DNA Repair Synthesis

Miguel Garcia-Diaz, Katarzyna Bebenek, Andres A. Larrea, Jody M. Havener, Lalith Perera, Joseph M. Krahn, Lars C. Pedersen, Dale A. Ramsden, Thomas A. Kunkel

Nat Struct Mol Biol. Author manuscript; available in PMC 2010 Mar 1.

Published in final edited form as: Nat Struct Mol Biol. 2009 Sep; 16(9): 967–972. Published online 2009 Aug 23. doi: 10.1038/nsmb.1654

PMCID:: PMC2767187

Abstract Article PDF–3.2M

Select item 272418513.

Probing Conformational Changes of Human DNA Polymerase λ Using Mass Spectrometry-Based Protein Footprinting

Jason D. Fowler, Jessica A. Brown, Mamuka Kvaratskhelia, Zucai Suo

J Mol Biol. Author manuscript; available in PMC 2010 Jul 17.

Published in final edited form as: J Mol Biol. 2009 Jul 17; 390(3): 368–379. Published online 2009 May 23. doi: 10.1016/j.jmb.2009.05.037

PMCID:: PMC2724185

Abstract Article PDF–4.8M

Select item 258681914.

Catalytic mechanism of human DNA polymerase λ with Mg²⁺ and Mn²⁺ from ab initio quantum mechanical/molecular mechanical studies

G. Andrés Cisneros, Lalith Perera, Miguel García-Díaz, Katarzyna Bebenek, Thomas A. Kunkel, Lee G. Pedersen

DNA Repair (Amst) Author manuscript; available in PMC 2009 Nov 1.

Published in final edited form as: DNA Repair (Amst). 2008 Nov 1; 7(11): 1824–1834. Published online 2008 Aug 30. doi: 10.1016/j.dnarep.2008.07.007

PMCID:: PMC2586819

Abstract Article PDF–2.1M

Select item 257211815.

Control of DNA polymerase λ stability by phosphorylation and ubiquitination during the cell cycle

Ursula Wimmer, Elena Ferrari, Peter Hunziker, Ulrich Hübscher

EMBO Rep. 2008 Oct; 9(10): 1027–1033. Published online 2008 Aug 8. doi: 10.1038/embor.2008.148

PMCID:: PMC2572118

Abstract Article PDF–592K

Select item 197645316.

Error-free bypass of 2-hydroxyadenine by human DNA polymerase λ with Proliferating Cell Nuclear Antigen and Replication Protein A in different sequence contexts

Emmanuele Crespan, Ulrich Hübscher, Giovanni Maga

Nucleic Acids Res. 2007 Aug; 35(15): 5173–5181. Published online 2007 Jul 30. doi: 10.1093/nar/gkm568

PMCID:: PMC1976453

Abstract Article PDF–2.7M

Select item 190410417.

Promiscuous mismatch extension by human DNA polymerase lambda

Angel J. Picher, Miguel García-Díaz, Katarzyna Bebenek, Lars C. Pedersen, Thomas A. Kunkel, Luis Blanco

Nucleic Acids Res. 2006; 34(11): 3259–3266. Published online 2006 Jun 28. doi: 10.1093/nar/gkl377

PMCID:: PMC1904104

Abstract Article PDF–586K

Select item 29026418.

Mutagenesis of human DNA polymerase λ: essential roles of Tyr505 and Phe506 for both DNA polymerase and terminal transferase activities

Igor Shevelev, Giuseppina Blanca, Giuseppe Villani, Kristijan Ramadan, Silvio Spadari, Ulrich Hübscher, Giovanni Maga

Nucleic Acids Res. 2003 Dec 1; 31(23): 6916–6925. doi: 10.1093/nar/gkg896

PMCID:: PMC290264

Abstract Article PDF–295K

Select item 521771319.

Uniform Free-Energy Profiles of the P–O Bond Formation and Cleavage Reactions Catalyzed by DNA Polymerases β and λ

Martin Klvaňa, Urban Bren, Jan Florián

J Phys Chem B. 2016 Dec 29; 120(51): 13017–13030. Published online 2016 Nov 29. doi: 10.1021/acs.jpcb.6b08581

PMCID:: PMC5217713

Abstract Article PDF–2.4M

Select item 477343620.

Impact of ribonucleotide incorporation by DNA polymerases β and λ on oxidative base excision repair

Emmanuele Crespan, Antonia Furrer, Marcel Rösinger, Federica Bertoletti, Elisa Mentegari, Giulia Chiapparini, Ralph Imhof, Nathalie Ziegler, Shana J. Sturla, Ulrich Hübscher, Barbara van Loon, Giovanni Maga

Nat Commun. 2016; 7: 10805. Published online 2016 Feb 26. doi: 10.1038/ncomms10805