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Select item 78946601.

Biallelic Pathogenic GFRA1 Variants Cause Autosomal Recessive Bilateral Renal Agenesis

Veronica Arora, Suliman Khan, Ayman W. El-Hattab, Ratna Dua Puri, Maria Eugenia Rocha, Rijad Merdzanic, Omid Paknia, Christian Beetz, Arndt Rolfs, Aida M. Bertoli-Avella, Peter Bauer, Ishwar C. Verma

J Am Soc Nephrol. 2021 Jan; 32(1): 223–228. Published online 2020 Oct 5. doi: 10.1681/ASN.2020040478

PMCID:: PMC7894660

Abstract Article

Select item 76828962.

Hypomethylation of GDNF family receptor alpha 1 promotes epithelial-mesenchymal transition and predicts metastasis of colorectal cancer

Zhexu Dong, Lei Dai, Yong Zhang, Chao Fang, Gang Shi, Ye Chen, Junshu Li, Qin Wang, Jiamei Fu, Yan Yu, Wenshuang Wang, Lin Cheng, Yi Liu, Yi Lin, Yuan Wang, Qingnan Wang, Huiling Wang, Hantao Zhang, Yujing Zhang, Xiaolan Su, Shuang Zhang, Feng Wang, Meng Qiu, Zongguang Zhou, Hongxin Deng

PLoS Genet. 2020 Nov; 16(11): e1009159. Published online 2020 Nov 11. doi: 10.1371/journal.pgen.1009159

PMCID:: PMC7682896

Abstract Article PDF–4.5M

Select item 69624343.

Impact of GFRA1 gene reactivation by DNA demethylation on prognosis of patients with metastatic colon cancer

Wan-Ru Ma, Peng Xu, Zhao-Jun Liu, Jing Zhou, Lian-Kun Gu, Jun Zhang, Da-Jun Deng

World J Gastroenterol. 2020 Jan 14; 26(2): 184–198. Published online 2020 Jan 14. doi: 10.3748/wjg.v26.i2.184

PMCID:: PMC6962434

Abstract Article PDF–6.7M

Select item 41728054.

Deficiency of GDNF Receptor GFRα1 in Alzheimer's Neurons Results in Neuronal Death

Yoshihiro Konishi, Li-Bang Yang, Ping He, Kristina Lindholm, Bai Lu, Rena Li, Yong Shen

J Neurosci. 2014 Sep 24; 34(39): 13127–13138. doi: 10.1523/JNEUROSCI.2582-13.2014

PMCID:: PMC4172805

Abstract Article PDF–1.9M

Select item 99159025.

The Role of Promyelocytic Leukemia Zinc Finger (PLZF) and Glial-Derived Neurotrophic Factor Family Receptor Alpha 1 (GFRα1) in the Cryopreservation of Spermatogonia Stem Cells

Asma’ ‘Afifah Shamhari, Nur Erysha Sabrina Jefferi, Zariyantey Abd Hamid, Siti Balkis Budin, Muhd Hanis Md Idris, Izatus Shima Taib

Int J Mol Sci. 2023 Feb; 24(3): 1945. Published online 2023 Jan 18. doi: 10.3390/ijms24031945

PMCID:: PMC9915902

Abstract Article PDF–860K

Select item 92734086.

LMX1B Activated Circular RNA GFRA1 Modulates the Tumorigenic Properties and Immune Escape of Prostate Cancer

Min Meng, Yi-chen Wu

J Immunol Res. 2022; 2022: 7375879. Published online 2022 Jul 4. doi: 10.1155/2022/7375879

PMCID:: PMC9273408

Abstract Article PDF–5.0M

Select item 77002937.

Generation of an Oncolytic Herpes Simplex Viral Vector Completely Retargeted to the GDNF Receptor GFRα1 for Specific Infection of Breast Cancer Cells

Bonnie L. Hall, Daniela Leronni, Yoshitaka Miyagawa, William F. Goins, Joseph C. Glorioso, Justus B. Cohen

Int J Mol Sci. 2020 Nov; 21(22): 8815. Published online 2020 Nov 21. doi: 10.3390/ijms21228815

PMCID:: PMC7700293

Abstract Article PDF–2.6M

Select item 73897258.

EZH2对先天性巨结肠结肠组织中GFRα1表达的影响

赵凡, 周崇高, 许光, 马体栋, 夏仁鹏, 李碧香

Zhongguo Dang Dai Er Ke Za Zhi. 2019 Oct 25; 21(10): 1033–1037. Chinese. doi: 10.7499/j.issn.1008-8830.2019.10.015

PMCID:: PMC7389725

Abstract Article PDF–1.4M

Select item 56441849.

circGFRA1 and GFRA1 act as ceRNAs in triple negative breast cancer by regulating miR-34a

Rongfang He, Peng Liu, Xiaoming Xie, Yujuan Zhou, Qianjin Liao, Wei Xiong, Xiaoling Li, Guiyuan Li, Zhaoyang Zeng, Hailin Tang

J Exp Clin Cancer Res. 2017; 36: 145. Published online 2017 Oct 16. doi: 10.1186/s13046-017-0614-1

PMCID:: PMC5644184

Abstract Article PDF–3.6M

Select item 530874510.

Integrated analysis of genome-wide DNA methylation and gene expression profiles identifies potential novel biomarkers of rectal cancer

Jiufeng Wei, Guodong Li, Jinning Zhang, Yuhui Zhou, Shuwei Dang, Hongsheng Chen, Qiong Wu, Ming Liu

Oncotarget. 2016 Sep 20; 7(38): 62547–62558. Published online 2016 Aug 23. doi: 10.18632/oncotarget.11534

PMCID:: PMC5308745

Abstract Article PDF–2.7M

Select item 524083111.

GFRA1 promotes cisplatin-induced chemoresistance in osteosarcoma by inducing autophagy

Mihwa Kim, Ji-Yeon Jung, Seungho Choi, Hyunseung Lee, Liza D. Morales, Jeong-Tae Koh, Sun Hun Kim, Yoo-Duk Choi, Chan Choi, Thomas J. Slaga, Won Jae Kim, Dae Joon Kim

Autophagy. 2017; 13(1): 149–168. Published online 2016 Oct 18. doi: 10.1080/15548627.2016.1239676

PMCID:: PMC5240831

Abstract Article PDF–2.4M

Select item 496057812.

Age‐associated decrease in GDNF and its cognate receptor GFRα‐1 protein expression in human skin

Mohamed A. Adly, Hanan A. Assaf, Mahmoud Rezk Abdelwahed Hussein

Int J Exp Pathol. 2016 Jun; 97(3): 248–256. Published online 2016 Jun 27. doi: 10.1111/iep.12175

PMCID:: PMC4960578

Abstract Article PDF–1.5M

Select item 355146813.

Traditional and targeted exome sequencing reveals common, rare and novel functional deleterious variants in RET signaling complex in a cohort of living US patients with urinary tract malformations

Rajshekhar Chatterjee, Enrique Ramos, Mary Hoffman, Jessica VanWinkle, Daniel R Martin, Thomas K Davis, Masato Hoshi, Stanley P Hmiel, Anne Beck, Keith Hruska, Doug Coplen, Helen Liapis, Robi Mitra, Todd Druley, Paul Austin, Sanjay Jain

Hum Genet. Author manuscript; available in PMC 2013 Nov 1.

Published in final edited form as: Hum Genet. 2012 Nov; 131(11): 1725–1738. Published online 2012 Jun 23. doi: 10.1007/s00439-012-1181-3

PMCID:: PMC3551468

Abstract Article PDF–2.3M

Select item 309415014.

Glial cell line–derived neurotrophic factor receptor–alpha 1 expressed in striatum in trans regulates development and injury response of dopamine neurons of the substantia nigra

Nikolai Kholodilov, Sang Ryong Kim, Olga Yarygina, Tatyana Kareva, Jin Whan Cho, Amy Baohan, Robert E. Burke

J Neurochem. Author manuscript; available in PMC 2012 Feb 1.

Published in final edited form as: J Neurochem. 2011 Feb; 116(4): 486–498. Published online 2011 Jan 19. doi: 10.1111/j.1471-4159.2010.07128.x

PMCID:: PMC3094150

Abstract Article PDF–2.2M

Select item 857279215.

CircGFRA1 facilitates the malignant progression of HER‐2‐positive breast cancer via acting as a sponge of miR‐1228 and enhancing AIFM2 expression

Meiheban Bazhabayi, Xingsheng Qiu, Xing Li, Anli Yang, Wei Wen, Xiaoli Zhang, Xiangsheng Xiao, Rongfang He, Peng Liu

J Cell Mol Med. 2021 Nov; 25(21): 10248–10256. Published online 2021 Oct 20. doi: 10.1111/jcmm.16963

PMCID:: PMC8572792

Abstract Article PDF–1.1M

Select item 775577216.

LncRNA LINC00210 regulated radiosensitivity of osteosarcoma cells via miR‐342‐3p/GFRA1 axis

Pan He, Yong‐qiang Xu, Zhi‐jun Wang, Bin Sheng

J Clin Lab Anal. 2020 Dec; 34(12): e23540. Published online 2020 Aug 25. doi: 10.1002/jcla.23540

PMCID:: PMC7755772

Abstract Article PDF–1.6M

Select item 266331717.

Ape1/Ref-1 Induces Glial Cell-Derived Neurotropic Factor (GDNF) Responsiveness by Upregulating GDNF Receptor α1 Expression

Mi-Hwa Kim, Hong-Beum Kim, Samudra Acharya, Hong-Moon Sohn, Jae Yeoul Jun, In-Youb Chang, Ho Jin You

Mol Cell Biol. 2009 Apr; 29(8): 2264–2277. Published online 2009 Feb 2. doi: 10.1128/MCB.01484-08

PMCID:: PMC2663317

Abstract Article PDF–1.8M

Select item 457938018.

Lipid Rafts Are Physiologic Membrane Microdomains Necessary for the Morphogenic and Developmental Functions of Glial Cell Line-Derived Neurotrophic Factor In Vivo

Cynthia C. Tsui, Nicole A. Gabreski, Sarah J. Hein, Brian A. Pierchala

J Neurosci. 2015 Sep 23; 35(38): 13233–13243. doi: 10.1523/JNEUROSCI.2935-14.2015

PMCID:: PMC4579380

Abstract Article PDF–2.3M

Select item 402486319.

GFRα1 released by nerves enhances cancer cell perineural invasion through GDNF-RET signaling

Shuangba He, Chun-Hao Chen, Natalya Chernichenko, Shizhi He, Richard L. Bakst, Fernando Barajas, Sylvie Deborde, Peter J. Allen, Efsevia Vakiani, Zhenkun Yu, Richard J. Wong

Proc Natl Acad Sci U S A. 2014 May 13; 111(19): E2008–E2017. Published online 2014 Apr 28. doi: 10.1073/pnas.1402944111

PMCID:: PMC4024863

Abstract Article PDF–1.7M

Select item 356221120.

Prognostic significance of the expression of GFRα1, GFRα3 and Syndecan-3, proteins binding ARTEMIN, in mammary carcinoma

Zheng-Sheng Wu, Vijay Pandey, Wen-Yong Wu, Shan Ye, Tao Zhu, Peter E Lobie

BMC Cancer. 2013; 13: 34. Published online 2013 Jan 26. doi: 10.1186/1471-2407-13-34

PMCID:: PMC3562211

Abstract Article PDF–2.5M

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