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Items: 1 to 20 of 143

1.
BAV-associated Regulatory Regions Reveal GATA4 Regulation and Function during hiPSC-based Endothelial-Mesenchymal Transition
Tingting Huang, Jiaxi Cheng, Hao Feng, Wei Zhou, Ping Qiu, Dong Zhou, Dongshan Yang, Jifeng Zhang, Cristen Willer, Y. Eugene Chen, Dogukan Mizrak, Bo Yang
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2024 Feb 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2023 Feb; 43(2): 312–322. Published online 2022 Dec 15. doi: 10.1161/ATVBAHA.122.318566
PMCID:
PMC10038164
AbstractArticlePDF–1014K
2.
GATA-4 Variants in Two Unrelated Cases with 46, XY Disorder of Sex Development and Review of the Literature
Nurullah Çelik, Hande Küçük Kurtulgan, Fatih Kılıçbay, Gaffari Tunç, Ayça Kömürlüoğlu, Onur Taşçı, Cemile Ece Çağlar Şimşek, Taha Çınar, Yeşim Sıdar Duman
J Clin Res Pediatr Endocrinol. 2022 Dec; 14(4): 469–474. Published online 2022 Dec 1. doi: 10.4274/jcrpe.galenos.2021.2021.0112
PMCID:
PMC9724050
AbstractArticlePDF–807K
3.
The Transcription Factor GATA4 Regulates Cell Type-Specific Splicing through Direct Interaction with RNA in Human iPS-Derived Cardiac Progenitors
Lili Zhu, Krishna Choudhary, Barbara Gonzalez-Teran, Yen-Sin Ang, Reuben Thomas, Nicole R. Stone, Lei Liu, Ping Zhou, Chenchen Zhu, Hongmei Ruan, Yu Huang, Shibo Jin, Angelo Pelonero, Frances Koback, Arun Padmanabhan, Nandhini Sadagopan, Austin Hsu, Mauro W. Costa, Casey A. Gifford, Joke van Bemmel, Ruth Hüttenhain, Vasanth Vedantham, Bruce R. Conklin, Brian L. Black, Benoit G. Bruneau, Lars Steinmetz, Nevan J. Krogan, Katherine S. Pollard, Deepak Srivastava
Circulation. Author manuscript; available in PMC 2023 Sep 6.
Published in final edited form as: Circulation. 2022 Sep 6; 146(10): 770–787. Published online 2022 Aug 8. doi: 10.1161/CIRCULATIONAHA.121.057620
PMCID:
PMC9452483
AbstractArticlePDF–2.3M
4.
Multimerization of the GATA4 transcription factor regulates transcriptional activity and cardiomyocyte hypertrophic response
Satoshi Shimizu, Yoichi Sunagawa, Naruto Hajika, Natsumi Yorimitsu, Yasufumi Katanasaka, Masafumi Funamoto, Yusuke Miyazaki, Nurmila Sari, Kana Shimizu, Koji Hasegawa, Tatsuya Morimoto
Int J Biol Sci. 2022; 18(3): 1079–1095. Published online 2022 Jan 1. doi: 10.7150/ijbs.65664
PMCID:
PMC8771830
AbstractArticlePDF–1.9M
5.
Identification and functional study of GATA4 gene regulatory variants in atrial septal defects
Dongchen Fan, Shuchao Pang, Jing Chen, Jiping Shan, Qianjin Cheng, Bo Yan
BMC Cardiovasc Disord. 2021; 21: 321. Published online 2021 Jun 30. doi: 10.1186/s12872-021-02136-w
PMCID:
PMC8243876
AbstractArticlePDF–1.1M
6.
Identification and functional study of GATA4 gene regulatory variants in type 2 diabetes mellitus
Liangcai Ding, Mengdi Cai, Lu Chen, Han Yan, Shicheng Lu, Shuchao Pang, Bo Yan
BMC Endocr Disord. 2021; 21: 73. Published online 2021 Apr 17. doi: 10.1186/s12902-021-00739-0
PMCID:
PMC8052808
AbstractArticlePDF–1023K
7.
Mutational analysis of the GATA4 gene in Chinese men with nonobstructive azoospermia
Xu Zhang, Tai-Jian Zhang, Wen Liu, Yun-Na Ning, Yue-Hong Bian, Yong-Zhi Cao, Hong-Bin Liu, Jin-Long Ma, Hao-Bo Zhang
Asian J Androl. 2021 Mar-Apr; 23(2): 205–210. Published online 2020 Aug 28. doi: 10.4103/aja.aja_33_20
PMCID:
PMC7991814
AbstractArticlePDF–875K
8.
GATA4 blocks squamous epithelial cell gene expression in human esophageal squamous cells
Roman Stavniichuk, Ann DeLaForest, Cayla A. Thompson, James Miller, Rhonda F. Souza, Michele A. Battle
Sci Rep. 2021; 11: 3206. Published online 2021 Feb 5. doi: 10.1038/s41598-021-82557-x
PMCID:
PMC7864948
AbstractArticlePDF–5.4M
9.
The M310T mutation in the GATA4 gene is a novel pathogenic target of the familial atrial septal defect
Haisong Bu, Guowen Sun, Yun Zhu, Yifeng Yang, Zhiping Tan, Tianli Zhao, Shijun Hu
BMC Cardiovasc Disord. 2021; 21: 12. Published online 2021 Jan 6. doi: 10.1186/s12872-020-01822-5
PMCID:
PMC7788758
AbstractArticlePDF–1.9M
10.
GATA4 mutations are a cause of neonatal and childhood-onset diabetes
Charles Shaw-Smith, Elisa De Franco, Hana Lango Allen, Marta Batlle, Sarah E. Flanagan, Maciej Borowiec, Craig E. Taplin, Janiëlle van Alfen-van der Velden, Jaime Cruz-Rojo, Guiomar Perez de Nanclares, Zosia Miedzybrodzka, Grazyna Deja, Iwona Wlodarska, Wojciech Mlynarski, Jorge Ferrer, Andrew T. Hattersley, Sian Ellard
Diabetes. Author manuscript; available in PMC 2019 Nov 12.
Published in final edited form as: Diabetes. 2014 Aug 1; 63(8): 2888–2894. Published online 2014 Apr 2. doi: 10.2337/db14-0061
PMCID:
PMC6850908
AbstractArticlePDF–629K
11.
GATA4 screening in Iranian patients of various ethnicities affected with congenital heart disease: Co‐occurrence of a novel de novo translocation (5;7) and a likely pathogenic heterozygous GATA4 mutation in a family with autosomal dominant congenital heart disease
Samira Kalayinia, Majid Maleki, Hassan Rokni‐Zadeh, Majid Changi‐Ashtiani, Hassan Ahangar, Alireza Biglari, Tina Shahani, Nejat Mahdieh
J Clin Lab Anal. 2019 Sep; 33(7): e22923. Published online 2019 May 22. doi: 10.1002/jcla.22923
PMCID:
PMC6757118
AbstractArticlePDF–863K
12.
Functional analysis of the congenital heart disease-associated GATA4 H436Y mutation in vitro
Tao Fang, Yanjie Zhu, Anlan Xu, Yanli Zhang, Qingfa Wu, Guoying Huang, Wei Sheng, Mingwu Chen
Mol Med Rep. 2019 Sep; 20(3): 2325–2331. Published online 2019 Jul 9. doi: 10.3892/mmr.2019.10481
PMCID:
PMC6691264
AbstractArticlePDF–565K
13.
GATA4 molecular screening and assessment of environmental risk factors in a Moroccan cohort with tetralogy of Fallot
Ihssane EL Bouchikhi, Khadija Belhassan, Fatima Zohra Moufid, Mohammed Iraqui Houssaini, Laila Bouguenouch, Imane Samri, Mohamed Bouhrim, Karim Ouldim, Samir Atmani
Afr Health Sci. 2018 Dec; 18(4): 922–930. doi: 10.4314/ahs.v18i4.11
PMCID:
PMC6354854
AbstractArticlePDF–371K
14.
GATA4 inhibits cell differentiation and proliferation in pancreatic cancer
Yan Gong, Liang Zhang, Aiqun Zhang, Xin Chen, Peng Gao, Qiang Zeng
PLoS One. 2018; 13(8): e0202449. Published online 2018 Aug 24. doi: 10.1371/journal.pone.0202449
PMCID:
PMC6108473
AbstractArticlePDF–9.3M
15.
Association Analysis Between Genetic Variation in GATA Binding Protein 4 (GATA4) and Alcohol Use Disorder
Kelsey L Mauro, Sarah G Helton, Dan B Rosoff, Audrey Luo, Melanie Schwandt, Jeesun Jung, Jisoo Lee, Christine Muench, Falk W Lohoff
Alcohol Alcohol. 2018 Jul; 53(4): 361–367. Published online 2018 Feb 5. doi: 10.1093/alcalc/agx120
PMCID:
PMC6016699
AbstractArticlePDF–144K
16.
Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve
Bo Yang, Wei Zhou, Jiao Jiao, Jonas B. Nielsen, Michael R. Mathis, Mahyar Heydarpour, Guillaume Lettre, Lasse Folkersen, Siddharth Prakash, Claudia Schurmann, Lars Fritsche, Gregory A. Farnum, Maoxuan Lin, Mohammad Othman, Whitney Hornsby, Anisa Driscoll, Alexandra Levasseur, Marc Thomas, Linda Farhat, Marie-Pierre Dubé, Eric M. Isselbacher, Anders Franco-Cereceda, Dong-chuan Guo, Erwin P. Bottinger, G. Michael Deeb, Anna Booher, Sachin Kheterpal, Y. Eugene Chen, Hyun Min Kang, Jacob Kitzman, Heather J. Cordell, Bernard D. Keavney, Judith A. Goodship, Santhi K. Ganesh, Gonçalo Abecasis, Kim A. Eagle, Alan P. Boyle, Ruth J. F. Loos, Per Eriksson, Jean-Claude Tardif, Chad M. Brummett, Dianna M. Milewicz, Simon C. Body, Cristen J. Willer
Nat Commun. 2017; 8: 15481. Published online 2017 May 25. doi: 10.1038/ncomms15481
PMCID:
PMC5458508
AbstractArticlePDF–980K
17.
Associations of GATA4 genetic mutations with the risk of congenital heart disease: A meta-analysis
Yanwei Zhang, Feng Ai, Jiayong Zheng, Bangtian Peng
Medicine (Baltimore) 2017 May; 96(18): e6857. Published online 2017 May 5. doi: 10.1097/MD.0000000000006857
PMCID:
PMC5419936
AbstractArticlePDF–722K
18.
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis
Yen-Sin Ang, Renee N. Rivas, Alexandre J. S. Ribeiro, Rohith Srivas, Janell Rivera, Nicole R. Stone, Karishma Pratt, Tamer M. A. Mohamed, Ji-Dong Fu, C. Ian Spencer, Nathaniel D. Tippens, Molong Li, Anil Narasimha, Ethan Radzinsky, Anita Moon-Grady, Haiyuan Yu, Beth L. Pruitt, Michael Snyder, Deepak Srivastava
Cell. Author manuscript; available in PMC 2017 Dec 15.
Published in final edited form as: Cell. 2016 Dec 15; 167(7): 1734–1749.e22. doi: 10.1016/j.cell.2016.11.033
PMCID:
PMC5180611
AbstractArticlePDF–3.3M
19.
Analysis of Rare Variants in the Alcohol Dependence Candidate Gene GATA4
Franziska Degenhardt, Laurenz Krämer, Josef Frank, Jens Treutlein, Stefanie Heilmann‐Heimbach, Julian Hecker, Heide Löhlein Fier, Maren Lang, Stephanie H. Witt, Anna C. Koller, Karl Mann, Sabine Hoffmann, Falk Kiefer, Rainer Spanagel, Marcella Rietschel, Markus M. Nöthen
Alcohol Clin Exp Res. 2016 Aug; 40(8): 1627–1632. Published online 2016 Jul 4. doi: 10.1111/acer.13125
PMCID:
PMC5108491
AbstractArticlePDF–123K
20.
The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4
Chanhee Kang, Qikai Xu, Timothy D. Martin, Mamie Z. Li, Marco Demaria, Liviu Aron, Tao Lu, Bruce A. Yankner, Judith Campisi, Stephen J. Elledge
Science. Author manuscript; available in PMC 2016 Jul 12.
Published in final edited form as: Science. 2015 Sep 25; 349(6255): aaa5612. doi: 10.1126/science.aaa5612
PMCID:
PMC4942138
AbstractArticlePDF–2.1M

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