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Items: 1 to 20 of 30

1.
Biallelic variants in FBXL3 cause intellectual disability, delayed motor development and short stature
Muhammad Ansar, Sohail Aziz Paracha, Alessandro Serretti, Muhammad T Sarwar, Jamshed Khan, Emmanuelle Ranza, Emilie Falconnet, Justyna Iwaszkiewicz, Sayyed Fahim Shah, Azhar Ali Qaisar, Federico A Santoni, Vincent Zoete, Andre Megarbane, Jawad Ahmed, Roberto Colombo, Periklis Makrythanasis, Stylianos E Antonarakis
Hum Mol Genet. 2019 Mar 15; 28(6): 972–979. Published online 2018 Nov 26. doi: 10.1093/hmg/ddy406
PMCID:
PMC6400105
AbstractArticlePDF–3.9M
2.
miR-181d and c-myc-mediated inhibition of CRY2 and FBXL3 reprograms metabolism in colorectal cancer
Xiaofeng Guo, Yuekun Zhu, Xinya Hong, Mukun Zhang, Xingfeng Qiu, Zhenfa Wang, Zhongquan Qi, Xuehui Hong
Cell Death Dis. 2017 Jul; 8(7): e2958. Published online 2017 Jul 27. doi: 10.1038/cddis.2017.300
PMCID:
PMC5550850
AbstractArticlePDF–3.9M
3.
A Cryptochrome 2 mutation yields advanced sleep phase in humans
Arisa Hirano, Guangsen Shi, Christopher R Jones, Anna Lipzen, Len A Pennacchio, Ying Xu, William C Hallows, Thomas McMahon, Maya Yamazaki, Louis J Ptáček, Ying-Hui Fu
eLife. 2016; 5: e16695. Published online 2016 Aug 16. doi: 10.7554/eLife.16695
PMCID:
PMC5398888
AbstractArticlePDF–3.5M
4.
CRY2 and FBXL3 cooperatively degrade c-MYC
Anne-Laure Huber, Stephanie J. Papp, Alanna B. Chan, Emma Henriksson, Sabine D. Jordan, Anna Kriebs, Madelena Nguyen, Martina Wallace, Zhizhong Li, Christian M. Metallo, Katja A. Lamia
Mol Cell. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Mol Cell. 2016 Nov 17; 64(4): 774–789. Published online 2016 Nov 10. doi: 10.1016/j.molcel.2016.10.012
PMCID:
PMC5123859
AbstractArticlePDF–2.0M
5.
Distinct and Separable Roles for Endogenous CRY1 and CRY2 within the Circadian Molecular Clockwork of the Suprachiasmatic Nucleus, as Revealed by the Fbxl3Afh Mutation
Sneha N. Anand, Elizabeth S. Maywood, Johanna E. Chesham, Greg Joynson, Gareth T. Banks, Michael H. Hastings, Patrick M. Nolan
J Neurosci. 2013 Apr 24; 33(17): 7145–7153. doi: 10.1523/JNEUROSCI.4950-12.2013
PMCID:
PMC4104284
AbstractArticlePDF–892K
6.
Cand1 Promotes Assembly of New SCF Complexes Through Dynamic Exchange of F-box Proteins
Nathan W. Pierce, J. Eugene Lee, Xing Liu, Michael J. Sweredoski, Robert L. J. Graham, Elizabeth A. Larimore, Michael Rome, Ning Zheng, Bruce E. Clurman, Sonja Hess, Shu-ou Shan, Raymond J. Deshaies
Cell. Author manuscript; available in PMC 2013 Sep 28.
Published in final edited form as: Cell. 2013 Mar 28; 153(1): 206–215. Published online 2013 Feb 28. doi: 10.1016/j.cell.2013.02.024
PMCID:
PMC3656483
AbstractArticlePDF–3.4M
7.
SCFFbxl3 Ubiquitin Ligase Targets Cryptochromes at Their Cofactor Pocket
Weiman Xing, Luca Busino, Thomas R. Hinds, Samuel T. Marionni, Nabiha H. Saifee, Matthew F. Bush, Michele Pagano, Ning Zheng
Nature. Author manuscript; available in PMC 2013 Oct 4.
Published in final edited form as: Nature. 2013 Apr 4; 496(7443): 64–68. Published online 2013 Mar 17. doi: 10.1038/nature11964
PMCID:
PMC3618506
AbstractArticlePDF–1.4M
8.
The GSK-3β-FBXL21 Axis Contributes to Circadian TCAP Degradation and Skeletal Muscle Function
Marvin Wirianto, Jiah Yang, Eunju Kim, Song Gao, Keshav Raj Paudel, Jong Min Choi, Jeehwan Choe, Gabrielle F. Gloston, Precious Ademoji, Randika Parakramaweera, Jianping Jin, Karyn A. Esser, Sung Yun Jung, Yong-Jian Geng, Hyun Kyoung Lee, Zheng Chen, Seung-Hee Yoo
Cell Rep. Author manuscript; available in PMC 2021 Jul 23.
Published in final edited form as: Cell Rep. 2020 Sep 15; 32(11): 108140. doi: 10.1016/j.celrep.2020.108140
PMCID:
PMC8299398
AbstractArticlePDF–2.3M
9.
TAK1 Is a Novel Target in Hepatocellular Carcinoma and Contributes to Sorafenib Resistance
Shunjie Xia, Lin Ji, Liye Tao, Yu Pan, Zhongjie Lin, Zhe Wan, Haoqi Pan, Jie Zhao, Liuxin Cai, Junjie Xu, Xiujun Cai
Cell Mol Gastroenterol Hepatol. 2021; 12(3): 1121–1143. Published online 2021 May 5. doi: 10.1016/j.jcmgh.2021.04.016
PMCID:
PMC8350196
AbstractArticlePDF–9.2M
10.
Substrate Binding Promotes Formation of the Skp1-Cul1-Fbxl3 (SCFFbxl3) Protein Complex
Kanae Yumimoto, Tetsuya Muneoka, Tomohiro Tsuboi, Keiichi I. Nakayama
J Biol Chem. 2013 Nov 8; 288(45): 32766–32776. Published online 2013 Sep 30. doi: 10.1074/jbc.M113.511303
PMCID:
PMC3820910
AbstractArticlePDF–1.3M
11.
PTEN counteracts FBXL2 to promote IP3R3– and Ca2+–mediated apoptosis limiting tumour growth
Shafi Kuchay, Carlotta Giorgi, Daniele Simoneschi, julia Pagan, Sonia Missiroli, Anita Saraf, Laurence Florens, Michael P. Washburn, Ana Collazo-Lorduy, Mireia Castillo-Martin, Carlos Cordon-Cardo, Said M. Sebti, Paolo Pinton, Michele Pagano
Nature. Author manuscript; available in PMC 2017 Oct 4.
Published in final edited form as: Nature. 2017 Jun 22; 546(7659): 554–558. Published online 2017 Jun 14. doi: 10.1038/nature22965
PMCID:
PMC5627969
AbstractArticlePDF–1.3M
12.
FBXW7 triggers degradation of KMT2D to favor growth of diffuse large B-cell lymphoma cells
Rizwan Saffie, Nan Zhou, Delphine Rolland, Özlem Önder, Venkatesha Basrur, Sydney Campbell, Kathryn E. Wellen, Kojo S.J. Elenitoba-Johnson, Brian C. Capell, Luca Busino
Cancer Res. Author manuscript; available in PMC 2021 Jun 15.
Published in final edited form as: Cancer Res. 2020 Jun 15; 80(12): 2498–2511. Published online 2020 Apr 29. doi: 10.1158/0008-5472.CAN-19-2247
PMCID:
PMC7417195
AbstractArticlePDF–2.1M
13.
The ULK1-FBXW5-SEC23B nexus controls autophagy
Yeon-Tae Jeong, Daniele Simoneschi, Sarah Keegan, David Melville, Natalia S Adler, Anita Saraf, Laurence Florens, Michael P Washburn, Claudio N Cavasotto, David Fenyö, Ana Maria Cuervo, Mario Rossi, Michele Pagano
eLife. 2018; 7: e42253. Published online 2018 Dec 31. doi: 10.7554/eLife.42253
PMCID:
PMC6351106
AbstractArticlePDF–4.4M
14.
Cryptochromes-mediated Inhibition of the CRL4Cop1-Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism
Luca Rizzini, Daniel C. Levine, Mark Perelis, Joseph Bass, Clara B. Peek, Michele Pagano
Curr Biol. Author manuscript; available in PMC 2020 Jun 17.
Published in final edited form as: Curr Biol. 2019 Jun 17; 29(12): 1954–1962.e4. Published online 2019 May 30. doi: 10.1016/j.cub.2019.04.073
PMCID:
PMC6581574
AbstractArticlePDF–1.1M
15.
Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette Syndrome and Obsessive-Compulsive Disorder
Dongmei Yu, Carol A. Mathews, Jeremiah M. Scharf, Benjamin M. Neale, Lea K. Davis, Eric R. Gamazon, Eske M. Derks, Patrick Evans, Christopher K. Edlund, Jacquelyn Crane, Jesen A. Fagerness, Lisa Osiecki, Patience Gallagher, Gloria Gerber, Stephen Haddad, Cornelia Illmann, Lauren M. McGrath, Catherine Mayerfeld, Sampath Arepalli, Cristina Barlassina, Cathy L. Barr, Laura Bellodi, Fortu Benarroch, Gabriel Bedoya Berrió, O. Joseph Bienvenu, Donald Black, Michael H. Bloch, Helena Brentani, Ruth D. Bruun, Cathy L. Budman, Beatriz Camarena, Desmond D. Campbell, Carolina Cappi, Julio C. Cardona Silgado, Maria C. Cavallini, Denise A. Chavira, Sylvain Chouinard, Edwin H. Cook, M. R. Cookson, Vladimir Coric, Bernadette Cullen, Daniele Cusi, Richard Delorme, Damiaan Denys, Yves Dion, Valsama Eapen, Karin Egberts, Peter Falkai, Thomas Fernandez, Eduardo Fournier, Helena Garrido, Daniel Geller, Donald Gilbert, Simon L. Girard, Hans J. Grabe, Marco A. Grados, Benjamin D. Greenberg, Varda Gross-Tsur, Edna Grünblatt, John Hardy, Gary A. Heiman, Sian M.J. Hemmings, Luis D. Herrera, Dianne M. Hezel, Pieter J. Hoekstra, Joseph Jankovic, James L. Kennedy, Robert A. King, Anuar I. Konkashbaev, Barbara Kremeyer, Roger Kurlan, Nuria Lanzagorta, Marion Leboyer, James F. Leckman, Leonhard Lennertz, Chunyu Liu, Christine Lochner, Thomas L. Lowe, Sara Lupoli, Fabio Macciardi, Wolfgang Maier, Paolo Manunta, Maurizio Marconi, James T. McCracken, Sandra C. Mesa Restrepo, Rainald Moessner, Priya Moorjani, Jubel Morgan, Heike Muller, Dennis L. Murphy, Allan L. Naarden, William Cornejo Ochoa, Roel A. Ophoff, Andrew J. Pakstis, Michele T. Pato, Carlos N. Pato, John Piacentini, Christopher Pittenger, Yehuda Pollak, Scott L. Rauch, Tobias Renner, Victor I. Reus, Margaret A. Richter, Mark A. Riddle, Mary M. Robertson, Roxana Romero, Maria C. Rosário, David Rosenberg, Stephan Ruhrmann, Chiara Sabatti, Erika Salvi, Aline S. Sampaio, Jack Samuels, Paul Sandor, Susan K. Service, Brooke Sheppard, Harvey S. Singer, Jan H. Smit, Dan J. Stein, Eric Strengman, Jay A. Tischfield, Maurizio Turiel, Ana V. Valencia Duarte, Homero Vallada, Jeremy Veenstra-VanderWeele, Prof. Susanne Walitza, John Walkup, Ying Wang, Mike Weale, Robert Weiss, Jens R. Wendland, Herman G.M. Westenberg, Yin Yao, Ana G. Hounie, Euripedes C. Miguel, Humberto Nicolini, Michael Wagner, Andres Ruiz-Linares, Danielle C. Cath, William McMahon, Danielle Posthuma, Ben A. Oostra, Gerald Nestadt, Guy A. Rouleau, Shaun Purcell, Michael A. Jenike, Peter Heutink, Gregory L. Hanna, David V. Conti, Paul D. Arnold, Nelson Freimer, S. Evelyn Stewart, James A. Knowles, Nancy J. Cox, David L. Pauls
Am J Psychiatry. Author manuscript; available in PMC 2016 Jan 1.
Published in final edited form as: Am J Psychiatry. 2015 Jan 1; 172(1): 82–93. Published online 2014 Oct 31. doi: 10.1176/appi.ajp.2014.13101306
PMCID:
PMC4282594
AbstractArticlePDF–1005K
16.
Systemwide disassembly and assembly of SCF ubiquitin ligase complexes
Kheewoong Baek, Daniel C. Scott, Lukas T. Henneberg, Moeko T. King, Matthias Mann, Brenda A. Schulman
Cell. 2023 Apr 27; 186(9): 1895–1911.e21. doi: 10.1016/j.cell.2023.02.035
Correction in:
Cell. 2023 May 25; 186(11): 2492.
PMCID:
PMC10156175
AbstractArticle
17.
Composition and regulation of the cellular repertoire of SCF ubiquitin ligases
Justin M. Reitsma, Xing Liu, Kurt M. Reichermeier, Annie Moradian, Michael J. Sweredoski, Sonja Hess, Raymond J. Deshaies
Cell. Author manuscript; available in PMC 2018 Nov 30.
Published in final edited form as: Cell. 2017 Nov 30; 171(6): 1326–1339.e14. Published online 2017 Nov 2. doi: 10.1016/j.cell.2017.10.016
PMCID:
PMC5711595
AbstractArticlePDF–2.4M
18.
Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation
Daniel C. Scott, David Y. Rhee, David M. Duda, Ian R. Kelsall, Jennifer L. Olszewski, Joao A. Paulo, Annemieke de Jong, Huib Ovaa, Arno F. Alpi, J. Wade Harper, Brenda A. Schulman
Cell. Author manuscript; available in PMC 2017 Aug 25.
Published in final edited form as: Cell. 2016 Aug 25; 166(5): 1198–1214.e24. doi: 10.1016/j.cell.2016.07.027
PMCID:
PMC5091668
AbstractArticlePDF–4.2M
19.
DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization
Stephanie J Papp, Anne-Laure Huber, Sabine D Jordan, Anna Kriebs, Madelena Nguyen, James J Moresco, John R Yates, III, Katja A Lamia
eLife. 2015; 4: e04883. Published online 2015 Mar 10. doi: 10.7554/eLife.04883
PMCID:
PMC4352707
AbstractArticlePDF–3.4M
20.
Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition
Mikko Taipale, Irina Krykbaeva, Martina Koeva, Can Kayatekin, Kenneth D. Westover, Georgios I. Karras, Susan Lindquist
Cell. Author manuscript; available in PMC 2014 Jan 17.
Published in final edited form as: Cell. 2012 Aug 31; 150(5): 987–1001. doi: 10.1016/j.cell.2012.06.047
PMCID:
PMC3894786
AbstractArticlePDF–5.0M

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