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Select item 50650051.

Crystal structure and interaction studies of the human FBxo3 ApaG domain

Troy C. Krzysiak, Bill B. Chen, Travis Lear, Rama K. Mallampalli, Angela M. Gronenborn

FEBS J. Author manuscript; available in PMC 2016 Oct 14.

Published in final edited form as: FEBS J. 2016 Jun; 283(11): 2091–2101. Published online 2016 Apr 22. doi: 10.1111/febs.13721

PMCID:: PMC5065005

Abstract Article PDF–1.0M

Select item 72617202.

Tumor Necrosis Factor Alpha Regulates Skeletal Myogenesis by Inhibiting SP1 Interaction with cis-Acting Regulatory Elements within the Fbxl2 Gene Promoter

Michael E. O’Brien, James Londino, Marcus McGinnis, Nathaniel Weathington, Jessica Adair, Tomeka Suber, Valerian Kagan, Kong Chen, Chunbin Zou, Bill Chen, Jessica Bon, Rama K. Mallampalli

Mol Cell Biol. 2020 Jun; 40(12): e00040-20. Prepublished online 2020 Mar 23. Published online 2020 May 28. doi: 10.1128/MCB.00040-20

PMCID:: PMC7261720

Abstract Article PDF–3.8M

Select item 74943443.

FUNDC1 interacts with FBXL2 to govern mitochondrial integrity and cardiac function through an IP3R3-dependent manner in obesity

Jun Ren, Mingming Sun, Hao Zhou, Amir Ajoolabady, Yuan Zhou, Jun Tao, James R. Sowers, Yingmei Zhang

Sci Adv. 2020 Sep; 6(38): eabc8561. Published online 2020 Sep 16. doi: 10.1126/sciadv.abc8561

PMCID:: PMC7494344

Abstract Article PDF–9.5M

Select item 66210504.

FBL2 Regulates Amyloid Precursor Protein (APP) Metabolism by Promoting Ubiquitination-Dependent APP Degradation and Inhibition of APP Endocytosis

Tomomichi Watanabe, Yukiko Hikichi, Antje Willuweit, Yasushi Shintani, Takashi Horiguchi

J Neurosci. 2012 Mar 7; 32(10): 3352–3365. doi: 10.1523/JNEUROSCI.5659-11.2012

PMCID:: PMC6621050

Abstract Article PDF–1.9M

Select item 45050575.

Lipopolysaccharide Primes the NALP3 Inflammasome by Inhibiting Its Ubiquitination and Degradation Mediated by the SCF^FBXL2 E3 Ligase

SeungHye Han, Travis B. Lear, Jacob A. Jerome, Shristi Rajbhandari, Courtney A. Snavely, Dexter L. Gulick, Kevin F. Gibson, Chunbin Zou, Bill B. Chen, Rama K. Mallampalli

J Biol Chem. 2015 Jul 17; 290(29): 18124–18133. Published online 2015 Jun 2. doi: 10.1074/jbc.M115.645549

PMCID:: PMC4505057

Abstract Article PDF–1.4M

Select item 32669586.

F box protein FBXL2 exerts human lung tumor suppressor-like activity by ubiquitin-mediated degradation of cyclin D3 resulting in cell cycle arrest

Bill B. Chen, Jennifer R. Glasser, Tiffany A. Coon, Rama K. Mallampalli

Oncogene. Author manuscript; available in PMC 2012 Nov 17.

Published in final edited form as: Oncogene. 2012 May 17; 31(20): 2566–2579. Published online 2011 Oct 24. doi: 10.1038/onc.2011.432

PMCID:: PMC3266958

Abstract Article PDF–1.3M

Select item 99883757.

Palmitoylation and PDE6δ regulate membrane-compartment-specific substrate ubiquitylation and degradation

David Liang, Liping Jiang, Sameer Ahmed Bhat, Sonia Missiroli, Mariasole Perrone, Angela Lauriola, Ritika Adhikari, Anish Gudur, Zahra Vasi, Ian Ahearn, Daniele Guardavaccaro, Carlotta Giorgi, Mark Philips, Shafi Kuchay

Cell Rep. Author manuscript; available in PMC 2023 Mar 6.

Published in final edited form as: Cell Rep. 2023 Jan 31; 42(1): 111999. Published online 2023 Jan 19. doi: 10.1016/j.celrep.2023.111999

PMCID:: PMC9988375

Abstract Article PDF–2.1M

Select item 22590048.

Human Butyrate-Induced Transcript 1 Interacts with Hepatitis C Virus NS5A and Regulates Viral Replication

Shuhei Taguwa, Toru Okamoto, Takayuki Abe, Yoshio Mori, Tetsuro Suzuki, Kohji Moriishi, Yoshiharu Matsuura

J Virol. 2008 Mar; 82(6): 2631–2641. Published online 2007 Dec 26. doi: 10.1128/JVI.02153-07

PMCID:: PMC2259004

Abstract Article PDF–804K

Select item 37634339.

Skp-cullin-F box E3 ligase component FBXL2 ubiquitinates Aurora B to inhibit tumorigenesis

B B Chen, J R Glasser, T A Coon, R K Mallampalli

Cell Death Dis. 2013 Aug; 4(8): e759. Published online 2013 Aug 8. doi: 10.1038/cddis.2013.271

PMCID:: PMC3763433

Abstract Article PDF–3.1M

Select item 850550910.

FBXL2 counteracts Grp94 to destabilize EGFR and inhibit EGFR-driven NSCLC growth

Mengmeng Niu, Jing Xu, Yang Liu, Yuhuang Li, Tao He, Liangping Ding, Yajun He, Yong Yi, Fengtian Li, Rongtian Guo, Ya Gao, Rui Li, Luping Li, Mengyuan Fu, Qingyong Hu, Yangkun Luo, Chunyan Zhang, Kewei Qin, Jianqiao Yi, Shuhan Yu, Jian Yang, Hu Chen, Liang Wang, Zhonghan Li, Biao Dong, Shiqian Qi, Liang Ouyang, Yujun Zhang, Yang Cao, Zhi-Xiong Jim Xiao

Nat Commun. 2021; 12: 5919. Published online 2021 Oct 11. doi: 10.1038/s41467-021-26222-x

PMCID:: PMC8505509

Abstract Article PDF–7.1M

Select item 359426711.

Calmodulin protects Aurora B on the midbody to regulate the fidelity of cytokinesis

Rama K. Mallampalli, Jennifer R. Glasser, Tiffany A. Coon, Bill B. Chen

Cell Cycle. 2013 Feb 15; 12(4): 663–673. doi: 10.4161/cc.23586

PMCID:: PMC3594267

Abstract Article PDF–4.2M

Select item 332187312.

F-box protein FBXL2 targets cyclin D2 for ubiquitination and degradation to inhibit leukemic cell proliferation

Bill B. Chen, Jennifer R. Glasser, Tiffany A. Coon, Chunbin Zou, Hannah L. Miller, Moon Fenton, John F. McDyer, Michael Boyiadzis, Rama K. Mallampalli

Blood. 2012 Mar 29; 119(13): 3132–3141. Prepublished online 2012 Feb 8. doi: 10.1182/blood-2011-06-358911

PMCID:: PMC3321873

Abstract Article

Select item 195936813.

Reliance of Host Cholesterol Metabolic Pathways for the Life Cycle of Hepatitis C Virus

Jin Ye

PLoS Pathog. 2007 Aug; 3(8): e108. Published online 2007 Aug 31. doi: 10.1371/journal.ppat.0030108

PMCID:: PMC1959368

Abstract Article PDF–214K

Select item 386586614.

FBXL2- and PTPL1-mediated degradation of p110-free p85β regulatory subunit controls the PI(3)K signalling cascade

Shafi Kuchay, Shanshan Duan, Emily Schenkein, Angelo Peschiaroli, Anita Saraf, Laurence Florens, Michael P. Washburn, Michele Pagano

Nat Cell Biol. Author manuscript; available in PMC 2013 Dec 17.

Published in final edited form as: Nat Cell Biol. 2013 May; 15(5): 10.1038/ncb2731. Published online 2013 Apr 21. doi: 10.1038/ncb2731

PMCID:: PMC3865866

Abstract Article PDF–2.2M

Select item 562796915.

PTEN counteracts FBXL2 to promote IP3R3– and Ca²⁺–mediated apoptosis limiting tumour growth

Shafi Kuchay, Carlotta Giorgi, Daniele Simoneschi, julia Pagan, Sonia Missiroli, Anita Saraf, Laurence Florens, Michael P. Washburn, Ana Collazo-Lorduy, Mireia Castillo-Martin, Carlos Cordon-Cardo, Said M. Sebti, Paolo Pinton, Michele Pagano

Nature. Author manuscript; available in PMC 2017 Oct 4.

Published in final edited form as: Nature. 2017 Jun 22; 546(7659): 554–558. Published online 2017 Jun 14. doi: 10.1038/nature22965

PMCID:: PMC5627969

Abstract Article PDF–1.3M

Select item 862978516.

Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter

Dolores Piniella, Elena Martínez-Blanco, David Bartolomé-Martín, Ana B. Sanz-Martos, Francisco Zafra

Cell Mol Life Sci. 2021 Dec; 78(23): 7733–7756. Published online 2021 Oct 28. doi: 10.1007/s00018-021-03998-1

PMCID:: PMC8629785

Abstract Article PDF–10M

Select item 398146817.

Parallel SCF Adaptor Capture Proteomics Reveals a Role for SCF^FBXL17 in NRF2 Activation via BACH1 Repressor Turnover

Meng-Kwang Marcus Tan, Hui-Jun Lim, Eric J. Bennett, Yang Shi, J. Wade Harper

Mol Cell. Author manuscript; available in PMC 2014 Oct 10.

Published in final edited form as: Mol Cell. 2013 Oct 10; 52(1): 9–24. Published online 2013 Sep 12. doi: 10.1016/j.molcel.2013.08.018

PMCID:: PMC3981468

Abstract Article PDF–5.8M

Select item 1015617518.

Systemwide disassembly and assembly of SCF ubiquitin ligase complexes

Kheewoong Baek, Daniel C. Scott, Lukas T. Henneberg, Moeko T. King, Matthias Mann, Brenda A. Schulman

Cell. 2023 Apr 27; 186(9): 1895–1911.e21. doi: 10.1016/j.cell.2023.02.035

Correction in:: Cell. 2023 May 25; 186(11): 2492.

PMCID:: PMC10156175

Abstract Article

Select item 571159519.

Composition and regulation of the cellular repertoire of SCF ubiquitin ligases

Justin M. Reitsma, Xing Liu, Kurt M. Reichermeier, Annie Moradian, Michael J. Sweredoski, Sonja Hess, Raymond J. Deshaies

Cell. Author manuscript; available in PMC 2018 Nov 30.

Published in final edited form as: Cell. 2017 Nov 30; 171(6): 1326–1339.e14. Published online 2017 Nov 2. doi: 10.1016/j.cell.2017.10.016

PMCID:: PMC5711595

Abstract Article PDF–2.4M

Select item 410454420.

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways

Mikko Taipale, George Tucker, Jian Peng, Irina Krykbaeva, Zhen-Yuan Lin, Brett Larsen, Hyungwon Choi, Bonnie Berger, Anne-Claude Gingras, Susan Lindquist

Cell. Author manuscript; available in PMC 2015 Jul 17.

Published in final edited form as: Cell. 2014 Jul 17; 158(2): 434–448. doi: 10.1016/j.cell.2014.05.039