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Items: 18

Select item 66912621.

Downregulation of miR-98 contributes to hypoxic pulmonary hypertension by targeting ALK1

Qingling Li, Xincan Zhou, Xianghui Zhou

Mol Med Rep. 2019 Sep; 20(3): 2167–2176. Published online 2019 Jul 9. doi: 10.3892/mmr.2019.10482

PMCID:: PMC6691262

Abstract Article PDF–1.3M

Select item 62756502.

The role of Alk-1 and Alk-5 in the mechanosensing of chondrocytes

Patricia Sanz-Ramos, Javier Dotor, Iñigo Izal-Azcárate

Cell Mol Biol Lett. 2014 Dec; 19(4): 659–674. Published online 2014 Nov 25. doi: 10.2478/s11658-014-0220-6

PMCID:: PMC6275650

Summary PDF–1.9M

Select item 62079183.

Functional Expression of Organic Anion Transporting Polypeptide 1a4 Is Regulated by Transforming Growth Factor-β/Activin Receptor-like Kinase 1 Signaling at the Blood-Brain Barrier

Wazir Abdullahi, Hrvoje Brzica, Nicholas A. Hirsch, Bianca G. Reilly, Patrick T. Ronaldson

Mol Pharmacol. 2018 Dec; 94(6): 1321–1333. Published online 2018 Dec. doi: 10.1124/mol.118.112912

PMCID:: PMC6207918

Abstract Article PDF–885K

Select item 45036014.

Functional and splicing defect analysis of 23 ACVRL1 mutations in a cohort of patients affected by Hereditary Hemorrhagic Telangiectasia

Ferdos Alaa el Din, Sylvie Patri, Vincent Thoreau, Montserrat Rodriguez-Ballesteros, Eva Hamade, Sabine Bailly, Brigitte Gilbert-Dussardier, Raghida Abou Merhi, Alain Kitzis

PLoS One. 2015; 10(7): e0132111. Published online 2015 Jul 15. doi: 10.1371/journal.pone.0132111

PMCID:: PMC4503601

Abstract Article PDF–2.5M

Select item 28866135.

Adenosine protected against pulmonary edema through transporter- and receptor A₂-mediated endothelial barrier enhancement

Qing Lu, Elizabeth O. Harrington, Julie Newton, Brian Casserly, Gregory Radin, Rod Warburton, Yang Zhou, Michael R. Blackburn, Sharon Rounds

Am J Physiol Lung Cell Mol Physiol. 2010 Jun; 298(6): L755–L767. Published online 2010 Mar 12. doi: 10.1152/ajplung.00330.2009

PMCID:: PMC2886613

Abstract Article

Select item 21718516.

TGF-β1 activates two distinct type I receptors in neurons: implications for neuronal NF-κB signaling

Hans-Georg König, Donat Kögel, Abdelhaq Rami, Jochen H.M. Prehn

J Cell Biol. 2005 Mar 28; 168(7): 1077–1086. doi: 10.1083/jcb.200407027

PMCID:: PMC2171851

Abstract Article PDF–2.9M

Select item 17353427.

Molecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia

R Harrison, J Flanagan, M Sankelo, S Abdalla, J Rowell, R Machado, C Elliott, I Robbins, H Olschewski, V McLaughlin, E Gruenig, F Kermeen, T Laitinen, N Morrell, R Trembath

J Med Genet. 2003 Dec; 40(12): 865–871. doi: 10.1136/jmg.40.12.865

Correction in:: J Med Genet. 2004 Jul; 41(7): 576.

PMCID:: PMC1735342

Summary PDF–532K

Select item 27750038.

Casein kinase 2β as a novel enhancer of activin-like receptor-1 signaling

Nam Y. Lee, John C. Haney, Julie Sogani, Gerard C. Blobe

FASEB J. 2009 Nov; 23(11): 3712–3721. doi: 10.1096/fj.09-131607

PMCID:: PMC2775003

Abstract Article

Select item 22008479.

ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2

Sung O. Park, Young Jae Lee, Tsugio Seki, Kwon-Ho Hong, Naime Fliess, Zhigang Jiang, Alice Park, Xiaofang Wu, Vesa Kaartinen, Beth L. Roman, S. Paul Oh

Blood. 2008 Jan 15; 111(2): 633–642. Prepublished online 2007 Oct 2. doi: 10.1182/blood-2007-08-107359

PMCID:: PMC2200847

Abstract Article

Select item 1597910.

Activin receptor-like kinase 1 modulates transforming growth factor-β1 signaling in the regulation of angiogenesis

S. Paul Oh, Tsugio Seki, Kendrick A. Goss, Takeshi Imamura, Youngsuk Yi, Patricia K. Donahoe, Li Li, Kohei Miyazono, Peter ten Dijke, Seongjin Kim, En Li

Proc Natl Acad Sci U S A. 2000 Mar 14; 97(6): 2626–2631. doi: 10.1073/pnas.97.6.2626

PMCID:: PMC15979

Abstract Article PDF–469K

Select item 283076711.

ALK1 signaling regulates early postnatal lymphatic vessel development

Kyle Niessen, Gu Zhang, John Brady Ridgway, Hao Chen, Minhong Yan

Blood. 2010 Feb 25; 115(8): 1654–1661. Prepublished online 2009 Nov 10. doi: 10.1182/blood-2009-07-235655

PMCID:: PMC2830767

Abstract Article

Select item 270887612.

Bone Morphogenetic Protein (BMP) and Activin Type II Receptors Balance BMP9 Signals Mediated by Activin Receptor-like Kinase-1 in Human Pulmonary Artery Endothelial Cells

Paul D. Upton, Rachel J. Davies, Richard C. Trembath, Nicholas W. Morrell

J Biol Chem. 2009 Jun 5; 284(23): 15794–15804. Published online 2009 Apr 14. doi: 10.1074/jbc.M109.002881

PMCID:: PMC2708876

Abstract Article PDF–811K

Select item 383640213.

LRG1 promotes angiogenesis by modulating endothelial TGFß signalling

Xiaomeng Wang, Sabu Abraham, Jenny A.G. McKenzie, Natasha Jeffs, Matthew Swire, Vineeta B. Tripathi, Ulrich F.O. Luhmann, Clemens A.K. Lange, Zhenhua Zhai, Helen M. Arthur, James Bainbridge, Stephen E. Moss, John Greenwood

Nature. Author manuscript; available in PMC 2014 Jan 18.

Published in final edited form as: Nature. 2013 Jul 18; 499(7458): 10.1038/nature12345. doi: 10.1038/nature12345

PMCID:: PMC3836402

Abstract Article PDF–3.1M

Select item 2978714.

RefSeq and LocusLink: NCBI gene-centered resources

Kim D. Pruitt, Donna R. Maglott

Nucleic Acids Res. 2001 Jan 1; 29(1): 137–140. doi: 10.1093/nar/29.1.137

PMCID:: PMC29787

Abstract Article PDF–108K

Select item 340974215.

Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis

Satoshi Somekawa, Keiichi Imagawa, Hisaki Hayashi, Masahide Sakabe, Tomoko Ioka, Genki E. Sato, Ken Inada, Takaaki Iwamoto, Toshio Mori, Shiro Uemura, Osamu Nakagawa, Yoshihiko Saito

Proc Natl Acad Sci U S A. 2012 Jul 24; 109(30): 12064–12069. Published online 2012 Jul 10. doi: 10.1073/pnas.1207210109