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Select item 56014591.

Oligodendroglial excitability mediated by glutamatergic inputs and Nav1.2 activation

Emmanuelle Berret, Tara Barron, Jie Xu, Emily Debner, Eun Jung Kim, Jun Hee Kim

Nat Commun. 2017; 8: 557. Published online 2017 Sep 15. doi: 10.1038/s41467-017-00688-0

PMCID:: PMC5601459

Abstract Article PDF–11M

Select item 55037522.

Calcium Triggers Reversal of Calmodulin on Nested Anti-Parallel Sites in the IQ Motif of the Neuronal Voltage-Dependent Sodium Channel Na_V1.2

Liam Hovey, C. Andrew Fowler, Ryan Mahling, Zesen Lin, Mark Stephen Miller, Dagan C. Marx, Jesse B. Yoder, Elaine H. Kim, Kristin M. Tefft, Brett C. Waite, Michael D. Feldkamp, Liping Yu, Madeline A. Shea

Biophys Chem. Author manuscript; available in PMC 2018 May 1.

Published in final edited form as: Biophys Chem. 2017 May; 224: 1–19. Published online 2017 Mar 9. doi: 10.1016/j.bpc.2017.02.006

PMCID:: PMC5503752

Abstract Article PDF–1.5M

Select item 52838323.

SUMOylation of Na_V1.2 channels mediates the early response to acute hypoxia in central neurons

Leigh D Plant, Jeremy D Marks, Steve AN Goldstein

eLife. 2016; 5: e20054. Published online 2016 Dec 28. doi: 10.7554/eLife.20054

PMCID:: PMC5283832

Abstract Article PDF–3.2M

Select item 43361634.

The Na_v1.2 channel is regulated by GSK3

Thomas F. James, Miroslav N. Nenov, Norelle C. Wildburger, Cheryl Lichti, Jonathan Luisi, Fernanda Vergara, Neli I. Panova-Electronova, Carol L. Nilsson, Jai Rudra, Thomas A. Green, Demetrio Labate, Fernanda Laezza

Biochim Biophys Acta. Author manuscript; available in PMC 2016 Apr 1.

Published in final edited form as: Biochim Biophys Acta. 2015 Apr; 1850(4): 832–844. Published online 2015 Jan 20. doi: 10.1016/j.bbagen.2015.01.011

PMCID:: PMC4336163

Abstract Article PDF–1.9M

Select item 41408935.

Reciprocal Changes in Phosphorylation and Methylation of Mammalian Brain Sodium Channels in Response to Seizures

Je-Hyun Baek, Moran Rubinstein, Todd Scheuer, James S. Trimmer

J Biol Chem. 2014 May 30; 289(22): 15363–15373. Published online 2014 Apr 15. doi: 10.1074/jbc.M114.562785

PMCID:: PMC4140893

Abstract Article PDF–1.2M

Select item 32501916.

Palmitoylation influences the function and pharmacology of sodium channels

Frank Bosmans, Mirela Milescu, Kenton J. Swartz

Proc Natl Acad Sci U S A. 2011 Dec 13; 108(50): 20213–20218. Published online 2011 Nov 28. doi: 10.1073/pnas.1108497108

PMCID:: PMC3250191

Abstract Article PDF–522K

Select item 31909247.

Structure-Function Map of the Receptor Site for β-Scorpion Toxins in Domain II of Voltage-gated Sodium Channels

Joel Z. Zhang, Vladimir Yarov-Yarovoy, Todd Scheuer, Izhar Karbat, Lior Cohen, Dalia Gordon, Michael Gurevitz, William A. Catterall

J Biol Chem. 2011 Sep 23; 286(38): 33641–33651. Published online 2011 Jul 27. doi: 10.1074/jbc.M111.282509

PMCID:: PMC3190924

Abstract Article PDF–2.2M

Select item 28787378.

Synergistic and Antagonistic Interactions between Tetrodotoxin and μ-Conotoxin in Blocking Voltage-gated Sodium Channels

Min-Min Zhang, Jeff R. McArthur, Layla Azam, Grzegorz Bulaj, Baldomero M Olivera, Robert J French, Doju Yoshikami

Channels (Austin) Author manuscript; available in PMC 2010 May 31.

Published in final edited form as: Channels (Austin). 2009 Jan–Feb; 3(1): 32–38. Published online 2009 Jan 25. doi: 10.4161/chan.3.1.7500

PMCID:: PMC2878737

Abstract Article PDF–659K

Select item 27996819.

Calpain Mediates Proteolysis of the Voltage-Gated Sodium Channel α-Subunit

Catherine R. von Reyn, Jennifer M. Spaethling, Mahlet N. Mesfin, Marek Ma, Robert W. Neumar, Douglas H. Smith, Robert Siman, David F. Meaney

J Neurosci. 2009 Aug 19; 29(33): 10350–10356. doi: 10.1523/JNEUROSCI.2339-09.2009

PMCID:: PMC2799681

Abstract Article PDF–893K

Select item 275299210.

New Insights in the Contribution of Voltage-Gated Na_v Channels to Rat Aorta Contraction

Aurélie Fort, Magali Cordaillat, Catherine Thollon, Guillermo Salazar, Ilana Mechaly, Nicole Villeneuve, Jean-Paul Vilaine, Sylvain Richard, Anne Virsolvy

PLoS One. 2009; 4(10): e7360. Published online 2009 Oct 7. doi: 10.1371/journal.pone.0007360

PMCID:: PMC2752992

Abstract Article PDF–438K

Select item 182928411.

Dopamine modulation of neuronal Na⁺ channels requires binding of A kinase-anchoring protein 15and PKA by a modified leucine zipper motif

W. Preston Few, Todd Scheuer, William A. Catterall

Proc Natl Acad Sci U S A. 2007 Mar 20; 104(12): 5187–5192. Published online 2007 Mar 14. doi: 10.1073/pnas.0611619104

PMCID:: PMC1829284

Abstract Article PDF–604K

Select item 730622612.

Altered hippocampal replay is associated with memory impairment in mice heterozygous for the Scn2a gene

Steven J. Middleton, Emily M. Kneller, Shuo Chen, Ikuo Ogiwara, Mauricio Montal, Kazuhiro Yamakawa, Thomas J. McHugh

Nat Neurosci. Author manuscript; available in PMC 2020 Jun 21.

Published in final edited form as: Nat Neurosci. 2018 Jul; 21(7): 996–1003. Published online 2018 Jun 4. doi: 10.1038/s41593-018-0163-8

PMCID:: PMC7306226

Abstract Article PDF–837K

Select item 667463713.

Effects in Neocortical Neurons of Mutations of the Na_v1.2 Na⁺ Channel causing Benign Familial Neonatal-Infantile Seizures

Paolo Scalmani, Raffaella Rusconi, Elena Armatura, Federico Zara, Giuliano Avanzini, Silvana Franceschetti, Massimo Mantegazza

J Neurosci. 2006 Oct 4; 26(40): 10100–10109. doi: 10.1523/JNEUROSCI.2476-06.2006

PMCID:: PMC6674637

Abstract Article PDF–555K

Select item 592736814.

Sodium channel subtypes are differentially localized to pre- and post-synaptic sites in rat hippocampus

Kenneth W. Johnson, Karl F. Herold, Teresa A. Milner, Hugh C. Hemmings, Jr., Jimcy Platholi

J Comp Neurol. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: J Comp Neurol. 2017 Nov 1; 525(16): 3563–3578. Published online 2017 Aug 11. doi: 10.1002/cne.24291

PMCID:: PMC5927368

Abstract Article PDF–1.4M

Select item 579678515.

Opposing effects on Na_V1.2 function underlie differences between SCN2A variants observed in individuals with autism spectrum disorder or infantile seizures

Roy Ben-Shalom, Caroline M. Keeshen, Kiara N. Berrios, Joon Y. An, Stephan J. Sanders, Kevin J. Bender

Biol Psychiatry. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Biol Psychiatry. 2017 Aug 1; 82(3): 224–232. Published online 2017 Jan 27. doi: 10.1016/j.biopsych.2017.01.009

PMCID:: PMC5796785

Abstract Article PDF–1.0M

Select item 442440016.

Quantitative Proteomics Reveals Protein–Protein Interactions with Fibroblast Growth Factor 12 as a Component of the Voltage-Gated Sodium Channel 1.2 (Nav1.2) Macromolecular Complex in Mammalian Brain

Norelle C. Wildburger, Syed R. Ali, Wei-Chun J. Hsu, Alexander S. Shavkunov, Miroslav N. Nenov, Cheryl F. Lichti, Richard D. LeDuc, Ekaterina Mostovenko, Neli I. Panova-Elektronova, Mark R. Emmett, Carol L. Nilsson, Fernanda Laezza

Mol Cell Proteomics. 2015 May; 14(5): 1288–1300. Published online 2015 Feb 27. doi: 10.1074/mcp.M114.040055

PMCID:: PMC4424400

Abstract Article PDF–3.1M

Select item 362581017.

Effective contractile response to voltage-gated Na⁺ channels revealed by a channel activator

W.-S. Vanessa Ho, Alison J. Davis, Preet S. Chadha, Iain A. Greenwood

Am J Physiol Cell Physiol. 2013 Apr 15; 304(8): C739–C747. Published online 2013 Jan 30. doi: 10.1152/ajpcell.00164.2012

PMCID:: PMC3625810

Abstract Article

Select item 290710518.

µ-Conotoxin KIIIA Derivatives with Divergent Affinities versus Efficacies in Blocking Voltage-gated Sodium Channels

Min-Min Zhang, Tiffany S. Han, Baldomero M. Olivera, Grzegorz Bulaj, Doju Yoshikami

Biochemistry. Author manuscript; available in PMC 2011 Jun 15.

Published in final edited form as: Biochemistry. 2010 Jun 15; 49(23): 4804–4812. doi: 10.1021/bi100207k

PMCID:: PMC2907105

Abstract Article PDF–675K

Select item 672482419.

Sodium Currents in Medullary Neurons Isolated from the Pre-Bötzinger Complex Region

Krzysztof Ptak, Greer G. Zummo, George F. Alheid, Tatiana Tkatch, D. James Surmeier, Donald R. McCrimmon

J Neurosci. 2005 May 25; 25(21): 5159–5170. doi: 10.1523/JNEUROSCI.4238-04.2005

PMCID:: PMC6724824

Abstract Article PDF–496K

Select item 453048120.

MicroRNA-9 induces defective trafficking of Nav1.1 and Nav1.2 by targeting Navβ2 protein coding region in rat with chronic brain hypoperfusion

Li-Hua Sun, Mei-Ling Yan, Xue-Ling Hu, Li-Wei Peng, Hui Che, Ya-Nan Bao, Fei Guo, Tong Liu, Xin Chen, Rong Zhang, Tao Ban, Ning Wang, Huai-Lei Liu, Xu Hou, Jing Ai

Mol Neurodegener. 2015; 10: 36. Published online 2015 Aug 11. doi: 10.1186/s13024-015-0032-9