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Items: 1 to 20 of 51

1.
The Ubiquitin Specific Protease USP18 Promotes Lipolysis, Fatty Acid Oxidation and Lung Cancer Growth
Xi Liu, Yun Lu, Zibo Chen, Xiuxia Liu, Weiguo Hu, Lin Zheng, Yulong Chen, Jonathan M. Kurie, Mi Shi, Lisa Maria Mustachio, Thorkell Adresson, Stephen Fox, Jason Roszik, Masanori Kawakami, Sarah Freemantle, Ethan Dmitrovsky
Mol Cancer Res. Author manuscript; available in PMC 2021 Oct 1.
Published in final edited form as: Mol Cancer Res. 2021 Apr; 19(4): 667–677. Published online 2020 Dec 30. doi: 10.1158/1541-7786.MCR-20-0579
PMCID:
PMC8026529
AbstractArticlePDF–1.2M
2.
Mice null for the deubiquitinase USP18 spontaneously develop leiomyosarcomas
Fadzai Chinyengetere, David J. Sekula, Yun Lu, Andrew J. Giustini, Aarti Sanglikar, Masanori Kawakami, Tian Ma, Sandra S. Burkett, Burton L. Eisenberg, Wendy A. Wells, Paul J. Hoopes, Elizabeth G. Demicco, Alexander J Lazar, Keila E. Torres, Vincent Memoli, Sarah J. Freemantle, Ethan Dmitrovsky
BMC Cancer. 2015; 15: 886. Published online 2015 Nov 10. doi: 10.1186/s12885-015-1883-8
PMCID:
PMC4640382
AbstractArticlePDF–1.4M
3.
Microarray analysis reveals that Type I interferon strongly increases the expression of immune-response related genes in Ubp43 (Usp18) deficient macrophages
Weiguo Zou, Jung-Hwan Kim, Adedayo Handidu, Xiang Li, Keun Il Kim, Ming Yan, Jun Li, Dong-Er Zhang
Biochem Biophys Res Commun. Author manuscript; available in PMC 2008 Apr 27.
Published in final edited form as: Biochem Biophys Res Commun. 2007 Apr 27; 356(1): 193–199. Published online 2007 Feb 28. doi: 10.1016/j.bbrc.2007.02.101
PMCID:
PMC1868545
AbstractArticlePDF–879K
4.
Protein ISGylation modulates the JAK-STAT signaling pathway
Oxana A. Malakhova, Ming Yan, Michael P. Malakhov, Youzhong Yuan, Kenneth J. Ritchie, Keun Il Kim, Luke F. Peterson, Ke Shuai, Dong-Er Zhang
Genes Dev. 2003 Feb 15; 17(4): 455–460. doi: 10.1101/gad.1056303
PMCID:
PMC195994
AbstractArticlePDF–234K
5.
A Novel Ubiquitin-Specific Protease, UBP43, Cloned from Leukemia Fusion Protein AML1-ETO-Expressing Mice, Functions in Hematopoietic Cell Differentiation
Li-Qin Liu, Robert Ilaria, Jr., Paul D. Kingsley, Atsushi Iwama, Richard A. van Etten, James Palis, Dong-Er Zhang
Mol Cell Biol. 1999 Apr; 19(4): 3029–3038. doi: 10.1128/mcb.19.4.3029
PMCID:
PMC84097
AbstractArticlePDF–4.4M
6.
The in vivo ISGylome links ISG15 to metabolic pathways and autophagy upon Listeria monocytogenes infection
Yifeng Zhang, Fabien Thery, Nicholas C. Wu, Emma K. Luhmann, Olivier Dussurget, Mariko Foecke, Clara Bredow, Daniel Jiménez-Fernández, Kevin Leandro, Antje Beling, Klaus-Peter Knobeloch, Francis Impens, Pascale Cossart, Lilliana Radoshevich
Nat Commun. 2019; 10: 5383. Published online 2019 Nov 26. doi: 10.1038/s41467-019-13393-x
PMCID:
PMC6879477
AbstractArticlePDF–3.3M
7.
Loss of USP18 in microglia induces white matter pathology
Marius Schwabenland, Omar Mossad, Adam G. Peres, Franziska Kessler, Feres Jose Mocayar Maron, Laura-Adela Harsan, Thomas Bienert, Dominik von Elverfeldt, Klaus-Peter Knobeloch, Ori Staszewski, Frank L. Heppner, Marije E. C. Meuwissen, Grazia M. S. Mancini, Marco Prinz, Thomas Blank
Acta Neuropathol Commun. 2019; 7: 106. Published online 2019 Jul 4. doi: 10.1186/s40478-019-0757-8
PMCID:
PMC6610953
ArticlePDF–8.2M
8.
Deubiquitinase USP18 Loss Mislocalizes and Destabilizes KRAS in Lung Cancer
Lisa Maria Mustachio, Yun Lu, Laura J. Tafe, Vincent Memoli, Jaime Rodriguez-Canales, Barbara Mino, Pamela Andrea Villalobos, Ignacio Wistuba, Hiroyuki Katayama, Samir M. Hanash, Jason Roszik, Masanori Kawakami, Kwang-jin Cho, John F. Hancock, Fadzai Chinyengetere, Shanhu Hu, Xi Liu, Sarah J. Freemantle, Ethan Dmitrovsky
Mol Cancer Res. Author manuscript; available in PMC 2018 Jul 1.
Published in final edited form as: Mol Cancer Res. 2017 Jul; 15(7): 905–914. Published online 2017 Feb 27. doi: 10.1158/1541-7786.MCR-16-0369
PMCID:
PMC5635999
AbstractArticlePDF–1.1M
9.
Lipopolysaccharide and Tumor Necrosis Factor Alpha Inhibit Interferon Signaling in Hepatocytes by Increasing Ubiquitin-Like Protease 18 (USP18) Expression
Sonya A. MacParland, Xue-Zhong Ma, Limin Chen, Ramzi Khattar, Vera Cherepanov, Markus Selzner, Jordan J. Feld, Nazia Selzner, Ian D. McGilvray
J Virol. 2016 Jun 15; 90(12): 5549–5560. Prepublished online 2016 Mar 23. Published online 2016 May 27. doi: 10.1128/JVI.02557-15
PMCID:
PMC4886784
AbstractArticlePDF–1.7M
10.
Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance
Lars Ketscher, Ronny Hannß, David J. Morales, Anja Basters, Susana Guerra, Tobias Goldmann, Annika Hausmann, Marco Prinz, Ronald Naumann, Andrew Pekosz, Olaf Utermöhlen, Deborah J. Lenschow, Klaus-Peter Knobeloch
Proc Natl Acad Sci U S A. 2015 Feb 3; 112(5): 1577–1582. Published online 2015 Jan 20. doi: 10.1073/pnas.1412881112
PMCID:
PMC4321242
AbstractArticlePDF–1.0M
11.
Contribution of increased ISG15, ISGylation and deregulated Type I IFN signaling in Usp18 mutant mice during the course of bacterial infections
Shauna M. Dauphinee, Etienne Richer, Megan M. Eva, Fiona McIntosh, Marilène Paquet, David Dangoor, Christoph Burkart, Dong-Er Zhang, Samantha Gruenheid, Philippe Gros, Marcel Behr, Danielle Malo
Genes Immun. Author manuscript; available in PMC 2015 Jan 1.
Published in final edited form as: Genes Immun. 2014 Jul-Aug; 15(5): 282–292. Published online 2014 May 8. doi: 10.1038/gene.2014.17
PMCID:
PMC4111656
AbstractArticlePDF–1.0M
12.
Protein Interferon-Stimulated Gene 15 Conjugation Delays but Does Not Overcome Coronavirus Proliferation in a Model of Fulminant Hepatitis
Xue-Zhong Ma, Agata Bartczak, Jianhua Zhang, Wei He, Itay Shalev, David Smil, Limin Chen, Jim Phillips, Jordan J. Feld, Nazia Selzner, Gary Levy, Ian McGilvray
J Virol. 2014 Jun; 88(11): 6195–6204. doi: 10.1128/JVI.03801-13
PMCID:
PMC4093886
AbstractArticlePDF–1.3M
13.
USP18 is crucial for IFN-γ-mediated inhibition of B16 melanoma tumorigenesis and antitumor immunity
Bangxing Hong, Haiyan Li, Yong Lu, Mingjun Zhang, Yuhuan Zheng, Jianfei Qian, Qing Yi
Mol Cancer. 2014; 13: 132. Published online 2014 May 31. doi: 10.1186/1476-4598-13-132
PMCID:
PMC4057584
AbstractArticlePDF–3.5M
14.
Ubiquitin specific protease 18 (Usp18) is a WT1 transcriptional target
Mohammad Shahidul Makki, E. Cristy Ruteshouser, Vicki Huff
Exp Cell Res. Author manuscript; available in PMC 2014 Mar 10.
Published in final edited form as: Exp Cell Res. 2013 Mar 10; 319(5): 612–622. Published online 2013 Jan 2. doi: 10.1016/j.yexcr.2012.12.021
PMCID:
PMC3791519
AbstractArticlePDF–3.3M
15.
The mitochondrial pathway and reactive oxygen species are critical contributors to interferon-α/β-mediated apoptosis in Ubp43-deficient hematopoietic cells
Hwa Young Yim, Young Yang, Jong-Seok Lim, Myeong Seok Lee, Dong-Er Zhang, Keun Il Kim
Biochem Biophys Res Commun. Author manuscript; available in PMC 2013 Jun 29.
Published in final edited form as: Biochem Biophys Res Commun. 2012 Jun 29; 423(2): 436–440. Published online 2012 Jun 5. doi: 10.1016/j.bbrc.2012.05.154
PMCID:
PMC3389127
AbstractArticlePDF–1.1M
16.
Usp18 promotes conventional CD11b+ dendritic cell development
Xiu-Li Cong, Miao-Chia Lo, Brian A Reuter, Ming Yan, Jun-Bao Fan, Dong-Er Zhang
J Immunol. Author manuscript; available in PMC 2013 May 15.
Published in final edited form as: J Immunol. 2012 May 15; 188(10): 4776–4781. Published online 2012 Apr 9. doi: 10.4049/jimmunol.1101609
PMCID:
PMC3345079
AbstractArticlePDF–1.0M
17.
Epstein-Barr Virus Independent Dysregulation of UBP43 Expression Alters Interferon-Stimulated Gene Expression in Burkitt Lymphoma
Ingrid K. Ruf, Jennifer L. Houmani, Jeffery T. Sample
PLoS One. 2009; 4(6): e6023. Published online 2009 Jun 24. doi: 10.1371/journal.pone.0006023
PMCID:
PMC2696598
AbstractArticlePDF–521K
18.
Type I IFNs Play a Role in Early Resistance, but Subsequent Susceptibility, to the African Trypanosomes
Rebecca Lopez, Karen P. Demick, John M. Mansfield, Donna M. Paulnock
J Immunol. Author manuscript; available in PMC 2009 Oct 1.
Published in final edited form as: J Immunol. 2008 Oct 1; 181(7): 4908–4917. doi: 10.4049/jimmunol.181.7.4908
PMCID:
PMC2582636
AbstractArticlePDF–1.8M
19.
Reexamination of the Role of Ubiquitin-Like Modifier ISG15 in the Phenotype of UBP43-Deficient Mice
Klaus-Peter Knobeloch, Olaf Utermöhlen, Agnes Kisser, Marco Prinz, Ivan Horak
Mol Cell Biol. 2005 Dec; 25(24): 11030–11034. doi: 10.1128/MCB.25.24.11030-11034.2005
PMCID:
PMC1316970
AbstractArticlePDF–327K
20.
Dysregulation of protein modification by ISG15 results in brain cell injury
Kenneth J. Ritchie, Michael P. Malakhov, Christopher J. Hetherington, Liming Zhou, Marie-Terese Little, Oxana A. Malakhova, Jack C. Sipe, Stuart H. Orkin, Dong-Er Zhang
Genes Dev. 2002 Sep 1; 16(17): 2207–2212. doi: 10.1101/gad.1010202
PMCID:
PMC186669
AbstractArticlePDF–229K

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