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Select item 89907341.

Compromised Cardiopulmonary Function in Fibulin-5 Deficient Mice

Abhay B. Ramachandra, Nicole Mikush, Maor Sauler, Jay D. Humphrey, Edward P. Manning

J Biomech Eng. 2022 Aug 1; 144(8): 081008. Published online 2022 Mar 11. doi: 10.1115/1.4053873

PMCID:: PMC8990734

Abstract Article PDF–4.7M

Select item 85460872.

Role of fibulin-5 insufficiency and prolapse progression on murine vaginal biomechanical function

Gabrielle L. Clark-Patterson, Sambit Roy, Laurephile Desrosiers, Leise R. Knoepp, Aritro Sen, Kristin S. Miller

Sci Rep. 2021; 11: 20956. Published online 2021 Oct 25. doi: 10.1038/s41598-021-00351-1

PMCID:: PMC8546087

Abstract Article PDF–2.4M

Select item 81460123.

Dysregulated assembly of elastic fibers in fibulin-5 knockout mice results in a tendon-specific increase in elastic modulus

Jeremy D. Eekhoff, Heiko Steenbock, Ian M. Berke, Jürgen Brinckmann, Hiromi Yanagisawa, Jessica E. Wagenseil, Spencer P. Lake

J Mech Behav Biomed Mater. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: J Mech Behav Biomed Mater. 2021 Jan; 113: 104134. Published online 2020 Oct 7. doi: 10.1016/j.jmbbm.2020.104134

PMCID:: PMC8146012

Abstract Article PDF–2.3M

Select item 75678414.

A nonlinear rotation-free shell formulation with prestressing for vascular biomechanics

Nitesh Nama, Miquel Aguirre, Jay D. Humphrey, C. Alberto Figueroa

Sci Rep. 2020; 10: 17528. Published online 2020 Oct 16. doi: 10.1038/s41598-020-74277-5

PMCID:: PMC7567841

Abstract Article PDF–2.4M

Select item 56579775.

Thermosensitive hydrogels deliver bioactive protein to the vaginal wall

Meadow M. Good, T. Ignacio Montoya, Haolin Shi, Jun Zhou, YiHui Huang, Liping Tang, Jesus F. Acevedo, R. Ann Word

PLoS One. 2017; 12(10): e0186268. Published online 2017 Oct 26. doi: 10.1371/journal.pone.0186268

PMCID:: PMC5657977

Abstract Article PDF–8.9M

Select item 46342196.

The matrix protein Fibulin-5 is at the interface of tissue stiffness and inflammation in fibrosis

Manando Nakasaki, Yongsung Hwang, Yun Xie, Sunny Kataria, Rupali Gund, Edries Y. Hajam, Rekha Samuel, Renu George, Debashish Danda, Paul M.J., Tomoyuki Nakamura, Zhouxin Shen, Steve Briggs, Shyni Varghese, Colin Jamora

Nat Commun. 2015; 6: 8574. Published online 2015 Oct 15. doi: 10.1038/ncomms9574

PMCID:: PMC4634219

Abstract Article PDF–1.4M

Select item 40022377.

Fibulin‐5 null mice with decreased arterial compliance maintain normal systolic left ventricular function, but not diastolic function during maturation

Victoria P. Le, Kellie V. Stoka, Hiromi Yanagisawa, Jessica E. Wagenseil

Physiol Rep. 2014 Mar; 2(3): e00257. Published online 2014 Mar 20. doi: 10.1002/phy2.257

PMCID:: PMC4002237

Abstract Article PDF–831K

Select item 37742078.

Effect of vaginal distention on elastic fiber synthesis and matrix degradation in the vaginal wall: potential role in the pathogenesis of pelvic organ prolapse

D. D. Rahn, J. F. Acevedo, R. A. Word

Am J Physiol Regul Integr Comp Physiol. 2008 Oct; 295(4): R1351–R1358. doi: 10.1152/ajpregu.90447.2008

PMCID:: PMC3774207

Abstract Article

Select item 36027589.

Dysfunction in elastic fiber formation in fibulin-5 null mice abrogates the evolution in mechanical response of carotid arteries during maturation

William Wan, Rudolph L. Gleason, Jr.

Am J Physiol Heart Circ Physiol. 2013 Mar 1; 304(5): H674–H686. Published online 2012 Dec 15. doi: 10.1152/ajpheart.00459.2012

PMCID:: PMC3602758

Abstract Article

Select item 309800610.

Biomechanical and Microstructural Properties of Common Carotid Arteries from Fibulin-5 Null Mice

William Wan, Hiromi Yanagisawa, Rudolph L. Gleason, Jr.

Ann Biomed Eng. Author manuscript; available in PMC 2011 May 19.

Published in final edited form as: Ann Biomed Eng. 2010 Dec; 38(12): 3605–3617. Published online 2010 Jul 8. doi: 10.1007/s10439-010-0114-3

PMCID:: PMC3098006

Abstract Article PDF–2.5M

Select item 269422211.

Analysis of Dermal Elastic Fibers in the Absence of Fibulin-5 Reveals Potential Roles for Fibulin-5 in Elastic Fiber Assembly

Jiwon Choi, Andreas Bergdahl, Qian Zheng, Barry Starcher, Hiromi Yanagisawa, Elaine C. Davis

Matrix Biol. Author manuscript; available in PMC 2010 May 1.

Published in final edited form as: Matrix Biol. 2009 May; 28(4): 211–220. Published online 2009 Mar 24. doi: 10.1016/j.matbio.2009.03.004

PMCID:: PMC2694222

Abstract Article PDF–1.9M

Select item 262110212.

Fibulin-5 initiates epithelial–mesenchymal transition (EMT) and enhances EMT induced by TGF-β in mammary epithelial cells via a MMP-dependent mechanism

Yong-Hun Lee, Allan R. Albig, MaryAnn Regner, Barbara J. Schiemann, William P. Schiemann

Carcinogenesis. 2008 Dec; 29(12): 2243–2251. Published online 2008 Aug 19. doi: 10.1093/carcin/bgn199

PMCID:: PMC2621102

Abstract Article PDF–1005K

Select item 185188213.

Pelvic Organ Prolapse in Fibulin-5 Knockout Mice : Pregnancy-Induced Changes in Elastic Fiber Homeostasis in Mouse Vagina

Peter G. Drewes, Hiromi Yanagisawa, Barry Starcher, Ian Hornstra, Katalin Csiszar, Spyridon I. Marinis, Patrick Keller, R. Ann Word

Am J Pathol. 2007 Feb; 170(2): 578–589. doi: 10.2353/ajpath.2007.060662

PMCID:: PMC1851882

Abstract Article PDF–775K

Select item 180069214.

Molecular Analysis of Fibulin-5 Function during De Novo Synthesis of Elastic Fibers

Qian Zheng, Elaine C. Davis, James A. Richardson, Barry C. Starcher, Tiansen Li, Robert D. Gerard, Hiromi Yanagisawa

Mol Cell Biol. 2007 Feb; 27(3): 1083–1095. Published online 2006 Nov 27. doi: 10.1128/MCB.01330-06

Correction in:: Mol Cell Biol. 2007 Mar; 27(5): 1990.

PMCID:: PMC1800692

Abstract Article PDF–2.1M

Select item 506400315.

Hypoxia and Transforming Growth Factor β Cooperate to Induce Fibulin-5 Expression in Pancreatic Cancer

Mary Topalovski, Michelle Hagopian, Miao Wang, Rolf A. Brekken

J Biol Chem. 2016 Oct 14; 291(42): 22244–22252. Published online 2016 Aug 16. doi: 10.1074/jbc.M116.730945

PMCID:: PMC5064003

Abstract Article PDF–2.3M

Select item 358191216.

Latent TGF-β binding protein 4 promotes elastic fiber assembly by interacting with fibulin-5

Kazuo Noda, Branka Dabovic, Kyoko Takagi, Tadashi Inoue, Masahito Horiguchi, Maretoshi Hirai, Yusuke Fujikawa, Tomoya O. Akama, Kenji Kusumoto, Lior Zilberberg, Lynn Y. Sakai, Katri Koli, Motoko Naitoh, Harald von Melchner, Shigehiko Suzuki, Daniel B. Rifkin, Tomoyuki Nakamura

Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8): 2852–2857. Published online 2013 Feb 4. doi: 10.1073/pnas.1215779110

PMCID:: PMC3581912

Abstract Article PDF–1.4M

Select item 357780717.

Dysregulation of Protease and Protease Inhibitors in a Mouse Model of Human Pelvic Organ Prolapse

Madhusudhan Budatha, Simone Silva, Teodoro Ignacio Montoya, Ayako Suzuki, Sheena Shah-Simpson, Cecilia Karin Wieslander, Masashi Yanagisawa, Ruth Ann Word, Hiromi Yanagisawa

PLoS One. 2013; 8(2): e56376. Published online 2013 Feb 20. doi: 10.1371/journal.pone.0056376

PMCID:: PMC3577807

Abstract Article PDF–1.1M

Select item 286085218.

Loss of fibulin-5 binding to β1 integrins inhibits tumor growth by increasing the level of ROS

Marie K. Schluterman, Shelby L. Chapman, Grzegorz Korpanty, Kiyoshi Ozumi, Tohru Fukai, Hiromi Yanagisawa, Rolf A. Brekken

Dis Model Mech. 2010 May-Jun; 3(5-6): 333–342. Published online 2010 Mar 2. doi: 10.1242/dmm.003707

PMCID:: PMC2860852

Abstract Article

Select item 280083119.

Fibulin-2 and fibulin-5 cooperatively function to form the internal elastic lamina and protect from vascular injury

Shelby L. Chapman, F-X Sicot, Elaine C. Davis, Jianbin Huang, Takako Sasaki, Mon-Li Chu, Hiromi Yanagisawa

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2011 Jan 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2010 Jan; 30(1): 68–74. Published online 2009 Nov 5. doi: 10.1161/ATVBAHA.109.196725

PMCID:: PMC2800831

Abstract Article PDF–1.7M

Select item 54945920.

Altered vascular remodeling in fibulin-5-deficient mice reveals a role of fibulin-5 in smooth muscle cell proliferation and migration

Jeffrey A. Spencer, Shelby L. Hacker, Elaine C. Davis, Robert P. Mecham, Russ H. Knutsen, Dean Y. Li, Robert D. Gerard, James A. Richardson, Eric N. Olson, Hiromi Yanagisawa

Proc Natl Acad Sci U S A. 2005 Feb 22; 102(8): 2946–2951. Published online 2005 Feb 14. doi: 10.1073/pnas.0500058102