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Select item 94766301.

Developmental disruption to the cortical transcriptome and synaptosome in a model of SETD1A loss-of-function

Nicholas E Clifton, Matthew L Bosworth, Niels Haan, Elliott Rees, Peter A Holmans, Lawrence S Wilkinson, Anthony R Isles, Mark O Collins, Jeremy Hall

Hum Mol Genet. 2022 Sep 15; 31(18): 3095–3106. Published online 2022 May 9. doi: 10.1093/hmg/ddac105

PMCID:: PMC9476630

Abstract Article PDF–1018K

Select item 91846432.

An in vitro model of neuronal ensembles

M. Angeles Rabadan, Estanislao Daniel De La Cruz, Sneha B. Rao, Yannan Chen, Cheng Gong, Gregg Crabtree, Bin Xu, Sander Markx, Joseph A. Gogos, Rafael Yuste, Raju Tomer

Nat Commun. 2022; 13: 3340. Published online 2022 Jun 9. doi: 10.1038/s41467-022-31073-1

PMCID:: PMC9184643

Abstract Article PDF–3.9M

Select item 91716093.

A synthetic lethality screen reveals ING5 as a genetic dependency of catalytically dead Set1A/COMPASS in mouse embryonic stem cells

Bercin K. Cenik, Christie C. Sze, Caila A. Ryan, Siddhartha Das, Kaixiang Cao, Delphine Douillet, Emily J. Rendleman, Didi Zha, Nabiha Haleema Khan, Elizabeth Bartom, Ali Shilatifard

Proc Natl Acad Sci U S A. 2022 May 10; 119(19): e2118385119. Published online 2022 May 2. doi: 10.1073/pnas.2118385119

PMCID:: PMC9171609

Abstract Article PDF–2.6M

Select item 56666724.

Histone H3K4 methylation-dependent and -independent functions of Set1A/COMPASS in embryonic stem cell self-renewal and differentiation

Christie C. Sze, Kaixiang Cao, Clayton K. Collings, Stacy A. Marshall, Emily J. Rendleman, Patrick A. Ozark, Fei Xavier Chen, Marc A. Morgan, Lu Wang, Ali Shilatifard

Genes Dev. 2017 Sep 1; 31(17): 1732–1737. doi: 10.1101/gad.303768.117

PMCID:: PMC5666672

Abstract Article PDF–4.7M

Select item 54358915.

SET1A/COMPASS and shadow enhancers in the regulation of homeotic gene expression

Kaixiang Cao, Clayton K. Collings, Stacy A. Marshall, Marc A. Morgan, Emily J. Rendleman, Lu Wang, Christie C. Sze, Tianjiao Sun, Elizabeth T. Bartom, Ali Shilatifard

Genes Dev. 2017 Apr 15; 31(8): 787–801. doi: 10.1101/gad.294744.116

PMCID:: PMC5435891

Abstract Article PDF–603K

Select item 43966056.

Setd1a regulates progenitor B-cell-to-precursor B-cell development through histone H3 lysine 4 trimethylation and Ig heavy-chain rearrangement

Betsabeh Khoramian Tusi, Changwang Deng, Tal Salz, Leilani Zeumer, Yangqiu Li, Chi Wai Eric So, Laurence M. Morel, Yi Qiu, Suming Huang

FASEB J. 2015 Apr; 29(4): 1505–1515. Published online 2014 Dec 30. doi: 10.1096/fj.14-263061

PMCID:: PMC4396605

Abstract Article

Select item 102561737.

Distorted neurocomputation by a small number of extra-large spines in psychiatric disorders

Kisho Obi-Nagata, Norimitsu Suzuki, Ryuhei Miyake, Matthew L. MacDonald, Kenneth N. Fish, Katsuya Ozawa, Kenichiro Nagahama, Tsukasa Okimura, Shoji Tanaka, Masanobu Kano, Yugo Fukazawa, Robert A. Sweet, Akiko Hayashi-Takagi

Sci Adv. 2023 Jun; 9(23): eade5973. Published online 2023 Jun 9. doi: 10.1126/sciadv.ade5973

PMCID:: PMC10256173

Abstract Article PDF–1.8M

Select item 81074988.

Setd1a Plays Pivotal Roles for the Survival and Proliferation of Retinal Progenitors via Histone Modifications of Uhrf1

Xiaoyue Deng, Toshiro Iwagawa, Masaya Fukushima, Yutaka Suzuki, Sumiko Watanabe

Invest Ophthalmol Vis Sci. 2021 May; 62(6): 1. Published online 2021 May 3. doi: 10.1167/iovs.62.6.1

PMCID:: PMC8107498

Abstract Article PDF–10M

Select item 68641549.

De Novo and Inherited SETD1A Variants in Early-onset Epilepsy

Xiuya Yu, Lin Yang, Jin Li, Wanxing Li, Dongzhi Li, Ran Wang, Kai Wu, Wenhao Chen, Yi Zhang, Zilong Qiu, Wenhao Zhou

Neurosci Bull. 2019 Dec; 35(6): 1045–1057. Published online 2019 Jun 13. doi: 10.1007/s12264-019-00400-w

PMCID:: PMC6864154

Abstract Article PDF–2.2M

Select item 1122758910.

Epigenetic maintenance of adult neural stem cell quiescence in the mouse hippocampus via Setd1a

Ting Zhao, Yan Hong, Bowen Yan, Suming Huang, Guo-li Ming, Hongjun Song

Nat Commun. 2024; 15: 5674. Published online 2024 Jul 6. doi: 10.1038/s41467-024-50010-y

PMCID:: PMC11227589

Abstract Article PDF–3.7M

Select item 889679311.

Cell type–specific mechanism of Setd1a heterozygosity in schizophrenia pathogenesis

Renchao Chen, Yiqiong Liu, Mohamed N. Djekidel, Wenqiang Chen, Aritra Bhattacherjee, Zhiyuan Chen, Ed Scolnick, Yi Zhang

Sci Adv. 2022 Mar; 8(9): eabm1077. Published online 2022 Mar 4. doi: 10.1126/sciadv.abm1077

PMCID:: PMC8896793

Abstract Article PDF–2.2M

Select item 603006412.

Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a

Kun-Yong Kim, Yoshiaki Tanaka, Juan Su, Bilal Cakir, Yangfei Xiang, Benjamin Patterson, Junjun Ding, Yong-Wook Jung, Ji-Hyun Kim, Eriona Hysolli, Haelim Lee, Rana Dajani, Jonghwan Kim, Mei Zhong, Jeong-Heon Lee, David Skalnik, Jeong Mook Lim, Gareth J. Sullivan, Jianlong Wang, In-Hyun Park

Nat Commun. 2018; 9: 2583. Published online 2018 Jul 3. doi: 10.1038/s41467-018-04818-0

PMCID:: PMC6030064

Abstract Article PDF–3.3M

Select item 383284613.

Age–dependent regulation of synaptic connections by dopamine D2 receptors

Jie–Min Jia, Jun Zhao, Zhonghua Hu, Daniel Lindberg, Zheng Li

Nat Neurosci. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Nat Neurosci. 2013 Nov; 16(11): 1627–1636. Published online 2013 Oct 13. doi: 10.1038/nn.3542

PMCID:: PMC3832846

Abstract Article PDF–3.2M

Select item 787383714.

The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers

Franziska Greulich, Michael Wierer, Aikaterini Mechtidou, Omar Gonzalez-Garcia, N. Henriette Uhlenhaut

Cell Rep. 2021 Feb 9; 34(6): 108742. Published online 2021 Feb 9. doi: 10.1016/j.celrep.2021.108742

PMCID:: PMC7873837

Abstract Article

Select item 529782315.

MicroRNA-29a Alleviates Bile Duct Ligation Exacerbation of Hepatic Fibrosis in Mice through Epigenetic Control of Methyltransferases

Ya-Ling Yang, Feng-Sheng Wang, Sung-Chou Li, Mao-Meng Tiao, Ying-Hsien Huang

Int J Mol Sci. 2017 Jan; 18(1): 192. Published online 2017 Jan 18. doi: 10.3390/ijms18010192

PMCID:: PMC5297823

Abstract Article PDF–7.4M

Select item 280659816.

CXXC Finger Protein 1 Restricts the Setd1A Histone H3-Lys4 Methyltransferase Complex to Euchromatin

Courtney M. Tate, Jeong-Heon Lee, David G. Skalnik

FEBS J. Author manuscript; available in PMC 2011 Jan 1.

Published in final edited form as: FEBS J. 2010 Jan; 277(1): 210–223. Published online 2009 Nov 27. doi: 10.1111/j.1742-4658.2009.07475.x

Correction in:: volume 277 on page 2564

PMCID:: PMC2806598

Abstract Article PDF–1.9M

Select item 701034817.

Recapitulation and reversal of schizophrenia-related phenotypes in Setd1a-deficient mice

Jun Mukai, Enrico Cannavò, Gregg W. Crabtree, Ziyi Sun, Anastasia Diamantopoulou, Pratibha Thakur, Chia-Yuan Chang, Yifei Cai, Stavros Lomvardas, Atsushi Takata, Bin Xu, Joseph A. Gogos

Neuron. Author manuscript; available in PMC 2020 Nov 6.

Published in final edited form as: Neuron. 2019 Nov 6; 104(3): 471–487.e12. Published online 2019 Oct 9. doi: 10.1016/j.neuron.2019.09.014

PMCID:: PMC7010348

Abstract Article PDF–2.0M

Select item 500972418.

Setd1a and NURF mediate chromatin dynamics and gene regulation during erythroid lineage commitment and differentiation

Ying Li, Vincent P. Schulz, Changwang Deng, Guangyao Li, Yong Shen, Betsabeh K. Tusi, Gina Ma, Jared Stees, Yi Qiu, Laurie A. Steiner, Lei Zhou, Keji Zhao, Jörg Bungert, Patrick G. Gallagher, Suming Huang

Nucleic Acids Res. 2016 Sep 6; 44(15): 7173–7188. Published online 2016 May 3. doi: 10.1093/nar/gkw327

PMCID:: PMC5009724

Abstract Article PDF–6.6M

Select item 386937519.

H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation

Ji-Eun Lee, Chaochen Wang, Shiliyang Xu, Young-Wook Cho, Lifeng Wang, Xuesong Feng, Anne Baldridge, Vittorio Sartorelli, Lenan Zhuang, Weiqun Peng, Kai Ge

eLife. 2013; 2: e01503. Published online 2013 Dec 24. doi: 10.7554/eLife.01503

PMCID:: PMC3869375

Abstract Article PDF–5.8M

Select item 605244520.

A non-catalytic function of SETD1A regulates Cyclin-K and the DNA damage response

Takayuki Hoshii, Paolo Cifani, Zhaohui Feng, Chun-Hao Huang, Richard Koche, Chun-Wei Chen, Christopher D. Delaney, Scott W. Lowe, Alex Kentsis, Scott A. Armstrong

Cell. Author manuscript; available in PMC 2019 Feb 22.

Published in final edited form as: Cell. 2018 Feb 22; 172(5): 1007–1021.e17. doi: 10.1016/j.cell.2018.01.032