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Select item 99507361.

Early-life hyperoxia-induced Flt3L drives neonatal lung dendritic cell expansion and proinflammatory responses

Tracy X. Cui, Alexander E. Brady, Ying-Jian Zhang, Christina T. Fulton, Adam M. Goldsmith, Antonia P. Popova

Front Immunol. 2023; 14: 1116675. Published online 2023 Feb 10. doi: 10.3389/fimmu.2023.1116675

PMCID:: PMC9950736

Abstract Article PDF–4.9M

Select item 65558002.

Mesenchymal stem cell therapy induces FLT3L and CD1c⁺ dendritic cells in systemic lupus erythematosus patients

Xinran Yuan, Xiaodong Qin, Dandan Wang, Zhuoya Zhang, Xiaojun Tang, Xiang Gao, Wanjun Chen, Lingyun Sun

Nat Commun. 2019; 10: 2498. Published online 2019 Jun 7. doi: 10.1038/s41467-019-10491-8

PMCID:: PMC6555800

Abstract Article PDF–1.6M

Select item 65458313.

FLT3 ligand plasma levels in acute myeloid leukemia

Pierre Peterlin, Joelle Gaschet, Thierry Guillaume, Alice Garnier, Marion Eveillard, Amandine Le Bourgeois, Michel Cherel, Camille Debord, Yannick Le Bris, Olivier Theisen, Béatrice Mahé, Viviane Dubruille, Catherine Godon, Nelly Robillard, Soraya Wuilleme, Cyrille Touzeau, Thomas Gastinne, Nicolas Blin, Anne Lok, Antoine Bonnet, Steven Le Gouill, Philippe Moreau, Marie-C Béné, Patrice Chevallier

Haematologica. 2019 Jun; 104(6): e240–e243. doi: 10.3324/haematol.2018.209460

PMCID:: PMC6545831

Article PDF–288K

Select item 59599274.

Systemic immune response induced by oxaliplatin-based neoadjuvant therapy favours survival without metastatic progression in high-risk rectal cancer

Erta Kalanxhi, Sebastian Meltzer, Jakob Vasehus Schou, Finn Ole Larsen, Svein Dueland, Kjersti Flatmark, Benny Vittrup Jensen, Knut Håkon Hole, Therese Seierstad, Kathrine Røe Redalen, Dorte Lisbet Nielsen, Anne Hansen Ree

Br J Cancer. 2018 May 15; 118(10): 1322–1328. Published online 2018 Apr 26. doi: 10.1038/s41416-018-0085-y

PMCID:: PMC5959927

Abstract Article PDF–387K

Select item 52169205.

Co-expression of wild-type FLT3 attenuates the inhibitory effect of FLT3 inhibitor on FLT3 mutated leukemia cells

Fangli Chen, Yuichi Ishikawa, Akimi Akashi, Tomoki Naoe, Hitoshi Kiyoi

Oncotarget. 2016 Jul 26; 7(30): 47018–47032. Published online 2016 Jun 17. doi: 10.18632/oncotarget.10147

PMCID:: PMC5216920

Abstract Article PDF–4.4M

Select item 30696706.

FLT3 ligand impedes the efficacy of FLT3 inhibitors in vitro and in vivo

Takashi Sato, Xiaochuan Yang, Steven Knapper, Paul White, B. Douglas Smith, Steven Galkin, Donald Small, Alan Burnett, Mark Levis

Blood. 2011 Mar 24; 117(12): 3286–3293. Prepublished online 2011 Jan 24. doi: 10.1182/blood-2010-01-266742

PMCID:: PMC3069670

Abstract Article

Select item 28840157.

Human Flt3L Generates Dendritic Cells from Canine Peripheral Blood Precursors: Implications for a Dog Glioma Clinical Trial

Weidong Xiong, Marianela Candolfi, Chunyan Liu, A. K. M. Ghulam Muhammad, Kader Yagiz, Mariana Puntel, Peter F. Moore, Julie Avalos, John D. Young, Dorothy Khan, Randy Donelson, G. Elizabeth Pluhar, John R. Ohlfest, Kolja Wawrowsky, Pedro R. Lowenstein, Maria G. Castro

PLoS One. 2010; 5(6): e11074. Published online 2010 Jun 11. doi: 10.1371/journal.pone.0011074

PMCID:: PMC2884015

Abstract Article PDF–3.8M

Select item 25758558.

Intra-Articular Fms-Like Tyrosine Kinase 3 Ligand Expression Is a Driving Force in Induction and Progression of Arthritis

Mats Dehlin, Maria Bokarewa, Robert Rottapel, Simon J. Foster, Mattias Magnusson, Leif E. Dahlberg, Andrej Tarkowski

PLoS One. 2008; 3(11): e3633. Published online 2008 Nov 4. doi: 10.1371/journal.pone.0003633

PMCID:: PMC2575855

Abstract Article PDF–235K

Select item 94452539.

FLT3LG and IFITM3P6 consolidate T cell activity in the bone marrow microenvironment and are prognostic factors in acute myelocytic leukemia

Haiyan Chen, Meng Wu, Hongping Xia, Songjie Du, Guoren Zhou, Guangfeng Long, Yanan Zhu, Xu Huang, Daheng Yang

Front Immunol. 2022; 13: 980911. Published online 2022 Aug 23. doi: 10.3389/fimmu.2022.980911

PMCID:: PMC9445253

Abstract Article PDF–17M

Select item 890714910.

Fast Maturation of Splenic Dendritic Cells Upon TBI Is Associated With FLT3/FLT3L Signaling

Jin Zhang, Zhenghui Li, Akila Chandrasekar, Shun Li, Albert Ludolph, Tobias Maria Boeckers, Markus Huber-Lang, Francesco Roselli, Florian olde Heuvel

Front Immunol. 2022; 13: 824459. Published online 2022 Feb 24. doi: 10.3389/fimmu.2022.824459

PMCID:: PMC8907149

Abstract Article PDF–33M

Select item 787735811.

A new cytokine‐based dynamic stratification during induction is highly predictive of survivals in acute myeloid leukemia

Pierre Peterlin, Joelle Gaschet, Thierry Guillaume, Alice Garnier, Marion Eveillard, Amandine Le Bourgeois, Michel Cherel, Camille Debord, Yannick Le Bris, Olivier Theisen, Catherine Godon, Béatrice Mahé, Viviane Dubruille, Soraya Wuilleme, Cyrille Touzeau, Thomas Gastinne, Nicolas Blin, Anne Lok, Benoît Tessoulin, Steven Le Gouill, Philippe Moreau, Marie‐C Béné, Patrice Chevallier

Cancer Med. 2021 Jan; 10(2): 642–648. Published online 2020 Dec 25. doi: 10.1002/cam4.3648

PMCID:: PMC7877358

Abstract Article PDF–282K

Select item 598530412.

Introduction of Human Flt3-L and GM-CSF into Humanized Mice Enhances the Reconstitution and Maturation of Myeloid Dendritic Cells and the Development of Foxp3⁺CD4⁺ T Cells

Ryutaro Iwabuchi, Shota Ikeno, Mie Kobayashi-Ishihara, Haruko Takeyama, Manabu Ato, Yasuko Tsunetsugu-Yokota, Kazutaka Terahara

Front Immunol. 2018; 9: 1042. Published online 2018 May 28. doi: 10.3389/fimmu.2018.01042

PMCID:: PMC5985304

Abstract Article PDF–3.2M

Select item 548593913.

The Cytokine Flt3-Ligand in Normal and Malignant Hematopoiesis

Panagiotis Tsapogas, Ciaran James Mooney, Geoffrey Brown, Antonius Rolink

Int J Mol Sci. 2017 Jun; 18(6): 1115. Published online 2017 May 24. doi: 10.3390/ijms18061115

PMCID:: PMC5485939

Abstract Article PDF–1.6M

Select item 397861114.

Maria I Ramos, Samuel Garcia Perez, Saida Aarrass, Boy Helder, Pleun Broekstra, Daan M Gerlag, Kris A Reedquist, Paul Peter Tak, Maria C Lebre

Arthritis Res Ther. 2013; 15(6): R209. Published online 2013 Dec 6. doi: 10.1186/ar4403

PMCID:: PMC3978611

Abstract Article PDF–2.0M

Select item 318875615.

Combined Flt3L/TK Gene Therapy Induces Immunological Surveillance Which Mediates an Immune Response Against a Surrogate Brain Tumor Neoantigen

Gwendalyn D King, AKM Ghulam Muhammad, Daniel Larocque, Kyle R Kelson, Weidong Xiong, Chunyan Liu, Nicholas SR Sanderson, Kurt M Kroeger, Maria G Castro, Pedro R Lowenstein

Mol Ther. 2011 Oct; 19(10): 1793–1801. Published online 2011 Apr 19. doi: 10.1038/mt.2011.77

PMCID:: PMC3188756

Abstract Article PDF–616K

Select item 151095416.

Thrombopoietin cooperates with FLT3-ligand in the generation of plasmacytoid dendritic cell precursors from human hematopoietic progenitors

Wei Chen, Svetlana Antonenko, Joel M. Sederstrom, Xueqing Liang, Anissa S. H. Chan, Holger Kanzler, Bianca Blom, Bruce R. Blazar, Yong-Jun Liu

Blood. Author manuscript; available in PMC 2006 Jul 18.

Published in final edited form as: Blood. 2004 Apr 1; 103(7): 2547–2553. Published online 2003 Dec 11. doi: 10.1182/blood-2003-09-3058

PMCID:: PMC1510954

Abstract Article PDF–556K

Select item 1114963017.

FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice

Mana Momenilandi, Romain Lévy, Steicy Sobrino, Jingwei Li, Chantal Lagresle-Peyrou, Hossein Esmaeilzadeh, Antoine Fayand, Corentin Le Floc’h, Antoine Guérin, Erika Della Mina, Debra Shearer, Ottavia M. Delmonte, Ahmad Yatim, Kevin Mulder, Mathieu Mancini, Darawan Rinchai, Adeline Denis, Anna-Lena Neehus, Karla Balogh, Sarah Brendle, Hassan Rokni-Zadeh, Majid Changi-Ashtiani, Yoann Seeleuthner, Caroline Deswarte, Boris Bessot, Cassandre Cremades, Marie Materna, Axel Cederholm, Masato Ogishi, Quentin Philippot, Omer Beganovic, Mania Ackermann, Margareta Wuyts, Taushif Khan, Sébastien Fouéré, Florian Herms, Johan Chanal, Boaz Palterer, Julie Bruneau, Thierry Molina, Stéphanie Leclerc-Mercier, Jean-Luc Prétet, Leila Youssefian, Hassan Vahidnezhad, Nima Parvaneh, Kristl G. Claeys, Rik Schrijvers, Marine Luka, Philippe Pérot, Jacques Fourgeaud, Céline Nourrisson, Philippe Poirier, Emmanuelle Jouanguy, Stéphanie Boisson-Dupuis, Jacinta Bustamante, Luigi D. Notarangelo, Neil Christensen, Nils Landegren, Laurent Abel, Nico Marr, Emmanuelle Six, David Langlais, Tim Waterboer, Florent Ginhoux, Cindy S. Ma, Stuart G Tangye, Isabelle Meyts, Nico Lachmann, Jiafen Hu, Mohammad Shahrooei, Xavier Bossuyt, Jean-Laurent Casanova, Vivien Béziat

Cell. Author manuscript; available in PMC 2024 Jun 4.

Published in final edited form as: Cell. 2024 May 23; 187(11): 2817–2837.e31. Published online 2024 May 3. doi: 10.1016/j.cell.2024.04.009

PMCID:: PMC11149630

Abstract Article PDF–3.3M

Select item 717685318.

Wild‐type FLT3 and FLT3 ITD exhibit similar ligand‐induced internalization characteristics

Fabienne Kellner, Andreas Keil, Katrin Schindler, Todor Tschongov, Kerstin Hünninger, Hannah Loercher, Peter Rhein, Sylvia‐Annette Böhmer, Frank‐D. Böhmer, Jörg P. Müller

J Cell Mol Med. 2020 Apr; 24(8): 4668–4676. Published online 2020 Mar 10. doi: 10.1111/jcmm.15132

PMCID:: PMC7176853

Abstract Article PDF–721K

Select item 576064219.

Flt3 ligand expands bona fide innate lymphoid cell precursors in vivo

Sara M. Parigi, Paulo Czarnewski, Srustidhar Das, Christiane Steeg, Leonie Brockmann, Sara Fernandez-Gaitero, Victor Yman, Marianne Forkel, Charlotte Höög, Jenny Mjösberg, Lisa Westerberg, Anna Färnert, Samuel Huber, Thomas Jacobs, Eduardo J. Villablanca

Sci Rep. 2018; 8: 154. Published online 2018 Jan 9. doi: 10.1038/s41598-017-18283-0

PMCID:: PMC5760642

Abstract Article PDF–4.6M

Select item 292475020.

In Vivo Role of Flt3 Ligand and Dendritic Cells in NK Cell Homeostasis

Martin Guimond, Aharon G. Freud, Hsiaoyin C. Mao, Jianhua Yu, Bradley W. Blaser, Jeffrey W. Leong, Jeffrey B. Vandeusen, Adrienne Dorrance, Jianying Zhang, Crystal L. Mackall, Michael A. Caligiuri

J Immunol. Author manuscript; available in PMC 2010 Aug 20.

Published in final edited form as: J Immunol. 2010 Mar 15; 184(6): 2769–2775. Published online 2010 Feb 8. doi: 10.4049/jimmunol.0900685

PMCID:: PMC2924750

Abstract Article PDF–666K

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