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Items: 1 to 20 of 40

1.
Noncanonical assembly, neddylation and chimeric cullin–RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex
Daniel Horn-Ghetko, Linus V. M. Hopf, Ishita Tripathi-Giesgen, Jiale Du, Sebastian Kostrhon, D. Tung Vu, Viola Beier, Barbara Steigenberger, J. Rajan Prabu, Luca Stier, Elias M. Bruss, Matthias Mann, Yue Xiong, Brenda A. Schulman
Nat Struct Mol Biol. 2024; 31(7): 1083–1094. Published online 2024 Apr 11. doi: 10.1038/s41594-024-01257-y
PMCID:
PMC11257990
AbstractArticlePDF–18M
2.
Activation of p53-dependent responses in tumour cells treated with a PARC-interacting peptide
Roberta Vitali, Vincenzo Cesi, Barbara Tanno, Giovanna Ferrari-Amorotti, Carlo Dominici, Bruno Calabretta, Giuseppe Raschellà
Biochem Biophys Res Commun. Author manuscript; available in PMC 2020 Aug 3.
Published in final edited form as: Biochem Biophys Res Commun. 2008 Apr 4; 368(2): 350–356. Published online 2008 Jan 28. doi: 10.1016/j.bbrc.2008.01.093
PMCID:
PMC7398582
AbstractArticlePDF–1.0M
3.
Calpain-mediated Processing of p53-associated Parkin-like Cytoplasmic Protein (PARC) Affects Chemosensitivity of Human Ovarian Cancer Cells by Promoting p53 Subcellular Trafficking
Michael G. Woo, Kai Xue, Jiayin Liu, Heidi McBride, Benjamin K. Tsang
J Biol Chem. 2012 Feb 3; 287(6): 3963–3975. Published online 2011 Nov 23. doi: 10.1074/jbc.M111.314765
PMCID:
PMC3281727
AbstractArticlePDF–3.2M
4.
Expression of a mutant p193/CUL7 molecule confers resistance to MG132- and etoposide-induced apoptosis independent of p53 or Parc binding.
Joshua D. Dowell, Shih-Chong Tsai, Dora C. Dias-Santagata, Hidehiro Nakajima, Zhuo Wang, Wuqiang Zhu, Loren J. Field
Biochim Biophys Acta. Author manuscript; available in PMC 2008 Mar 1.
Published in final edited form as: Biochim Biophys Acta. 2007 Mar; 1773(3): 358–366. Published online 2006 Dec 15. doi: 10.1016/j.bbamcr.2006.11.020
PMCID:
PMC1876763
AbstractArticlePDF–729K
5.
Cytoplasmic E3 ubiquitin ligase CUL9 controls cell proliferation, senescence, apoptosis and genome integrity through p53
Zhijun Li, Yue Xiong
Oncogene. Author manuscript; available in PMC 2017 Nov 8.
Published in final edited form as: Oncogene. 2017 Sep 7; 36(36): 5212–5218. Published online 2017 May 8. doi: 10.1038/onc.2017.141
PMCID:
PMC5589481
AbstractArticlePDF–654K
6.
Cytoplasmic CUL9/PARC ubiquitin ligase is a tumor suppressor and promotes p53-dependent apoptosis
Xin-Hai Pei, Feng Bai, Zhijun Li, Matthew D. Smith, Gabrielle Whitewolf, Ran Jin, Yue Xiong
Cancer Res. Author manuscript; available in PMC 2012 Apr 15.
Published in final edited form as: Cancer Res. 2011 Apr 15; 71(8): 2969–2977. Published online 2011 Apr 12. doi: 10.1158/0008-5472.CAN-10-4300
PMCID:
PMC3088989
AbstractArticlePDF–1.2M
7.
Dimerization of CUL7 and PARC Is Not Required for All CUL7 Functions and Mouse Development
Jeffrey R. Skaar, Takehiro Arai, James A. DeCaprio
Mol Cell Biol. 2005 Jul; 25(13): 5579–5589. doi: 10.1128/MCB.25.13.5579-5589.2005
PMCID:
PMC1156978
AbstractArticlePDF–536K
8.
PARC/CUL9 Mediates the Degradation of Mitochondrial-released Cytochrome c and Promotes Survival in Neurons and Cancer Cells
Vivian Gama, Vijay Swahari, Johanna Schafer, Adam J. Kole, Allyson Evans, Yolanda Huang, Anna Cliffe, Brian Golitz, Noah Sciaky, Xin-Hai Pei, Yue Xiong, Mohanish Deshmukh
Sci Signal. Author manuscript; available in PMC 2015 Jan 15.
Published in final edited form as: Sci Signal. 2014 Jul 15; 7(334): ra67. Published online 2014 Jul 15. doi: 10.1126/scisignal.2005309
PMCID:
PMC4182917
AbstractArticlePDF–1.8M
9.
CUL9 mediates the functions of the 3M complex and ubiquitylates survivin to maintain genome integrity
Zhijun Li, Xin-Hai Pei, Jun Yan, Feng Yan, Kathryn M. Cappell, Angelique W. Whitehurst, Yue Xiong
Mol Cell. Author manuscript; available in PMC 2015 Jun 5.
Published in final edited form as: Mol Cell. 2014 Jun 5; 54(5): 805–819. Published online 2014 May 1. doi: 10.1016/j.molcel.2014.03.046
PMCID:
PMC4172312
AbstractArticlePDF–3.7M
10.
Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53
Yajie Chen, Qian Hao, Jieqiong Wang, Jiajia Li, Canhua Huang, Yu Zhang, Xiaohua Wu, Hua Lu, Xiang Zhou
Cell Death Dis. 2019 Oct; 10(10): 737. Published online 2019 Sep 30. doi: 10.1038/s41419-019-1977-3
PMCID:
PMC6769007
AbstractArticlePDF–2.5M
11.
Mutant p53 interactome identifies nardilysin as a p53R273H-specific binding partner that promotes invasion
Cynthia R Coffill, Patricia A J Muller, Hue Kian Oh, Suat Peng Neo, Kelly A Hogue, Chit Fang Cheok, Karen H Vousden, David P Lane, Walter P Blackstock, Jayantha Gunaratne
EMBO Rep. 2012 Jul; 13(7): 638–644. Published online 2012 Jun 1. doi: 10.1038/embor.2012.74
PMCID:
PMC3388785
AbstractArticlePDF–687K
12.
A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models
Natalya A. Ortolano, Alejandra I. Romero-Morales, Megan L. Rasmussen, Caroline Bodnya, Leigh A. Kline, Piyush Joshi, Jon P. Connelly, Kristie L. Rose, Shondra M. Pruett-Miller, Vivian Gama
PLoS One. 2021; 16(3): e0248000. Published online 2021 Mar 11. doi: 10.1371/journal.pone.0248000
PMCID:
PMC7951927
AbstractArticlePDF–3.8M
13.
Tumor-associated antigen Prame targets tumor suppressor p14/ARF for degradation as the  receptor protein of CRL2Prame complex
Wenjuan Zhang, Lihui Li, Lili Cai, Yupei Liang, Junfeng Xu, Yue Liu, Lisha Zhou, Chen Ding, Yanmei Zhang, Hu Zhao, Jun Qin, Zhimin Shao, Wenyi Wei, Lijun Jia
Cell Death Differ. 2021 Jun; 28(6): 1926–1940. Published online 2021 Jan 27. doi: 10.1038/s41418-020-00724-5
PMCID:
PMC8184998
AbstractArticlePDF–4.0M
14.
A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity
Danielle L. Swaney, Dana J. Ramms, Zhiyong Wang, Jisoo Park, Yusuke Goto, Margaret Soucheray, Neil Bhola, Kyumin Kim, Fan Zheng, Yan Zeng, Michael McGregor, Kari A. Herrington, Rachel O’Keefe, Nan Jin, Nathan K. VanLandingham, Helene Foussard, John Von Dollen, Mehdi Bouhaddou, David Jimenez-Morales, Kirsten Obernier, Jason F. Kreisberg, Minkyu Kim, Daniel E. Johnson, Natalia Jura, Jennifer R. Grandis, J. Silvio Gutkind, Trey Ideker, Nevan J. Krogan
Science. Author manuscript; available in PMC 2022 Apr 13.
Published in final edited form as: Science. 2021 Oct; 374(6563): eabf2911. Published online 2021 Oct 1. doi: 10.1126/science.abf2911
PMCID:
PMC9005332
AbstractArticlePDF–2.0M
15.
Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer‐related pathways in breast cancer
Yan Liu, Jian Li, Zhifang Ma, Jun Zhang, Yuzhi Wang, Zhenghong Yu, Xue Lin, Zhi Xu, Qian Su, Li An, Yehui Zhou, Xinxing Ma, Yiwen Yang, Feifei Wang, Qingfei Chen, Yunchao Zhang, Jilinlin Wang, Huilin Zheng, Aihua Shi, Shuang Yu, Jingzhong Zhang, Weiyong Zhao, Liming Chen
Cancer Med. 2019 Feb; 8(2): 729–741. Published online 2019 Jan 16. doi: 10.1002/cam4.1938
PMCID:
PMC6504119
AbstractArticlePDF–1.3M
16.
Protein–Protein Interactions Between Large Proteins: Two-Hybrid Screening Using a Functionally Classified Library Composed of Long cDNAs
Manabu Nakayama, Reiko Kikuno, Osamu Ohara
Genome Res. 2002 Nov; 12(11): 1773–1784. doi: 10.1101/gr.406902
PMCID:
PMC187542
AbstractArticlePDF–374K
17.
Cytoplasmic Metadherin (MTDH) Provides Survival Advantage under Conditions of Stress by Acting as RNA-binding Protein
Xiangbing Meng, Danlin Zhu, Shujie Yang, Xinjun Wang, Zhi Xiong, Yuping Zhang, Pavla Brachova, Kimberly K. Leslie
J Biol Chem. 2012 Feb 10; 287(7): 4485–4491. Published online 2011 Dec 23. doi: 10.1074/jbc.C111.291518
PMCID:
PMC3281628
AbstractArticlePDF–2.0M
18.
The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1
Lee D. Harris, Janic Le Pen, Nico Scholz, Juliusz Mieszczanek, Natalie Vaughan, Simon Davis, Georgina Berridge, Benedikt M. Kessler, Mariann Bienz, Julien D.F. Licchesi
J Biol Chem. 2021 Jan-Jun; 296: 100246. Published online 2021 Jan 8. doi: 10.1074/jbc.RA120.015162
PMCID:
PMC7948964
AbstractArticlePDF–2.7M
19.
Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies
Christina Schiza, Dimitrios Korbakis, Efstratia Panteleli, Keith Jarvi, Andrei P. Drabovich, Eleftherios P. Diamandis
Mol Cell Proteomics. 2018 Dec; 17(12): 2480–2495. Published online 2018 Aug 10. doi: 10.1074/mcp.RA118.000749
PMCID:
PMC6283293
AbstractArticlePDF–1.9M
20.
The SOX2-Interactome in Brain Cancer Cells Identifies the Requirement of MSI2 and USP9X for the Growth of Brain Tumor Cells
Jesse L. Cox, Phillip J. Wilder, Joshua M. Gilmore, Erin L. Wuebben, Michael P. Washburn, Angie Rizzino
PLoS One. 2013; 8(5): e62857. Published online 2013 May 7. doi: 10.1371/journal.pone.0062857
PMCID:
PMC3647065
AbstractArticlePDF–5.0M

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