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Items: 1 to 20 of 47

1.
Ikzf2 Regulates the Development of ICOS+ Th Cells to Mediate Immune Response in the Spleen of S. japonicum-Infected C57BL/6 Mice
Shihao Xie, Haixia Wei, Anping Peng, Anqi Xie, Jiajie Li, Chao Fang, Feihu Shi, Quan Yang, He Huang, Hongyan Xie, Xingfei Pan, Xu Tian, Jun Huang
Front Immunol. 2021; 12: 687919. Published online 2021 Aug 12. doi: 10.3389/fimmu.2021.687919
PMCID:
PMC8406689
AbstractArticlePDF–3.7M
2.
Lack of Helios During Neural Development Induces Adult Schizophrenia-Like Behaviors Associated With Aberrant Levels of the TRIF-Recruiter Protein WDFY1
Anna Sancho-Balsells, Veronica Brito, Belissa Fernández, Mónica Pardo, Marco Straccia, Silvia Ginés, Jordi Alberch, Isabel Hernández, Belén Arranz, Josep M. Canals, Albert Giralt
Front Cell Neurosci. 2020; 14: 93. Published online 2020 May 14. doi: 10.3389/fncel.2020.00093
PMCID:
PMC7240114
AbstractArticlePDF–3.8M
3.
IKZF2 drives leukemia stem cell self-renewal and inhibits myeloid differentiation
Sun-Mi Park, Hyunwoo Cho, Angela M. Thornton, Trevor S. Barlowe, Timothy Chou, Sagar Chhangawala, Lauren Fairchild, James Taggart, Arthur Chow, Alexandria Schurer, Antoine Gruet, Matthew D. Witkin, Jun Hyun Kim, Ethan M. Shevach, Andrei Krivtsov, Scott A. Armstrong, Christina Leslie, Michael G. Kharas
Cell Stem Cell. Author manuscript; available in PMC 2020 Jan 3.
Published in final edited form as: Cell Stem Cell. 2019 Jan 3; 24(1): 153–165.e7. Published online 2018 Nov 21. doi: 10.1016/j.stem.2018.10.016
PMCID:
PMC6602096
AbstractArticlePDF–2.6M
4.
Helios+ and Helios− Treg subpopulations are phenotypically and functionally distinct and express dissimilar TCR repertoires
Angela M. Thornton, Jinghua Lu, Patricia E. Korty, Yong Chan Kim, Craig Martens, Peter D. Sun, Ethan M. Shevach
Eur J Immunol. Author manuscript; available in PMC 2020 Mar 1.
Published in final edited form as: Eur J Immunol. 2019 Mar; 49(3): 398–412. Published online 2019 Jan 15. doi: 10.1002/eji.201847935
PMCID:
PMC6402968
AbstractArticlePDF–2.5M
5.
Phenotypic and Functional Properties of Helios+ Regulatory T Cells
Daniel J. Zabransky, Christopher J. Nirschl, Nicholas M. Durham, Ben V. Park, Christina M. Ceccato, Tullia C. Bruno, Ada J. Tam, Derese Getnet, Charles G. Drake
PLoS One. 2012; 7(3): e34547. Published online 2012 Mar 30. doi: 10.1371/journal.pone.0034547
PMCID:
PMC3316700
AbstractArticlePDF–1.0M
6.
Expression of a non–DNA-binding isoform of Helios induces T-cell lymphoma in mice
Zheng Zhang, C. Scott Swindle, John T. Bates, Rose Ko, Claudiu V. Cotta, Christopher A. Klug
Blood. 2007 Mar 1; 109(5): 2190–2197. Prepublished online 2006 Nov 16. doi: 10.1182/blood-2005-01-031930
PMCID:
PMC1801072
AbstractArticle
7.
Helios Expression Is Downregulated on CD8+ Treg in Two Mouse Models of Lupus During Disease Progression
Andrés París-Muñoz, Gonzalo Aizpurua, Domingo F. Barber
Front Immunol. 2022; 13: 922958. Published online 2022 Jun 16. doi: 10.3389/fimmu.2022.922958
PMCID:
PMC9244697
AbstractArticlePDF–6.3M
8.
Helios represses megakaryocyte priming in hematopoietic stem and progenitor cells
Giovanni Cova, Chiara Taroni, Marie-Céline Deau, Qi Cai, Vincent Mittelheisser, Muriel Philipps, Matthieu Jung, Marie Cerciat, Stéphanie Le Gras, Christelle Thibault-Carpentier, Bernard Jost, Leif Carlsson, Angela M. Thornton, Ethan M. Shevach, Peggy Kirstetter, Philippe Kastner, Susan Chan
J Exp Med. 2021 Oct 4; 218(10): e20202317. Published online 2021 Aug 30. doi: 10.1084/jem.20202317
PMCID:
PMC8406645
AbstractArticlePDF–6.9M
9.
Helios: still behind the clouds
Angela M. Thornton, Ethan M. Shevach
Immunology. 2019 Nov; 158(3): 161–170. Published online 2019 Oct 13. doi: 10.1111/imm.13115
PMCID:
PMC6797934
AbstractArticlePDF–721K
10.
Helios Deficiency Predisposes the Differentiation of CD4+Foxp3− T Cells into pTregs
Mathias Skadow, Vinay R. Penna, Jessica Galant-Swafford, Ethan M. Shevach, Angela M. Thornton
J Immunol. Author manuscript; available in PMC 2020 Jul 15.
Published in final edited form as: J Immunol. 2019 Jul 15; 203(2): 370–378. Published online 2019 Jun 5. doi: 10.4049/jimmunol.1900388
PMCID:
PMC6615958
AbstractArticlePDF–1.5M
11.
Comparative transcriptome analysis reveals distinct genetic modules associated with Helios expression in intratumoral regulatory T cells
Kathleen Yates, Kevin Bi, W. Nicholas Haining, Harvey Cantor, Hye-Jung Kim
Proc Natl Acad Sci U S A. 2018 Feb 27; 115(9): 2162–2167. Published online 2018 Feb 9. doi: 10.1073/pnas.1720447115
PMCID:
PMC5834721
AbstractArticlePDF–1.3M
12.
Helios controls a limited subset of regulatory T cell functions
Mathew Sebastian, Maria Lopez-Ocasio, Amina Metidji, Sadiye Amcaoglu Rieder, Ethan M. Shevach, Angela M. Thornton
J Immunol. Author manuscript; available in PMC 2017 Jan 1.
Published in final edited form as: J Immunol. 2016 Jan 1; 196(1): 144–155. Published online 2015 Nov 18. doi: 10.4049/jimmunol.1501704
PMCID:
PMC4685018
AbstractArticlePDF–1.6M
13.
Programmed cell death 1 and Helios distinguish TCR-αβ+ double negative (CD4-CD8-) T cells that derive from self-reactive CD8 T cells
Noé Rodríguez-Rodríguez, Sokratis A. Apostolidis, Pablo Penaloza-MacMaster, José Manuel Martín Villa, Dan H. Barouch, George C. Tsokos, José C. Crispín
J Immunol. Author manuscript; available in PMC 2016 May 1.
Published in final edited form as: J Immunol. 2015 May 1; 194(9): 4207–4214. Published online 2015 Mar 30. doi: 10.4049/jimmunol.1402775
PMCID:
PMC4503929
AbstractArticlePDF–687K
14.
Helios Expression Is a Marker of T Cell Activation and Proliferation
Tatiana Akimova, Ulf H. Beier, Liqing Wang, Matthew H. Levine, Wayne W. Hancock
PLoS One. 2011; 6(8): e24226. Published online 2011 Aug 30. doi: 10.1371/journal.pone.0024226
PMCID:
PMC3168881
AbstractArticlePDF–2.3M
15.
Helios Is Associated with CD4 T Cells Differentiating to T Helper 2 and Follicular Helper T Cells In Vivo Independently of Foxp3 Expression
Karine Serre, Cécile Bénézech, Guillaume Desanti, Saeeda Bobat, Kai-Michael Toellner, Roger Bird, Susan Chan, Philippe Kastner, Adam F. Cunningham, Ian C. M. MacLennan, Elodie Mohr
PLoS One. 2011; 6(6): e20731. Published online 2011 Jun 3. doi: 10.1371/journal.pone.0020731
PMCID:
PMC3108993
AbstractArticlePDF–1.6M
16.
A role for the transcription factor Helios in human CD4+CD25+ regulatory T cells
Derese Getnet, Joseph F. Grosso, Monica V. Goldberg, Timothy J. Harris, Hung-Rong Yen, Tullia C. Bruno, Nicholas M. Durham, Edward L. Hipkiss, Kristin J. Pyle, Satoshi Wada, Fan Pan, Drew M. Pardoll, Charles G. Drake
Mol Immunol. Author manuscript; available in PMC 2011 Apr 1.
Published in final edited form as: Mol Immunol. 2010 Apr; 47(7-8): 1595–1600. Published online 2010 Mar 11. doi: 10.1016/j.molimm.2010.02.001
PMCID:
PMC3060613
AbstractArticlePDF–556K
17.
Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin
Kyungmin Hahm, Bradley S. Cobb, Aaron S. McCarty, Karen E. Brown, Christopher A. Klug, Robert Lee, Koichi Akashi, Irving L. Weissman, Amanda G. Fisher, Stephen T. Smale
Genes Dev. 1998 Mar 15; 12(6): 782–796. doi: 10.1101/gad.12.6.782
PMCID:
PMC316626
AbstractArticlePDF–1.0M
18.
An immunologic mode of multigenerational transmission governs a gut Treg setpoint.
Deepshika Ramanan, Esen Sefik, Silvia Galván-Peña, Meng Wu, Liang Yang, Zhen Yang, Aleksandar Kostic, Tatyana V. Golovkina, Dennis L. Kasper, Diane Mathis, Christophe Benoist
Cell. Author manuscript; available in PMC 2020 Dec 11.
Published in final edited form as: Cell. 2020 Jun 11; 181(6): 1276–1290.e13. Published online 2020 May 12. doi: 10.1016/j.cell.2020.04.030
PMCID:
PMC7393667
AbstractArticlePDF–2.8M
19.
THE GENOMIC LANDSCAPE OF HYPODIPLOID ACUTE LYMPHOBLASTIC LEUKEMIA
Linda Holmfeldt, Lei Wei, Ernesto Diaz-Flores, Michael Walsh, Jinghui Zhang, Li Ding, Debbie Payne-Turner, Michelle Churchman, Anna Andersson, Shann-Ching Chen, Kelly McCastlain, Jared Becksfort, Jing Ma, Gang Wu, Samir N. Patel, Susan L. Heatley, Letha A. Phillips, Guangchun Song, John Easton, Matthew Parker, Xiang Chen, Michael Rusch, Kristy Boggs, Bhavin Vadodaria, Erin Hedlund, Christina Drenberg, Sharyn Baker, Deqing Pei, Cheng Cheng, Robert Huether, Charles Lu, Robert S. Fulton, Lucinda L. Fulton, Yashodhan Tabib, David J. Dooling, Kerri Ochoa, Mark Minden, Ian D. Lewis, L. Bik To, Paula Marlton, Andrew W. Roberts, Gordana Raca, Wendy Stock, Geoffrey Neale, Hans G. Drexler, Ross A. Dickins, David W. Ellison, Sheila A. Shurtleff, Ching-Hon Pui, Raul C. Ribeiro, Meenakshi Devidas, Andrew J. Carroll, Nyla A. Heerema, Brent Wood, Michael J. Borowitz, Julie M. Gastier-Foster, Susana C. Raimondi, Elaine R. Mardis, Richard K. Wilson, James R. Downing, Stephen P. Hunger, Mignon L. Loh, Charles G. Mullighan
Nat Genet. Author manuscript; available in PMC 2014 Feb 10.
Published in final edited form as: Nat Genet. 2013 Mar; 45(3): 242–252. Published online 2013 Jan 20. doi: 10.1038/ng.2532
PMCID:
PMC3919793
AbstractArticlePDF–5.6M
20.
Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells
Angela M. Thornton, Patricia E. Korty, Dat Q. Tran, Elizabeth A. Wohlfert, Patrick E. Murray, Yasmine Belkaid, Ethan M. Shevach
J Immunol. Author manuscript; available in PMC 2013 Jul 29.
Published in final edited form as: J Immunol. 2010 Apr 1; 184(7): 3433–3441. Published online 2010 Feb 24. doi: 10.4049/jimmunol.0904028
PMCID:
PMC3725574
AbstractArticlePDF–3.1M

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