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Select item 37003051.

The Four and a Half LIM Family Members Are Novel Interactants of the Human T-Cell Leukemia Virus Type 1 Tax Oncoprotein

Áine McCabe, Kenichi Hashimoto, William W. Hall, Noreen Sheehy

J Virol. 2013 Jul; 87(13): 7435–7444. doi: 10.1128/JVI.00070-13

PMCID:: PMC3700305

Abstract Article PDF–1.3M

Select item 43201152.

Angiogenin Promotes U87MG Cell Proliferation by Activating NF-κB Signaling Pathway and Downregulating Its Binding Partner FHL3

Wenrong Xia, Wenliang Fu, Xin Cai, Min Wang, Huihua Chen, Weiwei Xing, Yuanyuan Wang, Minji Zou, Tao Xu, Donggang Xu

PLoS One. 2015; 10(2): e0116983. Published online 2015 Feb 6. doi: 10.1371/journal.pone.0116983

PMCID:: PMC4320115

Abstract Article PDF–671K

Select item 39721353.

Identification and Characterization of MT-1X as a Novel FHL3-Binding Partner

Xin Cai, JinFeng Wang, Xin Huang, Wenliang Fu, Wenrong Xia, Minji Zou, YuanYuan Wang, Jiaxi Wang, Donggang Xu

PLoS One. 2014; 9(4): e93723. Published online 2014 Apr 1. doi: 10.1371/journal.pone.0093723

PMCID:: PMC3972135

Abstract Article PDF–682K

Select item 82130274.

FHL3 Contributes to EMT and Chemotherapy Resistance Through Up-Regulation of Slug and Activation of TGFβ/Smad-Independent Pathways in Gastric Cancer

Guodong Cao, Pengping Li, Xiaobo He, Mengyao Jin, Mengying Li, Sihan Chen, Xin Xu, Qiang Sun, Maoming Xiong, Bo Chen

Front Oncol. 2021; 11: 649029. Published online 2021 Jun 4. doi: 10.3389/fonc.2021.649029

PMCID:: PMC8213027

Abstract Article PDF–12M

Select item 71665205.

PCBP2 promotes the development of glioma by regulating FHL3/TGF‐β/Smad signaling pathway

Jianhui Mao, Zhaosheng Sun, Yongjian Cui, Naiyi Du, Hong Guo, Jianhui Wei, Zhenmin Hao, Lei Zheng

J Cell Physiol. 2020 Apr; 235(4): 3280–3291. Published online 2019 Nov 6. doi: 10.1002/jcp.29104

PMCID:: PMC7166520

Abstract Article PDF–3.6M

Select item 64620056.

FHL3 links cell growth and self-renewal by modulating SOX4 in glioma

Wei Han, Peishan Hu, Fan Wu, Shanshan Wang, Yan Hu, Shanshan Li, Tao Jiang, Boqin Qiang, Xiaozhong Peng

Cell Death Differ. 2019 May; 26(5): 796–811. Published online 2018 Jun 28. doi: 10.1038/s41418-018-0152-1

PMCID:: PMC6462005

Abstract Article PDF–4.3M

Select item 3214377.

Extracellular Signal-Regulated Kinase 2 Interacts with and Is Negatively Regulated by the LIM-Only Protein FHL2 in Cardiomyocytes

Nicole H. Purcell, Dina Darwis, Orlando F. Bueno, Judith M. Müller, Roland Schüle, Jeffery D. Molkentin

Mol Cell Biol. 2004 Feb; 24(3): 1081–1095. doi: 10.1128/MCB.24.3.1081-1095.2004

PMCID:: PMC321437

Abstract Article PDF–806K

Select item 11347818.

FHL3 negatively regulates human high-affinity IgE receptor β-chain gene expression by acting as a transcriptional co-repressor of MZF-1

Kyoko Takahashi, Chiyuki Matsumoto, Chisei Ra

Biochem J. 2005 Feb 15; 386(Pt 1): 191–200. Prepublished online 2004 Sep 29. Published online 2005 Feb 8. doi: 10.1042/BJ20040775

PMCID:: PMC1134781

Abstract Article PDF–630K

Select item 33072739.

Four-and-a-Half LIM Domain Proteins Inhibit Transactivation by Hypoxia-inducible Factor 1

Maimon E. Hubbi, Daniele M. Gilkes, Jin H. Baek, Gregg L. Semenza

J Biol Chem. 2012 Feb 24; 287(9): 6139–6149. Published online 2012 Jan 4. doi: 10.1074/jbc.M111.278630

PMCID:: PMC3307273

Abstract Article PDF–3.6M

Select item 10216610.

A Family of LIM-Only Transcriptional Coactivators: Tissue-Specific Expression and Selective Activation of CREB and CREM

Gian Maria Fimia, Dario De Cesare, Paolo Sassone-Corsi

Mol Cell Biol. 2000 Nov; 20(22): 8613–8622. doi: 10.1128/mcb.20.22.8613-8622.2000

PMCID:: PMC102166

Abstract Article PDF–2.8M

Select item 263129311.

Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-β–like signaling pathway

Lihua Ding, Zhaoyun Wang, Jinghua Yan, Xiao Yang, Aijun Liu, Weiyi Qiu, Jianhua Zhu, Juqiang Han, Hao Zhang, Jing Lin, Long Cheng, Xi Qin, Chang Niu, Bin Yuan, Xiaohui Wang, Cui Zhu, Yan Zhou, Jiezhi Li, Haifeng Song, Cuifen Huang, Qinong Ye

J Clin Invest. 2009 Feb 2; 119(2): 349–361. Published online 2009 Jan 12. doi: 10.1172/JCI35930

PMCID:: PMC2631293

Abstract Article PDF–4.1M

Select item 524758112.

A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity

Xiaojie Xu, Zhongyi Fan, Chaoyang Liang, Ling Li, Lili Wang, Yingchun Liang, Jun Wu, Shaohong Chang, Zhifeng Yan, Zhaohui Lv, Jing Fu, Yang Liu, Shuai Jin, Tao Wang, Tian Hong, Yishan Dong, Lihua Ding, Long Cheng, Rui Liu, Shenbo Fu, Shunchang Jiao, Qinong Ye

Nat Commun. 2017; 8: 14059. Published online 2017 Jan 17. doi: 10.1038/ncomms14059

PMCID:: PMC5247581

Abstract Article PDF–4.9M

Select item 330886413.

Ubiquitin Ligase Substrate Identification through Quantitative Proteomics at Both the Protein and Peptide Levels

Kimberly A. Lee, Lisa P. Hammerle, Paul S. Andrews, Matthew P. Stokes, Tomas Mustelin, Jeffrey C. Silva, Roy A. Black, John R. Doedens

J Biol Chem. 2011 Dec 2; 286(48): 41530–41538. Published online 2011 Oct 10. doi: 10.1074/jbc.M111.248856

PMCID:: PMC3308864

Abstract Article PDF–815K

Select item 507651914.

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development

Yen-Fu Cheng, Mingjie Tong, Albert S. B. Edge

J Biol Chem. 2016 Sep 30; 291(40): 21096–21109. Published online 2016 Aug 19. doi: 10.1074/jbc.M116.722124

PMCID:: PMC5076519

Abstract Article PDF–3.4M

Select item 1008090815.

The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/Arkadia

Sadek Amhaz, Batiste Boëda, Mouna Chouchène, Sabrina Colasse, Florent Dingli, Damarys Loew, Julien Henri, Céline Prunier, Laurence Levy

BMC Biol. 2023; 21: 73. Published online 2023 Apr 7. doi: 10.1186/s12915-023-01576-4

PMCID:: PMC10080908

Abstract Article PDF–3.2M

Select item 341884416.

Methods for Quantification of in vivo Changes in Protein Ubiquitination following Proteasome and Deubiquitinase Inhibition

Namrata D. Udeshi, D. R. Mani, Thomas Eisenhaure, Philipp Mertins, Jacob D. Jaffe, Karl R. Clauser, Nir Hacohen, Steven A. Carr

Mol Cell Proteomics. 2012 May; 11(5): 148–159. Published online 2012 Apr 14. doi: 10.1074/mcp.M111.016857

PMCID:: PMC3418844

Abstract Article PDF–1.5M

Select item 613866017.

rec-YnH enables simultaneous many-by-many detection of direct protein–protein and protein–RNA interactions

Jae-Seong Yang, Mireia Garriga-Canut, Nele Link, Carlo Carolis, Katrina Broadbent, Violeta Beltran-Sastre, Luis Serrano, Sebastian P. Maurer

Nat Commun. 2018; 9: 3747. Published online 2018 Sep 14. doi: 10.1038/s41467-018-06128-x

PMCID:: PMC6138660

Abstract Article PDF–1.9M

Select item 320587618.

A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles

Sebastian A. Wagner, Petra Beli, Brian T. Weinert, Michael L. Nielsen, Jürgen Cox, Matthias Mann, Chunaram Choudhary

Mol Cell Proteomics. 2011 Oct; 10(10): M111.013284. Published online 2011 Sep 1. doi: 10.1074/mcp.M111.013284

PMCID:: PMC3205876

Abstract Article PDF–4.8M

Select item 304715219.

Mass Spectrometric Analysis of Lysine Ubiquitylation Reveals Promiscuity at Site Level

Jannie M. R. Danielsen, Kathrine B. Sylvestersen, Simon Bekker-Jensen, Damian Szklarczyk, Jon W. Poulsen, Heiko Horn, Lars J. Jensen, Niels Mailand, Michael L. Nielsen

Mol Cell Proteomics. 2011 Mar; 10(3): M110.003590. Published online 2010 Dec 7. doi: 10.1074/mcp.M110.003590

PMCID:: PMC3047152

Abstract Article PDF–2.9M

Select item 660120820.

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18

Manal Alsulami, Nayla Munawar, Eugene Dillon, Giorgio Oliviero, Kieran Wynne, Mona Alsolami, Catherine Moss, Peadar Ó Gaora, Fergal O'Meara, David Cotter, Gerard Cagney

Mol Cell Proteomics. 2019 Jul; 18(7): 1428–1436. Published online 2019 May 10. doi: 10.1074/mcp.RA119.001518