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Select item 112714471.

Decrease in UCP1 by sustained high lipid promotes NK cell necroptosis to exacerbate nonalcoholic liver fibrosis

Min Gu, Yu Zhang, Zhijie Lin, Xiangyu Hu, Yaqin Zhu, Weiming Xiao, Xiaoqin Jia, Weiwei Chen, Guotao Lu, Weijuan Gong

Cell Death Dis. 2024 Jul; 15(7): 518. Published online 2024 Jul 20. doi: 10.1038/s41419-024-06910-4

PMCID:: PMC11271447

Abstract Article PDF–7.2M

Select item 111572642.

Mitochondrial lipidomes are tissue specific – low cholesterol contents relate to UCP1 activity

Sarah Brunner, Marcus Höring, Gerhard Liebisch, Sabine Schweizer, Josef Scheiber, Piero Giansanti, Maria Hidrobo, Sven Hermeling, Josef Oeckl, Natalia Prudente de Mello, Fabiana Perocchi, Claudine Seeliger, Akim Strohmeyer, Martin Klingenspor, Johannes Plagge, Bernhard Küster, Ralph Burkhardt, Klaus-Peter Janssen, Josef Ecker

Life Sci Alliance. 2024 Aug; 7(8): e202402828. Published online 2024 Jun 6. doi: 10.26508/lsa.202402828

PMCID:: PMC11157264

Abstract Article PDF–3.4M

Select item 109441063.

Differential responses to UCP1 ablation in classical brown versus beige fat, despite a parallel increase in sympathetic innervation

Qimuge Naren, Erik Lindsund, Muhammad Hamza Bokhari, Weijun Pang, Natasa Petrovic

J Biol Chem. 2024 Mar; 300(3): 105760. Published online 2024 Feb 16. doi: 10.1016/j.jbc.2024.105760

PMCID:: PMC10944106

Abstract Article PDF–9.1M

Select item 102435374.

Oxaloacetate regulates complex II respiration in brown fat: dependence on UCP1 expression

Ritu Som, Brian D. Fink, Liping Yu, William I. Sivitz

Am J Physiol Cell Physiol. 2023 Jun 1; 324(6): C1236–C1248. Published online 2023 May 1. doi: 10.1152/ajpcell.00565.2022

PMCID:: PMC10243537

Abstract Article

Select item 102182475.

Temperature-Dependent Effects of Eicosapentaenoic Acid (EPA) on Browning of Subcutaneous Adipose Tissue in UCP1 Knockout Male Mice

Yujiao Zu, Mandana Pahlavani, Latha Ramalingam, Shasika Jayarathne, Jose Andrade, Shane Scoggin, William T. Festuccia, Nishan S. Kalupahana, Naima Moustaid-Moussa

Int J Mol Sci. 2023 May; 24(10): 8708. Published online 2023 May 13. doi: 10.3390/ijms24108708

PMCID:: PMC10218247

Abstract Article PDF–3.4M

Select item 99321776.

Regulation of beige adipocyte thermogenesis by the cold-repressed ER protein NNAT

Kyung-Mi Choi, Christopher Y. Ko, Sung-Min An, Seung-Hee Cho, Douglas J. Rowland, Jung Hak Kim, Anna Fasoli, Abhijit J. Chaudhari, Donald M. Bers, John C. Yoon

Mol Metab. 2023 Mar; 69: 101679. Published online 2023 Jan 25. doi: 10.1016/j.molmet.2023.101679

PMCID:: PMC9932177

Abstract Article PDF–3.0M

Select item 99170617.

Deletion of UCP1 in Tg2576 Mice Increases Body Temperature and Exacerbates Alzheimer’s Disease-Related Pathologies

Cha-Gyun Jung, Hitoshi Yamashita, Reiko Kato, Chunyu Zhou, Hiroaki Matsushita, Tamaki Takeuchi, Mona Abdelhamid, Yuxin Chen, Makoto Michikawa

Int J Mol Sci. 2023 Feb; 24(3): 2741. Published online 2023 Feb 1. doi: 10.3390/ijms24032741

PMCID:: PMC9917061

Abstract Article PDF–5.0M

Select item 97728558.

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle

Jinit Masania, Patrick Wijten, Susanne Keipert, Mario Ost, Susanne Klaus, Naila Rabbani, Paul J. Thornalley

Redox Biol. 2023 Feb; 59: 102574. Published online 2022 Dec 6. doi: 10.1016/j.redox.2022.102574

PMCID:: PMC9772855

Abstract Article PDF–2.9M

Select item 95464489.

Uncoupling Protein-1 Modulates Anxiety-Like Behavior in a Temperature-Dependent Manner

Spyridon Sideromenos, Anna Gundacker, Maria Nikou, Raimund Oberle, Orsolya Horvath, Peter Stoehrmann, Timo Partonen, Daniela D. Pollak

J Neurosci. 2022 Oct 5; 42(40): 7659–7672. doi: 10.1523/JNEUROSCI.2509-21.2022

PMCID:: PMC9546448

Abstract Article PDF–2.1M

Select item 932229710.

AMP‐activated protein kinase activation in skeletal muscle modulates exercise‐induced uncoupled protein 1 expression in brown adipocyte in mouse model

Hye Jin Kim, Youn Ju Kim, Je Kyung Seong

J Physiol. 2022 May 15; 600(10): 2359–2376. Published online 2022 Apr 5. doi: 10.1113/JP282999

PMCID:: PMC9322297

Abstract Article PDF–1.4M

Select item 909761511.

Loss of UCP1 function augments recruitment of futile lipid cycling for thermogenesis in murine brown fat

Josef Oeckl, Petra Janovska, Katerina Adamcova, Kristina Bardova, Sarah Brunner, Sebastian Dieckmann, Josef Ecker, Tobias Fromme, Jiri Funda, Thomas Gantert, Piero Giansanti, Maria Soledad Hidrobo, Ondrej Kuda, Bernhard Kuster, Yongguo Li, Radek Pohl, Sabine Schmitt, Sabine Schweizer, Hans Zischka, Petr Zouhar, Jan Kopecky, Martin Klingenspor

Mol Metab. 2022 Jul; 61: 101499. Published online 2022 Apr 22. doi: 10.1016/j.molmet.2022.101499

PMCID:: PMC9097615

Abstract Article PDF–3.0M

Select item 873231712.

Cysteine 253 of UCP1 regulates energy expenditure and sex-dependent adipose tissue inflammation

Evanna L. Mills, Cathal Harmon, Mark P. Jedrychowski, Haopeng Xiao, Anja V. Gruszczyk, Gary A. Bradshaw, Nhien Tran, Ryan Garrity, Dina Laznik-Bogoslavski, John Szpyt, Hannah Prendeville, Lydia Lynch, Michael P. Murphy, Steven P. Gygi, Bruce M. Spiegelman, Edward T. Chouchani

Cell Metab. Author manuscript; available in PMC 2023 Jan 4.

Published in final edited form as: Cell Metab. 2022 Jan 4; 34(1): 140–157.e8. Published online 2021 Dec 2. doi: 10.1016/j.cmet.2021.11.003

PMCID:: PMC8732317

Abstract Article PDF–1.4M

Select item 853327613.

Fatty Acids Rescue the Thermogenic Function of Sympathetically Denervated Brown Fat

Qiang Cao, Shirong Wang, Huan Wang, Xin Cui, Jia Jing, Liqing Yu, Hang Shi, Bingzhong Xue

Biomolecules. 2021 Oct; 11(10): 1428. Published online 2021 Sep 29. doi: 10.3390/biom11101428

PMCID:: PMC8533276

Abstract Article PDF–4.4M

Select item 845556314.

Isothermal microcalorimetry measures UCP1-mediated thermogenesis in mature brite adipocytes

Muhammad Hamza Bokhari, Carina Halleskog, Alice Åslund, Nathalie Boulet, Eva Casadesús Rendos, Jasper Martin Anton de Jong, Robert Csikasz, Ez-Zoubir Amri, Irina Shabalina, Tore Bengtsson

Commun Biol. 2021; 4: 1108. Published online 2021 Sep 21. doi: 10.1038/s42003-021-02639-4

PMCID:: PMC8455563

Abstract Article PDF–1.9M

Select item 845279915.

A pyrexic effect of FGF21 independent of energy expenditure and UCP1

Petr Zouhar, Petra Janovska, Sara Stanic, Kristina Bardova, Jiri Funda, Blanka Haberlova, Birgitte Andersen, Martin Rossmeisl, Barbara Cannon, Jan Kopecky, Jan Nedergaard

Mol Metab. 2021 Nov; 53: 101324. Published online 2021 Aug 19. doi: 10.1016/j.molmet.2021.101324

PMCID:: PMC8452799

Abstract Article PDF–4.1M

Select item 844370216.

Contrasting recruitment of skin-associated adipose depots during cold challenge of mouse and human

Ildiko Kasza, Jens-Peter Kühn, Henry Völzke, Diego Hernando, Yaohui G. Xu, John W. Siebert, Angela LF Gibson, C.-L. Eric Yen, David W. Nelson, Ormond A. MacDougald, Nicole E. Richardson, Dudley W. Lamming, Philip A. Kern, CM Alexander

J Physiol. Author manuscript; available in PMC 2023 Feb 1.

Published in final edited form as: J Physiol. 2022 Feb; 600(4): 847–868. Published online 2021 Apr 15. doi: 10.1113/JP280922

PMCID:: PMC8443702

Abstract Article PDF–3.9M

Select item 803648517.

Pseudo-Starvation Driven Energy Expenditure Negatively Affects Ovarian Follicle Development

Li Meng, Verena Coleman, Yu Zhao, Mario Ost, Anja Voigt, Annelies Bunschoten, Jaap Keijer, Katja Teerds, Susanne Klaus

Int J Mol Sci. 2021 Apr; 22(7): 3557. Published online 2021 Mar 30. doi: 10.3390/ijms22073557

PMCID:: PMC8036485

Abstract Article PDF–3.2M

Select item 797831618.

Relieving lipid accumulation through UCP1 suppresses the progression of acute kidney injury by promoting the AMPK/ULK1/autophagy pathway

Wei Xiong, Zhiyong Xiong, Anni Song, Chuntao Lei, Chen Ye, Chun Zhang

Theranostics. 2021; 11(10): 4637–4654. Published online 2021 Mar 4. doi: 10.7150/thno.56082

PMCID:: PMC7978316

Abstract Article PDF–4.5M

Select item 791053719.

An improved method for the precise unravelment of non-shivering brown fat thermokinetics

Rebecca Oelkrug, Jens Mittag

Sci Rep. 2021; 11: 4799. Published online 2021 Feb 26. doi: 10.1038/s41598-021-84200-1

PMCID:: PMC7910537

Abstract Article PDF–4.1M

Select item 772326920.

Identification and characterization of distinct brown adipocyte subtypes in C57BL/6J mice

Ruth Karlina, Dominik Lutter, Viktorian Miok, David Fischer, Irem Altun, Theresa Schöttl, Kenji Schorpp, Andreas Israel, Cheryl Cero, James W Johnson, Ingrid Kapser-Fischer, Anika Böttcher, Susanne Keipert, Annette Feuchtinger, Elisabeth Graf, Tim Strom, Axel Walch, Heiko Lickert, Thomas Walzthoeni, Matthias Heinig, Fabian J Theis, Cristina García-Cáceres, Aaron M Cypess, Siegfried Ussar

Life Sci Alliance. 2021 Jan; 4(1): e202000924. Published online 2020 Nov 30. doi: 10.26508/lsa.202000924

PMCID:: PMC7723269

Abstract Article PDF–8.1M

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