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Items: 1 to 20 of 29

1.
Interactions between TULP3 tubby domain and ARL13B amphipathic helix promote lipidated protein transport to cilia
Vivek Reddy Palicharla, Sun-Hee Hwang, Bandarigoda N. Somatilaka, Emilie Legué, Issei S. Shimada, Nicole E. Familiari, Vanna M. Tran, Jeffrey B. Woodruff, Karel F. Liem, Jr., Saikat Mukhopadhyay
Mol Biol Cell. 2023 Mar 1; 34(3): ar18. Published online 2023 Feb 21. doi: 10.1091/mbc.E22-10-0473
PMCID:
PMC10011728
AbstractArticlePDF–17M
2.
Mutations in ciliary trafficking genes affect Shh-dependent neural tube patterning differentially along the A-P axis.
Emilie Legué, Karel F. Liem, Jr.
Neuroscience. Author manuscript; available in PMC 2021 Dec 1.
Published in final edited form as: Neuroscience. 2020 Dec 1; 450: 3–14. Published online 2020 Jul 16. doi: 10.1016/j.neuroscience.2020.07.015
PMCID:
PMC7688495
AbstractArticlePDF–2.7M
3.
BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone
Fan Ye, Andrew R. Nager, Maxence V. Nachury
J Cell Biol. 2018 May 7; 217(5): 1847–1868. doi: 10.1083/jcb.201709041
PMCID:
PMC5940304
AbstractArticlePDF–3.4M
4.
Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling
Francesc R. Garcia-Gonzalo, Siew C. Phua, Elle C. Roberson, Galo Garcia, III, Monika Abedin, Stéphane Schurmans, Takanari Inoue, Jeremy F. Reiter
Dev Cell. Author manuscript; available in PMC 2016 Aug 24.
Published in final edited form as: Dev Cell. 2015 Aug 24; 34(4): 400–409. doi: 10.1016/j.devcel.2015.08.001
PMCID:
PMC4557815
AbstractArticlePDF–1.2M
5.
Omega-3 fatty acids activate ciliary FFAR4 to control adipogenesis
Keren I. Hilgendorf, Carl T. Johnson, Anja Mezger, Selena L. Rice, Alessandra M. Norris, Janos Demeter, William J. Greenleaf, Jeremy F. Reiter, Daniel Kopinke, Peter K. Jackson
Cell. Author manuscript; available in PMC 2020 Nov 27.
Published in final edited form as: Cell. 2019 Nov 27; 179(6): 1289–1305.e21. Published online 2019 Nov 21. doi: 10.1016/j.cell.2019.11.005
PMCID:
PMC7332222
AbstractArticlePDF–3.7M
6.
The Ciliary Protein Arl13b Functions Outside of the Primary Cilium in Shh-Mediated Axon Guidance
Julien Ferent, Sandii Constable, Eduardo D. Gigante, Patricia T. Yam, Laura E. Mariani, Emilie Legué, Karel F. Liem, Jr., Tamara Caspary, Frédéric Charron
Cell Rep. Author manuscript; available in PMC 2019 Dec 23.
Published in final edited form as: Cell Rep. 2019 Dec 10; 29(11): 3356–3366.e3. doi: 10.1016/j.celrep.2019.11.015
PMCID:
PMC6927553
AbstractArticlePDF–1.7M
7.
Tulp3 regulates renal cystogenesis by trafficking of cystoproteins to cilia
Sun-Hee Hwang, Bandarigoda N. Somatilaka, Hemant Badgandi, Vivek Reddy Palicharla, Rebecca Walker, John M. Shelton, Feng Qian, Saikat Mukhopadhyay
Curr Biol. Author manuscript; available in PMC 2020 Mar 4.
Published in final edited form as: Curr Biol. 2019 Mar 4; 29(5): 790–802.e5. Published online 2019 Feb 21. doi: 10.1016/j.cub.2019.01.047
PMCID:
PMC6401225
AbstractArticlePDF–4.0M
8.
Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function
Chen-Jei Hong, Bruce A. Hamilton
PLoS Genet. 2016 Oct; 12(10): e1006357. Published online 2016 Oct 11. doi: 10.1371/journal.pgen.1006357
PMCID:
PMC5065120
AbstractArticlePDF–2.4M
9.
The ciliary phosphatidylinositol phosphatase Inpp5e plays positive and negative regulatory roles in Shh signaling
Sandii Constable, Alyssa B. Long, Katharine A. Floyd, Stéphane Schurmans, Tamara Caspary
Development. 2020 Feb 1; 147(3): dev183301. Published online 2020 Feb 3. doi: 10.1242/dev.183301
PMCID:
PMC7033722
AbstractArticle
10.
Gata6-Dependent GLI3 Repressor Function is Essential in Anterior Limb Progenitor Cells for Proper Limb Development
Shinichi Hayashi, Ryutaro Akiyama, Julia Wong, Naoyuki Tahara, Hiroko Kawakami, Yasuhiko Kawakami
PLoS Genet. 2016 Jun; 12(6): e1006138. Published online 2016 Jun 28. doi: 10.1371/journal.pgen.1006138
PMCID:
PMC4924869
AbstractArticlePDF–13M
11.
Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway
Victoria L. Patterson, Christine Damrau, Anju Paudyal, Benjamin Reeve, Daniel T. Grimes, Michelle E. Stewart, Debbie J. Williams, Pam Siggers, Andy Greenfield, Jennifer N. Murdoch
Hum Mol Genet. 2009 May 15; 18(10): 1719–1739. Published online 2009 Feb 17. doi: 10.1093/hmg/ddp075
PMCID:
PMC2671985
AbstractArticlePDF–1.0M
12.
TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia
Saikat Mukhopadhyay, Xiaohui Wen, Ben Chih, Christopher D. Nelson, William S. Lane, Suzie J. Scales, Peter K. Jackson
Genes Dev. 2010 Oct 1; 24(19): 2180–2193. doi: 10.1101/gad.1966210
PMCID:
PMC2947770
AbstractArticlePDF–1.9M
13.
Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling
Ryan X. Norman, Hyuk W. Ko, Viola Huang, Christine M. Eun, Lisa L. Abler, Zhen Zhang, Xin Sun, Jonathan T. Eggenschwiler
Hum Mol Genet. 2009 May 15; 18(10): 1740–1754. Published online 2009 Mar 12. doi: 10.1093/hmg/ddp113
PMCID:
PMC2671991
AbstractArticlePDF–640K
14.
Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components
Jian Qin, Yulian Lin, Ryan X. Norman, Hyuk W. Ko, Jonathan T. Eggenschwiler
Proc Natl Acad Sci U S A. 2011 Jan 25; 108(4): 1456–1461. Published online 2011 Jan 5. doi: 10.1073/pnas.1011410108
PMCID:
PMC3029728
AbstractArticlePDF–1023K
15.
Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins
Hemant B. Badgandi, Sun-hee Hwang, Issei S. Shimada, Evan Loriot, Saikat Mukhopadhyay
J Cell Biol. 2017 Mar 6; 216(3): 743–760. doi: 10.1083/jcb.201607095
PMCID:
PMC5350516
AbstractArticlePDF–3.1M
16.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
17.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
18.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
19.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
20.
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray
Tetsuya S. Tanaka, Saied A. Jaradat, Meng K. Lim, George J. Kargul, Xiaohong Wang, Marija J. Grahovac, Serafino Pantano, Yuri Sano, Yulan Piao, Ramaiah Nagaraja, Hirofumi Doi, William H. Wood, III, Kevin G. Becker, Minoru S. H. Ko
Proc Natl Acad Sci U S A. 2000 Aug 1; 97(16): 9127–9132. doi: 10.1073/pnas.97.16.9127
PMCID:
PMC16833
AbstractArticlePDF–847K

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