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Select item 108509221.

TERT mediates the U‐shape of glucocorticoids effects in modulation of hippocampal neural stem cells and associated brain function

Meng‐Ying Liu, Yixin Fan, Ningjie Ni, Tao Yu, Zhiyuan Mao, Hanyu Huang, Jing Zhang, Yulin Tang, Hongliang He, Fan Meng, Yongping You, Qi‐Gang Zhou

CNS Neurosci Ther. 2024 Feb; 30(2): e14577. Published online 2024 Feb 7. doi: 10.1111/cns.14577

PMCID:: PMC10850922

Abstract Article PDF–39M

Select item 106377952.

The Wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of TERT: an in vivo and in vitro study

Yuanqing Cai, Huijun Sun, Xingyu Song, Jianyu Zhao, Dong Xu, Mozhen Liu

Aging (Albany NY) 2023 Oct 31; 15(20): 11471–11488. Published online 2023 Oct 19. doi: 10.18632/aging.205136

PMCID:: PMC10637795

Abstract Article PDF–2.6M

Select item 100059583.

Prenatal stress modulates HPA axis homeostasis of offspring through dentate TERT independently of glucocorticoids receptor

Meng-Ying Liu, Lu-Lu Wei, Xian-Hui Zhu, Hua-Chen Ding, Xiang-Hu Liu, Huan Li, Yuan-Yuan Li, Zhou Han, Lian-Di Li, Zi-Wei Du, Ya-Ping Zhou, Jing Zhang, Fan Meng, Yu-Lin Tang, Xiao Liu, Chun Wang, Qi-Gang Zhou

Mol Psychiatry. 2023; 28(3): 1383–1395. Published online 2022 Dec 8. doi: 10.1038/s41380-022-01898-9

PMCID:: PMC10005958

Abstract Article PDF–4.3M

Select item 81350114.

Short and dysfunctional telomeres protect from allergen‐induced airway inflammation

Sergio Piñeiro‐Hermida, Paula Martínez, Maria A. Blasco

Aging Cell. 2021 May; 20(5): e13352. Published online 2021 May 4. doi: 10.1111/acel.13352

PMCID:: PMC8135011

Abstract Article PDF–4.6M

Select item 79861565.

Telomerase expression marks transitional growth‐associated skeletal progenitor/stem cells

Diana L. Carlone, Rebecca D. Riba‐Wolman, Luke T. Deary, Alessio Tovaglieri, Lijie Jiang, Dana M. Ambruzs, Benjamin E. Mead, Manasvi S. Shah, Christopher J. Lengner, Rudolf Jaenisch, David T. Breault

Stem Cells. 2021 Mar; 39(3): 296–305. Published online 2021 Jan 13. doi: 10.1002/stem.3318

PMCID:: PMC7986156

Abstract Article PDF–9.5M

Select item 76046206.

Re‐equilibration of imbalanced NAD metabolism ameliorates the impact of telomere dysfunction

Chongkui Sun, Kun Wang, Amanda J Stock, Yi Gong, Tyler G Demarest, Beimeng Yang, Neelam Giri, Lea Harrington, Blanche P Alter, Sharon A Savage, Vilhelm A Bohr, Yie Liu

EMBO J. 2020 Nov 2; 39(21): e103420. Published online 2020 Sep 16. doi: 10.15252/embj.2019103420

PMCID:: PMC7604620

Abstract Article PDF–5.0M

Select item 67303497.

Ectopic Expression of the Catalytic Subunit of Telomerase Protects against Brain Injury Resulting from Ischemia and NMDA-Induced Neurotoxicity

Hyo Jung Kang, Yoon Sik Choi, Seung-Beom Hong, Kee-Won Kim, Ran-Sook Woo, Seok Joon Won, Eun Ju Kim, Hee Kyung Jeon, So-Young Jo, Tae Kook Kim, Robert Bachoo, Ian J. Reynolds, Byoung Joo Gwag, Han-Woong Lee

J Neurosci. 2004 Feb 11; 24(6): 1280–1287. doi: 10.1523/JNEUROSCI.4082-03.2004

PMCID:: PMC6730349

Abstract Article PDF–307K

Select item 66232218.

Hippocampal Telomerase Is Involved in the Modulation of Depressive Behaviors

Qi-Gang Zhou, Yao Hu, Dan-Lian Wu, Li-Juan Zhu, Chen Chen, Xing Jin, Chun-Xia Luo, Hai-Yin Wu, Jing Zhang, Dong-Ya Zhu

J Neurosci. 2011 Aug 24; 31(34): 12258–12269. doi: 10.1523/JNEUROSCI.0805-11.2011

PMCID:: PMC6623221

Abstract Article PDF–2.6M

Select item 65524229.

Telomerase reverse transcriptase ameliorates lung fibrosis by protecting alveolar epithelial cells against senescence

Tianju Liu, Francina Gonzalez De Los Santos, Yuyue Zhao, Zhe Wu, Andrew E. Rinke, Kevin K. Kim, Sem H. Phan

J Biol Chem. 2019 May 31; 294(22): 8861–8871. Published online 2019 Apr 18. doi: 10.1074/jbc.RA118.006615

PMCID:: PMC6552422

Abstract Article PDF–1.8M

Select item 574150310.

Telomerase enzyme deficiency promotes metabolic dysfunction in murine hepatocytes upon dietary stress

Raquel M. Alves-Paiva, Sachiko Kajigaya, Xingmin Feng, Jichun Chen, Marie Desierto, Susan Wong, Danielle M. Townsley, Flávia S. Donaires, Adeline Bertola, Bin Gao, Neal S. Young, Rodrigo T. Calado

Liver Int. Author manuscript; available in PMC 2019 Jan 1.

Published in final edited form as: Liver Int. 2018 Jan; 38(1): 144–154. Published online 2017 Aug 19. doi: 10.1111/liv.13529

PMCID:: PMC5741503

Abstract Article PDF–1.6M

Select item 567679111.

A method for measuring the distribution of the shortest telomeres in cells and tissues

Tsung-Po Lai, Ning Zhang, Jungsik Noh, Ilgen Mender, Enzo Tedone, Ejun Huang, Woodring E. Wright, Gaudenz Danuser, Jerry W. Shay

Nat Commun. 2017; 8: 1356. Published online 2017 Nov 7. doi: 10.1038/s41467-017-01291-z

PMCID:: PMC5676791

Abstract Article PDF–1.9M

Select item 555002912.

Hippocampal TERT Regulates Spatial Memory Formation through Modulation of Neural Development

Qi-Gang Zhou, Meng-Ying Liu, Han-Woong Lee, Fuyuki Ishikawa, Sushil Devkota, Xin-Ru Shen, Xin Jin, Hai-Yin Wu, Zhigang Liu, Xiao Liu, Xun Jin, Hai-Hui Zhou, Eun Jeoung Ro, Jing Zhang, Yu Zhang, Yu-Hui Lin, Hoonkyo Suh, Dong-Ya Zhu

Stem Cell Reports. 2017 Aug 8; 9(2): 543–556. Published online 2017 Jul 27. doi: 10.1016/j.stemcr.2017.06.014

PMCID:: PMC5550029

Abstract Article PDF–4.8M

Select item 493160413.

Reactivation of Tert in the medial prefrontal cortex and hippocampus rescues aggression and depression of Tert^−/− mice

Q-G Zhou, H-Y Wu, H Zhou, M-Y Liu, H-W Lee, X Liu, S Devkota, E J Ro, D-Y Zhu, H Suh

Transl Psychiatry. 2016 Jun; 6(6): e836. Published online 2016 Jun 14. doi: 10.1038/tp.2016.106

PMCID:: PMC4931604

Abstract Article PDF–3.3M

Select item 487123014.

Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction

Christian Bär, Bruno Bernardes de Jesus, Rosa Serrano, Agueda Tejera, Eduard Ayuso, Veronica Jimenez, Ivan Formentini, Maria Bobadilla, Jacques Mizrahi, Alba de Martino, Gonzalo Gomez, David Pisano, Francisca Mulero, Kai C. Wollert, Fatima Bosch, Maria A. Blasco

Nat Commun. Author manuscript; available in PMC 2016 May 18.

Published in final edited form as: Nat Commun. 2014; 5: 5863. Published online 2014 Dec 18. doi: 10.1038/ncomms6863

PMCID:: PMC4871230

Abstract Article PDF–6.4M

Select item 481696415.

The mouse endometrium contains epithelial, endothelial and leucocyte populations expressing the stem cell marker telomerase reverse transcriptase

James A. Deane, Y. Rue Ong, Jason E. Cain, W. Samantha N. Jayasekara, Abhilasha Tiwari, Diana L. Carlone, D. Neil Watkins, David T. Breault, Caroline E. Gargett

Mol Hum Reprod. 2016 Apr; 22(4): 272–284. Published online 2016 Jan 5. doi: 10.1093/molehr/gav076

PMCID:: PMC4816964

Abstract Article PDF–1.7M

Select item 479279716.

Excitotoxic and Radiation Stress Increase TERT Levels in the Mitochondria and Cytosol of Cerebellar Purkinje Neurons

Erez Eitan, Carmal Braverman, Ailone Tichon, Daniel Gitler, Emmette R. Hutchison, Mark P. Mattson, Esther Priel

Cerebellum. Author manuscript; available in PMC 2017 Aug 1.

Published in final edited form as: Cerebellum. 2016 Aug; 15(4): 509–517. doi: 10.1007/s12311-015-0720-6

PMCID:: PMC4792797

Abstract Article PDF–852K

Select item 464070617.

Conditional Knockout of Telomerase Reverse Transcriptase in Mesenchymal Cells Impairs Mouse Pulmonary Fibrosis

Tianju Liu, Hongfeng Yu, Lin Ding, Zhe Wu, Francina Gonzalez De Los Santos, Jianhua Liu, Matthew Ullenbruch, Biao Hu, Vanessa Martins, Sem H. Phan

PLoS One. 2015; 10(11): e0142547. Published online 2015 Nov 10. doi: 10.1371/journal.pone.0142547

PMCID:: PMC4640706

Abstract Article PDF–2.1M

Select item 448984218.

Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice

Aparna Raval, Gregory K. Behbehani, Le Xuan Truong Nguyen, Daniel Thomas, Brenda Kusler, Alina Garbuzov, John Ramunas, Colin Holbrook, Christopher Y. Park, Helen Blau, Garry P. Nolan, Steven E. Artandi, Beverly S. Mitchell

PLoS One. 2015; 10(7): e0131722. Published online 2015 Jul 2. doi: 10.1371/journal.pone.0131722

PMCID:: PMC4489842

Abstract Article PDF–2.4M

Select item 359772119.

A Novel Telomerase Activator Suppresses Lung Damage in a Murine Model of Idiopathic Pulmonary Fibrosis

Claude Jourdan Le Saux, Philip Davy, Christopher Brampton, Seema S. Ahuja, Steven Fauce, Pooja Shivshankar, Hieu Nguyen, Mahesh Ramaseshan, Robert Tressler, Zhu Pirot, Calvin B. Harley, Richard Allsopp

PLoS One. 2013; 8(3): e58423. Published online 2013 Mar 14. doi: 10.1371/journal.pone.0058423