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Items: 1 to 20 of 58

1.
Induced Trf2 deletion leads to aging vascular phenotype in mice associated with arterial telomere uncapping, senescence signaling, and oxidative stress
R. Garrett Morgan, Ashley E. Walker, Daniel W. Trott, Daniel R. Machin, Grant D. Henson, Kelly D. Reihl, Richard M. Cawthon, Eros L. Denchi, Yu Liu, Samuel I. Bloom, Tam T. Phuong, Russell S. Richardson, Lisa A. Lesniewski, Anthony J. Donato
J Mol Cell Cardiol. Author manuscript; available in PMC 2020 May 12.
Published in final edited form as: J Mol Cell Cardiol. 2019 Feb; 127: 74–82. Published online 2018 Nov 29. doi: 10.1016/j.yjmcc.2018.11.014
PMCID:
PMC7216296
AbstractArticlePDF–1.5M
2.
Stem cell expansion during carcinogenesis in stem cell depleted conditional telomeric repeat factor 2 null mutant mice
Bojana Bojovic, Hoang-Yen Ho, Jianchun Wu, David L. Crowe
Oncogene. Author manuscript; available in PMC 2014 Apr 24.
Published in final edited form as: Oncogene. 2013 Oct 24; 32(43): 5156–5166. Published online 2012 Nov 26. doi: 10.1038/onc.2012.555
PMCID:
PMC3910501
AbstractArticlePDF–1.0M
3.
Genetic dissection of the mechanisms underlying telomere-associated diseases: impact of the TRF2 telomeric protein on mouse epidermal stem cells
Gerdine J. Stout, Maria A. Blasco
Dis Model Mech. 2009 Mar-Apr; 2(3-4): 139–156. Published online 2009 Feb 23. doi: 10.1242/dmm.002121
PMCID:
PMC2650195
AbstractArticle
4.
Hepatocytes with extensive telomere deprotection and fusion remain viable and regenerate liver mass through endoreduplication
Eros Lazzerini Denchi, Giulia Celli, Titia de Lange
Genes Dev. 2006 Oct 1; 20(19): 2648–2653. doi: 10.1101/gad.1453606
Correction in:
Genes Dev. 2021 Nov 1; 35(21-22): 1548–1549.
PMCID:
PMC1578691
AbstractArticlePDF–853K
5.
Different telomere damage signaling pathways in human and mouse cells
Agata Smogorzewska, Titia de Lange
EMBO J. 2002 Aug 15; 21(16): 4338–4348. doi: 10.1093/emboj/cdf433
PMCID:
PMC126171
AbstractArticlePDF–377K
6.
Intact mitochondrial function in the setting of telomere‐induced senescence
Daniel I. Sullivan, Fiona M. Bello, Agustin Gil Silva, Kevin M. Redding, Luca Giordano, Angela M. Hinchie, Kelly E. Loughridge, Ana L. Mora, Melanie Königshoff, Brett A. Kaufman, Michael J. Jurczak, Jonathan K. Alder
Aging Cell. 2023 Oct; 22(10): e13941. Published online 2023 Sep 8. doi: 10.1111/acel.13941
PMCID:
PMC10577573
AbstractArticlePDF–4.8M
7.
TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNA
Parminder Kaur, Ryan Barnes, Hai Pan, Ariana C Detwiler, Ming Liu, Chelsea Mahn, Jonathan Hall, Zach Messenger, Changjiang You, Jacob Piehler, Robert C Smart, Robert Riehn, Patricia L Opresko, Hong Wang
Nucleic Acids Res. 2021 Dec 16; 49(22): 13000–13018. Published online 2021 Dec 9. doi: 10.1093/nar/gkab1142
PMCID:
PMC8682769
AbstractArticlePDF–6.2M
8.
Molecular Consequences of Depression Treatment: A Potential In Vitro Mechanism for Antidepressants-Induced Reprotoxic Side Effects
Przemysław Sołek, Jennifer Mytych, Anna Tabęcka-Łonczyńska, Marek Koziorowski
Int J Mol Sci. 2021 Nov; 22(21): 11855. Published online 2021 Nov 1. doi: 10.3390/ijms222111855
PMCID:
PMC8584852
AbstractArticlePDF–21M
9.
TRF2 Protein Interacts with Core Histones to Stabilize Chromosome Ends
Akimitsu Konishi, Takashi Izumi, Shigeomi Shimizu
J Biol Chem. 2016 Sep 23; 291(39): 20798–20810. Published online 2016 Aug 11. doi: 10.1074/jbc.M116.719021
PMCID:
PMC5034068
AbstractArticlePDF–3.3M
10.
DUB-resistant ubiquitin to survey ubiquitination switches in mammalian cells
Miklós Békés, Keiji Okamoto, Sarah B. Crist, Mathew J. Jones, Jessica R. Chapman, Bradley Brasher, Francesco Melandri, Beatrix Ueberheide, Eros Lazzerini Denchi, Tony T. Huang
Cell Rep. Author manuscript; available in PMC 2014 Jan 13.
Published in final edited form as: Cell Rep. 2013 Nov 14; 5(3): 826–838. Published online 2013 Nov 7. doi: 10.1016/j.celrep.2013.10.008
PMCID:
PMC3889155
AbstractArticlePDF–3.2M
11.
Taf7l cooperates with Trf2 to regulate spermiogenesis
Haiying Zhou, Ivan Grubisic, Ke Zheng, Ying He, P. Jeremy Wang, Tommy Kaplan, Robert Tjian
Proc Natl Acad Sci U S A. 2013 Oct 15; 110(42): 16886–16891. Published online 2013 Sep 30. doi: 10.1073/pnas.1317034110
PMCID:
PMC3801064
AbstractArticlePDF–1.1M
12.
A two-step mechanism for TRF2-mediated chromosome end protection
Keiji Okamoto, Cristina Bartocci, Iliana Ouzounov, Jolene K. Diedrich, John R. Yates, III, Eros Lazzerini Denchi
Nature. Author manuscript; available in PMC 2013 Aug 28.
Published in final edited form as: Nature. 2013 Feb 28; 494(7438): 502–505. Published online 2013 Feb 6. doi: 10.1038/nature11873
PMCID:
PMC3733551
AbstractArticlePDF–757K
13.
Nontelomeric splice variant of telomere repeat-binding factor 2 maintains neuronal traits by sequestering repressor element 1-silencing transcription factor
Peisu Zhang, Rebecca Casaday-Potts, Patricia Precht, Haiyang Jiang, Yie Liu, Michael J. Pazin, Mark P. Mattson
Proc Natl Acad Sci U S A. 2011 Sep 27; 108(39): 16434–16439. Published online 2011 Sep 8. doi: 10.1073/pnas.1106906108
PMCID:
PMC3182730
AbstractArticlePDF–1.3M
14.
PARP1 Is a TRF2-associated Poly(ADP-Ribose)Polymerase and Protects Eroded Telomeres
Marla Gomez, Jun Wu, Valérie Schreiber, John Dunlap, Françoise Dantzer, Yisong Wang, Yie Liu
Mol Biol Cell. 2006 Apr; 17(4): 1686–1696. doi: 10.1091/mbc.E05-07-0672
PMCID:
PMC1415310
AbstractArticlePDF–429K
15.
TRF2-independent chromosome end protection during pluripotency
Phil Ruis, David Van Ly, Valerie Borel, Georgia R. Kafer, Afshan McCarthy, Steven Howell, Robert Blassberg, Ambrosius P. Snijders, James Briscoe, Kathy K. Niakan, Paulina Marzec, Anthony J. Cesare, Simon J. Boulton
Nature. Author manuscript; available in PMC 2023 Mar 23.
Published in final edited form as: Nature. 2021 Jan 7; 589(7840): 103–109. Published online 2020 Nov 25. doi: 10.1038/s41586-020-2960-y
PMCID:
PMC7614352
AbstractArticlePDF–8.2M
16.
Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe
Pol Margalef, Panagiotis Kotsantis, Valerie Borel, Roberto Bellelli, Stephanie Panier, Simon J. Boulton
Cell. 2018 Jan 25; 172(3): 439–453.e14. doi: 10.1016/j.cell.2017.11.047
PMCID:
PMC5786504
AbstractArticlePDF–5.7M
17.
DNA damage response inhibition at dysfunctional telomeres by modulation of telomeric DNA damage response RNAs
Francesca Rossiello, Julio Aguado, Sara Sepe, Fabio Iannelli, Quan Nguyen, Sethuramasundaram Pitchiaya, Piero Carninci, Fabrizio d’Adda di Fagagna
Nat Commun. 2017; 8: 13980. Published online 2017 Feb 27. doi: 10.1038/ncomms13980
Correction in:
Nat Commun. 2017; 8: 15344.
PMCID:
PMC5473644
AbstractArticlePDF–2.5M
18.
Multiple roles for Mre11 at uncapped telomeres
Yibin Deng, Xiaolan Guo, David O. Ferguson, Sandy Chang
Nature. Author manuscript; available in PMC 2010 Feb 15.
Published in final edited form as: Nature. 2009 Aug 13; 460(7257): 914–918. Published online 2009 Jul 26. doi: 10.1038/nature08196
PMCID:
PMC2760383
AbstractArticlePDF–1.5M
19.
Cell cycle control of telomere protection and NHEJ revealed by a ts mutation in the DNA-binding domain of TRF2
Akimitsu Konishi, Titia de Lange
Genes Dev. 2008 May 1; 22(9): 1221–1230. doi: 10.1101/gad.1634008
PMCID:
PMC2335317
AbstractArticlePDF–829K
20.
DNA damage response at telomeres boosts the transcription of SARS‐CoV‐2 receptor ACE2 during aging
Sara Sepe, Francesca Rossiello, Valeria Cancila, Fabio Iannelli, Valentina Matti, Giada Cicio, Matteo Cabrini, Eugenia Marinelli, Busola R Alabi, Alessia di Lillo, Arianna Di Napoli, Jerry W Shay, Claudio Tripodo, Fabrizio d’Adda di Fagagna
EMBO Rep. 2022 Feb 3; 23(2): e53658. Published online 2021 Dec 2. doi: 10.15252/embr.202153658
PMCID:
PMC8811650
AbstractArticlePDF–2.8M

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