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Select item 44949131.

Cripto-1 as a novel therapeutic target for triple negative breast cancer

Nadia P. Castro, Natalie D. Fedorova-Abrams, Anand S. Merchant, Maria Cristina Rangel, Tadahiro Nagaoka, Hideaki Karasawa, Malgorzata Klauzinska, Stephen M. Hewitt, Kajal Biswas, Shyam K. Sharan, David S. Salomon

Oncotarget. 2015 May 20; 6(14): 11910–11929. Published online 2014 May 19. doi: 10.18632/oncotarget.4182

PMCID:: PMC4494913

Abstract Article PDF–2.5M

Select item 16035552.

Overexpression of Human Cripto-1 in Transgenic Mice Delays Mammary Gland Development and Differentiation and Induces Mammary Tumorigenesis

Youping Sun, Luigi Strizzi, Ahmed Raafat, Morihisa Hirota, Caterina Bianco, Lionel Feigenbaum, Nicholas Kenney, Christian Wechselberger, Robert Callahan, David S. Salomon

Am J Pathol. 2005 Aug; 167(2): 585–597. doi: 10.1016/S0002-9440(10)63000-3

PMCID:: PMC1603555

Abstract Article PDF–3.1M

Select item 92927993.

Cripto favors chondrocyte hypertrophy via TGF‐β SMAD1/5 signaling during development of osteoarthritis

Amaya Garcia de Vinuesa, Gonzalo Sanchez‐Duffhues, Esmeralda Blaney‐Davidson, Arjan van Caam, Kirsten Lodder, Yolande Ramos, Margreet Kloppenburg, Ingrid Meulenbelt, Peter van der Kraan, Marie‐José Goumans, Peter ten Dijke

J Pathol. 2021 Nov; 255(3): 330–342. Published online 2021 Sep 6. doi: 10.1002/path.5774

PMCID:: PMC9292799

Abstract Article PDF–20M

Select item 86997994.

Oncofetal Protein CRIPTO Is Involved in Wound Healing and Fibrogenesis in the Regenerating Liver and Is Associated with the Initial Stages of Cardiac Fibrosis

Sofia Karkampouna, Danny van der Helm, Mario Scarpa, Bart van Hoek, Hein W. Verspaget, Marie-Jose Goumans, Minneke J. Coenraad, Boudewijn P.T. Kruithof, Marianna Kruithof-de Julio

Cells. 2021 Dec; 10(12): 3325. Published online 2021 Nov 26. doi: 10.3390/cells10123325

PMCID:: PMC8699799

Abstract Article PDF–6.1M

Select item 84575855.

Liver-specific over-expression of Cripto-1 in transgenic mice promotes hepatocyte proliferation and deregulated expression of hepatocarcinogenesis-related genes and signaling pathways

Yu Liu, Yan-Qing Li, Shi-Hao Huang, Yong-Long Li, Jia-Wei Xia, Jun-Shuang Jia, Fang Wei, Jia-Hong Wang, Guan-Qi Dai, Yu-Cai Wang, Xiao-Yan Li, Liu-Xin Han, Xiao-Ling Zhang, Xu-Dong Xiang, Wen-Tao Zhao, Dong Xiao, Xiao-Lin Lin

Aging (Albany NY) 2021 Sep 15; 13(17): 21155–21190. Published online 2021 Sep 13. doi: 10.18632/aging.203402

PMCID:: PMC8457585

Abstract Article PDF–3.3M

Select item 54231406.

Cripto: Expression, epigenetic regulation and potential diagnostic use in testicular germ cell tumors

Cassy M. Spiller, Ad J.M. Gillis, Guillaume Burnet, Hans Stoop, Peter Koopman, Josephine Bowles, Leendert H.J. Looijenga

Mol Oncol. 2016 Apr; 10(4): 526–537. Published online 2015 Nov 18. doi: 10.1016/j.molonc.2015.11.003

PMCID:: PMC5423140

Abstract Article PDF–2.2M

Select item 46461817.

Characterization of Inhibitors and Monoclonal Antibodies That Modulate the Interaction between Plasmodium falciparum Adhesin PfRh4 with Its Erythrocyte Receptor Complement Receptor 1

Nicholas T. Y. Lim, Markus J. Harder, Alexander T. Kennedy, Clara S. Lin, Christopher Weir, Alan F. Cowman, Melissa J. Call, Christoph Q. Schmidt, Wai-Hong Tham

J Biol Chem. 2015 Oct 16; 290(42): 25307–25321. Published online 2015 Aug 31. doi: 10.1074/jbc.M115.657171

PMCID:: PMC4646181

Abstract Article PDF–2.8M

Select item 42093978.

Activation of a Nodal-independent signaling pathway by Cripto-1 mutants with impaired activation of a Nodal-dependent signaling pathway

Caterina Bianco, Margaret Mysliwiec, Kazuhide Watanabe, Mario Mancino, Tadahiro Nagaoka, Monica Gonzales, David S. Salomon

FEBS Lett. Author manuscript; available in PMC 2014 Oct 27.

Published in final edited form as: FEBS Lett. 2008 Dec 10; 582(29): 3997–4002. Published online 2008 Nov 18. doi: 10.1016/j.febslet.2008.10.052

PMCID:: PMC4209397

Abstract Article PDF–623K

Select item 40791619.

Cripto haploinsufficiency affects in vivo colon tumor development

EMILIA GIORGIO, ANNAMARIA LIGUORO, LUCA D’ORSI, SARA MANCINELLI, ANTONIO BARBIERI, GIUSEPPE PALMA, CLAUDIO ARRA, GIOVANNA L. LIGUORI

Int J Oncol. 2014 Jul; 45(1): 31–40. Published online 2014 Apr 30. doi: 10.3892/ijo.2014.2412

PMCID:: PMC4079161

Abstract Article PDF–1002K

Select item 337891410.

Role of Cripto-1 during Epithelial-to-Mesenchymal Transition in Development and Cancer

Maria C. Rangel, Hideaki Karasawa, Nadia P. Castro, Tadahiro Nagaoka, David S. Salomon, Caterina Bianco

Am J Pathol. 2012 Jun; 180(6): 2188–2200. doi: 10.1016/j.ajpath.2012.02.031

PMCID:: PMC3378914

Abstract Article PDF–2.0M

Select item 316008711.

Regulation of extra-embryonic endoderm stem cell differentiation by Nodal and Cripto signaling

Marianna Kruithof-de Julio, Mariano J. Alvarez, Antonella Galli, Jianhua Chu, Sandy M. Price, Andrea Califano, Michael M. Shen

Development. 2011 Sep 15; 138(18): 3885–3895. doi: 10.1242/dev.065656

PMCID:: PMC3160087

Abstract Article

Select item 277407712.

Cripto-1 Is Required for Hypoxia to Induce Cardiac Differentiation of Mouse Embryonic Stem Cells

Caterina Bianco, Catherine Cotten, Enza Lonardo, Luigi Strizzi, Christina Baraty, Mario Mancino, Monica Gonzales, Kazuhide Watanabe, Tadahiro Nagaoka, Colin Berry, Andrew E. Arai, Gabriella Minchiotti, David S. Salomon

Am J Pathol. 2009 Nov; 175(5): 2146–2158. doi: 10.2353/ajpath.2009.090218

PMCID:: PMC2774077

Abstract Article PDF–1.9M

Select item 217352413.

Nodal-dependent Cripto signaling promotes cardiomyogenesis and redirects the neural fate of embryonic stem cells

Silvia Parisi, Daniela D'Andrea, Carmine T. Lago, Eileen D. Adamson, M. Graziella Persico, Gabriella Minchiotti

J Cell Biol. 2003 Oct 27; 163(2): 303–314. doi: 10.1083/jcb.200303010

PMCID:: PMC2173524

Abstract Article PDF–1.0M

Select item 169852914.

Cripto Binds Transforming Growth Factor β (TGF-β) and Inhibits TGF-β Signaling

Peter C. Gray, Gidi Shani, Kevin Aung, Jonathan Kelber, Wylie Vale

Mol Cell Biol. 2006 Dec; 26(24): 9268–9278. Published online 2006 Oct 9. doi: 10.1128/MCB.01168-06

Correction in:: Mol Cell Biol. 2008 Dec; 28(23): 7260.

PMCID:: PMC1698529

Abstract Article PDF–479K

Select item 40106915.

Molecular characterization of a gene of the 'EGF family' expressed in undifferentiated human NTERA2 teratocarcinoma cells.

A Ciccodicola, R Dono, S Obici, A Simeone, M Zollo, M G Persico

EMBO J. 1989 Jul; 8(7): 1987–1991. doi: 10.1002/j.1460-2075.1989.tb03605.x

PMCID:: PMC401069

Summary Page Browse PDF–915K

Select item 1041925816.

Cripto Is Targeted by miR-1a-3p in a Mouse Model of Heart Development

Tiziana Angrisano, Francesca Varrone, Elvira Ragozzino, Annalisa Fico, Gabriella Minchiotti, Mariarita Brancaccio

Int J Mol Sci. 2023 Aug; 24(15): 12251. Published online 2023 Jul 31. doi: 10.3390/ijms241512251

PMCID:: PMC10419258

Abstract Article PDF–4.4M

Select item 1025951617.

A Mesp1-dependent developmental breakpoint in transcriptional and epigenomic specification of early cardiac precursors

Alexis Leigh Krup, Sarah A. B. Winchester, Sanjeev S. Ranade, Ayushi Agrawal, W. Patrick Devine, Tanvi Sinha, Krishna Choudhary, Martin H. Dominguez, Reuben Thomas, Brian L. Black, Deepak Srivastava, Benoit G. Bruneau

Development. 2023 May 1; 150(9): dev201229. Published online 2023 May 2. doi: 10.1242/dev.201229

PMCID:: PMC10259516

Abstract Article

Select item 463017118.

Cripto-1 Ablation Disrupts Alveolar Development in the Mouse Mammary Gland through a Progesterone Receptor–Mediated Pathway

Malgorzata Klauzinska, David McCurdy, Maria Cristina Rangel, Arun Vaidyanath, Nadia P. Castro, Michael M. Shen, Monica Gonzales, Daniel Bertolette, Caterina Bianco, Robert Callahan, David S. Salomon, Ahmed Raafat

Am J Pathol. 2015 Nov; 185(11): 2907–2922. doi: 10.1016/j.ajpath.2015.07.023

PMCID:: PMC4630171

Abstract Article PDF–2.9M

Select item 351114419.

Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin

Ombretta Guardiola, Peggy Lafuste, Silvia Brunelli, Salvatore Iaconis, Thierry Touvier, Philippos Mourikis, Katrien De Bock, Enza Lonardo, Gennaro Andolfi, Ann Bouché, Giovanna L. Liguori, Michael M. Shen, Shahragim Tajbakhsh, Giulio Cossu, Peter Carmeliet, Gabriella Minchiotti

Proc Natl Acad Sci U S A. 2012 Nov 20; 109(47): E3231–E3240. Published online 2012 Nov 5. doi: 10.1073/pnas.1204017109