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Select item 109175091.

Natural variation in the zinc-finger-encoding exon of Prdm9 affects hybrid sterility phenotypes in mice

Khawla F N AbuAlia, Elena Damm, Kristian K Ullrich, Amisa Mukaj, Emil Parvanov, Jiri Forejt, Linda Odenthal-Hesse

Genetics. 2024 Mar; 226(3): iyae004. Published online 2024 Jan 13. doi: 10.1093/genetics/iyae004

PMCID:: PMC10917509

Abstract Article PDF–2.1M

Select item 94343062.

Genic and chromosomal components of Prdm9-driven hybrid male sterility in mice (Mus musculus)

Barbora Valiskova, Sona Gregorova, Diana Lustyk, Petr Šimeček, Petr Jansa, Jiří Forejt

Genetics. 2022 Sep; 222(1): iyac116. Published online 2022 Aug 4. doi: 10.1093/genetics/iyac116

PMCID:: PMC9434306

Abstract Article PDF–1.4M

Select item 86645813.

Differential effects of two catalytic mutations on full-length PRDM9 and its isolated PR/SET domain reveal a case of pseudomodularity

Natalie R. Powers, Timothy Billings, Kenneth Paigen, Petko M. Petkov

Genetics. 2021 Dec; 219(4): iyab172. Published online 2021 Oct 9. doi: 10.1093/genetics/iyab172

PMCID:: PMC8664581

Abstract Article PDF–1.0M

Select item 86626094.

Altering the Binding Properties of PRDM9 Partially Restores Fertility across the Species Boundary

Benjamin Davies, Anjali Gupta Hinch, Alberto Cebrian-Serrano, Samy Alghadban, Philipp W Becker, Daniel Biggs, Polinka Hernandez-Pliego, Chris Preece, Daniela Moralli, Gang Zhang, Simon Myers, Peter Donnelly

Mol Biol Evol. 2021 Dec; 38(12): 5555–5562. Published online 2021 Sep 7. doi: 10.1093/molbev/msab269

PMCID:: PMC8662609

Abstract Article PDF–480K

Select item 77436435.

Prdm9 Intersubspecific Interactions in Hybrid Male Sterility of House Mouse

Amisa Mukaj, Jaroslav Piálek, Vladana Fotopulosova, Andrew Parker Morgan, Linda Odenthal-Hesse, Emil D Parvanov, Jiri Forejt

Mol Biol Evol. 2020 Dec; 37(12): 3423–3438. Published online 2020 Jul 8. doi: 10.1093/molbev/msaa167

PMCID:: PMC7743643

Abstract Article PDF–1.4M

Select item 70543346.

Refined spatial temporal epigenomic profiling reveals intrinsic connection between PRDM9-mediated H3K4me3 and the fate of double-stranded breaks

Yao Chen, Ruitu Lyu, Bowen Rong, Yuxuan Zheng, Zhen Lin, Ruofei Dai, Xi Zhang, Nannan Xie, Siqing Wang, Fuchou Tang, Fei Lan, Ming-Han Tong

Cell Res. 2020 Mar; 30(3): 256–268. Published online 2020 Feb 11. doi: 10.1038/s41422-020-0281-1

PMCID:: PMC7054334

Abstract Article PDF–3.6M

Select item 67157347.

A high-resolution map of non-crossover events reveals impacts of genetic diversity on mammalian meiotic recombination

Ran Li, Emmanuelle Bitoun, Nicolas Altemose, Robert W. Davies, Benjamin Davies, Simon R. Myers

Nat Commun. 2019; 10: 3900. Published online 2019 Aug 29. doi: 10.1038/s41467-019-11675-y

PMCID:: PMC6715734

Abstract Article PDF–1.5M

Select item 66577318.

PRDM9 Diversity at Fine Geographical Scale Reveals Contrasting Evolutionary Patterns and Functional Constraints in Natural Populations of House Mice

Covadonga Vara, Laia Capilla, Luca Ferretti, Alice Ledda, Rosa A Sánchez-Guillén, Sofia I Gabriel, Guillermo Albert-Lizandra, Beatriu Florit-Sabater, Judith Bello-Rodríguez, Jacint Ventura, Jeremy B Searle, Maria L Mathias, Aurora Ruiz-Herrera

Mol Biol Evol. 2019 Aug; 36(8): 1686–1700. Published online 2019 Apr 19. doi: 10.1093/molbev/msz091

PMCID:: PMC6657731

Abstract Article PDF–1.2M

Select item 66430469.

PRDM9 forms a trimer by interactions within the zinc finger array

Theresa Schwarz, Yasmin Striedner, Andreas Horner, Karin Haase, Jasmin Kemptner, Nicole Zeppezauer, Philipp Hermann, Irene Tiemann-Boege

Life Sci Alliance. 2019 Aug; 2(4): e201800291. Published online 2019 Jul 15. doi: 10.26508/lsa.201800291

PMCID:: PMC6643046

Abstract Article PDF–1.6M

Select item 663326410.

Histone methyltransferase PRDM9 is not essential for meiosis in male mice

Ondrej Mihola, Florencia Pratto, Kevin Brick, Eliska Linhartova, Tatyana Kobets, Petr Flachs, Christopher L. Baker, Radislav Sedlacek, Kenneth Paigen, Petko M. Petkov, R. Daniel Camerini-Otero, Zdenek Trachtulec

Genome Res. 2019 Jul; 29(7): 1078–1086. doi: 10.1101/gr.244426.118

PMCID:: PMC6633264

Abstract Article PDF–8.3M

Select item 632487511.

Cisplatin-induced DNA double-strand breaks promote meiotic chromosome synapsis in PRDM9-controlled mouse hybrid sterility

Liu Wang, Barbora Valiskova, Jiri Forejt

eLife. 2018; 7: e42511. Published online 2018 Dec 28. doi: 10.7554/eLife.42511

PMCID:: PMC6324875

Abstract Article PDF–3.1M

Select item 590216112.

Modulation of Prdm9-controlled meiotic chromosome asynapsis overrides hybrid sterility in mice

Sona Gregorova, Vaclav Gergelits, Irena Chvatalova, Tanmoy Bhattacharyya, Barbora Valiskova, Vladana Fotopulosova, Petr Jansa, Diana Wiatrowska, Jiri Forejt

eLife. 2018; 7: e34282. Published online 2018 Mar 14. doi: 10.7554/eLife.34282

PMCID:: PMC5902161

Abstract Article PDF–3.2M

Select item 568821813.

The PRDM9 KRAB domain is required for meiosis and involved in protein interactions

Yukiko Imai, Frédéric Baudat, Miguel Taillepierre, Marcello Stanzione, Attila Toth, Bernard de Massy

Chromosoma. 2017; 126(6): 681–695. Published online 2017 May 19. doi: 10.1007/s00412-017-0631-z

PMCID:: PMC5688218

Abstract Article PDF–1.9M

Select item 484159214.

Hybrid Sterility Locus on Chromosome X Controls Meiotic Recombination Rate in Mouse

Maria Balcova, Barbora Faltusova, Vaclav Gergelits, Tanmoy Bhattacharyya, Ondrej Mihola, Zdenek Trachtulec, Corinna Knopf, Vladana Fotopulosova, Irena Chvatalova, Sona Gregorova, Jiri Forejt

PLoS Genet. 2016 Apr; 12(4): e1005906. Published online 2016 Apr 22. doi: 10.1371/journal.pgen.1005906