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Select item 101697301.

Oxygen availability influences the incidence of testicular teratoma in Dnd1Ter/+ mice

Ximena M. Bustamante-Marin, Blanche Capel

Front Genet. 2023; 14: 1179256. Published online 2023 Apr 26. doi: 10.3389/fgene.2023.1179256

PMCID:: PMC10169730

Abstract Article PDF–2.6M

Select item 101158112.

Loss of Dead end1 induces testicular teratomas from primordial germ cells that failed to undergo sexual differentiation in embryonic testes

Atsuki Imai, Kazuya Matsuda, Yuki Niimi, Atsushi Suzuki

Sci Rep. 2023; 13: 6398. Published online 2023 Apr 19. doi: 10.1038/s41598-023-33706-x

PMCID:: PMC10115811

Abstract Article PDF–4.3M

Select item 68033763.

The RNA-binding protein DND1 acts sequentially as a negative regulator of pluripotency and a positive regulator of epigenetic modifiers required for germ cell reprogramming

Victor A. Ruthig, Matthew B. Friedersdorf, Jason A. Garness, Steve C. Munger, Corey Bunce, Jack D. Keene, Blanche Capel

Development. 2019 Oct 1; 146(19): dev175950. Published online 2019 Jul 25. doi: 10.1242/dev.175950

PMCID:: PMC6803376

Abstract Article

Select item 58295154.

Dnd1-mediated epigenetic control of teratoma formation in mouse

Wei Gu, Kentaro Mochizuki, Kei Otsuka, Ryohei Hamada, Asuka Takehara, Yasuhisa Matsui

Biol Open. 2018 Jan 15; 7(1): bio032318. Published online 2018 Jan 15. doi: 10.1242/bio.032318

PMCID:: PMC5829515

Abstract Article PDF–2.1M

Select item 26477415.

Chromosome X modulates incidence of testicular germ cell tumors in Ter mice

Shirley Hammond, Rui Zhu, Angabin Matin, Kirsten K. Youngren, Josephine Lam, Philip Anderson

Mamm Genome. Author manuscript; available in PMC 2009 Feb 25.

Published in final edited form as: Mamm Genome. 2007 Dec; 18(12): 832–838. Published online 2007 Nov 30. doi: 10.1007/s00335-007-9075-8

PMCID:: PMC2647741

Abstract Article PDF–1.0M

Select item 25183186.

The Role of dead-end in Germ-cell Tumor Development

RUI ZHU, CHITRALEKHA BHATTACHARYA, ANGABIN MATIN

Ann N Y Acad Sci. Author manuscript; available in PMC 2008 Aug 20.

Published in final edited form as: Ann N Y Acad Sci. 2007 Dec; 1120: 181–186. Published online 2007 Sep 28. doi: 10.1196/annals.1411.006

PMCID:: PMC2518318

Abstract Article PDF–183K

Select item 10639697.

Spontaneous Testicular Teratomas in an Inbred Strain of Mice

Leroy C. Stevens, Jr., C. C. Little

Proc Natl Acad Sci U S A. 1954 Nov; 40(11): 1080–1087. doi: 10.1073/pnas.40.11.1080

PMCID:: PMC1063969

Summary Page Browse PDF–1.7M

Select item 78760328.

MC4R mutant mice develop ovarian teratomas

Abdullah An Naser, Takehiro Miyazaki, Jun Wang, Shuji Takabayashi, Theeranukul Pachoensuk, Toshinobu Tokumoto

Sci Rep. 2021; 11: 3483. Published online 2021 Feb 10. doi: 10.1038/s41598-021-83001-w

PMCID:: PMC7876032

Abstract Article PDF–4.8M

Select item 36939589.

Contrasting effects of Deadend1 (Dnd1) gain and loss of function mutations on allelic inheritance, testicular cancer, and intestinal polyposis

Jennifer L Zechel, Stephanie K Doerner, Angela Lager, Paul J Tesar, Jason D Heaney, Joseph H Nadeau

BMC Genet. 2013; 14: 54. Published online 2013 Jun 17. doi: 10.1186/1471-2156-14-54

PMCID:: PMC3693958

Abstract Article PDF–666K

Select item 347864810.

Transgenerational epigenetic effects of the Apobec1 cytidine deaminase deficiency on testicular germ cell tumor susceptibility and embryonic viability

Vicki R. Nelson, Jason D. Heaney, Paul J. Tesar, Nicholas O. Davidson, Joseph H. Nadeau

Proc Natl Acad Sci U S A. 2012 Oct 9; 109(41): E2766–E2773. Published online 2012 Aug 24. doi: 10.1073/pnas.1207169109

PMCID:: PMC3478648

Abstract Article PDF–818K

Select item 251804011.

What leads from dead-end?

A. Matin

Cell Mol Life Sci. 2007 Jun; 64(11): 1317–1322. Published online 2007 Apr 25. doi: 10.1007/s00018-007-6433-3

PMCID:: PMC2518040

Abstract Article PDF–304K

Select item 185514612.

The mouse dead-end gene isoform α is necessary for germ cell and embryonic viability

Chitralekha Bhattacharya, Sita Aggarwal, Rui Zhu, Madhu Kumar, Ming Zhao, Marvin L. Meistrich, Angabin Matin

Biochem Biophys Res Commun. Author manuscript; available in PMC 2007 Apr 24.

Published in final edited form as: Biochem Biophys Res Commun. 2007 Mar 30; 355(1): 194–199. Published online 2007 Feb 2. doi: 10.1016/j.bbrc.2007.01.138

PMCID:: PMC1855146

Abstract Article PDF–895K

Select item 1015134313.

The Mc4r gene is responsible for the development of experimentally induced testicular teratomas

Syunsuke Seki, Kaoru Ohura, Takehiro Miyazaki, Abdullah An Naser, Shuji Takabayashi, Eisei Tsutsumi, Toshinobu Tokumoto

Sci Rep. 2023; 13: 6756. Published online 2023 May 1. doi: 10.1038/s41598-023-32784-1

PMCID:: PMC10151343

Abstract Article PDF–2.2M

Select item 1001056214.

The RNA binding protein DND1 is elevated in a subpopulation of pro-spermatogonia and targets chromatin modifiers and translational machinery during late gestation

Victor A. Ruthig, Talia Hatkevich, Josiah Hardy, Matthew B. Friedersdorf, Chloé Mayère, Serge Nef, Jack D. Keene, Blanche Capel

PLoS Genet. 2023 Mar; 19(3): e1010656. Published online 2023 Mar 1. doi: 10.1371/journal.pgen.1010656

PMCID:: PMC10010562

Abstract Article PDF–2.8M

Select item 860408115.

Cdc42 activity in Sertoli cells is essential for maintenance of spermatogenesis

Anna Heinrich, Bidur Bhandary, Sarah J. Potter, Nancy Ratner, Tony DeFalco

Cell Rep. Author manuscript; available in PMC 2021 Nov 19.

Published in final edited form as: Cell Rep. 2021 Oct 26; 37(4): 109885. doi: 10.1016/j.celrep.2021.109885

PMCID:: PMC8604081

Abstract Article PDF–2.2M

Select item 632244816.

Left-Biased Spermatogenic Failure in 129/SvJ Dnd1^Ter/+ Mice Correlates with Differences in Vascular Architecture, Oxygen Availability, and Metabolites

Ximena M. Bustamante-Marin, Matthew S. Cook, Jessica Gooding, Christopher Newgard, Blanche Capel

Biol Reprod. 2015 Sep; 93(3): 78, 1-13. doi: 10.1095/biolreprod.115.128850

PMCID:: PMC6322448

Abstract Article PDF–2.6M

Select item 548872917.

DND1 maintains germline stem cells via recruitment of the CCR4-NOT complex to target mRNAs

Masashi Yamaji, Miki Jishage, Cindy Meyer, Hemant Suryawanshi, Evan Der, Misaki Yamaji, Aitor Garzia, Pavel Morozov, Sudhir Manickavel, Hannah L. McFarland, Robert G. Roeder, Markus Hafner, Thomas Tuschl

Nature. Author manuscript; available in PMC 2017 Sep 15.

Published in final edited form as: Nature. 2017 Mar 23; 543(7646): 568–572. Published online 2017 Mar 15. doi: 10.1038/nature21690

PMCID:: PMC5488729

Abstract Article PDF–2.4M

Select item 337504818.

The Role of the Mouse Y Chromosome on Susceptibility to Testicular Germ Cell Tumors

Philip D. Anderson, Man-Yee Lam, Christophe Poirier, Colin E. Bishop, Joseph H. Nadeau

Cancer Res. Author manuscript; available in PMC 2012 Jun 14.

Published in final edited form as: Cancer Res. 2009 Apr 15; 69(8): 3614–3618. Published online 2009 Apr 7. doi: 10.1158/0008-5472.CAN-08-4881

PMCID:: PMC3375048

Abstract Article PDF–615K

Select item 718569319.

Mouse dead end1 acts with Nanos2 and Nanos3 to regulate testicular teratoma incidence

Atsuki Imai, Yoshihiko Hagiwara, Yuki Niimi, Toshinobu Tokumoto, Yumiko Saga, Atsushi Suzuki

PLoS One. 2020; 15(4): e0232047. Published online 2020 Apr 27. doi: 10.1371/journal.pone.0232047

PMCID:: PMC7185693

Abstract Article PDF–3.0M

Select item 569523720.

Chemotherapy-Induced Depletion of OCT4-Positive Cancer Stem Cells in a Mouse Model of Malignant Testicular Cancer

Timothy M. Pierpont, Amy M. Lyndaker, Claire M. Anderson, Qiming Jin, Elizabeth S. Moore, Jamie L. Roden, Alicia Braxton, Lina Bagepalli, Nandita Kataria, Hilary Zhaoxu Hu, Jason Garness, Matthew S. Cook, Blanche Capel, Donald H. Schlafer, Teresa Southard, Robert S. Weiss

Cell Rep. Author manuscript; available in PMC 2017 Nov 20.

Published in final edited form as: Cell Rep. 2017 Nov 14; 21(7): 1896–1909. doi: 10.1016/j.celrep.2017.10.078