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Items: 1 to 20 of 52

1.
Involution of brown adipose tissue through a Syntaxin 4 dependent pyroptosis pathway
Xiaofan Yu, Gabrielle Benitez, Peter Tszki Wei, Sofia V. Krylova, Ziyi Song, Li Liu, Meifan Zhang, Alus M. Xiaoli, Henna Wei, Fenfen Chen, Simone Sidoli, Fajun Yang, Kosaku Shinoda, Jeffrey E. Pessin, Daorong Feng
Nat Commun. 2024; 15: 2856. Published online 2024 Apr 2. doi: 10.1038/s41467-024-46944-y
PMCID:
PMC10987578
AbstractArticlePDF–4.7M
2.
Syntaxin 4 Enrichment in β-Cells Prevents Conversion to Autoimmune Diabetes in Non-Obese Diabetic (NOD) Mice
Eunjin Oh, Erika M. McCown, Miwon Ahn, Pablo A. Garcia, Sergio Branciamore, Shanshan Tang, De-Fu Zeng, Bart O. Roep, Debbie C. Thurmond
Diabetes. 2021 Dec; 70(12): 2837–2849. Published online 2021 Sep 23. doi: 10.2337/db21-0170
PMCID:
PMC8660989
AbstractArticlePDF–4.0M
3.
Syntaxin 4 Expression in Pancreatic β-Cells Promotes Islet Function and Protects Functional β-Cell Mass
Eunjin Oh, Miwon Ahn, Solomon Afelik, Thomas C. Becker, Bart O. Roep, Debbie C. Thurmond
Diabetes. 2018 Dec; 67(12): 2626–2639. Published online 2018 Oct 10. doi: 10.2337/db18-0259
PMCID:
PMC6245223
AbstractArticlePDF–2.8M
4.
Membrane translocation of t-SNARE protein syntaxin-4 abrogates ground-state pluripotency in mouse embryonic stem cells
Natsumi Hagiwara-Chatani, Kota Shirai, Takumi Kido, Tomoatsu Horigome, Akihiro Yasue, Naoki Adachi, Yohei Hirai
Sci Rep. 2017; 7: 39868. Published online 2017 Jan 6. doi: 10.1038/srep39868
PMCID:
PMC5216394
AbstractArticlePDF–2.8M
5.
Potential Site Effects and Transgene Expression Discrepancies in Mouse Lifespan Studies
Debbie C. Thurmond, Eunjin Oh, Richard A. Miller
Cell Metab. Author manuscript; available in PMC 2016 Feb 26.
Published in final edited form as: Cell Metab. 2015 Sep 1; 22(3): 346–347. doi: 10.1016/j.cmet.2015.07.024
PMCID:
PMC4768787
ArticlePDF–143K
6.
Syntaxin 4 Overexpression Ameliorates Effects of Aging and High Fat Diet on Glucose Control and Extends Lifespan
Eunjin Oh, Richard A. Miller, Debbie C. Thurmond
Cell Metab. Author manuscript; available in PMC 2016 Sep 1.
Published in final edited form as: Cell Metab. 2015 Sep 1; 22(3): 499–507. doi: 10.1016/j.cmet.2015.07.023
PMCID:
PMC4560841
AbstractArticlePDF–867K
7.
Filamentous Actin Regulates Insulin Exocytosis through Direct Interaction with Syntaxin 4
Jenna L. Jewell, Wei Luo, Eunjin Oh, Zhanxiang Wang, Debbie C. Thurmond
J Biol Chem. 2008 Apr 18; 283(16): 10716–10726. doi: 10.1074/jbc.M709876200
PMCID:
PMC2376824
AbstractArticlePDF–993K
8.
Syntaxin 4 heterozygous knockout mice develop muscle insulin resistance
Chunmei Yang, Kenneth J. Coker, Jason K. Kim, Silvia Mora, Debbie C. Thurmond, Ann C. Davis, Baoli Yang, Roger A. Williamson, Gerald I. Shulman, Jeffrey E. Pessin
J Clin Invest. 2001 May 15; 107(10): 1311–1318. doi: 10.1172/JCI12274
PMCID:
PMC209300
AbstractArticlePDF–838K
9.
Enrichment of the exocytosis protein STX4 in skeletal muscle remediates peripheral insulin resistance and alters mitochondrial dynamics via Drp1
Karla E. Merz, Jinhee Hwang, Chunxue Zhou, Rajakrishnan Veluthakal, Erika M. McCown, Angelica Hamilton, Eunjin Oh, Wenting Dai, Patrick T. Fueger, Lei Jiang, Janice. M. Huss, Debbie C. Thurmond
Nat Commun. 2022; 13: 424. Published online 2022 Jan 20. doi: 10.1038/s41467-022-28061-w
PMCID:
PMC8776765
AbstractArticlePDF–1.9M
10.
Knockout of syntaxin-4 in 3T3-L1 adipocytes reveals new insight into GLUT4 trafficking and adiponectin secretion
Hannah L. Black, Rachel Livingstone, Cynthia C. Mastick, Mohammed Al Tobi, Holly Taylor, Angéline Geiser, Laura Stirrat, Dimitrios Kioumourtzoglou, John R. Petrie, James G. Boyle, Nia J. Bryant, Gwyn W. Gould
J Cell Sci. 2022 Jan 1; 135(1): jcs258375. Published online 2022 Jan 10. doi: 10.1242/jcs.258375
PMCID:
PMC8767277
AbstractArticle
11.
Gelsolin Associates with the N Terminus of Syntaxin 4 to Regulate Insulin Granule Exocytosis
Michael A. Kalwat, Dean A. Wiseman, Wei Luo, Zhanxiang Wang, Debbie C. Thurmond
Mol Endocrinol. 2012 Jan; 26(1): 128–141. Published online 2011 Nov 22. doi: 10.1210/me.2011-1112
PMCID:
PMC3248323
AbstractArticle
12.
Stimulus-induced S-Nitrosylation of Syntaxin 4 Impacts Insulin Granule Exocytosis
Dean A. Wiseman, Michael A. Kalwat, Debbie C. Thurmond
J Biol Chem. 2011 May 6; 286(18): 16344–16354. Published online 2011 Mar 10. doi: 10.1074/jbc.M110.214031
PMCID:
PMC3091240
AbstractArticlePDF–2.0M
13.
Mammalian Homolog of Drosophila Tumor Suppressor Lethal (2) Giant Larvae Interacts with Basolateral Exocytic Machinery in Madin-Darby Canine Kidney Cells
Anne Muō̈sch, David Cohen, Charles Yeaman, W. James Nelson, Enrique Rodriguez-Boulan, Patrick J. Brennwald
Mol Biol Cell. 2002 Jan; 13(1): 158–168. doi: 10.1091/mbc.01-10-0496
PMCID:
PMC65098
AbstractArticlePDF–1.0M
14.
Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion
Shaojing Ye, Zubair A. Karim, Rania Al Hawas, Jeffery E. Pessin, Alexandra H. Filipovich, Sidney W. Whiteheart
Blood. 2012 Sep 20; 120(12): 2484–2492. Prepublished online 2012 Jul 5. doi: 10.1182/blood-2012-05-430603
PMCID:
PMC3448260
AbstractArticle
15.
The Tyrosine Phosphorylation of Munc18c Induces a Switch in Binding Specificity from Syntaxin 4 to Doc2β
Jenna L. Jewell, Eunjin Oh, Sara M. Bennett, Samy O. Meroueh, Debbie C. Thurmond
J Biol Chem. 2008 Aug 1; 283(31): 21734–21746. doi: 10.1074/jbc.M710445200
PMCID:
PMC2490795
AbstractArticlePDF–1.6M
16.
Phosphorylation of Syntaxin 4 by the Insulin Receptor Drives Exocytic SNARE Complex Formation to Deliver GLUT4 to the Cell Surface
Dimitrios Kioumourtzoglou, Hannah L. Black, Mohammed Al Tobi, Rachel Livingstone, John R. Petrie, James G. Boyle, Gwyn W. Gould, Nia J. Bryant
Biomolecules. 2023 Dec; 13(12): 1738. Published online 2023 Dec 2. doi: 10.3390/biom13121738
PMCID:
PMC10741561
AbstractArticlePDF–4.3M
17.
Syntaxin 3, but not syntaxin 4, is required for mast cell–regulated exocytosis, where it plays a primary role mediating compound exocytosis
Elizabeth Sanchez, Erika A. Gonzalez, David S. Moreno, Rodolfo A. Cardenas, Marco A. Ramos, Alfredo J. Davalos, John Manllo, Alejandro I. Rodarte, Youlia Petrova, Daniel C. Moreira, Miguel A. Chavez, Alejandro Tortoriello, Adolfo Lara, Berenice A. Gutierrez, Alan R. Burns, Ruth Heidelberger, Roberto Adachi
J Biol Chem. 2019 Mar 1; 294(9): 3012–3023. Published online 2018 Dec 18. doi: 10.1074/jbc.RA118.005532
PMCID:
PMC6398129
AbstractArticlePDF–2.4M
18.
Nitric Oxide Generated by Tumor-Associated Macrophages Is Responsible for Cancer Resistance to Cisplatin and Correlated With Syntaxin 4 and Acid Sphingomyelinase Inhibition
Cristiana Perrotta, Davide Cervia, Ilaria Di Renzo, Claudia Moscheni, Maria Teresa Bassi, Lara Campana, Cristina Martelli, Elisabetta Catalani, Matteo Giovarelli, Silvia Zecchini, Marco Coazzoli, Annalisa Capobianco, Luisa Ottobrini, Giovanni Lucignani, Patrizia Rosa, Patrizia Rovere-Querini, Clara De Palma, Emilio Clementi
Front Immunol. 2018; 9: 1186. Published online 2018 May 29. doi: 10.3389/fimmu.2018.01186
PMCID:
PMC5987706
AbstractArticlePDF–12M
19.
Munc18c Depletion Selectively Impairs the Sustained Phase of Insulin Release
Eunjin Oh, Debbie C. Thurmond
Diabetes. 2009 May; 58(5): 1165–1174. Published online 2009 Feb 2. doi: 10.2337/db08-1059
Correction in:
Diabetes. 2010 Mar; 59(3): 756.
PMCID:
PMC2671048
AbstractArticlePDF–958K
20.
DOC2B: A Novel Syntaxin-4 Binding Protein Mediating Insulin-Regulated GLUT4 Vesicle Fusion in Adipocytes
Naofumi Fukuda, Masahiro Emoto, Yoshitaka Nakamori, Akihiko Taguchi, Sachiko Miyamoto, Shinsuke Uraki, Yoshitomo Oka, Yukio Tanizawa
Diabetes. 2009 Feb; 58(2): 377–384. doi: 10.2337/db08-0303
PMCID:
PMC2628611
AbstractArticlePDF–722K

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