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Items: 1 to 20 of 34

1.
Unleashing a novel function of Endonuclease G in mitochondrial genome instability
Sumedha Dahal, Humaira Siddiqua, Shivangi Sharma, Ravi K Babu, Diksha Rathore, Sheetal Sharma, Sathees C Raghavan
eLife. 2022; 11: e69916. Published online 2022 Nov 17. doi: 10.7554/eLife.69916
PMCID:
PMC9711528
AbstractArticlePDF–6.0M
2.
Autophagy restricts mitochondrial DNA damage-induced release of ENDOG (endonuclease G) to regulate genome stability
Tung Chao, Hsueh-Tzu Shih, Shih-Chin Hsu, Pei-Jer Chen, Yu-Shan Fan, Yung-Ming Jeng, Zhao-Qing Shen, Ting-Fen Tsai, Zee-Fen Chang
Autophagy. 2021; 17(11): 3444–3460. Published online 2021 Jan 19. doi: 10.1080/15548627.2021.1874209
PMCID:
PMC8632313
AbstractArticlePDF–16M
3.
Endonuclease G promotes mitochondrial genome cleavage and replication
Rahel Stefanie Wiehe, Boris Gole, Laurent Chatre, Paul Walther, Enrico Calzia, Miria Ricchetti, Lisa Wiesmüller
Oncotarget. 2018 Apr 6; 9(26): 18309–18326. Published online 2018 Apr 6. doi: 10.18632/oncotarget.24822
Correction in:
Oncotarget. 2018 Jun 12; 9(45): 27908.
PMCID:
PMC5915074
AbstractArticlePDF–5.3M
4.
Novel Cytoprotective Inhibitors for Apoptotic Endonuclease G
Dae Song Jang, Narsimha R. Penthala, Eugene O. Apostolov, Xiaoying Wang, Peter A. Crooks, Alexei G. Basnakian
DNA Cell Biol. 2015 Feb 1; 34(2): 92–100. doi: 10.1089/dna.2014.2530
PMCID:
PMC4308826
AbstractArticlePDF–581K
5.
Mutagenesis identifies the critical amino acid residues of human endonuclease G involved in catalysis, magnesium coordination, and substrate specificity
Shih-Lu Wu, Chia-Cheng Li, Jaw-Chyun Chen, Yi-Jin Chen, Ching-Ting Lin, Tin-Yun Ho, Chien-Yun Hsiang
J Biomed Sci. 2009; 16(1): 6. Published online 2009 Jan 15. doi: 10.1186/1423-0127-16-6
PMCID:
PMC2653514
AbstractArticlePDF–802K
6.
Endonuclease G promotes cell death of non-invasive human breast cancer cells
Alexei G. Basnakian, Eugene O. Apostolov, Xiaoyan Yin, Stanley O. Abiri, Anna G. Stewart, Amar B. Singh, Sudhir V. Shah
Exp Cell Res. Author manuscript; available in PMC 2007 Dec 10.
Published in final edited form as: Exp Cell Res. 2006 Dec 10; 312(20): 4139–4149. Published online 2006 Sep 20. doi: 10.1016/j.yexcr.2006.09.012
PMCID:
PMC1839947
AbstractArticlePDF–990K
7.
Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modified DNA creating a substrate for recombination
Adam B. Robertson, Julia Robertson, Markus Fusser, Arne Klungland
Nucleic Acids Res. 2014 Dec 1; 42(21): 13280–13293. Published online 2014 Oct 29. doi: 10.1093/nar/gku1032
PMCID:
PMC4245937
AbstractArticlePDF–546K
8.
Endonuclease G mediates α-synuclein cytotoxicity during Parkinson’s disease
Sabrina Büttner, Lukas Habernig, Filomena Broeskamp, Doris Ruli, F Nora Vögtle, Manolis Vlachos, Francesca Macchi, Victoria Küttner, Didac Carmona-Gutierrez, Tobias Eisenberg, Julia Ring, Maria Markaki, Asli Aras Taskin, Stefan Benke, Christoph Ruckenstuhl, Ralf Braun, Chris Van den Haute, Tine Bammens, Anke van der Perren, Kai-Uwe Fröhlich, Joris Winderickx, Guido Kroemer, Veerle Baekelandt, Nektarios Tavernarakis, Gabor G Kovacs, Jörn Dengjel, Chris Meisinger, Stephan J Sigrist, Frank Madeo
EMBO J. 2013 Nov 27; 32(23): 3041–3054. Published online 2013 Oct 15. doi: 10.1038/emboj.2013.228
PMCID:
PMC3844953
AbstractArticlePDF–2.2M
9.
Mitochondrial Nucleases ENDOG and EXOG Participate in Mitochondrial DNA Depletion Initiated by Herpes Simplex Virus 1 UL12.5
Brett A. Duguay, James R. Smiley
J Virol. 2013 Nov; 87(21): 11787–11797. doi: 10.1128/JVI.02306-13
PMCID:
PMC3807374
AbstractArticlePDF–3.2M
10.
Apoptotic death of striatal neurons induced by HIV-1 Tat and gp120: differential involvement of caspase-3 and endonuclease G
Indrapal N. Singh, Robin J. Goody, Celeste Dean, Nael M. Ahmad, Sarah E. Lutz, Pamela E. Knapp, Avindra Nath, Kurt F. Hauser
J Neurovirol. Author manuscript; available in PMC 2015 Jan 28.
Published in final edited form as: J Neurovirol. 2004 Jun; 10(3): 141–151. doi: 10.1080/13550280490441103
PMCID:
PMC4309288
AbstractArticlePDF–3.1M
11.
CHIP has a protective role against oxidative stress-induced cell death through specific regulation of Endonuclease G
J S Lee, T W Seo, J H Yi, K S Shin, S J Yoo
Cell Death Dis. 2013 Jun; 4(6): e666. Published online 2013 Jun 13. doi: 10.1038/cddis.2013.181
PMCID:
PMC3698548
AbstractArticlePDF–3.2M
12.
Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response
Wenjun Wang, Jianshuang Li, Junyang Tan, Miaomiao Wang, Jing Yang, Zhi-Min Zhang, Chuanzhou Li, Alexei G. Basnakian, Hong-Wen Tang, Norbert Perrimon, Qinghua Zhou
Nat Commun. 2021; 12: 476. Published online 2021 Jan 20. doi: 10.1038/s41467-020-20780-2
PMCID:
PMC7817833
AbstractArticlePDF–6.3M
13.
The Proapoptotic Protein BNIP3 Interacts with VDAC to Induce Mitochondrial Release of Endonuclease G
Xiaosha Zhang, Xiuwu Bian, Jiming Kong
PLoS One. 2014; 9(12): e113642. Published online 2014 Dec 1. doi: 10.1371/journal.pone.0113642
PMCID:
PMC4249980
AbstractArticlePDF–4.6M
14.
Ethyl Gallate Induces Apoptosis of HL-60 Cells by Promoting the Expression of Caspases-8, -9, -3, Apoptosis-Inducing Factor and Endonuclease G
Woong-Hyun Kim, Hyun-Ok Song, Hwa-Jung Choi, Ho-Il Bang, Du-Young Choi, Hyun Park
Int J Mol Sci. 2012; 13(9): 11912–11922. Published online 2012 Sep 20. doi: 10.3390/ijms130911912
PMCID:
PMC3472783
AbstractArticlePDF–1.2M
15.
Impact of promoter polymorphisms in key regulators of the intrinsic apoptosis pathway on the outcome of childhood acute lymphoblastic leukemia
Rocio Sanchez, Janick St-Cyr, Marie-Eve Lalonde, Jasmine Healy, Chantal Richer, Vincent Gagné, Caroline Laverdière, Lewis B. Silverman, Stephen E. Sallan, Donna Neuberg, Jeffery L. Kutok, Ekaterini A. Kritikou, Maja Krajinovic, Daniel Sinnett
Haematologica. 2014 Feb; 99(2): 314–321. doi: 10.3324/haematol.2013.085340
PMCID:
PMC3912962
AbstractArticlePDF–1002K
16.
No death without life: vital functions of apoptotic effectors
L Galluzzi, N Joza, E Tasdemir, MC Maiuri, M Hengartner, JM Abrams, N Tavernarakis, J Penninger, F Madeo, G Kroemer
Cell Death Differ. Author manuscript; available in PMC 2010 Aug 9.
Published in final edited form as: Cell Death Differ. 2008 Jul; 15(7): 1113–1123. Published online 2008 Feb 29. doi: 10.1038/cdd.2008.28
PMCID:
PMC2917777
AbstractArticlePDF–347K
17.
Identification of rare DNA variants in mitochondrial disorders with improved array-based sequencing
Wenyi Wang, Peidong Shen, Sreedevi Thiyagarajan, Shengrong Lin, Curtis Palm, Rita Horvath, Thomas Klopstock, David Cutler, Lynn Pique, Iris Schrijver, Ronald W. Davis, Michael Mindrinos, Terence P. Speed, Curt Scharfe
Nucleic Acids Res. 2011 Jan; 39(1): 44–58. Published online 2010 Sep 15. doi: 10.1093/nar/gkq750
PMCID:
PMC3017602
AbstractArticlePDF–1.4M
18.
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways
Mikko Taipale, George Tucker, Jian Peng, Irina Krykbaeva, Zhen-Yuan Lin, Brett Larsen, Hyungwon Choi, Bonnie Berger, Anne-Claude Gingras, Susan Lindquist
Cell. Author manuscript; available in PMC 2015 Jul 17.
Published in final edited form as: Cell. 2014 Jul 17; 158(2): 434–448. doi: 10.1016/j.cell.2014.05.039
PMCID:
PMC4104544
AbstractArticlePDF–3.2M
19.
The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin
Dragomir B. Krastev, Shudong Li, Yilun Sun, Andrew J. Wicks, Gwendoline Hoslett, Daniel Weekes, Luned M. Badder, Eleanor G. Knight, Rebecca Marlow, Mercedes Calvo Pardo, Lu Yu, Tanaji T. Talele, Jiri Bartek, Jyoti S. Choudhary, Yves Pommier, Stephen J. Pettitt, Andrew N. J. Tutt, Kristijan Ramadan, Christopher J. Lord
Nat Cell Biol. 2022; 24(1): 62–73. Published online 2022 Jan 10. doi: 10.1038/s41556-021-00807-6
PMCID:
PMC8760077
AbstractArticlePDF–12M
20.
Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome
Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584
PMCID:
PMC8769072
AbstractArticlePDF–2.9M

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