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Select item 112199181.

Antimicrobial peptide 2K4L inhibits the inflammatory response in macrophages and Caenorhabditis elegans and protects against LPS-induced septic shock in mice

Fangyu Ji, Guoxu Tian, Dejing Shang

Sci Rep. 2024; 14: 15093. Published online 2024 Jul 2. doi: 10.1038/s41598-024-64511-9

PMCID:: PMC11219918

Abstract Article PDF–6.2M

Select item 69024812.

The Pseudomonas aeruginosa accessory genome elements influence virulence towards Caenorhabditis elegans

Alejandro Vasquez-Rifo, Isana Veksler-Lublinsky, Zhenyu Cheng, Frederick M. Ausubel, Victor Ambros

Genome Biol. 2019; 20: 270. Published online 2019 Dec 10. doi: 10.1186/s13059-019-1890-1

PMCID:: PMC6902481

Abstract Article PDF–3.7M

Select item 60710423.

Transcriptome Analysis of C. elegans Reveals Novel Targets for DON Cytotoxicity

Rong Di, Hanzhong Zhang, Michael A. Lawton

Toxins (Basel) 2018 Jul; 10(7): 262. Published online 2018 Jun 27. doi: 10.3390/toxins10070262

PMCID:: PMC6071042

Abstract Article PDF–1.4M

Select item 59456364.

Probiotic Lactobacillus fermentum strain JDFM216 stimulates the longevity and immune response of Caenorhabditis elegans through a nuclear hormone receptor

Mi Ri Park, Sangdon Ryu, Brighton E. Maburutse, Nam Su Oh, Sae Hun Kim, Sejong Oh, Seong-Yeop Jeong, Do-Youn Jeong, Sangnam Oh, Younghoon Kim

Sci Rep. 2018; 8: 7441. Published online 2018 May 10. doi: 10.1038/s41598-018-25333-8

PMCID:: PMC5945636

Abstract Article PDF–1.9M

Select item 30981975.

A Decline in p38 MAPK Signaling Underlies Immunosenescence in Caenorhabditis elegans

Matthew J. Youngman, Zoë N. Rogers, Dennis H. Kim

PLoS Genet. 2011 May; 7(5): e1002082. Published online 2011 May 19. doi: 10.1371/journal.pgen.1002082

PMCID:: PMC3098197

Abstract Article PDF–707K

Select item 111125056.

Caenorhabditis elegans neuropeptide NLP-27 enhances neurodegeneration and paralysis in an opioid-like manner during fungal infection

Maria Pop, Anna-Lena Klemke, Lena Seidler, Nicole Wernet, Pietrina Loredana Steudel, Vanessa Baust, Elke Wohlmann, Reinhard Fischer

iScience. 2024 Apr 19; 27(4): 109484. Published online 2024 Mar 12. doi: 10.1016/j.isci.2024.109484

PMCID:: PMC11112505

Abstract Article PDF–3.2M

Select item 110214197.

Bacterial peptidoglycan acts as a digestive signal mediating host adaptation to diverse food resources in C. elegans

Fanrui Hao, Huimin Liu, Bin Qi

Nat Commun. 2024; 15: 3286. Published online 2024 Apr 16. doi: 10.1038/s41467-024-47530-y

PMCID:: PMC11021419

Abstract Article PDF–3.5M

Select item 109902738.

A diet of oxidative stress–adapted bacteria improves stress resistance and lifespan in C. elegans via p38-MAPK

Ajay Bhat, Rebecca L. Cox, Brice Graham Hendrickson, Nupur K. Das, Megan L. Schaller, Angela M. Tuckowski, Emily Wang, Yatrik M. Shah, Scott F. Leiser

Sci Adv. 2024 Apr 5; 10(14): eadk8823. Published online 2024 Apr 3. doi: 10.1126/sciadv.adk8823

PMCID:: PMC10990273

Abstract Article PDF–2.8M

Select item 103825259.

Modulating p38 MAPK signaling by proteostasis mechanisms supports tissue integrity during growth and aging

Wang Yuan, Yi M. Weaver, Svetlana Earnest, Clinton A. Taylor, IV, Melanie H. Cobb, Benjamin P. Weaver

Nat Commun. 2023; 14: 4543. Published online 2023 Jul 28. doi: 10.1038/s41467-023-40317-7

PMCID:: PMC10382525

Abstract Article PDF–2.5M

Select item 892366310.

Pathogen infection and cholesterol deficiency activate the C. elegans p38 immune pathway through a TIR-1/SARM1 phase transition

Nicholas D Peterson, Janneke D Icso, J Elizabeth Salisbury, Tomás Rodríguez, Paul R Thompson, Read Pukkila-Worley

eLife. 2022; 11: e74206. Published online 2022 Jan 31. doi: 10.7554/eLife.74206

PMCID:: PMC8923663

Abstract Article PDF–3.1M

Select item 885750511.

Sanguinarine promotes healthspan and innate immunity through a conserved mechanism of ROS-mediated PMK-1/SKN-1 activation

Fang Liu, Haijuan Wang, Xinting Zhu, Nian Jiang, Feng Pan, Changwei Song, Chunbo Yu, Changyan Yu, Ying Qin, Jing Hui, Sanhua Li, Yi Xiao, Yun Liu

iScience. 2022 Mar 18; 25(3): 103874. Published online 2022 Feb 4. doi: 10.1016/j.isci.2022.103874

PMCID:: PMC8857505

Abstract Article PDF–2.4M

Select item 855385312.

Probiotic-mediated p38 MAPK immune signaling prolongs the survival of Caenorhabditis elegans exposed to pathogenic bacteria

Miroslav Dinić, Stefan Jakovljević, Jelena Đokić, Nikola Popović, Dušan Radojević, Ivana Strahinić, Nataša Golić

Sci Rep. 2021; 11: 21258. Published online 2021 Oct 28. doi: 10.1038/s41598-021-00698-5

PMCID:: PMC8553853

Abstract Article PDF–1.9M

Select item 837038913.

Loss of Function of Scavenger Receptor SCAV-5 Protects C. elegans Against Pathogenic Bacteria

Aixiao Luo, Huiru Jing, Lei Yuan, Yanzhe Wang, Hui Xiao, Qian Zheng

Front Cell Infect Microbiol. 2021; 11: 593745. Published online 2021 Aug 3. doi: 10.3389/fcimb.2021.593745

PMCID:: PMC8370389

Abstract Article PDF–3.7M

Select item 752012314.

Lipopolysaccharide stimulates egg laying in Caenorhabditis elegans

Angela Ching-Yee Leung, Catherine Hughes, Jakob Gunderson, Myeongwoo Lee

MicroPubl Biol. 2020; 2020: 10.17912/micropub.biology.000308. Published online 2020 Sep 14. doi: 10.17912/micropub.biology.000308

PMCID:: PMC7520123

Article PDF–159K

Select item 721589915.

Innate Immunity in the C. elegans Intestine Is Programmed by a Neuronal Regulator of AWC Olfactory Neuron Development

Kyle J. Foster, Hilary K. Cheesman, Pengpeng Liu, Nicholas D. Peterson, Sarah M. Anderson, Read Pukkila-Worley

Cell Rep. Author manuscript; available in PMC 2020 May 12.

Published in final edited form as: Cell Rep. 2020 Apr 7; 31(1): 107478. doi: 10.1016/j.celrep.2020.03.042

PMCID:: PMC7215899

Abstract Article PDF–968K

Select item 705574116.

Inhibition of the oligosaccharyl transferase in Caenorhabditis elegans that compromises ER proteostasis suppresses p38-dependent protection against pathogenic bacteria

Dae-Eun Jeong, Yujin Lee, Seokjin Ham, Dongyeop Lee, Sujeong Kwon, Hae-Eun H. Park, Sun-Young Hwang, Joo-Yeon Yoo, Tae-Young Roh, Seung-Jae V. Lee

PLoS Genet. 2020 Mar; 16(3): e1008617. Published online 2020 Mar 4. doi: 10.1371/journal.pgen.1008617

PMCID:: PMC7055741

Abstract Article PDF–3.6M

Select item 699393217.

Caenorhabditis Intervention Testing Program: the tyrosine kinase inhibitor imatinib mesylate does not extend lifespan in nematodes

Anna L. Coleman-Hulbert, Erik Johnson, Christine A. Sedore, Stephen A. Banse, Max Guo, Monica Driscoll, Gordon J. Lithgow, Patrick C. Phillips

MicroPubl Biol. 2019; 2019: 10.17912/micropub.biology.000131. Published online 2019 Jul 3. doi: 10.17912/micropub.biology.000131

Correction in:: MicroPubl Biol. 2019; 2019: 10.17912/micropub.biology.000184.

Correction in:: MicroPubl Biol. 2019; 2019: 10.17912/micropub.biology.000144.

PMCID:: PMC6993932

Article PDF–1.2M

Select item 665729518.

Mitochondrial Reactive Oxygen Species Generated at the Complex-II Matrix or Intermembrane Space Microdomain Have Distinct Effects on Redox Signaling and Stress Sensitivity in Caenorhabditis elegans

Adam J. Trewin, Laura L. Bahr, Anmol Almast, Brandon J. Berry, Alicia Y. Wei, Thomas H. Foster, Andrew P. Wojtovich

Antioxid Redox Signal. 2019 Sep 20; 31(9): 594–607. Published online 2019 Jul 25. doi: 10.1089/ars.2018.7681

PMCID:: PMC6657295

Abstract Article PDF–971K

Select item 663720919.

The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity

Francis R. G. Amrit, Nikki Naim, Ramesh Ratnappan, Julia Loose, Carter Mason, Laura Steenberge, Brooke T. McClendon, Guoqiang Wang, Monica Driscoll, Judith L. Yanowitz, Arjumand Ghazi

Nat Commun. 2019; 10: 3042. Published online 2019 Jul 17. doi: 10.1038/s41467-019-10759-z