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Select item 87905741.

Cytohesin-2/ARNO: A Novel Bridge Between Cell Migration and Immunoregulation in Synovial Fibroblasts

Yilin Wang, Çağlar Çil, Margaret M. Harnett, Miguel A. Pineda

Front Immunol. 2021; 12: 809896. Published online 2022 Jan 12. doi: 10.3389/fimmu.2021.809896

PMCID:: PMC8790574

Abstract Article PDF–27M

Select item 69481922.

Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes

Sanchaita Das, Andrew W. Malaby, Agata Nawrotek, Wenhua Zhang, Mahel Zeghouf, Sarah Maslen, Mark Skehel, Srinivas Chakravarthy, Thomas C. Irving, Osman Bilsel, Jacqueline Cherfils, David G. Lambright

Structure. 2019 Dec 3; 27(12): 1782–1797.e7. doi: 10.1016/j.str.2019.09.007

PMCID:: PMC6948192

Abstract Article

Select item 5231823.

Structural determinants of phosphoinositide selectivity in splice variants of Grp1 family PH domains

Thomas C Cronin, Jonathan P DiNitto, Michael P Czech, David G Lambright

EMBO J. 2004 Sep 29; 23(19): 3711–3720. Published online 2004 Sep 9. doi: 10.1038/sj.emboj.7600388

PMCID:: PMC523182

Abstract Article PDF–476K

Select item 86610604.

The synaptic scaffolding protein CNKSR2 interacts with CYTH2 to mediate hippocampal granule cell development

Hidenori Ito, Rika Morishita, Mariko Noda, Tomoki Ishiguro, Masashi Nishikawa, Koh-ichi Nagata

J Biol Chem. 2021 Dec; 297(6): 101427. Published online 2021 Nov 17. doi: 10.1016/j.jbc.2021.101427

PMCID:: PMC8661060

Abstract Article PDF–4.1M

Select item 42546185.

The RLIP76 N-terminus binds ARNO to regulate PI 3-kinase, Arf6 and Rac signaling, cell spreading and migration

Seunghyung Lee, Jeremy G.T. Wurtzel, Lawrence E. Goldfinger

Biochem Biophys Res Commun. Author manuscript; available in PMC 2015 Nov 28.

Published in final edited form as: Biochem Biophys Res Commun. 2014 Oct 30; 454(4): 560–565. Published online 2014 Oct 30. doi: 10.1016/j.bbrc.2014.10.114

PMCID:: PMC4254618

Abstract Article PDF–769K

Select item 46444386.

RLIP76 regulates Arf6-dependent cell spreading and migration by linking ARNO with activated R-Ras at recycling endosomes

Jeremy G.T. Wurtzel, Seunghyung Lee, Sharad S. Singhal, Sanjay Awasthi, Mark H. Ginsberg, Lawrence E. Goldfinger

Biochem Biophys Res Commun. Author manuscript; available in PMC 2016 Nov 27.

Published in final edited form as: Biochem Biophys Res Commun. 2015 Nov 27; 467(4): 785–791. Published online 2015 Oct 20. doi: 10.1016/j.bbrc.2015.10.064

PMCID:: PMC4644438

Abstract Article PDF–994K

Select item 42388087.

Cytohesin-2 phosphorylation by protein kinase C relieves the constitutive suppression of platelet dense granule secretion by ADP-ribosylation factor 6

M T J van den Bosch, A W Poole, I Hers

J Thromb Haemost. 2014 May; 12(5): 726–735. Published online 2014 May 22. doi: 10.1111/jth.12542

PMCID:: PMC4238808

Abstract Article PDF–666K

Select item 21560388.

Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide Dependent Grp1 Family Arf GTPase Exchange Factors

Jonathan P. DiNitto, Anna Delprato, Meng-Tse Gabe Lee, Thomas C. Cronin, Shaohui Huang, Adilson Guilherme, Michael P. Czech, David G. Lambright

Mol Cell. Author manuscript; available in PMC 2007 Dec 26.

Published in final edited form as: Mol Cell. 2007 Nov 30; 28(4): 569–583. doi: 10.1016/j.molcel.2007.09.017

PMCID:: PMC2156038

Abstract Article PDF–4.3M

Select item 29113109.

Cytohesin-2/ARNO, through Its Interaction with Focal Adhesion Adaptor Protein Paxillin, Regulates Preadipocyte Migration via the Downstream Activation of Arf6

Tomohiro Torii, Yuki Miyamoto, Atsushi Sanbe, Kohji Nishimura, Junji Yamauchi, Akito Tanoue

J Biol Chem. 2010 Jul 30; 285(31): 24270–24281. Published online 2010 Jun 4. doi: 10.1074/jbc.M110.125658

PMCID:: PMC2911310

Abstract Article PDF–2.9M

Select item 358141010.

The N Termini of a-Subunit Isoforms Are Involved in Signaling between Vacuolar H⁺-ATPase (V-ATPase) and Cytohesin-2

Hiroyuki Hosokawa, Phat Vinh Dip, Maria Merkulova, Anastasia Bakulina, Zhenjie Zhuang, Ashok Khatri, Xiaoying Jian, Shawn M. Keating, Stephanie A. Bueler, John L. Rubinstein, Paul A. Randazzo, Dennis A. Ausiello, Gerhard Grüber, Vladimir Marshansky

J Biol Chem. 2013 Feb 22; 288(8): 5896–5913. Published online 2013 Jan 3. doi: 10.1074/jbc.M112.409169

PMCID:: PMC3581410

Abstract Article PDF–4.1M

Select item 281890011.

FRMD4A regulates epithelial polarity by connecting Arf6 activation with the PAR complex

Junichi Ikenouchi, Masato Umeda

Proc Natl Acad Sci U S A. 2010 Jan 12; 107(2): 748–753. Published online 2009 Dec 22. doi: 10.1073/pnas.0908423107

PMCID:: PMC2818900

Abstract Article PDF–1.2M

Select item 638200612.

A crucial role for Arf6 in the response of commissural axons to Slit

Mariko Kinoshita-Kawada, Hiroshi Hasegawa, Tsunaki Hongu, Shigeru Yanagi, Yasunori Kanaho, Ichiro Masai, Takayasu Mishima, Xiaoping Chen, Yoshio Tsuboi, Yi Rao, Junichi Yuasa-Kawada, Jane Y. Wu

Development. 2019 Feb 1; 146(3): dev172106. Published online 2019 Feb 4. doi: 10.1242/dev.172106

PMCID:: PMC6382006

Abstract Article

Select item 1020895813.

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome

Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh

Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5

PMCID:: PMC10208958

Abstract Article PDF–7.0M

Select item 564508214.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Abstract Article PDF–2.3M

Select item 18788515.

A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome

Jens Hansen, Thomas Floss, Petra Van Sloun, Ernst-Martin Füchtbauer, Franz Vauti, Hans-Hennig Arnold, Frank Schnütgen, Wolfgang Wurst, Harald von Melchner, Patricia Ruiz

Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17): 9918–9922. Published online 2003 Aug 6. doi: 10.1073/pnas.1633296100

PMCID:: PMC187885

Abstract Article PDF–287K

Select item 16551116.

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells

Doug Stryke, Michiko Kawamoto, Conrad C. Huang, Susan J. Johns, Leslie A. King, Courtney A. Harper, Elaine C. Meng, Roy E. Lee, Alice Yee, Larry L'Italien, Pao-Tien Chuang, Stephen G. Young, William C. Skarnes, Patricia C. Babbitt, Thomas E. Ferrin

Nucleic Acids Res. 2003 Jan 1; 31(1): 278–281. doi: 10.1093/nar/gkg064

PMCID:: PMC165511

Abstract Article PDF–217K

Select item 141356817.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086

PMCID:: PMC1413568

Article PDF–99K

Select item 793877018.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 1683319.

Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray

Tetsuya S. Tanaka, Saied A. Jaradat, Meng K. Lim, George J. Kargul, Xiaohong Wang, Marija J. Grahovac, Serafino Pantano, Yuri Sano, Yulan Piao, Ramaiah Nagaraja, Hirofumi Doi, William H. Wood, III, Kevin G. Becker, Minoru S. H. Ko

Proc Natl Acad Sci U S A. 2000 Aug 1; 97(16): 9127–9132. doi: 10.1073/pnas.97.16.9127

PMCID:: PMC16833

Abstract Article PDF–847K

Select item 255627020.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Abstract Article PDF–493K

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