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Select item 104757761.

CCL21‐Ser expression in melanoma cells recruits CCR7⁺ naïve T cells to tumor tissues and promotes tumor growth

Megumi Miyamoto, Yuki Kawato, Ryonosuke Fujie, Kaoru Kurowarabe, Kakeru Fujiwara, Reika Nobusawa, Ryota Hayashi, Kei Iida, Izumi Ohigashi, Haruko Hayasaka

Cancer Sci. 2023 Sep; 114(9): 3509–3522. Published online 2023 Jul 8. doi: 10.1111/cas.15902

PMCID:: PMC10475776

Abstract Article PDF–2.2M

Select item 31820542.

DC mobilization from the skin requires docking to immobilized CCL21 on lymphatic endothelium and intralymphatic crawling

Orna Tal, Hwee Ying Lim, Irina Gurevich, Idan Milo, Zohar Shipony, Lai Guan Ng, Veronique Angeli, Guy Shakhar

J Exp Med. 2011 Sep 26; 208(10): 2141–2153. doi: 10.1084/jem.20102392

PMCID:: PMC3182054

Abstract Article PDF–2.9M

Select item 30869063.

Novel CCL21-Vault Nanocapsule Intratumoral Delivery Inhibits Lung Cancer Growth

Upendra K. Kar, Minu K. Srivastava, Åsa Andersson, Felicita Baratelli, Min Huang, Valerie A. Kickhoefer, Steven M. Dubinett, Leonard H. Rome, Sherven Sharma

PLoS One. 2011; 6(5): e18758. Published online 2011 May 3. doi: 10.1371/journal.pone.0018758

PMCID:: PMC3086906

Abstract Article PDF–443K

Select item 21958044.

The Cc Chemokine Thymus-Derived Chemotactic Agent 4 (Tca-4, Secondary Lymphoid Tissue Chemokine, 6ckine, Exodus-2) Triggers Lymphocyte Function–Associated Antigen 1–Mediated Arrest of Rolling T Lymphocytes in Peripheral Lymph Node High Endothelial Venules

Jens V. Stein, Antal Rot, Yi Luo, Manjunath Narasimhaswamy, Hideki Nakano, Michael D. Gunn, Akio Matsuzawa, Elizabeth J. Quackenbush, Martin E. Dorf, Ulrich H. von Andrian

J Exp Med. 2000 Jan 3; 191(1): 61–76. doi: 10.1084/jem.191.1.61

PMCID:: PMC2195804

Abstract Article PDF–410K

Select item 21929145.

Mice Lacking Expression of Secondary Lymphoid Organ Chemokine Have Defects in Lymphocyte Homing and Dendritic Cell Localization

Michael D. Gunn, Shigeru Kyuwa, Carmen Tam, Terutaka Kakiuchi, Akio Matsuzawa, Lewis T. Williams, Hideki Nakano

J Exp Med. 1999 Feb 1; 189(3): 451–460. doi: 10.1084/jem.189.3.451

PMCID:: PMC2192914

Abstract Article PDF–563K

Select item 79711316.

ACKR4 restrains antitumor immunity by regulating CCL21

Carly E. Whyte, Maleika Osman, Ervin E. Kara, Caitlin Abbott, Jade Foeng, Duncan R. McKenzie, Kevin A. Fenix, Yuka Harata-Lee, Kerrie L. Foyle, Sarah T. Boyle, Marina Kochetkova, Amelia Roman Aguilera, Jiajie Hou, Xian-Yang Li, Mark A. Armstrong, Stephen M. Pederson, Iain Comerford, Mark J. Smyth, Shaun R. McColl

J Exp Med. 2020 Jun 1; 217(6): e20190634. Published online 2020 Apr 14. doi: 10.1084/jem.20190634

Expression of Concern in:: J Exp Med. 2023 Dec 4; 220(12): e2019063411202023e.

PMCID:: PMC7971131

Abstract Article PDF–3.1M

Select item 64356737.

CCL21/CCR7 axis regulating juvenile cartilage repair can enhance cartilage healing in adults

Zenta Joutoku, Tomohiro Onodera, Masatake Matsuoka, Kentaro Homan, Daisuke Momma, Rikiya Baba, Kazutoshi Hontani, Masanari Hamasaki, Shinji Matsubara, Ryosuke Hishimura, Norimasa Iwasaki

Sci Rep. 2019; 9: 5165. Published online 2019 Mar 26. doi: 10.1038/s41598-019-41621-3

PMCID:: PMC6435673

Abstract Article PDF–4.2M

Select item 42331368.

Role of CCL19/21 and its possible signaling through CXCR3 in development of metallophillic macrophages in the mouse thymus

Novica M. Milićević, Miloš D. Miljković, Živana Milićević, Milica Labudović-Borović, Xiaoping Wang, Martti Laan, Pärt Peterson, Troy D. Randall, Jürgen Westermann

Histochem Cell Biol. Author manuscript; available in PMC 2014 Nov 16.

Published in final edited form as: Histochem Cell Biol. 2011 Jun; 135(6): 593–601. Published online 2011 May 25. doi: 10.1007/s00418-011-0818-y

PMCID:: PMC4233136

Abstract Article PDF–967K

Select item 21933409.

Mice Lacking Expression of the Chemokines Ccl21-Ser and Ccl19 (plt Mice) Demonstrate Delayed but Enhanced T Cell Immune Responses

Shigeyuki Mori, Hideki Nakano, Kentaro Aritomi, Chrong-Reen Wang, Michael D. Gunn, Terutaka Kakiuchi

J Exp Med. 2001 Jan 15; 193(2): 207–218. doi: 10.1084/jem.193.2.207

PMCID:: PMC2193340

Abstract Article PDF–367K

Select item 108827610.

Antigen-Engaged B Cells Undergo Chemotaxis toward the T Zone and Form Motile Conjugates with Helper T Cells

Takaharu Okada, Mark J Miller, Ian Parker, Matthew F Krummel, Margaret Neighbors, Suzanne B Hartley, Anne O'Garra, Michael D Cahalan, Jason G Cyster

PLoS Biol. 2005 Jun; 3(6): e150. Published online 2005 May 3. doi: 10.1371/journal.pbio.0030150

PMCID:: PMC1088276

Abstract Article PDF–732K

Select item 1882611.

Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse

Sanjiv A. Luther, H. Lucy Tang, Paul L. Hyman, Andrew G. Farr, Jason G. Cyster

Proc Natl Acad Sci U S A. 2000 Nov 7; 97(23): 12694–12699. doi: 10.1073/pnas.97.23.12694

PMCID:: PMC18826

Abstract Article PDF–532K

Select item 603622912.

Formation of the Intrathymic Dendritic Cell Pool Requires CCL21-Mediated Recruitment of CCR7⁺ Progenitors to the Thymus

Emilie J. Cosway, Izumi Ohigashi, Karin Schauble, Sonia M. Parnell, William E. Jenkinson, Sanjiv Luther, Yousuke Takahama, Graham Anderson

J Immunol. 2018 Jul 15; 201(2): 516–523. Published online 2018 May 21. doi: 10.4049/jimmunol.1800348

PMCID:: PMC6036229

Abstract Article PDF–1.2M

Select item 550243113.

Essential role of CCL21 in establishment of central self-tolerance in T cells

Mina Kozai, Yuki Kubo, Tomoya Katakai, Hiroyuki Kondo, Hiroshi Kiyonari, Karin Schaeuble, Sanjiv A. Luther, Naozumi Ishimaru, Izumi Ohigashi, Yousuke Takahama

J Exp Med. 2017 Jul 3; 214(7): 1925–1935. doi: 10.1084/jem.20161864

PMCID:: PMC5502431

Abstract Article PDF–2.3M

Select item 481962014.

Graft Site Microenvironment Determines Dendritic Cell Trafficking Through the CCR7-CCL19/21 Axis

Jing Hua, William Stevenson, Thomas H. Dohlman, Takenori Inomata, Maryam Tahvildari, Narghes Calcagno, Negar Pirmadjid, Zahra Sadrai, Sunil K. Chauhan, Reza Dana

Invest Ophthalmol Vis Sci. 2016 Mar; 57(3): 1457–1467. Published online 2016 Mar 31. doi: 10.1167/iovs.15-17551

PMCID:: PMC4819620

Abstract Article PDF–1.6M

Select item 387144215.

JAK tyrosine kinases promote hierarchical activation of Rho and Rap modules of integrin activation

Alessio Montresor, Matteo Bolomini-Vittori, Lara Toffali, Barbara Rossi, Gabriela Constantin, Carlo Laudanna

J Cell Biol. 2013 Dec 23; 203(6): 1003–1019. doi: 10.1083/jcb.201303067

PMCID:: PMC3871442

Abstract Article PDF–3.4M

Select item 310199616.

Neuronal CCL21 up-regulates microglia P2X4 expression and initiates neuropathic pain development

Knut Biber, Makoto Tsuda, Hidetoshi Tozaki-Saitoh, Keiko Tsukamoto, Emika Toyomitsu, Takahiro Masuda, Hendrikus Boddeke, Kazuhide Inoue

EMBO J. 2011 May 4; 30(9): 1864–1873. Published online 2011 Mar 25. doi: 10.1038/emboj.2011.89

PMCID:: PMC3101996

Abstract Article PDF–832K

Select item 221192817.

Thymic T Cell Development and Progenitor Localization Depend on CCR7

Ana Misslitz, Oliver Pabst, Gabriele Hintzen, Lars Ohl, Elisabeth Kremmer, Howard T. Petrie, Reinhold Förster

J Exp Med. 2004 Aug 16; 200(4): 481–491. doi: 10.1084/jem.20040383

PMCID:: PMC2211928

Abstract Article PDF–2.7M

Select item 219565918.

The Reduced Expression of 6ckine in the plt Mouse Results from the Deletion of One of Two 6ckine Genes

Galya Vassileva, Hortensia Soto, Albert Zlotnik, Hideki Nakano, Terutaka Kakiuchi, Joseph A. Hedrick, Sergio A. Lira

J Exp Med. 1999 Oct 18; 190(8): 1183–1188. doi: 10.1084/jem.190.8.1183

PMCID:: PMC2195659

Abstract Article PDF–147K

Select item 219400919.

Chemokine Requirements for B Cell Entry to Lymph Nodes and Peyer's Patches

Takaharu Okada, Vu N. Ngo, Eric H. Ekland, Reinhold Förster, Martin Lipp, Dan R. Littman, Jason G. Cyster

J Exp Med. 2002 Jul 1; 196(1): 65–75. doi: 10.1084/jem.20020201

PMCID:: PMC2194009

Abstract Article PDF–488K

Select item 1009780920.

Embryonic keratin19⁺ progenitors generate multiple functionally distinct progeny to maintain epithelial diversity in the adult thymus medulla

Beth Lucas, Andrea J. White, Fabian Klein, Clara Veiga-Villauriz, Adam Handel, Andrea Bacon, Emilie J. Cosway, Kieran D. James, Sonia M. Parnell, Izumi Ohigashi, Yousuke Takahama, William E. Jenkinson, Georg A. Hollander, Wei-Yu Lu, Graham Anderson

Nat Commun. 2023; 14: 2066. Published online 2023 Apr 12. doi: 10.1038/s41467-023-37589-4