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Items: 1 to 20 of 29

1.
Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning
Cheng Zhang, Mengnan Shi, Woonghee Kim, Muhammad Arif, Martina Klevstig, Xiangyu Li, Hong Yang, Cemil Bayram, Ismail Bolat, Özlem Özdemir Tozlu, Ahmet Hacımuftuoglu, Serkan Yıldırım, Jihad Sebhaoui, Shazia Iqbal, Yongjun Wei, Xiaojing Shi, Jens Nielsen, Hasan Turkez, Mathias Uhlen, Jan Boren, Adil Mardinoglu
eBioMedicine. 2022 Sep; 83: 104214. Published online 2022 Aug 18. doi: 10.1016/j.ebiom.2022.104214
Correction in:
eBioMedicine. 2024 Jul; 105: 105224.
PMCID:
PMC9420484
AbstractArticlePDF–4.4M
2.
The mouse Char10 locus regulates severity of pyruvate kinase deficiency and susceptibility to malaria
Aurélie Laroque, Gundula Min-Oo, Mifong Tam, Prem Ponka, Mary M. Stevenson, Philippe Gros
PLoS One. 2017; 12(5): e0177818. Published online 2017 May 18. doi: 10.1371/journal.pone.0177818
PMCID:
PMC5436716
AbstractArticlePDF–8.0M
3.
Liver Pyruvate Kinase Promotes NAFLD/NASH in Both Mice and Humans in a Sex-Specific Manner
Karthickeyan Chella Krishnan, Raquel R. Floyd, Simon Sabir, Dulshan W. Jayasekera, Paola V. Leon-Mimila, Anthony E. Jones, Angel A. Cortez, Varun Shravah, Miklós Péterfy, Linsey Stiles, Samuel Canizales-Quinteros, Ajit S. Divakaruni, Adriana Huertas-Vazquez, Aldons J. Lusis
Cell Mol Gastroenterol Hepatol. 2021; 11(2): 389–406. Published online 2020 Sep 14. doi: 10.1016/j.jcmgh.2020.09.004
PMCID:
PMC7788245
AbstractArticlePDF–4.6M
4.
Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase
Roger W. Hunter, Curtis C. Hughey, Louise Lantier, Elias I. Sundelin, Mark Peggie, Elton Zeqiraj, Frank Sicheri, Niels Jessen, David H. Wasserman, Kei Sakamoto
Nat Med. Author manuscript; available in PMC 2019 Feb 27.
Published in final edited form as: Nat Med. 2018 Sep; 24(9): 1395–1406. Published online 2018 Aug 27. doi: 10.1038/s41591-018-0159-7
PMCID:
PMC6207338
AbstractArticlePDF–2.3M
5.
Energetic coupling between an oxidizable cysteine and the phosphorylatable N-terminus of human liver pyruvate kinase
Todd Holyoak, Bing Zhang, Junpeng Deng, Qingling Tang, Charulata B. Prasannan, Aron W. Fenton
Biochemistry. Author manuscript; available in PMC 2014 Jan 22.
Published in final edited form as: Biochemistry. 2013 Jan 22; 52(3): 466–476. Published online 2013 Jan 11. doi: 10.1021/bi301341r
PMCID:
PMC3572911
AbstractArticlePDF–1.4M
6.
Pyruvate kinase deficiency confers susceptibility to Salmonella typhimurium infection in mice
Marie-France Roy, Noémie Riendeau, Christian Bédard, Pierre Hélie, Gundula Min-Oo, Karine Turcotte, Philippe Gros, François Canonne-Hergaux, Danielle Malo
J Exp Med. 2007 Nov 26; 204(12): 2949–2961. doi: 10.1084/jem.20062606
PMCID:
PMC2118530
AbstractArticlePDF–3.2M
7.
Complex genetic control of susceptibility to malaria: positional cloning of the Char9 locus
Gundula Min-Oo, Anny Fortin, Giuseppina Pitari, Mifong Tam, Mary M. Stevenson, Philippe Gros
J Exp Med. 2007 Mar 19; 204(3): 511–524. doi: 10.1084/jem.20061252
PMCID:
PMC2137903
AbstractArticlePDF–2.6M
8.
Characterization of glycolytic enzyme interactions with murine erythrocyte membranes in wild-type and membrane protein knockout mice
M. Estela Campanella, Haiyan Chu, Nancy J. Wandersee, Luanne L. Peters, Narla Mohandas, Diana M. Gilligan, Philip S. Low
Blood. 2008 Nov 1; 112(9): 3900–3906. Prepublished online 2008 Aug 12. doi: 10.1182/blood-2008-03-146159
PMCID:
PMC2572807
AbstractArticle
9.
Image-based quantification of histological features as a function of spatial location using the Tissue Positioning System
Ruichen Rong, Yonglong Wei, Lin Li, Tao Wang, Hao Zhu, Guanghua Xiao, Yunguan Wang
eBioMedicine. 2023 Aug; 94: 104698. Published online 2023 Jul 13. doi: 10.1016/j.ebiom.2023.104698
PMCID:
PMC10365985
AbstractArticlePDF–5.4M
10.
Liver homeostasis is maintained by midlobular zone 2 hepatocytes
Yonglong Wei, Yunguan G. Wang, Yuemeng Jia, Lin Li, Jung Yoon, Shuyuan Zhang, Zixi Wang, Yu Zhang, Min Zhu, Tripti Sharma, Yu-Hsuan Lin, Meng-Hsiung Hsieh, Jeffrey H. Albrecht, Phuong T. Le, Clifford J. Rosen, Tao Wang, Hao Zhu
Science. Author manuscript; available in PMC 2021 Oct 7.
Published in final edited form as: Science. 2021 Feb 26; 371(6532): eabb1625. doi: 10.1126/science.abb1625
PMCID:
PMC8496420
AbstractArticlePDF–6.4M
11.
Fim-1, Fim-2/c-fms, and Fim-3, three common integration sites of Friend murine leukemia virus in myeloblastic leukemias, map to mouse chromosomes 13, 18, and 3, respectively.
B Sola, D Simon, M G Mattéi, S Fichelson, D Bordereaux, P E Tambourin, J L Guenet, S Gisselbrecht
J Virol. 1988 Nov; 62(11): 3973–3978. doi: 10.1128/jvi.62.11.3973-3978.1988
PMCID:
PMC253824
SummaryPage BrowsePDF–1.2M
12.
Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma
Talya L. Dayton, Vasilena Gocheva, Kathryn M. Miller, William J. Israelsen, Arjun Bhutkar, Clary B. Clish, Shawn M. Davidson, Alba Luengo, Roderick T. Bronson, Tyler Jacks, Matthew G. Vander Heiden
Genes Dev. 2016 May 1; 30(9): 1020–1033. doi: 10.1101/gad.278549.116
PMCID:
PMC4863734
AbstractArticlePDF–583K
13.
Krüppel-Like Factor 1 (KLF1), KLF2, and Myc Control a Regulatory Network Essential for Embryonic Erythropoiesis
Christopher J. Pang, Wafaa Lemsaddek, Yousef N. Alhashem, Cornelius Bondzi, Latasha C. Redmond, Nicolas Ah-Son, Catherine I. Dumur, Kellie J. Archer, Jack L. Haar, Joyce A. Lloyd, Marie Trudel
Mol Cell Biol. 2012 Jul; 32(13): 2628–2644. doi: 10.1128/MCB.00104-12
PMCID:
PMC3434496
AbstractArticlePDF–1.8M
14.
Inactivation of the winged helix transcription factor HNF3α affects glucose homeostasis and islet glucagon gene expression in vivo
Klaus H. Kaestner, Jonathan Katz, Yuanfang Liu, Daniel J. Drucker, Günther Schütz
Genes Dev. 1999 Feb 15; 13(4): 495–504. doi: 10.1101/gad.13.4.495
PMCID:
PMC316473
AbstractArticlePDF–3.8M
15.
Rat Gene Mapping Using Pcr-Analyzed Microsatellites
T. Serikawa, T. Kuramoto, P. Hilbert, M. Mori, J. Yamada, C. J. Dubay, K. Lindpainter, D. Ganten, J. L. Guenet, G. M. Lathrop, J. S. Beckmann
Genetics. 1992 Jul; 131(3): 701–721. doi: 10.1093/genetics/131.3.701
PMCID:
PMC1205041
SummaryPDF–1.5M
16.
In vivo role of the HNF4α AF-1 activation domain revealed by exon swapping
Nadège Briançon, Mary C Weiss
EMBO J. 2006 Mar 22; 25(6): 1253–1262. Published online 2006 Feb 23. doi: 10.1038/sj.emboj.7601021
PMCID:
PMC1422155
AbstractArticlePDF–593K
17.
An analysis of expression patterns of genes encoding proteins with catalytic activities
Murat Cankaya, Ana Martinez Hernandez, Mehmet Ciftci, Sukru Beydemir, Hasan Ozdemir, Harun Budak, Ilhami Gulcin, Veysel Comakli, Tufan Emircupani, Deniz Ekinci, Muslum Kuzu, Qiuhong Jiang, Gregor Eichele, Omer Irfan Kufrevioglu
BMC Genomics. 2007; 8: 232. Published online 2007 Jul 12. doi: 10.1186/1471-2164-8-232
PMCID:
PMC1976134
AbstractArticlePDF–1.5M
18.
Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series
Caitlyn E. Bowman, Liang Zhao, Thomas Hartung, Michael J. Wolfgang
Mol Cell Biol. 2016 Aug 1; 36(15): 2089–2104. Prepublished online 2016 May 23. Published online 2016 Jul 14. doi: 10.1128/MCB.00166-16
PMCID:
PMC4946427
AbstractArticlePDF–3.4M
19.
Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development
Vinay Bulusu, Nicole Prior, Marteinn T. Snaebjornsson, Andreas Kuehne, Katharina F. Sonnen, Jana Kress, Frank Stein, Carsten Schultz, Uwe Sauer, Alexander Aulehla
Dev Cell. 2017 Feb 27; 40(4): 331–341.e4. doi: 10.1016/j.devcel.2017.01.015
PMCID:
PMC5337618
AbstractArticle
20.
Targeting a Complex Transcriptome: The Construction of the Mouse Full-Length cDNA Encyclopedia
Piero Carninci, Kazunori Waki, Toshiyuki Shiraki, Hideaki Konno, Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Takahiro Arakawa, Yoshiyuki Ishii, Daisuke Sasaki, Hidemasa Bono, Shinji Kondo, Yuichi Sugahara, Rintaro Saito, Naoki Osato, Shiro Fukuda, Kenjiro Sato, Akira Watahiki, Tomoko Hirozane-Kishikawa, Mari Nakamura, Yuko Shibata, Ayako Yasunishi, Noriko Kikuchi, Atsushi Yoshiki, Moriaki Kusakabe, Stefano Gustincich, Kirk Beisel, William Pavan, Vassilis Aidinis, Akira Nakagawara, William A. Held, Hiroo Iwata, Tomohiro Kono, Hiromitsu Nakauchi, Paul Lyons, Christine Wells, David A. Hume, Michela Fagiolini, Takao K. Hensch, Michelle Brinkmeier, Sally Camper, Junji Hirota, Peter Mombaerts, Masami Muramatsu, Yasushi Okazaki, Jun Kawai, Yoshihide Hayashizaki
Genome Res. 2003 Jun; 13(6b): 1273–1289. doi: 10.1101/gr.1119703
PMCID:
PMC403712
AbstractArticlePDF–770K

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