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Select item 70529851.

PIP5k1β controls bone homeostasis through modulating both osteoclast and osteoblast differentiation

Xiaoying Zhao, Penglei Cui, Guoli Hu, Chuandong Wang, Lei Jiang, Jingyu Zhao, Jiake Xu, Xiaoling Zhang

J Mol Cell Biol. 2020 Jan; 12(1): 55–70. Published online 2019 Apr 16. doi: 10.1093/jmcb/mjz028

PMCID:: PMC7052985

Abstract Article PDF–2.7M

Select item 55727072.

Regulation of HGF-induced hepatocyte proliferation by the small GTPase Arf6 through the PIP₂-producing enzyme PIP5K1A

Meng-Tsz Tsai, Naohiro Katagiri, Norihiko Ohbayashi, Kenichi Iwasaki, Nobuhiro Ohkohchi, Shih-Torng Ding, Yasunori Kanaho, Yuji Funakoshi

Sci Rep. 2017; 7: 9438. Published online 2017 Aug 25. doi: 10.1038/s41598-017-09633-z

PMCID:: PMC5572707

Abstract Article PDF–8.2M

Select item 22130973.

Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I α

Junko Sasaki, Takehiko Sasaki, Masakazu Yamazaki, Kunie Matsuoka, Choji Taya, Hiroshi Shitara, Shunsuke Takasuga, Miki Nishio, Katsunori Mizuno, Teiji Wada, Hideyuki Miyazaki, Hiroshi Watanabe, Ryota Iizuka, Shuichi Kubo, Shigeo Murata, Tomoki Chiba, Tomohiko Maehama, Koichi Hamada, Hiroyuki Kishimoto, Michael A. Frohman, Keiji Tanaka, Josef M. Penninger, Hiromichi Yonekawa, Akira Suzuki, Yasunori Kanaho

J Exp Med. 2005 Mar 21; 201(6): 859–870. doi: 10.1084/jem.20041891

PMCID:: PMC2213097

Abstract Article PDF–2.7M

Select item 21941754.

Arf6 and Phosphoinositol-4-Phosphate-5-Kinase Activities Permit Bypass of the Rac1 Requirement for β₁ Integrin–mediated Bacterial Uptake

Ka-Wing Wong, Ralph R. Isberg

J Exp Med. 2003 Aug 18; 198(4): 603–614. doi: 10.1084/jem.20021363

PMCID:: PMC2194175

Abstract Article PDF–445K

Select item 30283455.

Phosphatidylinositol-4-Phosphate-5-Kinase α Deficiency Alters Dynamics of Glucose-Stimulated Insulin Release to Improve Glucohomeostasis and Decrease Obesity in Mice

Ping Huang, Oladapo Yeku, Haihong Zong, Phyllis Tsang, Wenjuan Su, Xiao Yu, Shuzhi Teng, Mary Osisami, Yasunori Kanaho, Jeffrey E. Pessin, Michael A. Frohman

Diabetes. 2011 Feb; 60(2): 454–463. Published online 2011 Jan 21. doi: 10.2337/db10-0614

PMCID:: PMC3028345

Abstract Article PDF–1.9M

Select item 25445796.

Loss of PIP5KIβ demonstrates that PIP5KI isoform-specific PIP₂ synthesis is required for IP₃ formation

Yanfeng Wang, Xinsheng Chen, Lurong Lian, Tang Tang, Timothy J. Stalker, Takehiko Sasaki, Lawrence F. Brass, John K. Choi, John H. Hartwig, Charles S. Abrams

Proc Natl Acad Sci U S A. 2008 Sep 16; 105(37): 14064–14069. Published online 2008 Sep 4. doi: 10.1073/pnas.0804139105

Correction in:: Proc Natl Acad Sci U S A. 2009 Jan 27; 106(4): 1291.

PMCID:: PMC2544579

Abstract Article PDF–1.2M

Select item 35470697.

PIP5KIβ Selectively Modulates Apical Endocytosis in Polarized Renal Epithelial Cells

Christina M. Szalinski, Christopher J. Guerriero, Wily G. Ruiz, Brianne E. Docter, Youssef Rbaibi, Núria M. Pastor-Soler, Gerard Apodaca, Manojkumar A. Puthenveedu, Ora A. Weisz

PLoS One. 2013; 8(1): e53790. Published online 2013 Jan 16. doi: 10.1371/journal.pone.0053790

PMCID:: PMC3547069

Abstract Article PDF–1.1M

Select item 34762638.

Phosphatidylinositol-4-phosphate 5-Kinase Isoforms Exhibit Acyl Chain Selectivity for Both Substrate and Lipid Activator

Yulia V. Shulga, Richard A. Anderson, Matthew K. Topham, Richard M. Epand

J Biol Chem. 2012 Oct 19; 287(43): 35953–35963. Published online 2012 Sep 1. doi: 10.1074/jbc.M112.370155

PMCID:: PMC3476263

Abstract Article PDF–1.3M

Select item 27048879.

The β- and γ-isoforms of type I PIP5K regulate distinct stages of Ca²⁺ signaling in mast cells

Lavanya Vasudevan, Andreas Jeromin, Laura Volpicelli-Daley, Pietro De Camilli, David Holowka, Barbara Baird

J Cell Sci. 2009 Jul 15; 122(14): 2567–2574. Published online 2009 Jun 23. doi: 10.1242/jcs.048124

PMCID:: PMC2704887

Abstract Article

Select item 1049814610.

FAM122A Is Required for Mesendodermal and Cardiac Differentiation of Embryonic Stem Cells

Yun-Sheng Yang, Man-Hua Liu, Zhao-Wen Yan, Guo-Qiang Chen, Ying Huang

Stem Cells. 2023 Apr; 41(4): 354–367. Published online 2023 Jan 30. doi: 10.1093/stmcls/sxad008

PMCID:: PMC10498146

Abstract Article PDF–29M

Select item 351655711.

Construction of a Global Pain Systems Network Highlights Phospholipid Signaling as a Regulator of Heat Nociception

G. Gregory Neely, Shuan Rao, Michael Costigan, Norbert Mair, Ildiko Racz, Giedre Milinkeviciute, Arabella Meixner, Swetha Nayanala, Robert S. Griffin, Inna Belfer, Feng Dai, Shad Smith, Luda Diatchenko, Stefano Marengo, Bernhard J. Haubner, Maria Novatchkova, Dustin Gibson, William Maixner, J. Andrew Pospisilik, Emilio Hirsch, Ian Q. Whishaw, Andreas Zimmer, Vaijayanti Gupta, Junko Sasaki, Yasunori Kanaho, Takehiko Sasaki, Michaela Kress, Clifford J. Woolf, Josef M. Penninger

PLoS Genet. 2012 Dec; 8(12): e1003071. Published online 2012 Dec 6. doi: 10.1371/journal.pgen.1003071

PMCID:: PMC3516557

Abstract Article PDF–988K

Select item 217619412.

Loss of PIP5KIγ, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes

Yanfeng Wang, Rustem I. Litvinov, Xinsheng Chen, Tami L. Bach, Lurong Lian, Brian G. Petrich, Susan J. Monkley, David R. Critchley, Takehiko Sasaki, Morris J. Birnbaum, John W. Weisel, John Hartwig, Charles S. Abrams

J Clin Invest. 2008 Feb 1; 118(2): 812–819. doi: 10.1172/JCI34239

Correction in:: J Clin Invest. 2009 Feb 2; 119(2): 421.

PMCID:: PMC2176194

Abstract Article PDF–586K

Select item 23259513.

Complementation of growth factor receptor-dependent mitogenic signaling by a truncated type I phosphatidylinositol 4-phosphate 5-kinase.

J N Davis, C O Rock, M Cheng, J B Watson, R A Ashmun, H Kirk, R J Kay, M F Roussel

Mol Cell Biol. 1997 Dec; 17(12): 7398–7406. doi: 10.1128/mcb.17.12.7398

PMCID:: PMC232595

Summary PDF–829K

Select item 407451014.

The lipid kinase PIP5K1C regulates pain signaling and sensitization

Brittany D. Wright, Lipin Loo, Sarah E. Street, Anqi Ma, Bonnie Taylor-Blake, Michael A. Stashko, Jian Jin, William P. Janzen, Stephen V. Frye, Mark J. Zylka

Neuron. Author manuscript; available in PMC 2015 May 21.

Published in final edited form as: Neuron. 2014 May 21; 82(4): 836–847. doi: 10.1016/j.neuron.2014.04.006

PMCID:: PMC4074510

Abstract Article PDF–2.5M

Select item 293789815.

Phosphatidylinositol-4-Phosphate 5-Kinases and Phosphatidylinositol 4,5-Bisphosphate Synthesis in the Brain

Laura A. Volpicelli-Daley, Louise Lucast, Liang-Wei Gong, Lijuan Liu, Junko Sasaki, Takehiko Sasaki, Charles S. Abrams, Yasunori Kanaho, Pietro De Camilli

J Biol Chem. 2010 Sep 10; 285(37): 28708–28714. Published online 2010 Jul 9. doi: 10.1074/jbc.M110.132191

PMCID:: PMC2937898

Abstract Article PDF–1.1M

Select item 443012616.

Macrophages monitor tissue osmolarity and induce inflammatory response through NLRP3 and NLRC4 inflammasome activation

W. K. Eddie Ip, Ruslan Medzhitov

Nat Commun. Author manuscript; available in PMC 2015 Nov 11.

Published in final edited form as: Nat Commun. 2015; 6: 6931. Published online 2015 May 11. doi: 10.1038/ncomms7931

PMCID:: PMC4430126

Abstract Article PDF–2.0M

Select item 424873717.

Mice without MacroH2A Histone Variants

John R. Pehrson, Lakshmi N. Changolkar, Carl Costanzi, N. Adrian Leu

Mol Cell Biol. 2014 Dec; 34(24): 4523–4533. doi: 10.1128/MCB.00794-14

PMCID:: PMC4248737

Abstract Article PDF–1.1M

Select item 189911618.

A novel view of the transcriptome revealed from gene trapping in mouse embryonic stem cells

Guglielmo Roma, Gilda Cobellis, Pamela Claudiani, Francesco Maione, Pedro Cruz, Gaetano Tripoli, Marco Sardiello, Ivana Peluso, Elia Stupka

Genome Res. 2007 Jul; 17(7): 1051–1060. doi: 10.1101/gr.5720807

PMCID:: PMC1899116

Abstract Article PDF–739K

Select item 30876319.

GenePaint.org: an atlas of gene expression patterns in the mouse embryo

Axel Visel, Christina Thaller, Gregor Eichele

Nucleic Acids Res. 2004 Jan 1; 32(Database issue): D552–D556. doi: 10.1093/nar/gkh029

PMCID:: PMC308763

Abstract Article PDF–253K

Select item 16551120.

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells

Doug Stryke, Michiko Kawamoto, Conrad C. Huang, Susan J. Johns, Leslie A. King, Courtney A. Harper, Elaine C. Meng, Roy E. Lee, Alice Yee, Larry L'Italien, Pao-Tien Chuang, Stephen G. Young, William C. Skarnes, Patricia C. Babbitt, Thomas E. Ferrin

Nucleic Acids Res. 2003 Jan 1; 31(1): 278–281. doi: 10.1093/nar/gkg064

PMCID:: PMC165511

Abstract Article PDF–217K

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