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Select item 98040321.

Investigating the Role of DUSP4 in Uveal Melanoma

Karen Aughton, Dorota Sabat-Pośpiech, Samantha Barlow, Sarah E. Coupland, Helen Kalirai

Transl Vis Sci Technol. 2022 Dec; 11(12): 13. Published online 2022 Dec 28. doi: 10.1167/tvst.11.12.13

PMCID:: PMC9804032

Abstract Article PDF–1.2M

Select item 92950682.

Genome-Wide CRISPR/Cas9 Library Screening Identified that DUSP4 Deficiency Induces Lenvatinib Resistance in Hepatocellular Carcinoma

Shanzhou Huang, Zuyi Ma, Qi Zhou, Aimei Wang, Yuanfeng Gong, Zhenchong Li, Shujie Wang, Qian Yan, Dongping Wang, Baohua Hou, Chuanzhao Zhang

Int J Biol Sci. 2022; 18(11): 4357–4371. Published online 2022 Jul 4. doi: 10.7150/ijbs.69969

PMCID:: PMC9295068

Abstract Article PDF–4.0M

Select item 91101193.

Methylation of dual-specificity phosphatase 4 controls cell differentiation

Hairui Su, Ming Jiang, Chamara Senevirathne, Srinivas Aluri, Tuo Zhang, Han Guo, Juliana Xavier-Ferrucio, Shuiling Jin, Ngoc-Tung Tran, Szu-Mam Liu, Chiao-Wang Sun, Yongxia Zhu, Qing Zhao, Yuling Chen, LouAnn Cable, Yudao Shen, Jing Liu, Cheng-Kui Qu, Xiaosi Han, Christopher A. Klug, Ravi Bhatia, Yabing Chen, Stephen D. Nimer, Y. George Zheng, Camelia Iancu-Rubin, Jian Jin, Haiteng Deng, Diane S. Krause, Jenny Xiang, Amit Verma, Minkui Luo, Xinyang Zhao

Cell Rep. Author manuscript; available in PMC 2022 May 16.

Published in final edited form as: Cell Rep. 2021 Jul 27; 36(4): 109421. doi: 10.1016/j.celrep.2021.109421

PMCID:: PMC9110119

Abstract Article PDF–3.5M

Select item 79595614.

DUSP4 appears to be a highly localized endogenous inhibitor of epileptic signaling in human neocortex

A. Kirchner, S. Bagla, F. Dachet, JA Loeb

Neurobiol Dis. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: Neurobiol Dis. 2020 Nov; 145: 105073. Published online 2020 Sep 3. doi: 10.1016/j.nbd.2020.105073

PMCID:: PMC7959561

Abstract Article PDF–1.1M

Select item 78808015.

Low DUSP4 Expression Is Associated With Aggressive Phenotypes and Poor Prognosis in Gastric Cancer

SEONGSIK BANG, SEUNGYUN JEE, HYUNSUNG KIM, KISEOK JANG, HOSUB PARK, JAE KYUNG MYUNG, DONGHO CHOI, SU-JIN SHIN, SEUNG SAM PAIK

In Vivo. 2021 Jan-Feb; 35(1): 131–140. Published online 2021 Jan 3. doi: 10.21873/invivo.12240

PMCID:: PMC7880801

Abstract Article PDF–3.5M

Select item 68642806.

cAMP response element modulator α induces dual specificity protein phosphatase 4 to promote effector T cells in juvenile-onset Lupus

Sigrun R. Hofmann, Katrin Mäbert, Franz Kapplusch, Susanne Russ, Sarah Northey, Michael W. Beresford, George C. Tsokos, Christian M. Hedrich

J Immunol. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: J Immunol. 2019 Dec 1; 203(11): 2807–2816. Published online 2019 Oct 25. doi: 10.4049/jimmunol.1900760

PMCID:: PMC6864280

Abstract Article PDF–2.0M

Select item 57652937.

Downregulation of dual‐specificity phosphatase 4 enhances cell proliferation and invasiveness in colorectal carcinomas

Michihiro Ichimanda, Naoki Hijiya, Yoshiyuki Tsukamoto, Tomohisa Uchida, Chisato Nakada, Tomonori Akagi, Tsuyoshi Etoh, Hidekatsu Iha, Masafumi Inomata, Mutsuhiro Takekawa, Masatsugu Moriyama

Cancer Sci. 2018 Jan; 109(1): 250–258. Published online 2017 Dec 8. doi: 10.1111/cas.13444

PMCID:: PMC5765293

Abstract Article PDF–2.7M

Select item 54311278.

Sanguinarine inhibits growth and invasion of gastric cancer cells via regulation of the DUSP4/ERK pathway

Rui Zhang, Ge Wang, Peng‐Fei Zhang, Jing Zhang, Yan‐Xia Huang, Yun‐Min Lu, Wei Da, Qun Sun, Jin‐Shui Zhu

J Cell Mol Med. 2017 Jun; 21(6): 1117–1127. Published online 2016 Dec 13. doi: 10.1111/jcmm.13043

PMCID:: PMC5431127

Abstract Article PDF–1.4M

Select item 49634539.

Analysis of phosphatases in ER-negative breast cancers identifies DUSP4 as a critical regulator of growth and invasion

Abhijit Mazumdar, Graham M. Poage, Jonathan Shepherd, Anna Tsimelzon, Zachary C. Hartman, Petra Den Hollander, Jamal Hill, Yun Zhang, Jenny Chang, Susan G. Hilsenbeck, Suzanne Fuqua, C. Kent Osborne, Gordon B. Mills, Powel H. Brown

Breast Cancer Res Treat. 2016; 158: 441–454. Published online 2016 Jul 8. doi: 10.1007/s10549-016-3892-y

PMCID:: PMC4963453

Abstract Article PDF–3.9M

Select item 420053210.

Dual Specificity Phosphatase 4 Gene Expression in Association with Triple-Negative Breast Cancer Outcome

Michelle L Baglia, Qiuyin Cai, Ying Zheng, Jie Wu, Yinghao Su, Fei Ye, Ping-Ping Bao, Hui Cai, Zhiguo Zhao, Justin Balko, Wei Zheng, Wei Lu, Xiao-Ou Shu

Breast Cancer Res Treat. Author manuscript; available in PMC 2015 Nov 1.

Published in final edited form as: Breast Cancer Res Treat. 2014 Nov; 148(1): 211–220. Published online 2014 Oct 4. doi: 10.1007/s10549-014-3127-z

PMCID:: PMC4200532

Abstract Article PDF–131K

Select item 409014411.

Activation of MAPK pathways due to DUSP4 loss promotes cancer stem cell-like phenotypes in basal-like breast cancer

Justin M. Balko, Luis J. Schwarz, Neil E. Bhola, Richard Kurupi, Phillip Owens, Todd W. Miller, Henry Gómez, Rebecca S. Cook, Carlos L. Arteaga

Cancer Res. Author manuscript; available in PMC 2014 Oct 15.

Published in final edited form as: Cancer Res. 2013 Oct 15; 73(20): 6346–6358. Published online 2013 Aug 21. doi: 10.1158/0008-5472.CAN-13-1385

PMCID:: PMC4090144

Abstract Article PDF–2.2M

Select item 299289512.

Over-expression of mitogen-activated protein kinase phosphatase-2 enhances adhesion molecule expression and protects against apoptosis in human endothelial cells

Mashael Al-Mutairi, Sameer Al-Harthi, Laurence Cadalbert, Robin Plevin

Br J Pharmacol. 2010 Oct; 161(4): 782–798. doi: 10.1111/j.1476-5381.2010.00952.x

PMCID:: PMC2992895

Abstract Article PDF–1.8M

Select item 1081305913.

Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer’s Disease

Erming Wang, Allen L. Pan, Pritha Bagchi, Srikant Rangaraju, Nicholas T. Seyfried, Michelle E. Ehrlich, Stephen R. Salton, Bin Zhang

Biomolecules. 2024 Jan; 14(1): 66. Published online 2024 Jan 3. doi: 10.3390/biom14010066

PMCID:: PMC10813059

Abstract Article PDF–3.9M

Select item 1070988414.

ARID1A loss activates MAPK signaling via DUSP4 downregulation

Jayaprakash Mandal, Zheng-Cheng Yu, Ie-Ming Shih, Tian-Li Wang

J Biomed Sci. 2023; 30: 94. Published online 2023 Dec 9. doi: 10.1186/s12929-023-00985-5

PMCID:: PMC10709884

Abstract Article PDF–5.3M

Select item 922827115.

Metabolic Impact of MKP-2 Upregulation in Obesity Promotes Insulin Resistance and Fatty Liver Disease

Savanie Fernando, Jacob Sellers, Shauri Smith, Sarayu Bhogoju, Sadie Junkins, Morgan Welch, Orion Willoughby, Nabin Ghimire, Cassandra Secunda, Marina Barmanova, Sean C. Kumer, Kisuk Min, Ahmed Lawan

Nutrients. 2022 Jun; 14(12): 2475. Published online 2022 Jun 15. doi: 10.3390/nu14122475

PMCID:: PMC9228271

Abstract Article PDF–3.5M

Select item 798601116.

miR-122-5p suppresses the oncogenesis of PTC by inhibiting DUSP4 expression

Ning Hu, Yanhua Tian, Yanmei Song, Leilei Zang

Mol Med Rep. 2021 May; 23(5): 368. Published online 2021 Mar 16. doi: 10.3892/mmr.2021.12007

PMCID:: PMC7986011

Abstract Article PDF–1.0M

Select item 789368917.

The microRNA-429/DUSP4 axis regulates the sensitivity of colorectal cancer cells to nintedanib

Guohua Cheng, Yarong Li, Zhaoyu Liu, Xiang Song

Mol Med Rep. 2021 Apr; 23(4): 228. Published online 2021 Jan 25. doi: 10.3892/mmr.2021.11867

PMCID:: PMC7893689

Abstract Article PDF–5.7M

Select item 702891918.

Dual-specificity protein phosphatase DUSP4 regulates response to MEK inhibition in BRAF wild-type melanoma

Avinash Gupta, Christopher Towers, Frances Willenbrock, Roz Brant, Darren Richard Hodgson, Alan Sharpe, Paul Smith, Anthony Cutts, Anna Schuh, Ruth Asher, Kevin Myers, Sharon Love, Linda Collins, Adelyn Wise, Mark Roy Middleton, Valentine Moya Macaulay

Br J Cancer. 2020 Feb 18; 122(4): 506–516. Published online 2019 Dec 16. doi: 10.1038/s41416-019-0673-5

PMCID:: PMC7028919

Abstract Article PDF–1.4M

Select item 689281919.

miR-137 alleviates doxorubicin resistance in breast cancer through inhibition of epithelial-mesenchymal transition by targeting DUSP4

Feiya Du, Ling Yu, Ying Wu, Shuqian Wang, Jia Yao, Xiaoxiao Zheng, Shangzhi Xie, Shufeng Zhang, Xuemei Lu, Yu Liu, Wei Chen

Cell Death Dis. 2019 Dec; 10(12): 922. Published online 2019 Dec 4. doi: 10.1038/s41419-019-2164-2

PMCID:: PMC6892819

Abstract Article PDF–1.6M

Select item 591503520.

MiR-122-5p inhibits cell migration and invasion in gastric cancer by down-regulating DUSP4

Xiaofeng Xu, Feng Gao, Jianjiang Wang, Lan Tao, Jinsong Ye, Li Ding, Wei Ji, Xing Chen

Cancer Biol Ther. 2018; 19(5): 427–435. Published online 2018 Mar 6. doi: 10.1080/15384047.2018.1423925

PMCID:: PMC5915035

Abstract Article PDF–1.1M

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