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Select item 96466131.

Null Function of Npr1 Disturbs Immune Response in Colonic Inflammation During Early Postnatal Stage

Changkun Long, Hongfei Liu, Wenxing Zhan, Liping Chen, Andong Wu, Lin Yang, Shenghan Chen

Inflammation. 2022; 45(6): 2419–2432. Published online 2022 Jul 7. doi: 10.1007/s10753-022-01702-4

PMCID:: PMC9646613

Abstract Article PDF–3.7M

Select item 95696862.

Genetic Disruption of Guanylyl Cyclase/Natriuretic Peptide Receptor-A Triggers Differential Cardiac Fibrosis and Disorders in Male and Female Mutant Mice: Role of TGF-β1/SMAD Signaling Pathway

Umadevi Subramanian, Chandramohan Ramasamy, Samivel Ramachandran, Joshua M. Oakes, Jason D. Gardner, Kailash N. Pandey

Int J Mol Sci. 2022 Oct; 23(19): 11487. Published online 2022 Sep 29. doi: 10.3390/ijms231911487

PMCID:: PMC9569686

Abstract Article PDF–3.4M

Select item 88265353.

Guanylyl cyclase-A phosphorylation decreases cardiac hypertrophy and improves systolic function in male, but not female, mice

Brandon M. Wagner, Jerid W. Robinson, Chastity L. Healy, Madeline Gauthier, Deborah M. Dickey, Siu-Pok Yee, John W. Osborn, Timothy D. O’Connell, Lincoln R. Potter

FASEB J. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: FASEB J. 2022 Jan; 36(1): e22069. doi: 10.1096/fj.202100600RRR

PMCID:: PMC8826535

Abstract Article PDF–1.6M

Select item 87245634.

Empagliflozin Reduces Renal Hyperfiltration in Response to Uninephrectomy, but Is Not Nephroprotective in UNx/DOCA/Salt Mouse Models

Philipp Tauber, Frederick Sinha, Raffaela S. Berger, Wolfram Gronwald, Katja Dettmer, Michaela Kuhn, Maximilian Trum, Lars S. Maier, Stefan Wagner, Frank Schweda

Front Pharmacol. 2021; 12: 761855. Published online 2021 Dec 21. doi: 10.3389/fphar.2021.761855

PMCID:: PMC8724563

Abstract Article PDF–4.9M

Select item 77060005.

Cardiac-specific deletion of natriuretic peptide receptor A induces differential myocardial expression of circular RNA and mRNA molecules involved in metabolism in mice

Baoying Chen, Pan Chang, Xi Shen, Xiaomeng Zhang, Jing Zhang, Xihui Wang, Jun Yu

Mol Med Rep. 2021 Jan; 23(1): 50. Published online 2020 Nov 13. doi: 10.3892/mmr.2020.11688

PMCID:: PMC7706000

Abstract Article PDF–1.8M

Select item 71606716.

Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss

Philine Marchetta, Dorit Möhrle, Philipp Eckert, Katrin Reimann, Steffen Wolter, Arianna Tolone, Isabelle Lang, Markus Wolters, Robert Feil, Jutta Engel, François Paquet-Durand, Michaela Kuhn, Marlies Knipper, Lukas Rüttiger

Front Aging Neurosci. 2020; 12: 83. Published online 2020 Apr 9. doi: 10.3389/fnagi.2020.00083

PMCID:: PMC7160671

Abstract Article PDF–7.2M

Select item 66205907.

Genetic disruption of Npr1 depletes regulatory T cells and provokes high levels of proinflammatory cytokines and fibrosis in the kidneys of female mutant mice

Venkateswara Reddy Gogulamudi, Indra Mani, Umadevi Subramanian, Kailash N. Pandey

Am J Physiol Renal Physiol. 2019 Jun 1; 316(6): F1254–F1272. Published online 2019 Apr 3. doi: 10.1152/ajprenal.00621.2018

PMCID:: PMC6620590

Abstract Article

Select item 49672208.

Retinoic acid and sodium butyrate suppress the cardiac expression of hypertrophic markers and proinflammatory mediators in Npr1 gene-disrupted haplotype mice

Umadevi Subramanian, Prerna Kumar, Indra Mani, David Chen, Isaac Kessler, Ramu Periyasamy, Giri Raghavaraju, Kailash N. Pandey

Physiol Genomics. 2016 Jul 1; 48(7): 477–490. Published online 2016 May 6. doi: 10.1152/physiolgenomics.00073.2015

PMCID:: PMC4967220

Abstract Article

Select item 46758059.

Role of FQQI motif in the internalization, trafficking, and signaling of guanylyl-cyclase/natriuretic peptide receptor-A in cultured murine mesangial cells

Indra Mani, Renu Garg, Kailash N. Pandey

Am J Physiol Renal Physiol. 2016 Jan 1; 310(1): F68–F84. Published online 2015 Sep 16. doi: 10.1152/ajprenal.00205.2015

PMCID:: PMC4675805

Abstract Article

Select item 431276910.

Interactive roles of NPR1 gene-dosage and salt diets on cardiac angiotensin II, aldosterone and pro-inflammatory cytokines levels inmutantmice

Di Zhao, Subhankar Das, Kailash N. Pandey

J Hypertens. Author manuscript; available in PMC 2015 Feb 2.

Published in final edited form as: J Hypertens. 2013 Jan; 31(1): 134–144. doi: 10.1097/HJH.0b013e32835ac15f

PMCID:: PMC4312769

Abstract Article PDF–2.3M

Select item 398219411.

NPRA Signaling Regulates Stem Cell Recruitment and Angiogenesis: A Model to Study Linkage Between Inflammation and Tumorigenesis

Jaya Mallela, Sowndharya Ravi, Frantz Jean Louis, Bianca Mulaney, Michael Cheung, Ujjwala Sree Garapati, Vignesh Chinnasamy, Chunyan Wang, Srinivas Nagaraj, Shyam S Mohapatra, Subhra Mohapatra

Stem Cells. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: Stem Cells. 2013 Jul; 31(7): 1321–1329. doi: 10.1002/stem.1376

PMCID:: PMC3982194

Abstract Article PDF–7.1M

Select item 394536012.

Histone Deacetylase Inhibitors Modulate the Transcriptional Regulation of Guanylyl Cyclase/Natriuretic Peptide Receptor-A Gene: INTERACTIVE ROLES OF MODIFIED HISTONES, HISTONE ACETYLTRANSFERASE, p300, AND Sp1

Prerna Kumar, Satyabha Tripathi, Kailash N. Pandey

J Biol Chem. 2014 Mar 7; 289(10): 6991–7002. Published online 2014 Jan 22. doi: 10.1074/jbc.M113.511444

PMCID:: PMC3945360

Abstract Article PDF–3.0M

Select item 392973513.

Genetically Altered Mutant Mouse Models of Guanylyl Cyclase/Natriuretic Peptide Receptor-A Exhibit the Cardiac Expression of Proinflammatory Mediators in a Gene-Dose-Dependent Manner

Elangovan Vellaichamy, Subhankar Das, Umadevi Subramanian, Nobuyo Maeda, Kailash N. Pandey

Endocrinology. 2014 Mar; 155(3): 1045–1056. Published online 2014 Jan 3. doi: 10.1210/en.2013-1416

PMCID:: PMC3929735

Abstract Article

Select item 363671414.

ANF-RGC gene motif ⁶⁶⁹WTAPELL⁶⁷⁵ is vital for blood pressure regulation: Biochemical mechanism

Teresa Duda, Alexandre Pertzev, Rameshwar K. Sharma

Biochemistry. Author manuscript; available in PMC 2014 Apr 2.

Published in final edited form as: Biochemistry. 2013 Apr 2; 52(13): 2337–2347. Published online 2013 Mar 18. doi: 10.1021/bi400175d

PMCID:: PMC3636714

Abstract Article PDF–1.6M

Select item 356887415.

Atrial natriuretic peptide attenuates agonist-induced pulmonary edema in mice with targeted disruption of the gene for natriuretic peptide receptor-A

James R. Klinger, Shu-Whei Tsai, Sabrina Green, Katie L. Grinnell, Jason T. Machan, Elizabeth O. Harrington

J Appl Physiol (1985) 2013 Feb 1; 114(3): 307–315. Published online 2012 Nov 29. doi: 10.1152/japplphysiol.01249.2011

PMCID:: PMC3568874

Abstract Article

Select item 346649516.

Disruption of Npr1 gene differentially regulates the juxtaglomerular and distal tubular renin levels in null mutant mice

Minolfa C Prieto, Subhankar Das, Naveen K Somanna, Lisa M Harrison-Bernard, L Gabriel Navar, Kailash N Pandey

Int J Physiol Pathophysiol Pharmacol. 2012; 4(3): 128–139. Published online 2012 Sep 20.

PMCID:: PMC3466495

Abstract Article PDF–772K

Select item 338064717.

Natriuretic Peptide Receptor Guanylyl Cyclase-A Protects Podocytes from Aldosterone-Induced Glomerular Injury

Yoshihisa Ogawa, Masashi Mukoyama, Hideki Yokoi, Masato Kasahara, Kiyoshi Mori, Yukiko Kato, Takashige Kuwabara, Hirotaka Imamaki, Tomoko Kawanishi, Kenichi Koga, Akira Ishii, Takeshi Tokudome, Ichiro Kishimoto, Akira Sugawara, Kazuwa Nakao

J Am Soc Nephrol. 2012 Jul; 23(7): 1198–1209. doi: 10.1681/ASN.2011100985

PMCID:: PMC3380647

Abstract Article

Select item 310180718.

NPR-A regulates self-renewal and pluripotency of embryonic stem cells

E M Abdelalim, I Tooyama

Cell Death Dis. 2011 Mar; 2(3): e127. Published online 2011 Mar 10. doi: 10.1038/cddis.2011.10

PMCID:: PMC3101807

Abstract Article PDF–669K

Select item 299949419.

Targeted Disruption of Guanylyl Cyclase-A/Natriuretic Peptide Receptor-A Gene Provokes Renal Fibrosis and Remodeling in Null Mutant Mice: Role of Proinflammatory Cytokines

Subhankar Das, Edward Au, Stephen T. Krazit, Kailash N. Pandey

Endocrinology. 2010 Dec; 151(12): 5841–5850. Published online 2010 Sep 29. doi: 10.1210/en.2010-0655

PMCID:: PMC2999494

Abstract Article

Select item 294448420.

Phospholemman Ser69 phosphorylation contributes to sildenafil-induced cardioprotection against reperfusion injury

Melanie Madhani, Andrew R. Hall, Friederike Cuello, Rebecca L. Charles, Joseph R. Burgoyne, William Fuller, Adrian J. Hobbs, Michael J. Shattock, Philip Eaton

Am J Physiol Heart Circ Physiol. 2010 Sep; 299(3): H827–H836. Published online 2010 Jun 11. doi: 10.1152/ajpheart.00129.2010