PMC Links for Gene (Select 180086) - PMC

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Items: 18

Select item 53821721.

Mutational Analysis at Intersubunit Interfaces of an Anionic Glutamate Receptor Reveals a Key Interaction Important for Channel Gating by Ivermectin

Nurit Degani-Katzav, Revital Gortler, Marina Weissman, Yoav Paas

Front Mol Neurosci. 2017; 10: 92. Published online 2017 Apr 6. doi: 10.3389/fnmol.2017.00092

PMCID:: PMC5382172

Abstract Article PDF–3.0M

Select item 42559192.

X-ray structures of GluCl in apo states reveal gating mechanism of Cys-loop receptors

Thorsten Althoff, Ryan E. Hibbs, Surajit Banerjee, Eric Gouaux

Nature. Author manuscript; available in PMC 2015 Feb 21.

Published in final edited form as: Nature. 2014 Aug 21; 512(7514): 333–337. doi: 10.1038/nature13669

PMCID:: PMC4255919

Abstract Article PDF–5.9M

Select item 34411393.

A fluorescence-detection size-exclusion chromatography-based thermostability assay to identify membrane protein expression and crystallization conditions

Motoyuki Hattori, Ryan E. Hibbs, Eric Gouaux

Structure. Author manuscript; available in PMC 2013 Aug 8.

Published in final edited form as: Structure. 2012 Aug 8; 20(8): 1293–1299. doi: 10.1016/j.str.2012.06.009

PMCID:: PMC3441139

Abstract Article PDF–1.3M

Select item 32738494.

Natural variation in a chloride channel subunit confers avermectin resistance in C. elegans

Rajarshi Ghosh, Erik C. Andersen, Joshua A. Shapiro, Justin P. Gerke, Leonid Kruglyak

Science. Author manuscript; available in PMC 2012 Aug 3.

Published in final edited form as: Science. 2012 Feb 3; 335(6068): 574–578. doi: 10.1126/science.1214318

PMCID:: PMC3273849

Abstract Article PDF–1.1M

Select item 56732395.

Un-gating and allosteric modulation of a pentameric ligand-gated ion channel captured by molecular dynamics

Nicolas E Martin, Siddharth Malik, Nicolas Calimet, Jean-Pierre Changeux, Marco Cecchini

PLoS Comput Biol. 2017 Oct; 13(10): e1005784. Published online 2017 Oct 25. doi: 10.1371/journal.pcbi.1005784

PMCID:: PMC5673239

Abstract Article PDF–3.5M

Select item 37743706.

An Engineered Glutamate-gated Chloride (GluCl) Channel for Sensitive, Consistent Neuronal Silencing by Ivermectin

Shawnalea J. Frazier, Bruce N. Cohen, Henry A. Lester

J Biol Chem. 2013 Jul 19; 288(29): 21029–21042. Published online 2013 May 29. doi: 10.1074/jbc.M112.423921

PMCID:: PMC3774370

Abstract Article PDF–2.8M

Select item 32435477.

Molecular Determinants of Ivermectin Sensitivity at the Glycine Receptor Chloride Channel

Timothy Lynagh, Timothy I. Webb, Christine L. Dixon, Brett A. Cromer, Joseph W. Lynch

J Biol Chem. 2011 Dec 23; 286(51): 43913–43924. Published online 2011 Oct 27. doi: 10.1074/jbc.M111.262634

PMCID:: PMC3243547

Abstract Article PDF–1.9M

Select item 31604198.

Principles of activation and permeation in an anion-selective Cys-loop receptor

Ryan E. Hibbs, Eric Gouaux

Nature. Author manuscript; available in PMC 2011 Dec 2.

Published in final edited form as: Nature. 2011 Jun 2; 474(7349): 54–60. Published online 2011 May 15. doi: 10.1038/nature10139

PMCID:: PMC3160419

Abstract Article PDF–1.6M

Select item 100663659.

Nemacol is a small molecule inhibitor of C. elegans vesicular acetylcholine transporter with anthelmintic potential

Sean Harrington, Jacob Pyche, Andrew R. Burns, Tina Spalholz, Kaetlyn T. Ryan, Rachel J. Baker, Justin Ching, Lucien Rufener, Mark Lautens, Daniel Kulke, Alexandre Vernudachi, Mostafa Zamanian, Winnie Deuther-Conrad, Peter Brust, Peter J. Roy

Nat Commun. 2023; 14: 1816. Published online 2023 Mar 31. doi: 10.1038/s41467-023-37452-6

PMCID:: PMC10066365

Abstract Article PDF–4.1M

Select item 628754410.

Anthelmintic drug actions in resistant and susceptible C. elegans revealed by electrophysiological recordings in a multichannel microfluidic device

Janis C. Weeks, Kristin J. Robinson, Shawn R. Lockery, William M. Roberts

Int J Parasitol Drugs Drug Resist. 2018 Dec; 8(3): 607–628. Published online 2018 Oct 30. doi: 10.1016/j.ijpddr.2018.10.003

PMCID:: PMC6287544

Abstract Article PDF–4.5M

Select item 746675711.

A New Antagonist of Caenorhabditis elegans Glutamate-Activated Chloride Channels With Anthelmintic Activity

María Julia Castro, Ornella Turani, María Belén Faraoni, Darío Gerbino, Cecilia Bouzat

Front Neurosci. 2020; 14: 879. Published online 2020 Aug 19. doi: 10.3389/fnins.2020.00879

PMCID:: PMC7466757

Abstract Article PDF–443K

Select item 1598812.

The genetics of ivermectin resistance in Caenorhabditis elegans

Joseph A. Dent, McHardy M. Smith, Demetrios K. Vassilatis, Leon Avery

Proc Natl Acad Sci U S A. 2000 Mar 14; 97(6): 2674–2679. doi: 10.1073/pnas.97.6.2674

PMCID:: PMC15988

Abstract Article PDF–374K

Select item 478145813.

Ionotropic glutamate receptors: genetics, behavior and electrophysiology.

Penelope J Brockie, Andres V Maricq

WormBook. 2006 : 1–16. Published online 2006 Jan 19. doi: 10.1895/wormbook.1.61.1

PMCID:: PMC4781458

Abstract Article

Select item 782255214.

Temperature regulates synaptic subcellular specificity mediated by inhibitory glutamate signaling

Mengqing Wang, Daniel Witvliet, Mengting Wu, Lijun Kang, Zhiyong Shao

PLoS Genet. 2021 Jan; 17(1): e1009295. Published online 2021 Jan 11. doi: 10.1371/journal.pgen.1009295

PMCID:: PMC7822552

Abstract Article PDF–4.7M

Select item 278429715.

Pharmacogenetic Analysis Reveals a Post-Developmental Role for Rac GTPases in Caenorhabditis elegans GABAergic Neurotransmission

Cody J. Locke, Bwarenaba B. Kautu, Kalen P. Berry, S. Kyle Lee, Kim A. Caldwell, Guy A. Caldwell

Genetics. 2009 Dec; 183(4): 1357–1372. doi: 10.1534/genetics.109.106880

PMCID:: PMC2784297

Abstract Article PDF–2.8M

Select item 1015916816.

Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain

Faruk Dube, Andrea Hinas, Nicolas Delhomme, Magnus Åbrink, Staffan Svärd, Eva Tydén

PLoS One. 2023; 18(5): e0285262. Published online 2023 May 4. doi: 10.1371/journal.pone.0285262

PMCID:: PMC10159168

Abstract Article PDF–1.9M

Select item 310207717.

OrthoList: A Compendium of C. elegans Genes with Human Orthologs

Daniel D. Shaye, Iva Greenwald

PLoS One. 2011; 6(5): e20085. Published online 2011 May 25. doi: 10.1371/journal.pone.0020085

Correction in:: PLoS One. 2014; 9(1): 10.1371/annotation/f5ffb738-a176-4a43-b0e0-249cdea45fe0.

PMCID:: PMC3102077

Abstract Article PDF–530K

Select item 621659018.

OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes

Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye

Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307

PMCID:: PMC6216590

Abstract Article PDF–1.4M

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